2D and 3D Cell Cultures - a Comparison of Different Types of Cancer Cell Cultures

Matrix elasticity directs stem cell lineage specification

Engler, A. J., Sen, S., Sweeney, H. L., & Discher, D. E. (2006) · Cell · doi:10.1016/j.cell.2006.06.044 · Cited by 13,915

The third dimension bridges the gap between cell culture and live tissue

Pampaloni, F., Reynaud, E. G., & Stelzer, E. H. K. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2236 · Cited by 2,817

Exploring and Engineering the Cell Surface Interface

Stevens, M. M., & George, J. H. (2005) · Science · doi:10.1126/science.1106587 · Cited by 2,607

Capturing complex 3D tissue physiology in vitro

Griffith, L. G., & Swartz, M. A. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1858 · Cited by 2,347

Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines.

Scudiero, D. A., Shoemaker, R. H., Paull, K. D., Monks, A. P., Tierney, S., Nofziger, T. H., Currens, M. J., Seniff, D. A., & Boyd, M. R. (1988) · PubMed · Cited by 2,342

Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels

Benya, P. D., & Shaffer, J. D. (1982) · Cell · doi:10.1016/0092-8674(82)90027-7 · Cited by 2,284

Geometric cues for directing the differentiation of mesenchymal stem cells

Kilian, K. A., Bugarija, B., Lahn, B. T., & Mrksich, M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903269107 · Cited by 1,841

Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues

Baker, B. M., & Chen, C. S. (2012) · Journal of Cell Science · doi:10.1242/jcs.079509 · Cited by 1,760

Modeling Tissue Morphogenesis and Cancer in 3D

Yamada, K. M., & Cukierman, E. (2007) · Cell · doi:10.1016/j.cell.2007.08.006 · Cited by 1,751

Spheroid-based drug screen: Considerations and practical approach

Friedrich, J., Seidel, C., Ebner, R., & Kunz-Schughart, L. A. (2009) · Nature Protocols · doi:10.1038/nprot.2008.226 · Cited by 1,742

Anticancer and Antiangiogenic Activities of Novel α-Mangostin Glycosides in Human Hepatocellular Carcinoma Cells via Downregulation of c-Met and HIF-1α

Kim, S. M., Han, J. M., Le, T. T., Sohng, J. K., & Jung, H. J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21114043 · Cited by 21

Development and Validation of a Long-Term 3D Glioblastoma Cell Culture in Alginate Microfibers as a Novel Bio-Mimicking Model System for Preclinical Drug Testing

Dragoj, M., Stojkovska, J., Stanković, T., Dinić, J., Podolski-Renić, A., Obradović, B., & Pešić, M. (2021) · Brain Sciences · doi:10.3390/brainsci11081025 · Cited by 21

Profiling the 3D interaction between germ cell tumors and microenvironmental cells at the transcriptome and secretome level

Skowron, M. A., Eul, K., Stephan, A., Ludwig, G. F., Wakileh, G. A., Bister, A., Söhngen, C., Raba, K., Petzsch, P., Poschmann, G., et al. (2022) · Molecular Oncology · doi:10.1002/1878-0261.13282 · Cited by 20

Extracellular Vesicles in Breast Cancer: From Intercellular Communication to Therapeutic Opportunities

Barathan, M., Ng, S. L., Lokanathan, Y., Ng, M. H., & Law, J. X. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16050654 · Cited by 20

Modification in Structures of Active Compounds in Anticancer Mitochondria-Targeted Therapy

Felczykowska, A., & Herman-Antosiewicz, A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26031376 · Cited by 21

Hydrogel membranes in organ-on-a-chip devices: A review

Gnatowski, P., Ansariaghmiuni, M., Piłat, E., Poostchi, M., Kucińska‐Lipka, J., Yazdi, M. K., Ryl, J., Ashrafizadeh, M., Mottaghitalab, F., Farokhi, M., et al. (2025) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2025.114591 · Cited by 22

Establishing 3D organoid models from patient-derived conditionally reprogrammed cells to bridge preclinical and clinical insights in pancreatic cancer

Kim, J. S., Park, C. H., Kim, E., Lee, H. S., Lee, J.-Y., Kim, J., Kam, E. H., Nam, S., Chung, M. J., Park, J. Y., et al. (2025) · Molecular Cancer · doi:10.1186/s12943-025-02374-y · Cited by 20

Calcium phosphate scaffolds with defined interconnecting channel structure provide a mimetic 3D niche for bone marrow metastasized tumor cell growth

Aveic, S., Davtalab, R., Vogt, M., Weber, M. H., Buttler, P., Tonini, G. P., & Fischer, H. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.02.030 · Cited by 20

Simplified Bioprinting-Based 3D Cell Culture Infection Models for Virus Detection

Koban, R., Lam, T., Schwarz, F., Kloke, L., Bürge, S., Ellerbrok, H., & Neumann, M. (2020) · Viruses · doi:10.3390/v12111298 · Cited by 21

A novel TGF-β receptor II mutation (I227T/N236D) promotes aggressive phenotype of oral squamous cell carcinoma via enhanced EGFR signaling

Son, H., Kim, D., Lim, Y., Kim, J., & Park, I. (2020) · BMC Cancer · doi:10.1186/s12885-020-07669-5 · Cited by 20

Three-dimensional spheroid culture induces apical-basal polarity and the original characteristics of immortalized human renal proximal tubule epithelial cells

Mizuguchi, K., Aoki, H., Aoyama, M., Kawaguchi, Y., Waguri‐Nagaya, Y., Ohte, N., & Asai, K. (2021) · Experimental Cell Research · doi:10.1016/j.yexcr.2021.112630 · Cited by 20

Biparatopic Protein Nanoparticles for the Precision Therapy of CXCR4+ Cancers

Cano‐Garrido, O., Álamo, P., Sánchez‐García, L., Falgàs, A., Sánchez‐Chardi, A., Serna, N., Parladé, E., Unzueta, U., Roldán, M., Voltà‐Durán, E., et al. (2021) · Cancers · doi:10.3390/cancers13122929 · Cited by 20

3D Modeling of Epithelial Tumors—The Synergy between Materials Engineering, 3D Bioprinting, High-Content Imaging, and Nanotechnology

Trivedi, P., Liu, R., Bi, H., Xu, C., Rosenholm, J. M., & Åkerfelt, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126225 · Cited by 20

From organ-on-chip to body-on-chip: The next generation of microfluidics platforms for in vitro drug efficacy and toxicity testing

Lacombe, J., Soldevila, M., & Zenhausern, F. (2022) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2021.07.019 · Cited by 20

Validation of CD98hc as a Therapeutic Target for a Combination of Radiation and Immunotherapies in Head and Neck Squamous Cell Carcinoma

Köseer, A. S., Loureiro, L. R., Jureczek, J., Mitwasi, N., Soto, K. E. G., Aepler, J., Bartsch, T., Feldmann, A., Kunz‐Schughart, L. A., Linge, A., et al. (2022) · Cancers · doi:10.3390/cancers14071677 · Cited by 21

Urinary Tract Tumor Organoids Reveal Eminent Differences in Drug Sensitivities When Compared to 2-Dimensional Culture Systems

Wei, Y., Amend, B., Todenhöfer, T., Lipke, N., Aicher, W. K., Fend, F., Stenzl, A., & Harland, N. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23116305 · Cited by 20

Investigation of reversible histone acetylation and dynamics in gene expression regulation using 3D liver spheroid model

Stransky, S., Cutler, R. R., Aguilan, J. T., Nieves, E., & Sidoli, S. (2022) · Epigenetics & Chromatin · doi:10.1186/s13072-022-00470-7 · Cited by 21

New Frontiers in Three-Dimensional Culture Platforms to Improve Diabetes Research

Mohandas, S., Gayatri, V., Kumaran, K., Gopinath, V., Paulmurugan, R., & Ramkumar, K. M. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15030725 · Cited by 21

COMMD3 loss drives invasive breast cancer growth by modulating copper homeostasis

Hancock, J. L., Kalimutho, M., Straube, J., Lim, M., Gresshoff, I. L., Saunus, J. M., Lee, J. S., Lakhani, S. R., Simpson, K. J., Bush, A. I., et al. (2023) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-023-02663-8 · Cited by 20

SERS-Active Printable Hydrogel for 3D Cell Culture and Imaging

Wang, W., & Vikesland, P. J. (2023) · Analytical Chemistry · doi:10.1021/acs.analchem.3c02641 · Cited by 20

Dose-Dependent Effects of Radiation on Mitochondrial Morphology and Clonogenic Cell Survival in Human Microvascular Endothelial Cells

Wang, L., Rivas, R., Wilson, A., Park, Y. M., Walls, S., Yu, T., & Miller, A. C. (2023) · Cells · doi:10.3390/cells13010039 · Cited by 20

Towards Automation in 3D Cell Culture: Selective and Gentle High‐Throughput Handling of Spheroids and Organoids via Novel Pick‐Flow‐Drop Principle

Zieger, V., Frejek, D., Zimmermann, S., Miotto, G., Koltay, P., Zengerle, R., & Kartmann, S. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202303350 · Cited by 20

Utilizing human cerebral organoids to model breast cancer brain metastasis in culture

Wang, C., Nagayach, A., Patel, H., Dao, L., Zhu, H., Wasylishen, A. R., Fan, Y., Kendler, A., & Guo, Z. (2024) · Breast Cancer Research · doi:10.1186/s13058-024-01865-y · Cited by 20

Exploring the Potential of Drug Response Assays for Precision Medicine in Ovarian Cancer

Singh, T., Neal, A. S., Moatamed, N. A., & Memarzadeh, S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms22010305 · Cited by 23

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment

Ko, J., Meyer, A. N., Haas, M., & Donoghue, D. J. (2021) · Oncotarget · doi:10.18632/oncotarget.27859 · Cited by 20

3D Tissue Models as an Effective Tool for Studying Viruses and Vaccine Development

Lawko, N., Plaskasovitis, C., Stokes, C., Abelseth, L., Fraser, I. S., Sharma, R., Kirsch, R. L., Hasan, M., Abelseth, E., & Willerth, S. M. (2021) · Frontiers in Materials · doi:10.3389/fmats.2021.631373 · Cited by 21

Establishment and characterization of meningioma patient-derived organoid

Chan, H. S. C., Ng, H., Chan, A. K., Cheng, S. H., Chow, C., Wong, N., & Wong, G. K. C. (2021) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2021.10.035 · Cited by 20

The potential application of organoids in breast cancer research and treatment

Ebrahimi, N., Esfahani, A. N., Samizade, S., Mansouri, A., Ghanaatian, M., Adelian, S., Shadman-Manesh, V., & Hamblin, M. R. (2021) · Human Genetics · doi:10.1007/s00439-021-02390-0 · Cited by 20

Three-Dimensional Cell Culture Models of Hepatocellular Carcinoma — a Review

Ayvaz, I., Sunay, D., Sarıyar, E., Erdal, E., & Karagonlar, Z. F. (2021) · Journal of Gastrointestinal Cancer · doi:10.1007/s12029-021-00772-1 · Cited by 21

Biomimicked hierarchical 2D and 3D structures from natural templates: applications in cell biology

Yadav, S., & Majumder, A. (2021) · Biomedical Materials · doi:10.1088/1748-605x/ac21a7 · Cited by 19

Transcending Dimensions in Apicomplexan Research: from Two-Dimensional to Three-Dimensional In Vitro Cultures

Ramírez‐Flores, C. J., Perdomo, A. M. T., Gallego-López, G. M., & Knoll, L. J. (2022) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00025-22 · Cited by 19

High-throughput widefield fluorescence imaging of 3D samples using deep learning for 2D projection image restoration

Forsgren, E., Edlund, C., Oliver, M., Barnes, K., Sjögren, R., & Jackson, T. R. (2022) · PLoS ONE · doi:10.1371/journal.pone.0264241 · Cited by 19

Different Expression of Thyroid-Specific Proteins in Thyroid Cancer Cells between 2-Dimensional (2D) and 3-Dimensional (3D) Culture Environment

Oh, J. M., Gangadaran, P., Rajendran, R. L., Hong, C. M., Lee, J., & Ahn, B. (2022) · Cells · doi:10.3390/cells11223559 · Cited by 19

Ultrashort Peptide-Based Hydrogel for the Healing of Critical Bone Defects in Rabbits

Yadav, N., Kumar, U., Roopmani, P., Krishnan, U. M., Sethuraman, S., Chauhan, M. K., & Chauhan, V. S. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c18733 · Cited by 19

Controlling Microenvironments with Organs-on-Chips for Osteoarthritis Modelling

Ong, L. J. Y., Fan, X., Sun, A. R., Mei, L., Toh, Y., & Prasadam, I. (2023) · Cells · doi:10.3390/cells12040579 · Cited by 20

Interface self-referenced dynamic full-field optical coherence tomography

Monfort, T., Azzollini, S., Yacoub, T. B., Audo, I. S., Reichman, S., Grieve, K. F., & Thouvenin, O. (2023) · Biomedical Optics Express · doi:10.1364/boe.488663 · Cited by 19

A Microfluidic Organ-On-A-Chip: Into the Next Decade of Bone Tissue Engineering Applied in Dentistry

Syahruddin, M. H., Anggraeni, R., & Ana, I. D. (2023) · Future Science OA · doi:10.2144/fsoa-2023-0061 · Cited by 20

Mimicking sarcolemmal damage in vitro: a contractile 3D model of skeletal muscle for drug testing in Duchenne muscular dystrophy

Tejedera‐Villafranca, A., Montolio, M., Ramón‐Azcón, J., & Fernández‐Costa, J. M. (2023) · Biofabrication · doi:10.1088/1758-5090/acfb3d · Cited by 20

3D bioprinted GelMA platform for the production of lung tumor spheroids

Villata, S., Canta, M., Baruffaldi, D., Roppolo, I., Pirri, C. F., & Frascella, F. (2023) · Bioprinting · doi:10.1016/j.bprint.2023.e00310 · Cited by 19

Encapsulation of Human Spinal Cord Progenitor Cells in Hyaluronan-Gelatin Hydrogel for Spinal Cord Injury Treatment

Kwokdinata, C., Ramanujam, V., Chen, J., Oliveira, P. F., Nai, M. H., Chooi, W. H., Lim, C. T., Ng, S., David, L., & Chew, S. Y. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c07419 · Cited by 19

Organoid models: the future companions of personalized drug development

Piraino, F., Costa, M., Meyer, M., Cornish, G. H., Ceroni, C., Garnier, V., Hoehnel, S., & Brandenberg, N. (2024) · Biofabrication · doi:10.1088/1758-5090/ad3e30 · Cited by 21

In Vitro 3D Cultures to Reproduce the Bone Marrow Niche

Ham, J., Lever, L., Fox, M., & Reagan, M. R. (2019) · JBMR Plus · doi:10.1002/jbm4.10228 · Cited by 22

Frequency of CD44 positive cells in MKN45 cell line after treatment with docetaxel in two and three-dimensional cell cultures

Alizadeh, A., Rezakhani, L., Anjomshoa, M., & Ghasemi, S. (2019) · Tissue and Cell · doi:10.1016/j.tice.2019.101324 · Cited by 20

The preparation of cell-containing microbubble scaffolds to mimic alveoli structure as a 3D drug-screening system for lung cancer

Sun, Y., Hsu, C., Ling, T., Liu, L., Lin, T.-C., Jakfar, S., Young, I.-C., & Lin, F. (2020) · Biofabrication · doi:10.1088/1758-5090/ab78ee · Cited by 19

The Effects of Serum Removal on Gene Expression and Morphological Plasticity Markers in Differentiated SH-SY5Y Cells

Thomson, A. C., Schuhmann, T., de Graaf, T. A., Sack, A. T., Rutten, B. P. F., & Kenis, G. (2021) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-021-01062-x · Cited by 19

Leveraging advances in immunopathology and artificial intelligence to analyze in vitro tumor models in composition and space

Leong, T. K. M., Lo, W. S., Lee, W. E. Z., Tan, B., Lee, X. Z., Lee, L. W. J. N., Lee, J.-Y. J., Suresh, N., Loo, L., Szu, E., et al. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.113959 · Cited by 19

Pharmacometabolomics Applied to Personalized Medicine in Urological Cancers

Amaro, F., Carvalho, M. C., Bastos, M. D. L., de Pinho, P. G., & Pinto, J. (2022) · Pharmaceuticals · doi:10.3390/ph15030295 · Cited by 20

Hypoxia-inducing cryogels uncover key cancer-immune cell interactions in an oxygen-deficient tumor microenvironment

Colombani, T., Rogers, Z. J., Bhatt, K., Sinoimeri, J., Gerbereux, L., Hamrangsekachaee, M., & Bencherif, S. A. (2023) · Bioactive Materials · doi:10.1016/j.bioactmat.2023.06.021 · Cited by 19

Low-frequency magnetic field therapy for glioblastoma: Current advances, mechanisms, challenges and future perspectives

Liu, Y., Tang, Q., Tao, Q., Dong, H., Shi, Z., & Zhou, L. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2024.03.024 · Cited by 18

Expanding the Prostate Cancer Cell Line Repertoire with ACRJ-PC28, an AR-negative Neuroendocrine Cell Line Derived From an African-Caribbean Patient

Valentine, H., Aiken, W. D., Morrison, B. F., Zhao, Z., Fowle, H. A., Wasserman, J. S., Thompson, E., Chin, W., Young, M. A., Clarke, S., et al. (2022) · Cancer Research Communications · doi:10.1158/2767-9764.crc-22-0245 · Cited by 18

Recent Advances in Modeling Tissues Using 3D Bioprinted Nanocellulose Bioinks

Walters-Shumka, J. P., Cheng, C., Jiang, F., & Willerth, S. M. (2025) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.4c01902 · Cited by 18

Immune Organoids: A Review of Their Applications in Cancer and Autoimmune Disease Immunotherapy

Olawade, D. B., Oisakede, E. O., Egbon, E., Ovsepian, S. V., & Boussios, S. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47080653 · Cited by 20

Three-Dimensional, Scaffolded Tumor Model to Study Cell-Driven Microenvironment Effects and Therapeutic Responses

Ornell, K. J., Mistretta, K. S., Newman, E. A., Ralston, C. Q., & Coburn, J. M. (2019) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.9b01267 · Cited by 18

The Molecular Basis of Different Approaches for the Study of Cancer Stem Cells and the Advantages and Disadvantages of a Three-Dimensional Culture

Cianciosi, D., Ansary, J., Forbes-Hernández, T. Y., Regolo, L., Quinzi, D., Villar, S. G., Villena, E. G., Pifarré, K. T., Álvarez-Suárez, J. M., Battino, M. A., et al. (2021) · Molecules · doi:10.3390/molecules26092615 · Cited by 18

Reproducible In Vitro Tissue Culture Model to Study Basic Mechanisms of Calcific Aortic Valve Disease: Comparative Analysis to Valvular Interstitials Cells

Weber, A., Pfaff, M., Schoettler, F. I., Schmidt, V., Lichtenberg, A., & Akhyari, P. (2021) · Biomedicines · doi:10.3390/biomedicines9050474 · Cited by 20

Central nervous system tumors and three-dimensional cell biology: Current and future perspectives in modeling

Abou-Mrad, Z., Bou-Gharios, J., Moubarak, M. M., Chalhoub, A., Moussalem, C. K., Bahmad, H. F., & Abou-Kheir, W. G. (2021) · World Journal of Stem Cells · doi:10.4252/wjsc.v13.i8.1112 · Cited by 18

Cell spheroids containing bioactive molecule-immobilized porous particles with a leaf-stacked structure

Kim, M. J., Jeoung, Y. J., Kim, H. Y., Kim, S. Y., Kim, J., Park, J. W., Byun, J., Lee, J. H., & Oh, S. H. (2021) · Chemical Engineering Journal · doi:10.1016/j.cej.2021.132590 · Cited by 18

G9a inhibition by CM-272: Developing a novel anti-tumoral strategy for castration-resistant prostate cancer using 2D and 3D in vitro models

Moreira‐Silva, F., Outeiro-Pinho, G., Lobo, J., Guimarães, R., Gaspar, V. M., Mano, J. F., Agirre, X., Pineda‐Lucena, A., Prósper, F., Paramio, J. M., et al. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113031 · Cited by 18

Chemoresistance in pancreatic ductal adenocarcinoma: Overcoming resistance to therapy

Bhoopathi, P., Mannangatti, P., Das, S. K., Fisher, P. B., & Emdad, L. (2023) · Advances in cancer research · doi:10.1016/bs.acr.2023.02.010 · Cited by 19

Recapitulating the Drifting and Fusion of Two-Generation Spheroids on Concave Agarose Microwells

Pan, R., Yang, X., Ning, K., Xie, Y., Chen, F., & Yu, L. D. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241511967 · Cited by 20

Expression of polymeric immunoglobulin receptor (PIGR) and the effect of PIGR overexpression on breast cancer cells

Asanprakit, W., Lobo, D. N., Eremin, O., & Bennett, A. J. (2023) · Scientific Reports · doi:10.1038/s41598-023-43946-6 · Cited by 18

Advancing Tissue Culture with Light-Driven 3D-Printed Microfluidic Devices

Li, X., Wang, M., Davis, T. P., Zhang, L., & Qiao, R. (2024) · Biosensors · doi:10.3390/bios14060301 · Cited by 18

iPSC-derived lung and lung cancer organoid model to evaluate cisplatin encapsulated autologous iPSC-derived mesenchymal stromal cell-isolated extracellular vesicles

Küstermann, C., Narbute, K., Movčana, V., Parfejevs, V., Rūmnieks, F., Kauķis, P., Priedols, M., Mikilps-Mikgelbs, R., Mihailova, M., Andersone, S., et al. (2024) · Stem Cell Research & Therapy · doi:10.1186/s13287-024-03862-6 · Cited by 18

PGRMC2 and HLA-G regulate immune homeostasis in a microphysiological model of human maternal-fetal membrane interface

Lintao, R. C. V., Richardson, L., Kammala, A. K., Chapa, J., Yap, D. Y., Khanipov, K., Golovko, G., Dalmacio, L. M. M., & Menon, R. (2024) · Communications Biology · doi:10.1038/s42003-024-06740-2 · Cited by 18

N3-MEA Probes: Scooping Neuronal Networks

Kireev, D., Montes, V. R., Stevanovic, J., Srikantharajah, K., & Offenhäusser, A. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00320 · Cited by 18

Pre-clinical 2D and 3D toxicity response to a panel of nanomaterials; comparative assessment of NBM-induced liver toxicity

Tutty, M. A., Vella, G., & Prina‐Mello, A. (2022) · Drug Delivery and Translational Research · doi:10.1007/s13346-022-01170-1 · Cited by 19

Protocol to create isogenic disease models from adult stem cell-derived organoids using next-generation CRISPR tools

Celotti, M., Derks, L. L. M., van Es, J., van Boxtel, R., Clevers, H., & Geurts, M. H. (2024) · STAR Protocols · doi:10.1016/j.xpro.2024.103189 · Cited by 17

Nanophotosensitizers for cancer therapy: a promising technology?

dos Santos, A. F., Arini, G. S., de Almeida, D. R. Q., & Labriola, L. (2021) · Journal of Physics Materials · doi:10.1088/2515-7639/abf7dd · Cited by 17

Culture and characterization of canine and feline corneal epithelial organoids: A new tool for the study and treatment of corneal diseases

Bedos, L., Wickham, H., Gabriel, V., Zdyrski, C., Allbaugh, R. A., Sahoo, D. K., Sebbag, L., Mochel, J. P., & Allenspach, K. (2022) · Frontiers in Veterinary Science · doi:10.3389/fvets.2022.1050467 · Cited by 17

Oxidative Status as an Attribute for Selective Antitumor Activity of Platinum-Containing Nanoparticles against Hepatocellular Carcinoma

Wawrowicz, K., Majkowska‐Pilip, A., Szwed, M., Żelechowska-Matysiak, K., Chajduk, E., & Bilewicz, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232314773 · Cited by 17

Cancer Cell Culture: The Basics and Two-Dimensional Cultures

Tutty, M. A., Holmes, S., & Prina‐Mello, A. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-3056-3_1 · Cited by 17

3D multicellular tumor spheroids used for in vitro preclinical therapeutic screening

Roy, S. M., Kishore, P., Saha, D., Ghosh, P., Kar, R., Barman, S., Agrawal, V., Roy, A., Deb, R., Chakraborty, S. S., et al. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.104636 · Cited by 18

Multicomponent-Loaded Vesosomal Drug Carrier for Controlled and Sustained Compound Release

Lee, D., Song, S., Kim, S., Lee, M., Kim, E., Yoon, S., Kim, H., Son, S., Jung, H. S., Huh, Y. S., et al. (2023) · Biomacromolecules · doi:10.1021/acs.biomac.3c00528 · Cited by 17

Next-generation analytical platforms for antioxidant capacity assessment: The urge for realistic and physiologically relevant methods

Granato, D. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115155 · Cited by 17

2D and 3D in vitro angiogenesis assays highlight different aspects of angiogenesis

Rapp, J., Ness, J. N., Wolf, J., Hospach, A., Liang, P., Hug, M. J., Agostini, H. T., Schlunck, G., Lange, C., & Bucher, F. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2024.167028 · Cited by 17

Dual-crosslinking gelatin-hyaluronic acid methacrylate based biomimetic PDAC desmoplastic niche enhances tumor-associated macrophages recruitment and M2-like polarization

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