Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function

Clinical diagnosis of Alzheimer's disease: Report of the NINCDS‐ADRDA Work Group* under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915 · see citing works

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assesment of Alzheimer's disease

Moms, J. C., Heyman, A., Mohs, R. C., Hughes, J. P., van Belle, G., Fillenbaum, G., Mellits, E. D., & Clark, C. (1989) · Neurology · doi:10.1212/wnl.39.9.1159 · Cited by 4,130 · see citing works

Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

Fillenbaum, G., & Heyman, A. (2002) · doi:10.1002/0470846410.ch42(iii · Cited by 2,859 · see citing works

Diabetes mellitus and the risk of dementia: The Rotterdam Study

Ott, A., Stolk, R. P., van Harskamp, F., Pols, H. A. P., Hofman, A., & Breteler, M. M. B. (1999) · Neurology · doi:10.1212/wnl.53.9.1937 · Cited by 2,175 · see citing works

The Clinical Diagnosis of Alzheimer's Disease

Wade, J. P. H., Mirsen, T. R., Hachinski, V. C., Fisman, M., Lau, C. S., & Merskey, H. (1987) · Archives of Neurology · doi:10.1001/archneur.1987.00520130016010 · Cited by 1,416 · see citing works

Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo

Farris, W., Mansourian, S., Chang, Y., Lindsley, L., Eckman, E., Frosch, M., Eckman, C., Tanzi, R., Selkoe, D., & Guénette, S. (2003) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.0230450100 · Cited by 1,361 · see citing works

Participation in Cognitively Stimulating Activities and Risk of Incident Alzheimer Disease

Wilson, R. S. (2002) · JAMA · doi:10.1001/jama.287.6.742 · Cited by 1,312 · see citing works

Type 2 Diabetes, APOE Gene, and the Risk for Dementia and Related Pathologies

Peila, R., Rodriguez, B. L., & Launer, L. J. (2002) · Diabetes · doi:10.2337/diabetes.51.4.1256 · Cited by 1,207 · see citing works

Natural history of mild cognitive impairment in older persons

Bennett, D. A., Wilson, R. S., Schneider, J. A., Evans, D. A., Beckett, L. A., Aggarwal, N. T., Barnes, L. L., Fox, J. H., & Bach, J. (2002) · Neurology · doi:10.1212/wnl.59.2.198 · Cited by 1,037 · see citing works

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part V. A normative study of the neuropsychological battery

Welsh, K. A., Butters, N., Mohs, R. C., Beekly, D., Edland, S., Fillenbaum, G., & Heyman, A. (1994) · Neurology · doi:10.1212/wnl.44.4.609 · Cited by 951 · see citing works

Cardiovascular risk factors and cognitive decline in middle-aged adults

Knopman, D., Boland, L. L., Mosley, T., Howard, G., Liao, D., Szklo, M., McGovern, P., & Folsom, A. R. (2001) · Neurology · doi:10.1212/wnl.56.1.42 · Cited by 883 · see citing works

Individual differences in rates of change in cognitive abilities of older persons.

Wilson, R. S., Beckett, L. A., Barnes, L. L., Schneider, J. A., Bach, J., Evans, D. A., & Bennett, D. A. (2002) · Psychology and Aging · doi:10.1037/0882-7974.17.2.179 · Cited by 842 · see citing works

Diabetes Mellitus and Risk of Alzheimer's Disease and Dementia with Stroke in a Multiethnic Cohort

Luchsinger, J. A. (2001) · American Journal of Epidemiology · doi:10.1093/aje/154.7.635 · Cited by 682 · see citing works

Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: Relationship to severity of dementia and apolipoprotein E genotype

Craft, S., Peskind, E., Schwartz, M. W., Schellenberg, G. D., Raskind, M., & Porte, D. (1998) · Neurology · doi:10.1212/wnl.50.1.164 · Cited by 560 · see citing works

Insulin and Insulin-like Growth Factor-1 Regulate Tau Phosphorylation in Cultured Human Neurons*

Hong, M., & Lee, V. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.31.19547 · Cited by 533 · see citing works

Depressive symptoms, cognitive decline, and risk of AD in older persons

Wilson, R. S., Barnes, L. L., Mendes de Leon, C. F., Aggarwal, N. T., Schneider, J. S., Bach, J., Pilat, J., Beckett, L. A., Arnold, S. E., Evans, D. A., et al. (2002) · Neurology · doi:10.1212/wnl.59.3.364 · Cited by 528 · see citing works

Is Diabetes Associated With Cognitive Impairment and Cognitive Decline Among Older Women?

Gregg, E. W. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.2.174 · Cited by 521 · see citing works

Evidence for Genetic Linkage of Alzheimer's Disease to Chromosome 10q

Bertram, L., Blacker, D., Mullin, K., Keeney, D. B., Jones, J., Basu, S., Yhu, S., McInnis, M. G., Go, R. C. P., Vekrellis, K., et al. (2000) · Science · doi:10.1126/science.290.5500.2302 · Cited by 519 · see citing works

Neurons Regulate Extracellular Levels of Amyloid β-Protein via Proteolysis by Insulin-Degrading Enzyme

Vekrellis, K., Ye, Z., Qiu, W. Q., Walsh, D. M., Hartley, D. M., Chesneau, V., Rosner, M. R., & Selkoe, D. J. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-05-01657.2000 · Cited by 495 · see citing works

Ageing and diabetes: implications for brain function

Biessels, G. J., van der Heide, L. P., Kamal, A., Bleys, R. L. A. W., & Gispen, W. H. (2002) · European Journal of Pharmacology · doi:10.1016/s0014-2999(02)01486-3 · Cited by 458 · see citing works

Advanced Glycation End Products in Alzheimer's Disease and Other Neurodegenerative Diseases

Sasaki, N., Fukatsu, R., Tsuzuki, K., Hayashi, Y., Yoshida, T., Fujii, N., Koike, T., WAKAYAMA, I., Yanagihara, R. T., Garruto, R. M., et al. (1998) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)65659-3 · Cited by 409 · see citing works

Linkage of Plasma Aβ42 to a Quantitative Locus on Chromosome 10 in Late-Onset Alzheimer's Disease Pedigrees

Ertekin‐Taner, N., Graff-Radford, N., Younkin, L. H., Eckman, C. B., Baker, M., Adamson, J. L., Ronald, J., Blangero, J., Hutton, M. L., & Younkin, S. G. (2000) · Science · doi:10.1126/science.290.5500.2303 · Cited by 370 · see citing works

Diabetes mellitus and the Risk of Dementia, Alzheimer’s Disease and Vascular Cognitive Impairment in the Canadian Study of Health and Aging

MacKnight, C., Rockwood, K., Awalt, E., & McDowell, I. (2002) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000064928 · Cited by 313 · see citing works

Enhancement of Memory in Alzheimer Disease With Insulin and Somatostatin, but Not Glucose

Craft, S., Asthana, S., Newcomer, J. W., Wilkinson, C. W., Matos, I. T., Baker, L. D., Cherrier, M., Lofgreen, C., Latendresse, S., Petrova, A., et al. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.12.1135 · Cited by 312 · see citing works

Relation of cerebral infarctions to dementia and cognitive function in older persons

Schneider, J. A., Wilson, R. S., Cochran, E. J., Bienias, J. L., Arnold, S. E., Evans, D. A., & Bennett, D. A. (2003) · Neurology · doi:10.1212/01.wnl.0000055863.87435.b2 · Cited by 305 · see citing works

Changes in Cognitive Abilities Over a 4-Year Period Are Unfavorably Affected in Elderly Diabetic Subjects

Fontbonne, A., Berr, C., Ducimetière, P., & Alpérovitch, A. (2001) · Diabetes Care · doi:10.2337/diacare.24.2.366 · Cited by 297 · see citing works

Apolipoprotein E ε4 allele, AD pathology, and the clinical expression of Alzheimer’s disease

Bennett, D. A., Wilson, R. S., Schneider, J. A., Evans, D. A., Aggarwal, N. T., Arnold, S. E., Cochran, E. J., Berry-Kravis, E., & Bienias, J. L. (2003) · Neurology · doi:10.1212/01.wnl.0000042478.08543.f7 · Cited by 282 · see citing works

Cognitive Activity in Older Persons From a Geographically Defined Population

Wilson, R. S., Bennett, D. A., Beckett, L. A., Morris, M. C., Gilley, D. W., Bienias, J. L., Scherr, P. A., & Evans, D. A. (1999) · The Journals of Gerontology Series B · doi:10.1093/geronb/54b.3.p155 · Cited by 232 · see citing works

Type 2 Diabetes and Cognitive Function in Community-Dwelling Elderly Women

Grodstein, F., Chen, J., Wilson, R. S., & Manson, J. E. (2001) · Diabetes Care · doi:10.2337/diacare.24.6.1060 · Cited by 223 · see citing works

Risk Factors for Cerebrovascular Disease as Correlates of Cognitive Function in a Stroke-Free Cohort

Desmond, D. W., Tatemichi, T. K., Paik, M. C., & Stern, Y. (1993) · Archives of Neurology · doi:10.1001/archneur.1993.00540020040015 · Cited by 201 · see citing works

The Apolipoprotein E ϵ4 Allele and Decline in Different Cognitive Systems During a 6-Year Period

Wilson, R. S., Schneider, J. A., Barnes, L. L., Beckett, L. A., Aggarwal, N. T., Cochran, E. J., Berry‐Kravis, E., Bach, J., Fox, J. H., Evans, D. A., et al. (2002) · Archives of Neurology · doi:10.1001/archneur.59.7.1154 · Cited by 192 · see citing works

Diabetics do not have increased Alzheimer-type pathology compared with age-matched control subjects

Heitner, J., & Dickson, D. (1997) · Neurology · doi:10.1212/wnl.49.5.1306 · Cited by 173 · see citing works

Change in Cognitive Function in Older Persons From a Community Population

Wilson, R. S., Beckett, L. A., Bennett, D. A., Albert, M., & Evans, D. A. (1999) · Archives of Neurology · doi:10.1001/archneur.56.10.1274 · Cited by 133 · see citing works

Insulin-like growth factor-1 and insulin mediate transient site-selective increases in tau phosphorylation in primary cortical neurons

Lesort, M. J., & Johnson, G. V. W. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00200-1 · Cited by 121 · see citing works

Diabetes and Cognitive Impairment: A Community-based Study of Elderly Subjects

Croxson, S. C. M., & Jagger, C. (1995) · Age and Ageing · doi:10.1093/ageing/24.5.421 · Cited by 91 · see citing works

Purified recombinant insulin-degrading enzyme degrades amyloid β-protein but does not promote its oligomerization

Chesneau, V., Vekrellis, K., Rosner, M. R., & Selkoe, D. J. (2000) · Biochemical Journal · doi:10.1042/bj3510509 · Cited by 91 · see citing works

A longitudinal study of cognitive performance in noninsulin dependent (type II) diabetic men

Robertson‐Tchabo, E. A., Arenberg, D., Tobin, J. D., & Plotz, J. B. (1986) · Experimental Gerontology · doi:10.1016/0531-5565(86)90051-3 · Cited by 62 · see citing works

Decline of Language Among Women and Men With Alzheimer's Disease

Hebert, L. E., Wilson, R. S., Gilley, D. W., Beckett, L. A., Scherr, P. A., Bennett, D. A., & Evans, D. A. (2000) · The Journals of Gerontology Series B · doi:10.1093/geronb/55.6.p354 · Cited by 55 · see citing works

The effect of insulin and glucose on the plasma concentration of Alzheimer's amyloid precursor protein

Boyt, A., Taddei, K., Hallmayer, J. F., Helmerhorst, E., Gandy, S., Craft, S., & Martins, R. N. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00458-3 · Cited by 46 · see citing works

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease

Sperling, R. A., Aisen, P. S., Beckett, L. A., Bennett, D. A., Craft, S., Fagan, A. M., Iwatsubo, T., Jack, C. R., Kaye, J., Montine, T. J., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.003 · Cited by 7,155 · see citing works

Alzheimer’s disease

Querfurth, H. W., & LaFerla, F. M. (2010) · New England Journal of Medicine · doi:10.1056/nejmra0909142 · Cited by 4,569 · see citing works

Risk of dementia in diabetes mellitus: a systematic review

Biessels, G. J., Staekenborg, S., Brunner, E., Brayne, C., & Scheltens, P. (2006) · The Lancet Neurology · doi:10.1016/s1474-4422(05)70284-2 · Cited by 2,187 · see citing works

Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention

Qiu, C., Kivipelto, M., & von Strauss, E. (2009) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2009.11.2/cqiu · Cited by 1,261 · see citing works

Cognitive decline and dementia in diabetes—systematic overview of prospective observational studies

Cukierman, T., Gerstein, H. C., & Williamson, J. D. (2005) · Diabetologia · doi:10.1007/s00125-005-0023-4 · Cited by 1,049 · see citing works

Insulin and neurodegenerative disease: shared and specific mechanisms

Craft, S., & Stennis Watson, G. (2004) · The Lancet Neurology · doi:10.1016/s1474-4422(04)00681-7 · Cited by 830 · see citing works

Type 2 diabetes as a risk factor for dementia in women compared with men: a pooled analysis of 2·3 million people comprising more than 100,000 cases of dementia

Chatterjee, S., Peters, S. A. E., Woodward, M., Mejia Arango, S., Batty, G. D., Beckett, N., Beiser, A., Borenstein, A. R., Crane, P. K., Haan, M., et al. (2016) · Diabetes Care · doi:10.2337/dc15-1588 · Cited by 711 · see citing works

Diabetes mellitus and risk of dementia: A meta‐analysis of prospective observational studies

Gudala, K., Bansal, D., Schifano, F., & Bhansali, A. (2013) · Journal of Diabetes Investigation · doi:10.1111/jdi.12087 · Cited by 727 · see citing works

Meta-analysis of Alzheimer’s disease risk with obesity, diabetes, and related disorders

Profenno, L. A., Porsteinsson, A. P., & Faraone, S. V. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.02.013 · Cited by 718 · see citing works

Cognitive impairment in hemodialysis patients is common

Murray, A. M., Tupper, D. E., Knopman, D. S., Gilbertson, D. T., Pederson, S. L., Li, S., Smith, G. E., Hochhalter, A. K., Collins, A. J., & Kane, R. L. (2006) · Neurology · doi:10.1212/01.wnl.0000225182.15532.40 · Cited by 712 · see citing works

Sleep deprivation as a neurobiologic and physiologic stressor: allostasis and allostatic load

McEwen, B. S. (2006) · Metabolism · doi:10.1016/j.metabol.2006.07.008 · Cited by 624 · see citing works

GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

Li, Y., Perry, T., Kindy, M. S., Harvey, B. K., Tweedie, D., Holloway, H. W., Powers, K., Shen, H., Egan, J. M., Sambamurti, K., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806720106 · Cited by 589 · see citing works

Obesity and central obesity as risk factors for incident dementia and its subtypes: a systematic review and meta‐analysis

Beydoun, M. A., Beydoun, H. A., & Wang, Y. (2008) · Obesity Reviews · doi:10.1111/j.1467-789x.2008.00473.x · Cited by 563 · see citing works

Physical frailty is associated with incident mild cognitive impairment in community-based older persons

Boyle, P. A., Buchman, A. S., Wilson, R. S., Leurgans, S. E., & Bennett, D. A. (2010) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2009.02671.x · Cited by 510 · see citing works

Brain abnormalities in human obesity: A voxel-based morphometric study

Pannacciulli, N., Del Parigi, A., Chen, K., Le, D. S. N. T., Reiman, E. M., & Tataranni, P. A. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.01.047 · Cited by 523 · see citing works

From pre-diabetes to diabetes: diagnosis, treatments and translational research

Khan, R., Chua, Z., Tan, J., Yang, Y., Liao, Z., & Zhao, Y. (2019) · Medicina · doi:10.3390/medicina55090546 · Cited by 484 · see citing works

How does diabetes accelerate Alzheimer disease pathology?

Sims-Robinson, C., Kim, B., Rosko, A., & Feldman, E. L. (2010) · Nature Reviews Neurology · doi:10.1038/nrneurol.2010.130 · Cited by 492 · see citing works

Insulin resistance is associated with the pathology of Alzheimer disease: The Hisayama Study

Matsuzaki, T., Sasaki, K., Tanizaki, Y., Hata, J., Fujimi, K., Matsui, Y., Sekita, A., Suzuki, S. O., Kanba, S., Kiyohara, Y., et al. (2010) · Neurology · doi:10.1212/wnl.0b013e3181eee25f · Cited by 432 · see citing works

Frailty is associated with incident Alzheimer's disease and cognitive decline in the elderly

Buchman, A. S., Boyle, P. A., Wilson, R. S., Tang, Y., & Bennett, D. A. (2007) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318068de1d · Cited by 420 · see citing works

Ozone, Particulate Matter, and Newly Diagnosed Alzheimer's Disease: A Population-Based Cohort Study in Taiwan

Jung, C.-R., Lin, Y.-T., & Hwang, B.-F. (2015) · Journal of Alzheimer's Disease · doi:10.3233/jad-140855 · Cited by 380 · see citing works

An updated meta-analysis of cohort studies: Diabetes and risk of Alzheimer’s disease

Zhang, J., Chen, C., Hua, S., Liao, H., Wang, M., Xiong, Y., & Cao, F. (2017) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2016.10.024 · Cited by 376 · see citing works

Diabetes and other vascular risk factors for dementia: Which factor matters most? A systematic review

Kloppenborg, R. P., van den Berg, E., Kappelle, L. J., & Biessels, G. J. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2008.02.049 · Cited by 368 · see citing works

Common pathological processes in Alzheimer disease and type 2 diabetes: A review

Li, L., & Hölscher, C. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.09.001 · Cited by 367 · see citing works

Sleep Deprivation and Circadian Disruption

McEwen, B. S., & Karatsoreos, I. N. (2015) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2014.11.007 · Cited by 338 · see citing works

Gut to Brain Dysbiosis: Mechanisms Linking Western Diet Consumption, the Microbiome, and Cognitive Impairment

Noble, E. E., Hsu, T. M., & Kanoski, S. E. (2017) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2017.00009 · Cited by 333 · see citing works

Alzheimer's disease as type 3 diabetes: common pathophysiological mechanisms between Alzheimer's disease and type 2 diabetes

Michailidis, M., Moraitou, D., Tata, D. A., Kalinderi, K., Papamitsou, T., & Papaliagkas, V. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052687 · Cited by 330 · see citing works

Insulin-degrading Enzyme as a Downstream Target of Insulin Receptor Signaling cascade: Implications for Alzheimer's Disease Intervention

Zhao, L., Teter, B., Morihara, T., Lim, G. P., Ambegaokar, S. S., Ubeda, O. J., Frautschy, S. A., & Cole, G. M. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.2860-04.2004 · Cited by 329 · see citing works

Type 2 Diabetes as a Risk Factor for Alzheimer's Disease: The Confounders, Interactions, and Neuropathology Associated With This Relationship

Vagelatos, N. T., & Eslick, G. D. (2013) · Epidemiologic Reviews · doi:10.1093/epirev/mxs012 · Cited by 320 · see citing works

Type 2 diabetes mellitus and Alzheimer’s disease

Barbagallo, M. (2014) · World Journal of Diabetes · doi:10.4239/wjd.v5.i6.889 · Cited by 313 · see citing works

Revenge of the “Sit”: How lifestyle impacts neuronal and cognitive health through molecular systems that interface energy metabolism with neuronal plasticity

Vaynman, S., & Gomez‐Pinilla, F. (2006) · Journal of Neuroscience Research · doi:10.1002/jnr.20979 · Cited by 299 · see citing works

Therapy insight, type 2 diabetes mellitus and the risk of late-onset Alzheimer's disease

Haan, M. N. (2006) · Nature Clinical Practice Neurology · doi:10.1038/ncpneuro0124 · Cited by 284 · see citing works

Mid- and Late-Life Diabetes in Relation to the Risk of Dementia

Xu, W., Qiu, C., Gatz, M., Pedersen, N. L., Johansson, B., & Fratiglioni, L. (2009) · Diabetes · doi:10.2337/db08-0586 · Cited by 284 · see citing works

A transdisciplinary perspective of chronic stress in relation to psychopathology throughout life span development

Juster, R.-P., Bizik, G., Picard, M., Arsenault-Lapierre, G., Sindi, S., Trepanier, L., Marin, M.-F., Wan, N., Sekerovic, Z., Lord, C., et al. (2011) · Development and Psychopathology · doi:10.1017/s0954579411000289 · Cited by 268 · see citing works

Immune aging, dysmetabolism, and inflammation in neurological diseases

Deleidi, M., Jäggle, M., & Rubino, G. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00172 · Cited by 260 · see citing works

Clearance mechanisms of Alzheimer's amyloid-β peptide: implications for therapeutic design and diagnostic tests

Bates, K. A., Verdile, G., Li, Q.-X., Ames, D., Hudson, P., Masters, C. L., & Martins, R. N. (2009) · Molecular Psychiatry · doi:10.1038/mp.2008.96 · Cited by 247 · see citing works

11β-Hydroxysteroid dehydrogenases and the brain: From zero to hero, a decade of progress

Wyrwoll, C. S., Holmes, M. C., & Seckl, J. R. (2011) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.12.001 · Cited by 244 · see citing works

Is Alzheimer’s disease a systemic disease?

Morris, J. K., Honea, R. A., Vidoni, E. D., Swerdlow, R. H., & Burns, J. M. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2014.04.012 · Cited by 219 · see citing works

A look inside the diabetic brain: Contributors to diabetes-induced brain aging

Wrighten, S. A., Piroli, G. G., Grillo, C. A., & Reagan, L. P. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2008.10.013 · Cited by 195 · see citing works

Cardiovascular Risk Factors and Incident Alzheimer Disease: A Systematic Review of the Literature

Purnell, C., Gao, S., Callahan, C. M., & Hendrie, H. C. (2009) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0b013e318187541c · Cited by 189 · see citing works

Insulin in the nervous system and the mind: Functions in metabolism, memory, and mood

Lee, S.-H., Zabolotny, J. M., Huang, H., Lee, H., & Kim, Y.-B. (2016) · Molecular Metabolism · doi:10.1016/j.molmet.2016.06.011 · Cited by 176 · see citing works

Adiposity, hyperinsulinemia, diabetes and Alzheimer's disease

Luchsinger, J. A. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2008.02.048 · Cited by 171 · see citing works

Cinnamon extract inhibits tau aggregation associated with Alzheimer’s disease in vitro

Peterson, D. W., George, R. C., Scaramozzino, F., LaPointe, N. E., Anderson, R. A., Graves, D. J., & Lew, J. (2009) · Journal of Alzheimer s Disease · doi:10.3233/jad-2009-1083 · Cited by 171 · see citing works

Glucose Intolerance, Insulin Resistance, and Pathological Features of Alzheimer Disease in the Baltimore Longitudinal Study of Aging

Thambisetty, M., Metter, E. J., Yang, A., Dolan, H., Marano, C., Zonderman, A. B., Troncoso, J. C., Zhou, Y., Wong, D. F., Ferrucci, L., et al. (2013) · JAMA Neurology · doi:10.1001/jamaneurol.2013.284 · Cited by 155 · see citing works

Vascular risk factors and cognitive impairment in a stroke-free cohort

Unverzagt, F. W., McClure, L. A., Wadley, V. G., Jenny, N. S., Go, R. C., Cushman, M., Kissela, B. M., Kelley, B. J., Kennedy, R., Moy, C. S., et al. (2011) · Neurology · doi:10.1212/wnl.0b013e318236ef23 · Cited by 152 · see citing works

Physical Activity, Cognitive Activity, and Cognitive Decline in a Biracial Community Population

Sturman, M. T., Morris, M. C., Mendes de Leon, C. F., Bienias, J. L., Wilson, R. S., & Evans, D. A. (2005) · Archives of Neurology · doi:10.1001/archneur.62.11.1750 · Cited by 142 · see citing works

Type 2 diabetes mellitus, dyslipidemia, and Alzheimer’s disease

Carlsson, C. M. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-100012 · Cited by 109 · see citing works

Alzheimer’s Disease and Inflammaging

Kosyreva, A., Sentyabreva, A., Tsvetkov, I., & Makarova, O. (2022) · Brain Sciences · doi:10.3390/brainsci12091237 · Cited by 98 · see citing works

Potential benefits of mindfulness-based interventions in mild cognitive impairment and Alzheimer’s disease: an interdisciplinary perspective.

Larouche, E., Hudon, C., & Goulet, S. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.05.058 · Cited by 93 · see citing works

Type 2 diabetes, related conditions, in relation and dementia: An opportunity for prevention?

Luchsinger, J. A. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-091687 · Cited by 91 · see citing works

Metabolism, mood and cognition in aging: the importance of lifestyle and dietary intervention

Hendrickx, H., McEwen, B. S., & Ouderaa, F. V. D. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.10.005 · Cited by 83 · see citing works

State of the science on brain insulin resistance and cognitive decline due to Alzheimer's disease

Rhea, E. M., Leclerc, M., Yassine, H. N., Capuano, A. W., Tong, H., Petyuk, V. A., Macauley, S. L., Fioramonti, X., Carmichael, O., Calon, F., et al. (2023) · Aging and disease · doi:10.14336/ad.2023.0814 · Cited by 70 · see citing works

Selected Findings from the Religious Orders Study and Rush Memory and Aging Project

Bennett, D. A., Wilson, R. S., Arvanitakis, Z., Boyle, P. A., de Toledo-Morrell, L., & Schneider, J. A. (2012) · Journal of Alzheimer's Disease · doi:10.3233/jad-2012-129007 · Cited by 69 · see citing works

Metformin activation of AMPK suppresses AGE-induced inflammatory response in hNSCs

Chung, M.-M., Nicol, C. J., Cheng, Y.-C., Lin, K.-H., Chen, Y.-L., Pei, D., Lin, C.-H., Shih, Y.-N., Yen, C.-H., Chen, S.-J., et al. (2017) · Experimental Cell Research · doi:10.1016/j.yexcr.2017.01.017 · Cited by 66 · see citing works

Effect of a long-term intensive lifestyle intervention on cognitive function: Action for Health in Diabetes study

Rapp, S. R., Luchsinger, J. A., Baker, L. D., Blackburn, G. L., Hazuda, H. P., Demos‐McDermott, K. E., Jeffery, R. W., Keller, J. N., McCaffery, J. M., Pajewski, N. M., et al. (2017) · Journal of the American Geriatrics Society · doi:10.1111/jgs.14692 · Cited by 62 · see citing works

Antidiabetic drugs for Alzheimer's and Parkinson's diseases: Repurposing insulin, metformin, and thiazolidinediones

(2020) · International Review of Neurobiology · doi:10.1016/bs.irn.2020.02.010 · Cited by 58 · see citing works

Effects of Alzheimer's amyloid-beta and tau protein on mitochondrial function — role of glucose metabolism and insulin signalling

Rhein, V., & Eckert, A. (2007) · Archives of Physiology and Biochemistry · doi:10.1080/13813450701572288 · Cited by 56 · see citing works

ACTIVE cognitive training and rates of incident dementia

Unverzagt, F. W., Guey, L. T., Jones, R. N., Marsiske, M., King, J. W., Wadley, V. G., Crowe, M., Rebok, G. W., & Tennstedt, S. L. (2012) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617711001470 · Cited by 56 · see citing works

High glucose induces formation of tau hyperphosphorylation via Cav-1-mTOR pathway: A potential molecular mechanism for diabetes-induced cognitive dysfunction

Wu, J., Zhou, S.-L., Pi, L.-H., Shi, X.-J., Ma, L.-R., Chen, Z., Qu, M.-L., Li, X., Nie, S.-D., Liao, D.-F., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.17257 · Cited by 50 · see citing works

Insulin-mediated cortical activity in the slow frequency range is diminished in obese mice and promotes physical inactivity

Hennige, A. M., Sartorius, T., Lutz, S. Z., Tschritter, O., Preissl, H., Hopp, S., Fritsche, A., Rammensee, H.-G., Ruth, P., & Häring, H.-U. (2009) · Diabetologia · doi:10.1007/s00125-009-1522-5 · Cited by 41 · see citing works

Metformin and Its Sulfenamide Prodrugs Inhibit Human Cholinesterase Activity

Markowicz-Piasecka, M., Sikora, J., Mateusiak, Ł., Mikiciuk-Olasik, E., & Huttunen, K. M. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/7303096 · Cited by 32 · see citing works

Activation of Macrophages and Microglia by Interferon-γ and Lipopolysaccharide Increases Methylglyoxal Production: A New Mechanism in the Development of Vascular Complications and Cognitive Decline in Type 2 Diabetes Mellitus?

Dhananjayan, K., Gunawardena, D., Hearn, N., Sonntag, T., Moran, C., Gyengesi, E., Srikanth, V., & Münch, G. (2017) · Journal of Alzheimer s Disease · doi:10.3233/jad-161152 · Cited by 24 · see citing works

Cumulative Genetic Risk and <i>APOE ε4</i> Are Independently Associated With Dementia Status in a Multiethnic, Population-Based Cohort

Bakulski, K. M., Vadari, H. S., Faul, J. D., Heeringa, S. G., Kardia, S. L. R., Langa, K. M., Smith, J. A., Manly, J. J., Mitchell, C. M., Benke, K. S., et al. (2021) · Neurology Genetics · doi:10.1212/nxg.0000000000000576 · Cited by 20 · see citing works

The Relationship Between the Continuum of Elevated Adiposity, Hyperinsulinemia, and Type 2 Diabetes and Late-onset Alzheimer’s Disease: An Epidemiological Perspective

Luchsinger, J. A. (2010) · Research and Perspectives in Alzheimer's Disease · doi:10.1007/978-3-642-04300-0_7 · Cited by 3 · see citing works

Replay of Episodic Memories in the Rat

Panoz-Brown, D., Iyer, V., Carey, L. M., Sluka, C. M., Rajic, G., Kestenman, J., Gentry, M., Brotheridge, S., Somekh, I., Corbin, H. E., et al. (2018) · Current Biology · doi:10.1016/j.cub.2018.04.006 · Cited by 101 · see citing works

Episodic autobiographical memory is associated with variation in the size of hippocampal subregions

Palombo, D. J., Bacopulos, A., Amaral, R. S. C., Olsen, R. K., Todd, R. M., Anderson, A. K., & Levine, B. (2017) · Hippocampus · doi:10.1002/hipo.22818 · Cited by 48 · see citing works

The mnemonic functions of episodic memory

Boyle, A. (2022) · Philosophical Psychology · doi:10.1080/09515089.2021.1980520 · Cited by 27 · see citing works

Episodic memory: what can animals remember about their past?

Griffiths, D., Dickinson, A., & Clayton, N. (1999) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(98)01272-8 · Cited by 228 · see citing works

Episodic recollection in animals: “if it walks like a duck and quacks like a duck ….”

Eichenbaum, H., Fortin, N. J., Ergorul, C., Wright, S. P., & Agster, K. L. (2005) · Learning and Motivation · doi:10.1016/j.lmot.2005.02.006 · Cited by 72 · see citing works