The DOI matches its Crossref record; 98 of the 98 references it cites were found in a registry or an index.
Engineering exosomes for targeted drug delivery
Open accessAbstract
Exosomes are cell-derived nanovesicles that are involved in the intercellular transportation of materials. Therapeutics, such as small molecules or nucleic acid drugs, can be incorporated into exosomes and then delivered to specific types of cells or tissues to realize targeted drug delivery. Targeted delivery increases the local concentration of therapeutics and minimizes side effects. Here, we present a detailed review of exosomes engineering through genetic and chemical methods for targeted drug delivery. Although still in its infancy, exosome-mediated drug delivery boasts low toxicity, low immunogenicity, and high engineerability, and holds promise for cell-free therapies for a wide range of diseases.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Two main approaches can be used to enhance the targeting ability of exosomes for specific applications: direct modification of exosomes by chemical means or, indirect manipulation of the donor cells through genetic engineering techniques [89, 103, 118–120]”
From Exosome for mRNA delivery: Strategies and therapeutic applications (2024) · cites this paper as [119]
In the citing paper
“Unlike synthetic nanocarriers such as liposomes or polymer-based systems, exosomes are less likely to trigger adverse reactions, making them a safer option for therapeutic applications [26].”
From Emerging role of exosomes in cancer therapy: progress and challenges (2025) · cites this paper as [26]
In the citing paper
“Exosomes can deliver small molecules to targeted cells or tissues for targeted therapy and improve therapy accuracy and efficacy [26].”
From Emerging role of exosomes in cancer therapy: progress and challenges (2025) · cites this paper as [26]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
1 retracted
Rana, S., Yue, S., Stadel, D., & Zöller, M. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2012.06.018 · Cited by 688
RetractedThéry, C., Witwer, K. W., Aikawa, E., Alcaraz, M. J., Anderson, J. D., Andriantsitohaina, R., Antoniou, A., Arab, T., Archer, F., Atkin‐Smith, G. K., et al. (2018) · Journal of Extracellular Vesicles · doi:10.1080/20013078.2018.1535750 · Cited by 11,099
The biology , function , and biomedical applications of exosomes
Kalluri, R., & LeBleu, V. S. (2020) · Science · doi:10.1126/science.aau6977 · Cited by 10,770
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
Alvarez-Erviti, L., Seow, Y., Yin, H., Betts, C., Lakhal, S., & Wood, M. J. A. (2011) · Nature Biotechnology · doi:10.1038/nbt.1807 · Cited by 4,930
Mathieu, M., Jaular, L. M., Lavieu, G., & Théry, C. (2018) · Nature Cell Biology · doi:10.1038/s41556-018-0250-9 · Cited by 3,863
Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
Trajković, K., Hsu, C., Chiantia, S., Rajendran, L., Wenzel, D., Wieland, F., Schwille, P., Brügger, B., & Simons, M. (2008) · Science · doi:10.1126/science.1153124 · Cited by 3,760
Reassessment of exosome composition
Jeppesen, D. K., Fenix, A. M., Franklin, J. L., Higginbotham, J. N., Zhang, Q., Zimmerman, L. J., Liebler, D. C., Ping, J., Liu, Q., Evans, R., et al. (2019) · Cell · doi:10.1016/j.cell.2019.02.029 · Cited by 2,975
Johnstone, R. M., Adam, M., Hammond, J. R., Orr, L., & Turbide, C. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)48095-7 · Cited by 2,931
Routes and mechanisms of extracellular vesicle uptake
Mulcahy, L. A., Pink, R. C., & Carter, D. R. F. (2014) · Journal of Extracellular Vesicles · doi:10.3402/jev.v3.24641 · Cited by 2,832
Identification and proteomic profiling of exosomes in human urine
Pisitkun, T., Shen, R., & Knepper, M. A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403453101 · Cited by 2,162
Flagged first, then by citations
Cited by
Sorted by citations
Items 901–1,000 of 1,000
Biologics-based technologies for highly efficient and targeted RNA delivery
Kostyusheva, A., Brezgin, S., Ponomareva, N., Frolova, A., Lunin, A., Олеговна, Б. Е., Tikhonov, A., Slatinskaya, O. V., Demina, P. A., Kachanov, A., et al. (2024) · Molecular Therapy · doi:10.1016/j.ymthe.2024.11.004 · Cited by 10
Chen, W., Xu, W., Ma, L., Bi, C., Yang, M., & Yang, W. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1513196 · Cited by 7
León, C. G. A.-D., & Thomson, A. W. (2025) · Transplantation · doi:10.1097/tp.0000000000005309 · Cited by 7
Adapted Exosomes for Addressing Chemotherapy-induced Premature Ovarian Insufficiency
Ghasroldasht, M. M., Park, H.-S., Ali, F. L., Beckman, A., Mohammadi, M., Hafner, N., & Al-Hendy, A. A. (2025) · Stem Cell Reviews and Reports · doi:10.1007/s12015-024-10820-5 · Cited by 12
Met-Exo attenuates pyroptosis in miniature pig liver IRI by improving mitochondrial quality control
Cao, L., Li, P. A., Liu, T., Ma, Y., Lu, X., & Wang, H. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.114437 · Cited by 10
Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis
Wang, Y., Li, Y., Zhang, Y., Li, C., Lin, Y., Chen, S., & Han, B. (2025) · BMEMat · doi:10.1002/bmm2.70017 · Cited by 9
Advances of exosome regulating‑FXR to repair inflammatory bowel disease (Review)
Muro, P., Jing, C., Qiao, Y., Wang, W., Wang, B., & Mao, F. (2025) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2025.5576 · Cited by 7
Engineered exosome based immunomodulation therapies: Advancements and clinical applications
Qazi, R., Rehman, F. U., Rehman, A., & Mian, A. A. (2025) · Nano Biomedicine and Engineering · doi:10.1016/j.nbe.2025.100005 · Cited by 9
Biological Nanoparticles for Enhancing Chronic Wound Regeneration
Zotikov, D., Ponomareva, N. I., Brezgin, S., Kostyusheva, A., Frolova, A. S., Chulanov, V., Lukashev, A. N., Timashev, P. S., & Kostyushev, D. S. (2025) · Cells · doi:10.3390/cells14201637 · Cited by 7
Chen, S., Di, J., Zhang, Z., Guo, Z., Tian, Z., Qin, Y., Long, Y., Xu, J., Xiang, C., & Cao, F. (2025) · International Journal of Nanomedicine · doi:10.2147/ijn.s549684 · Cited by 9
Liu, X.-Q. N., & Sheng, R. N. (2025) · Journal of Integrative Neuroscience · doi:10.31083/jin47443 · Cited by 9
Li, M., 王婷婷, Zhang, Z., & Dongye, Y. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1742855 · Cited by 9
An, W., Jin, Z., & Li, Y. (2026) · Frontiers in Neurology · doi:10.3389/fneur.2025.1708655 · Cited by 8
Engineering the Future: Strategic Advances in Extracellular Vesicle-Mediated Drug Delivery Systems
Zhang, X., & Zhang, X. (2026) · International Journal of Nanomedicine · doi:10.2147/ijn.s583242 · Cited by 9
Kamra, K., Lalam, S. K., Srivastava, S., Arumugam, M. K., Boopathy, L. K., Takkar, S., Xia, Z., & Subramanian, S. P. (2026) · Health Science Reports · doi:10.1002/hsr2.72638 · Cited by 8
Engineered 4-OI-loaded exosomes guide M/Ms glycolysis against ischemic stroke in aged rats
Xu, C., Gao, H., Cui, J., Teng, P., Zhao, H.-S., Tian, H., Lin, S., & Liu, C. (2022) · Materials & Design · doi:10.1016/j.matdes.2022.110943 · Cited by 7
Targeted expression of a designed fusion protein containing BMP2 into the lumen of exosomes
Masjedi, M. N.-K., Sadroddiny, E., Ai, J., Balalaie, S., & Asgari, Y. (2023) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2023.130505 · Cited by 7
Li, S., Wu, Y., Peng, X., Chen, H., Zhang, T., Chen, H., Yang, J., Xie, Y., Qi, H., Xiang, W., et al. (2023) · Advanced Science · doi:10.1002/advs.202306143 · Cited by 7
Mansur, A., & Radovanovic, I. (2024) · Frontiers in Genetics · doi:10.3389/fgene.2024.1348096 · Cited by 7
Enhancing the therapeutic efficacy of NK cells in the treatment of ovarian cancer (Review)
Hou, Y., Zhao, X., & Nie, X. (2024) · Oncology Reports · doi:10.3892/or.2024.8709 · Cited by 7
Nanotechnology‐Fortified Manipulation of Cell Ca 2+ Signaling
Zhou, Y., Zhang, Z., Zhou, C., Ma, Y., Huang, H., Liu, J., & Zhu, D. (2024) · Small Science · doi:10.1002/smsc.202400169 · Cited by 7
Jia, R., Lu, J., Sun, B., Zhang, K., Wang, N., Wen, Y., & Ma, J. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.135654 · Cited by 8
Self-citationRetractedNie, L., Ma, J., Yu, Y., Tao, Y., Song, Z., & Li, J. (2024) · Biochemical Pharmacology · doi:10.1016/j.bcp.2024.116699 · Cited by 8
Gao, Q., Su, Z., Pang, X., Chen, J., Luo, R., Li, X., Zhang, C., & Zhao, Y. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04651-1 · Cited by 7
Natural endogenous material-based vehicles for delivery of macromolecular drugs.
Lu, A., Du, K., Wang, M., Zhu, Z., Lei, L., & Shi, Y. (2024) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(24)60742-9 · Cited by 10
Milk-derived exosome-loaded SS31 as a novel strategy to mitigate UV-induced photodamage in skin
Luo, D., Mao, Y., Zhang, S., Shen, S., Ge, X., & Zhang, L. (2025) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2025.113125 · Cited by 7
Chemoresistance and immune evasion in hepatocellular carcinoma: the role of miRNA-425-5p
Pan, X., Liu, J., Zhang, Y., Sun, C., & Li, Y. (2025) · Carcinogenesis · doi:10.1093/carcin/bgaf012 · Cited by 7
Lizama-Muñoz, A., & Plaza‐Díaz, J. (2025) · Biomolecules · doi:10.3390/biom15050639 · Cited by 7
Cheng, J., Rong, G., Wang, Z., Liu, S., Yang, Q., Liu, W., Zhang, D., & Li, J. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/3450672 · Cited by 7
RetractedGuru, S. A., Saha, P., Chen, L., Tulshyan, A., Ge, Z., Baily, J., Simons, L., Stefanowicz, A., Bilewska, A., Mehta, V., et al. (2023) · Stem Cell Reviews and Reports · doi:10.1007/s12015-023-10565-7 · Cited by 6
The influence of amphiphilic carbosilane dendrons on lipid model membranes
Wróbel, D., Edr, A., Zemanova, E., Strašák, T., Semerádtová, A., & Malý, J. (2023) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2023.105314 · Cited by 7
Zheng, X., Zhao, D., Liu, Y., Jin, Y., Liu, T., Li, H., & Liu, D. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115739 · Cited by 7
Function of macrophage-derived exosomes in chronic liver disease: From pathogenesis to treatment
Xiang, S.-Y., Deng, K., Yang, D., Yang, P., & Zhou, Y. (2023) · World Journal of Hepatology · doi:10.4254/wjh.v15.i11.1196 · Cited by 7
Exosomes: Friends or Foes in Microbial Infections?
Teymouri, S., Pourhajibagher, M., & Bahador, A. (2024) · Infectious Disorders - Drug Targets · doi:10.2174/0118715265264388231128045954 · Cited by 8
Enhancing extracellular vesicles for therapeutic treatment of arthritic joints
Austin‐Williams, S., Hussain, M. T., Oggero, S., & Norling, L. V. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.08.235 · Cited by 7
Gupta, S. K., & Mazumder, P. B. (2022) · Advances in clinical chemistry · doi:10.1016/bs.acc.2022.06.004 · Cited by 7
Exosomes-mediated drug delivery for the treatment of myocardial injury
Jiang, L., Lin, A., Jiang, R., Chen, P., Xu, C., & Hou, Y. (2023) · Annals of Medicine and Surgery · doi:10.1097/ms9.0000000000001473 · Cited by 8
Hu, S., Zhang, C., Ma, Q., Li, M., Yu, X., Zhang, H., Lv, S., Shi, Y., & He, X. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1438177 · Cited by 6
Cold Exposure Alleviates T2DM Through Plasma-Derived Extracellular Vesicles
Li, F., Xu, F., Li, C., Lei, L.-M., Shan, S., Zheng, M.-H., Lin, X., Guo, B., Tang, K.-X., Duan, J.-Y., et al. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s441847 · Cited by 7
Nasal administration of Xingnaojing biomimetic nanoparticles for the treatment of ischemic stroke
Li, N., Zhu, A., Chen, W., Li, J., Pan, L., Jiang, Y., Wang, X., Di, L., & Wang, R. (2024) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2024.124830 · Cited by 6
CircBTBD7-420aa Regulates the Progression of Atherosclerosis
Gan, X., Chi, B., Zhang, X., Ren, M., Bie, H., Jia, Q., Fu, Y., Li, C., Zhou, H., He, S., et al. (2024) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2024.09.003 · Cited by 6
Guo, L., Lv, N., Ji, J., Gao, C., Liu, S., Liu, Z., Lin, X., Liu, Z., & Wang, Y. (2025) · Acta Pharmacologica Sinica · doi:10.1038/s41401-025-01486-x · Cited by 6
Yao, X., Zhou, Y., Liu, Y., Jie, J., Wan, X., & Yang, P. (2025) · Advanced technology in neuroscience . · doi:10.4103/atn.atn-d-25-00009 · Cited by 7
Mirzaahmadi, B., Ahmadian, S., Haddadi, P., Nezhad‐Mokhtari, P., Nezamdoust, F. V., Yalameha, B., Chegeni, S. A., Rashidi, S., Mousakhani, A., Sokullu, E., et al. (2025) · Cell Communication and Signaling · doi:10.1186/s12964-025-02286-w · Cited by 10
M2 Macrophages‐Derived Exosomes Inhibited Podocyte Pyroptosis via lncRNA AFAP1 ‐ AS1 / EZH2 Axis
Zhan, Q., Liu, H., Zhao, M., & Huang, H. (2025) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.70056 · Cited by 6
Gene Therapy Approaches for Atherosclerosis Focusing on Targeting Lipid Metabolism and Inflammation
Bezsonov, E. E., Chernyi, N., Saruhanyan, M., Shimchenko, D., Bondar, N., Gavrilova, D., Baig, M. S., & Malogolovkin, A. S. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26146950 · Cited by 8
Yu, L., Luo, X., Zhang, Z., Li, X., Tian, M., Qian, J., Yang, J., Deng, R., Bai, X., Lu, C. C., et al. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.07.024 · Cited by 6
Liang, G.-B., Zeng, M., Wang, Q., Wang, W.-H., Liu, J., Gao, M., & He, Z. (2025) · Stem Cell Research & Therapy · doi:10.1186/s13287-025-04558-1 · Cited by 6
Li, X., Shen, Z., Zhang, S., Chen, Y., Lu, X., & Hu, X.-J. (2025) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2025.1664799 · Cited by 6
Wang, Y., Huang, J., An, Y., Li, Y., Chen, S., Mei, Y., Liu, D., & Tang, Q. (2025) · Stem Cell Research & Therapy · doi:10.1186/s13287-025-04598-7 · Cited by 6
Engineering Delivery Technologies for Optimizing mRNA Vaccines
Gu, T., Yan, X., & Liu, S. (2025) · ACS Nano Medicine · doi:10.1021/acsnanomed.5c00032 · Cited by 7
Research advances in enhancing wound healing through exosome-induced macrophage reprogramming
Wang, H., Wu, H., Han, Y., & Guo, L. (2025) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2025.152787 · Cited by 6
Kheirkhah, A. H., Sheykhhasan, M., Hosseinzadeh, F., & Fath-Bayati, L. (2025) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2025.102313 · Cited by 7
Zhao, X., Liu, D., Li, G., Xu, W., & Wu, G. (2026) · International Journal of Nanomedicine · doi:10.2147/ijn.s570411 · Cited by 6
Huang, H., Xu, W., Hao, X., Sun, P., Guo, M., Li, M., Liu, X., Peng, Y., Han, R., Tang, T., et al. (2026) · Journal of Controlled Release · doi:10.1016/j.jconrel.2026.114706 · Cited by 6
Artificial intelligence virtual extracellular vesicles (AIVEVs)
Liu, H., Li, S., Wang, J., & Su, J. H. (2026) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.12.050 · Cited by 10
Extracellular Vesicles in Drug Delivery: From Quality Assurance to Therapeutic Application
Zhang, K., & Fang, J. (2026) · International Journal of Nanomedicine · doi:10.2147/ijn.s579695 · Cited by 8
Zhang, M.-L., Li, Z., Pei, W., Li, X., Yang, H., Zhu, X., & Lu, K. (2023) · PubMed Central · doi:10.12122/j.issn.1673-4254.2023.03.08 · Cited by 5
Keysberg, C., Hertel, O., Hoffrogge, R., Reich, S., Hornung, N., Holzmann, K., & Otte, K. (2023) · Biotechnology and Bioengineering · doi:10.1002/bit.28612 · Cited by 7
Farahani, M. S., Hosseini‐Beheshti, E., Moazzeni, S. M., & Moghadam, M. F. (2023) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2023.130541 · Cited by 7
Li, W., Yang, Y., Lin, Y., & Mu, D. (2024) · Aesthetic Plastic Surgery · doi:10.1007/s00266-024-03861-1 · Cited by 6
Native and engineered extracellular vesicles: novel tools for treating liver disease
Jiang, S., Tian, S., Wang, P., Liu, J., Sun, K., Zhou, X., Han, Y., & Shang, Y. (2024) · Journal of Materials Chemistry B · doi:10.1039/d3tb01921g · Cited by 7
Extracellular vesicles in cancer: golden goose or Trojan horse
Han, T., Hao, Q., Chao, T., Sun, Q., Chen, Y., Gao, B., Guan, L., Ren, W., & Zhou, X. Y. (2024) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjae025 · Cited by 8
Tang, X., Ren, Y., Zeng, W., Feng, X., He, M., Lv, Y., Li, Y., & He, Y. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116979 · Cited by 6
Zhao, R., Han, F., Yu, Q., Zhu, Z., Tu, Z., Xia, T., & Li, B. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.03.007 · Cited by 6
Yuan, L., Ji, H., Cao, Y., Yi, H., Leng, Q., Zhou, J. H. S., & Mei, X. (2024) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1989 · Cited by 6
Yang, S., Zhu, H., Jin, H., Wang, K., Song, J., Sun, N., Liu, Y., Yin, X., Wang, R., Wu, X., et al. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123208 · Cited by 7
Xu, Y. X., Xu, L., Chen, Q., Zou, C., Huang, J., & Zhang, L. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1512480 · Cited by 9
Advances in the design and application of glycolysis-related nanodelivery systems for anti-tumor
Zhou, Y., Liu, M., Lü, N., Deng, X., Chen, X., Tang, L., Xie, Z., Lei, X., Yang, X., Zhou, S., et al. (2025) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2025.114844 · Cited by 6
Yang, J., Wu, S., & He, M. (2025) · Redox Biology · doi:10.1016/j.redox.2025.103806 · Cited by 6
RetractedResearch advances of extracellular vesicles in lung diseases
Wang, J., Shi, Y., Su, Y., Pang, C., Yang, Y., & Wang, W. (2025) · Cell Transplantation · doi:10.1177/09636897251362031 · Cited by 7
Exosomal microRNAs: potential targets for the prevention and treatment of diabetic cardiomyopathy
Zhang, T., Gao, Z., & Chen, K. (2022) · Journal of Cardiology · doi:10.1016/j.jjcc.2021.12.013 · Cited by 6
Design and development of novel fluorescence sensing material for exosome recognition
Hua, Q., Jin, Y. J., Wei, G., Wang, W., Wang, L., Yin, Y., Yang, J., Gu, Y., & Ni, C. (2022) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2022.112421 · Cited by 6
Barnwal, R. P., Kumar, S., Singh, G., Khera, A., Alajangi, H. K., & Khajuria, A. (2022) · Current Drug Delivery · doi:10.2174/1567201819666220404103936 · Cited by 6
Gao, Q., Qi, Z., Jin, X., Yang, Z., Yu, P., Yuan, X., Hu, Y., & Yang, X. (2022) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.15162 · Cited by 6
The Proteolytic Landscape of Ovarian Cancer: Applications in Nanomedicine
O’Connell, C., VandenHeuvel, S. N., Kamat, A. A., Raghavan, S. A., & Godin, B. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179981 · Cited by 6
Applications of engineered exosomes in drugging noncoding RNAs for cancer therapy
Alemi, F., Sadeghsoltani, F., Fattah, K., Hassanpour, P., Malakoti, F., Kardeh, S., Izadpanah, M., Zuccari, D. A. P. D. C., Yousefi, B., & Majidinia, M. (2023) · Chemical Biology & Drug Design · doi:10.1111/cbdd.14300 · Cited by 6
Emerging Roles of Small Extracellular Vesicles in Gastrointestinal Cancer Research and Therapy
Schneider, N., Hermann, P. C., Eiseler, T., & Seufferlein, T. T. W. (2024) · Cancers · doi:10.3390/cancers16030567 · Cited by 6
Drug Delivery for Neurological Disorders Using Nanotechnology
Nag, S., Bhatt, M., Ghosh, S., Dey, A., Paul, S., Dutta, S., Mohanto, S., Gowda, B. H. J., & Ahmed, M. G. (2023) · Springer eBooks · doi:10.1007/978-981-99-9510-3_7 · Cited by 6
Unveiling the hidden role of extracellular vesicles in brain metastases: a comprehensive review
Li, J., Lu, S., Chen, F., & Zhu, H. Q. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1388574 · Cited by 7
Wang, C., Li, H., Zhou, H., Xu, Y., Li, S., Zhu, M., Yu, B., & Feng, Y. (2024) · Aging · doi:10.18632/aging.205821 · Cited by 6
Liang, W., Luo, Y., Xu, A., Chu, J., Ji, W., Wang, L., Gu, Y., Lu, X., Hou, A., Liu, Y., et al. (2024) · Biomaterials Science · doi:10.1039/d4bm00878b · Cited by 7
Zou, Z., Wen, S., Yu, Q., Li, Y., An, J., Xiong, Y., Wu, Q., Tong, L., Wu, C., Mei, X., et al. (2023) · ACS Applied Nano Materials · doi:10.1021/acsanm.3c03712 · Cited by 5
Zeng, X., Liao, Y., Huang, D., Yang, H. J., Dai, Z., Chen, Z., Luo, X., Gong, H., Huang, S., & Zhang, L. (2025) · Scientific Reports · doi:10.1038/s41598-024-84689-2 · Cited by 5
Qiu, D., Yan, B., Xue, H., Xu, Z., Tan, G., & Liu, Y. (2025) · Experimental Cell Research · doi:10.1016/j.yexcr.2025.114457 · Cited by 6
Zhang, T., Jie, J., Liang, Y., Luo, J., Cheng, D., Qin, S., & Jiang, H. (2025) · Genomics · doi:10.1016/j.ygeno.2025.111043 · Cited by 5
Self-citationExosomes serve as molecular diagnostic biomarkers and carriers for tissue engineering applications
Zhang, Z., Cao, H., & Li, X. (2025) · Materials Today Communications · doi:10.1016/j.mtcomm.2025.112978 · Cited by 5
Peng, L., Chen, Y., Song, H., Shi, J., & Sun, K. (2025) · MedComm – Biomaterials and Applications · doi:10.1002/mba2.70016 · Cited by 5
Wang, Z., Yang, H.-S., Guo, H.-S., Li, Y.-Y., Zhong, J.-Y., Jiang, S., Li, J., Yang, Z.-Y., Zhou, C., Wang, J., et al. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1593827 · Cited by 5
Li, P., Xue, Y., & Gu, X. (2025) · Cancer Cell International · doi:10.1186/s12935-025-03889-6 · Cited by 5
Wang, W., Jiang, Y., Zhang, D., Zhang, X., Liang, Q. Y., Shi, J., Zhou, Y., & Zhou, F. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03588-4 · Cited by 6
Exosome in HBV infection: current concepts and future perspectives
Yuan, X., Huang, C., & Ran, Y. (2025) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1547525 · Cited by 5
Sun, R., Yang, Y., Zhang, B., Chen, J., Wang, Y., Jiang, Z., Zhang, L., Ashrafizadeh, M., Sethi, G., Shen, J., et al. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102267 · Cited by 5
Harnessing Regenerative Science in Aesthetic Surgery: The Biologically Driven Future
Olivas, C. G., Shauly, O., Hutchison, D. M., & Gould, D. J. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14176205 · Cited by 9
Chen, Q., Wang, W., He, X., Wang, C., Guo, H., & Ou, C. (2025) · Cancer Letters · doi:10.1016/j.canlet.2025.218034 · Cited by 7
Karthick, V., Thamarai, R., Amalraj, S., Suganya, M., & Suganya, P. (2025) · Journal of Molecular Histology · doi:10.1007/s10735-025-10631-z · Cited by 7
Cha, Z., Yu, L., Pu, J., Zhang, Y., Lu, Q., Huang, W., Li, T., & Lu, X. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2025.1645457 · Cited by 5
Recent advances in biomimetic nanodelivery systems for the treatment of osteoporosis
Ren, Z., Xiao, W., Yang, T., Han, Y., Bai, L., Feng, L., Guo, J., & Liu, S. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102373 · Cited by 6
Chen, J., Ma, Z., Wu, P., Qian, H., Su, L., Zhu, Z., & Wang, J. (2025) · Scientific Reports · doi:10.1038/s41598-025-23597-5 · Cited by 5
Wang, J. J., Ge, X., Lang, C., Xu, W., Hu, T., Wang, L., Hu, F., Sun, Y., Zhang, F., Cai, W., et al. (2025) · Science Advances · doi:10.1126/sciadv.adx7695 · Cited by 7
Metadata
- Authors
- Liang, Y., Duan, L., Lu, J., & Xia, J.
- Affiliations
- Chinese University of Hong Kong (HK)
- Shenzhen University Health Science Center (CN)
- Shenzhen KangNing Hospital (CN)
- Corresponding author
- Lu, Jianping
- Xia, Jiang
- Venue
- Theranostics
- Publisher
- Ivyspring International Publisher
- Published
- 2021
- Volume
- 11
- Issue
- 7
- Pages
- 3183-3195
- ISSN
- 1838-7640 (ISSN-L)
- PMC
- PMC7847680
- OpenAlex
- W3120452655
- Cited by
- 1,547
- References
- 97
- Citations by year
- 2026: 284 · 2025: 375 · 2024: 350 · 2023: 293 · 2022: 194 · 2021: 51
- FWCI
- 70.09
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Theranostics (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Extracellular vesicles in disease
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Interference and Gene Delivery
- Keywords
- exosomes, exosome engineering, targeted drug delivery, cell-free therapy, nanovesicles, nucleic acid delivery, small molecule delivery, immunogenicity, toxicity
- MeSH terms
- Animals, Humans, Membrane Proteins, Membranes, Protein Engineering, Drug Delivery Systems, Exosomes
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review