The DOI matches its Crossref record; 98 of the 98 references it cites were found in a registry or an index.
Engineering exosomes for targeted drug delivery
Open accessAbstract
Exosomes are cell-derived nanovesicles that are involved in the intercellular transportation of materials. Therapeutics, such as small molecules or nucleic acid drugs, can be incorporated into exosomes and then delivered to specific types of cells or tissues to realize targeted drug delivery. Targeted delivery increases the local concentration of therapeutics and minimizes side effects. Here, we present a detailed review of exosomes engineering through genetic and chemical methods for targeted drug delivery. Although still in its infancy, exosome-mediated drug delivery boasts low toxicity, low immunogenicity, and high engineerability, and holds promise for cell-free therapies for a wide range of diseases.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Two main approaches can be used to enhance the targeting ability of exosomes for specific applications: direct modification of exosomes by chemical means or, indirect manipulation of the donor cells through genetic engineering techniques [89, 103, 118–120]”
From Exosome for mRNA delivery: Strategies and therapeutic applications (2024) · cites this paper as [119]
In the citing paper
“Unlike synthetic nanocarriers such as liposomes or polymer-based systems, exosomes are less likely to trigger adverse reactions, making them a safer option for therapeutic applications [26].”
From Emerging role of exosomes in cancer therapy: progress and challenges (2025) · cites this paper as [26]
In the citing paper
“Exosomes can deliver small molecules to targeted cells or tissues for targeted therapy and improve therapy accuracy and efficacy [26].”
From Emerging role of exosomes in cancer therapy: progress and challenges (2025) · cites this paper as [26]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
1 retracted
Rana, S., Yue, S., Stadel, D., & Zöller, M. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2012.06.018 · Cited by 688
RetractedThéry, C., Witwer, K. W., Aikawa, E., Alcaraz, M. J., Anderson, J. D., Andriantsitohaina, R., Antoniou, A., Arab, T., Archer, F., Atkin‐Smith, G. K., et al. (2018) · Journal of Extracellular Vesicles · doi:10.1080/20013078.2018.1535750 · Cited by 11,099
The biology , function , and biomedical applications of exosomes
Kalluri, R., & LeBleu, V. S. (2020) · Science · doi:10.1126/science.aau6977 · Cited by 10,770
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
Alvarez-Erviti, L., Seow, Y., Yin, H., Betts, C., Lakhal, S., & Wood, M. J. A. (2011) · Nature Biotechnology · doi:10.1038/nbt.1807 · Cited by 4,930
Mathieu, M., Jaular, L. M., Lavieu, G., & Théry, C. (2018) · Nature Cell Biology · doi:10.1038/s41556-018-0250-9 · Cited by 3,863
Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
Trajković, K., Hsu, C., Chiantia, S., Rajendran, L., Wenzel, D., Wieland, F., Schwille, P., Brügger, B., & Simons, M. (2008) · Science · doi:10.1126/science.1153124 · Cited by 3,760
Reassessment of exosome composition
Jeppesen, D. K., Fenix, A. M., Franklin, J. L., Higginbotham, J. N., Zhang, Q., Zimmerman, L. J., Liebler, D. C., Ping, J., Liu, Q., Evans, R., et al. (2019) · Cell · doi:10.1016/j.cell.2019.02.029 · Cited by 2,975
Johnstone, R. M., Adam, M., Hammond, J. R., Orr, L., & Turbide, C. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)48095-7 · Cited by 2,931
Routes and mechanisms of extracellular vesicle uptake
Mulcahy, L. A., Pink, R. C., & Carter, D. R. F. (2014) · Journal of Extracellular Vesicles · doi:10.3402/jev.v3.24641 · Cited by 2,832
Identification and proteomic profiling of exosomes in human urine
Pisitkun, T., Shen, R., & Knepper, M. A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403453101 · Cited by 2,162
Flagged first, then by citations
Cited by
Sorted by citations
Items 701–800 of 1,000
Advances of exosomal miRNAs in the diagnosis and treatment of ovarian cancer
Xiong, J., Fu, F., Feng, Y. Y., & He, X.-J. (2023) · Discover Oncology · doi:10.1007/s12672-023-00674-7 · Cited by 15
The miR-183 Cluster: Biogenesis, Functions, and Cell Communication via Exosomes in Cancer
Li, S., Wei, M., Guo, Z., Liu, M., He, Y., Li, Y., & Ma, Z. (2023) · Cells · doi:10.3390/cells12091315 · Cited by 13
Song, X., Zhang, C., Xing, M., He, C., Wang, D., Chong, L., Zhang, X., Chen, M., & Li, J. (2023) · Journal of Materials Chemistry B · doi:10.1039/d3tb00595j · Cited by 13
Lv, Z., Fu, K., & Zhang, Q. (2023) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2023.113429 · Cited by 13
Engineered multitargeting exosomes carrying miR-323a-3p for CRC therapy
Pang, Y., Chen, X., Xu, B., Zhang, Y., Liang, S., Hu, J., Liu, R., Luo, X., & Wang, Y. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.125794 · Cited by 13
Role of exosomes in metastasis and therapeutic resistance in esophageal cancer
Ning, X.-Y., Ma, J., He, W., & Ma, J. (2023) · World Journal of Gastroenterology · doi:10.3748/wjg.v29.i42.5699 · Cited by 14
Advances of nanoparticle-mediated diagnostic and theranostic strategies for atherosclerosis
Lin, L., Chen, L., Yan, J., Chen, P., Du, J., Zhu, J., Yang, X., Geng, B., Li, L., & Zeng, W. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1268428 · Cited by 13
Zhang, Y., Sun, M., Zhao, H., Wang, Z., Shi, Y., Dong, J., Wang, K., Wang, X., Li, X., Qi, H., et al. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s439728 · Cited by 13
Hao, C., Ma, S., Yang, Y., & Wang, C. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics16010006 · Cited by 14
The landscape of extracellular vesicles combined with intranasal delivery towards brain diseases
Li, J., Zhang, H., Jiang, Y., Li, N., Zhu, A., Zhang, Y., Feng, K., Zeng, W., Di, L., & Wang, R. (2024) · Nano Today · doi:10.1016/j.nantod.2024.102169 · Cited by 15
Khoushab, S., Aghmiuni, M. H., Esfandiari, N., Sarvandani, M. R. R., Rashidi, M., Taheriazam, A., Entezari, M., & Hashemi, M. (2024) · Pathology - Research and Practice · doi:10.1016/j.prp.2024.155214 · Cited by 14
Folic acid‐decorated astrocytes‐derived exosomes enhanced the effect of temozolomide against glioma
Liu, H., & Zhang, Y. (2024) · The Kaohsiung Journal of Medical Sciences · doi:10.1002/kjm2.12819 · Cited by 13
Engineering Phaeodactylum tricornutum exosomes to enhance intracellular fucoxanthin delivery
Tian, F., Liu, J., Wang, P., Xu, R., & Cai, L. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.104164 · Cited by 13
Hua, X., Liu, Y., Liu, X., Zhu, Q., Zhou, S., Li, Q., & Liu, S. (2024) · Biomedical Analysis · doi:10.1016/j.bioana.2024.05.002 · Cited by 13
Dual anti-angiogenic and anti-inflammatory action of tRNA-Cys-5-0007 in ocular vascular disease
Ma, Y., Zhang, Y., Zhang, H., Zhao, Y., Li, X., Jiang, Y., Yao, M., Jiang, Q. L., & Yan, B. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-05338-w · Cited by 13
Anti-BCMA–engineered exosomes for bortezomib-targeted delivery in multiple myeloma
Yuan, S., Li, Q., He, C., Bing, M., Zhang, X., Xu, H. P., Wang, Z., Zhao, M., Zhang, Y., Chai, Y., et al. (2024) · Blood Advances · doi:10.1182/bloodadvances.2023012464 · Cited by 14
Role of Exosomes in Cardiovascular Diseases
Lin, Q., He, P., Tao, J., & Peng, J. (2024) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2506222 · Cited by 14
Li, L., Wang, N., Li, X., Zhang, Z., Zhu, Z., Zhuo, Y., Jiang, X., Wang, J., Guo, C., Guo, C., et al. (2024) · Nano Today · doi:10.1016/j.nantod.2024.102377 · Cited by 13
Shao, M., Rodrigues, J. D. S., Sousa‐Oliveira, I., Moradialvand, M., Asadollahi, P., Veiga, F., Hameed, H., Jha, N. K., Sillanpää, M. E. T., Sethi, G., et al. (2024) · Applied Materials Today · doi:10.1016/j.apmt.2024.102395 · Cited by 13
Chitosan–exosome synergy: Advanced cell-free scaffold approaches for bone tissue engineering
Suresh, N., Shanmugavadivu, A., & Selvamurugan, N. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.140753 · Cited by 15
Exosome technology: A novel and effective drug delivery system in the field of cancer therapy
Geng, J.-X., Lu, Y.-F., Zhou, J.-N., Huang, B., & Qin, Y. (2025) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v17.i3.101857 · Cited by 13
Li, T., Zhao, J., Yuan, J., Ding, R., Yang, G., Cao, J., Zhao, X., Liu, J., Liu, Y., Xu, P., et al. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.101648 · Cited by 13
Anticancer potential of lactoferrin: effects, drug synergy and molecular interactions
León-Flores, D. B., Siañez-Estrada, L. I., Iglesias-Figueroa, B. F., Siqueiros-Cendón, T., Espinoza-Sánchez, E. A., Varela-Ramı́rez, A., Aguilera, R. J., & Rascón-Cruz, Q. (2025) · BioMetals · doi:10.1007/s10534-025-00672-y · Cited by 13
Wu, P., Wang, Z., Sun, Y., Cheng, Z., Wang, M., & Wang, B. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03297-y · Cited by 14
Raza, M. A., Khatoon, N., Parveen, R., Nirisha, V., Thakur, Y., Thakur, Y., Lata, K. A., Shifana, A. S., Disouza, J., Saoji, S. D., et al. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.145145 · Cited by 14
Exosomes promise better bone regeneration
Hu, S., Wang, S., Yang, X., Li, P., Li, Z., Luo, B., Liang, Y., & Pan, X. (2025) · Regenerative Therapy · doi:10.1016/j.reth.2025.06.020 · Cited by 16
Self-citationExtracellular vesicles derived from macrophages: Current applications and prospects in tumors
Lou, K., Feng, S., Luo, H., Zou, J., Zhang, G., & Zou, X. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.1097074 · Cited by 15
Novel Development of Nanoparticles—A Promising Direction for Precise Tumor Management
Zhang, D., Tang, Q., Chen, J., Wei, Y., & Chen, J. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics15010024 · Cited by 14
Zhang, W., Wang, J., Ngo, C. H. L., Li, L., & Wang, Y. (2025) · Advanced NanoBiomed Research · doi:10.1002/anbr.202500008 · Cited by 12
Mu, Y., Luo, R., Zhao, L., Chen, D., Cao, L., Jin, Z., Li, K., & Wang, M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26115323 · Cited by 12
Latest developments in photosensitizers: improving stability, specificity and responsiveness
Dong, J., Tang, J., Li, X., Zeng, Y., Su, X., He, Y., & Liu, X. (2025) · Future Medicinal Chemistry · doi:10.1080/17568919.2025.2515813 · Cited by 12
ECHS1: pathogenic mechanisms, experimental models, and emerging therapeutic strategies
Fu, Q., Qiu, R., Li, S., Qin, Y., Lu, Z., Liyao, S., Yang, Z., Cheng, X., Chen, Y., Xu, H., et al. (2025) · Orphanet Journal of Rare Diseases · doi:10.1186/s13023-025-03959-y · Cited by 13
Voros, C., Papadimas, G. K., Mavrogianni, D., Koulakmanidis, A.-M., Athanasiou, D., Bananis, K., Athanasiou, A. I., Athanasiou, A. V., Papapanagiotou, I., Vaitsis, D., et al. (2025) · Genes · doi:10.3390/genes16091101 · Cited by 13
Adipose-derived stem cell exosomes: emerging roles and therapeutic application
Gong, Y., Ma, H., Zheng, Z., Wang, X., Zhang, J., & Zhao, X. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1637342 · Cited by 13
Dayanandan, A. P., Bello, A. B., Arai, Y., Lee, S. J., & Lee, S.-H. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.09.042 · Cited by 18
Zeng, F., Zhao, C., Wang, R., Ren, L., Qiu, H., Zou, Z., Ding, H., Sun, Z., Li, J., & Dong, S. (2022) · Genes & Diseases · doi:10.1016/j.gendis.2022.06.007 · Cited by 12
Samarpita, S., & Li, X. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087647 · Cited by 12
The role of extracellular vesicle-derived miRNAs in adipose tissue function and metabolic health
Paneru, B., & Hill, D. A. (2023) · Immunometabolism · doi:10.1097/in9.0000000000000027 · Cited by 17
Li, X., He, S., Luo, B., Li, P., Chen, X., Wu, M., Song, C. Q., Liu, C., Yang, T., Zhang, X., et al. (2023) · Small · doi:10.1002/smll.202303541 · Cited by 12
Cheng, Z., Shang, J., Wang, H., Yu, L., Zhu, Y., Zhang, Y., Du, Y., & Tian, J. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.08.040 · Cited by 12
Interaction of Macrophages with Bone Healing Microenvironment: Mechanism and Biomaterials
Lu, X., Gao, J., Bao, W., Xu, J., Sun, X., Wang, Y., & Li, B. (2023) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2023.0157 · Cited by 13
Role of dendritic cell‑derived exosomes in allergic rhinitis (Review)
Kang, C., He, H., Liu, P., Liu, Y., Li, X., Zhang, J., Hong, R., Zeng, X., Zhao, H., Liu, J., et al. (2023) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2023.5320 · Cited by 13
Yin, X., Lin, L., Fang, F., Zhang, B., & Shen, C. (2023) · Stem Cells International · doi:10.1155/2023/6500831 · Cited by 13
Wang, X., Li, H., Wang, Z., Chen, J., Chen, W., Zhou, X., Zhang, L., Xu, S., Gao, X., & Yang, G. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c06439 · Cited by 12
Sahoo, R. K., Tripathi, S. K., Biswal, S., Panda, M., Mathapati, S., & Biswal, B. K. (2024) · Biotechnology Journal · doi:10.1002/biot.202300370 · Cited by 12
Exosomes—Promising Carriers for Regulatory Therapy in Oncology
Jóźwicka, T. M., Erdmańska, P. M., Stachowicz-Karpińska, A., Olkiewicz, M., & Jóźwicki, W. (2024) · Cancers · doi:10.3390/cancers16050923 · Cited by 13
Construction of exosome-loaded LL-37 and its protection against zika virus infection
Wang, C., Li, M., Xia, X., Fu, Y., Wang, Y., Xu, W., Wei, H., & Wei, L. (2024) · Antiviral Research · doi:10.1016/j.antiviral.2024.105855 · Cited by 12
Xu, Y., Ma, L., Wang, Y., & Shi, C. (2024) · Chinese Chemical Letters · doi:10.1016/j.cclet.2024.109766 · Cited by 12
Chen, A., Zhang, W., Jiang, C., Jiang, Z., & Tang, D. (2024) · International Journal of Cancer · doi:10.1002/ijc.34934 · Cited by 12
Ye, X., Liu, Y., Chen, C., Sun, Y., Li, F., Fu, Y., Luo, J., Su, L., & Chi, W. (2024) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2024.102209 · Cited by 13
Signature of click chemistry in exosome modification for cancer therapeutic
Mukerjee, N., & Sonar, S. (2024) · Clinical and Translational Discovery · doi:10.1002/ctd2.335 · Cited by 13
Current concepts of the crosstalk between lncRNA and E2F1: shedding light on the cancer therapy
Huang, P., Wen, F., & Li, Q. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1432490 · Cited by 12
Exosomes: Emerging Insights into the Progression of Pancreatic Cancer
Zhou, X., Yan, Y., Shen, Y., Xu, M., & Xu, W. (2024) · International Journal of Biological Sciences · doi:10.7150/ijbs.97076 · Cited by 12
Zhang, H., Xia, J., Wang, X., Wang, Y., Chen, J., He, L., & Dai, J. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s479697 · Cited by 13
Self-citationZhou, X. M., Jaiswal, M., Shi, J., Guo, J., Kundu, S., Guo, Z., & Zeng, Y. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c20294 · Cited by 14
The Application of Stem Cells and Exosomes in Promoting Nerve Conduits for Peripheral Nerve Repair
Li, M., Tang, Y., Zhou, C., Geng, Y., Zhang, C., Hsu, Y.-W., Ma, L., Guo, W., Li, M., & Wang, Y. (2025) · Biomaterials Research · doi:10.34133/bmr.0160 · Cited by 14
Wei, D., Li, F., Guo, C., Chen, J., & You, Y. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1601843 · Cited by 14
Chen, Y., Wang, X., Li, H., Zhang, Z., Gao, Y., Ge, L., Xin, L., Gao, X., Shi, L., Hao, J., et al. (2025) · Cancer Letters · doi:10.1016/j.canlet.2025.218037 · Cited by 11
Biomaterials in personalized drug delivery: innovations, challenges, and future directions
Hrapović, A., Islam, N., Bourghli, A. A., Sezer, A., Kovalenko, B., Lokvančić, H., Adilović, M., Šutković, J., Hromić-Jahjefendić, A., & Uversky, V. N. (2026) · PeerJ · doi:10.7717/peerj.20982 · Cited by 13
The promising roles of exosomal microRNAs in osteosarcoma: A new insight into the clinical therapy
Tian, W., Niu, X., Feng, F., Wang, X., Wang, J., Yao, W., & Zhang, P. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114771 · Cited by 12
Therapeutic Benefits of Stem Cells and Exosomes for Sulfur-Mustard-Induced Tissue Damage
Bosholm, C. C., Zhu, H., Yu, P., Cheng, K., Murphy, S. V., McNutt, P. M., & Zhang, Y. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24129947 · Cited by 11
Csöbönyeiová, M., Smolinská, V., Harsányi, Š., Ivantysyn, M., & Klein, M. (2023) · Biomedicines · doi:10.3390/biomedicines11061736 · Cited by 11
Recent engineering advances of EVs for compounds, nucleic acids, and TCM delivery
Di, Y., Wang, W., Wang, Y., & Wang, J. (2023) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2023.106584 · Cited by 12
Zhang, C., Jiang, T., Jiang, G., Xu, X., Yan, C., Kang, Y., Xiang, X., Liu, S., Nie, P., Zhang, M., et al. (2023) · The FASEB Journal · doi:10.1096/fj.202301549r · Cited by 11
Immunotherapy of M2 macrophage derived from exosome-based nanoparticles for spinal cord injury
Bai, L., Gao, J., Zhang, P., Lin, S., & Zhang, C. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.111983 · Cited by 11
Exosomes as mediators of signal transmitters in biotoxins toxicity: a comprehensive review
Xu, T., Huangfu, B., He, X., & Huang, K. (2024) · Cell Biology and Toxicology · doi:10.1007/s10565-024-09867-4 · Cited by 12
Mitigation of Oxidative Stress in Idiopathic Pulmonary Fibrosis Through Exosome-Mediated Therapies
Wang, Z., Zhang, Y., & Li, X. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s453739 · Cited by 13
Qiu, J., Jiang, Y., Ye, N., Jin, G., Shi, H., & Qian, D. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-05531-x · Cited by 13
Zheng, L. T., Chang, R., Liang, B., Wang, Y., Zhu, Y., Jia, Z., Fan, J., Zhang, Z., Du, B., & Kong, D. (2024) · Cancer Drug Resistance · doi:10.20517/cdr.2024.107 · Cited by 11
Wang, M., Chen, D., Pan, R., Sun, Y., He, X., Qiu, Y.-Y., Hu, Y., Wu, X., Xi, X., Hu, R., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1548206 · Cited by 11
Cai, M., Tian, F., Han, J., Wang, L., Hu, S., Dong, P., Qiao, W., Zhang, H., Wang, Y., Chen, H., et al. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.113886 · Cited by 11
Prospects of engineered exosomes in clinical applications: a review
Li, Y., Meng, D., Cheng, Y., Sun, Y., Dong, Y., Shi, J., Wan, G., & Deng, C. (2025) · Drug Development and Industrial Pharmacy · doi:10.1080/03639045.2025.2541789 · Cited by 11
Exosome-Based Theranostics for Liver Diseases
Luo, N., Li, J., Dong, R., & Lu, J. (2022) · Disease Markers · doi:10.1155/2022/7888906 · Cited by 11
Self-citationBian, X., Li, B., Tang, H., Li, Q., Hu, W., Qian, W., Ma, K., Yang, Y., Li, H., Fu, X., et al. (2022) · Frontiers in Surgery · doi:10.3389/fsurg.2022.1065172 · Cited by 11
microRNAs ‐based diagnostic and therapeutic applications in liver fibrosis
Zhao, X., Xue, X., Cui, Z., Amevor, F. K., Wan, Y., Fu, K., Wang, C., Peng, C. Y., & Li, Y. (2022) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1773 · Cited by 12
Chen, L., Zhang, N., Huang, Y., Zhang, Q., Fang, Y., Fu, J., Yuan, Y., Chen, L., Chen, X., Xu, Z., et al. (2023) · Stem Cell Reviews and Reports · doi:10.1007/s12015-023-10583-5 · Cited by 11
Exosomes: potential diagnostic markers and drug carriers for adenomyosis
Cheng, W.-X., Wei, S., Zhou, Y., Shao, Y., & Li, M.-Y. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1216149 · Cited by 11
Polarized Macrophages and Their Exosomes: Implications for Autoimmune and Immune-Mediated Diseases
Yuan, G. (2025) · Biology · doi:10.3390/biology14101371 · Cited by 12
Extracellular vesicles in laboratory medicine: a review and outlook
Wang, X., Liu, M., Zhao, M., Shen, H., Jin, Q., Rao, D., & Huang, D. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1709461 · Cited by 10
The Immune Microenvironment in Liver Cancer: From Analysis to Targeting
Lan, J., Li, H., Xue, J., Duan, Y., Sun, J., & Niu, M. (2025) · Advanced Science · doi:10.1002/advs.202518487 · Cited by 10
Advances in Intranasal Delivery of Exosomes for Central Nervous System Disorders
Arjmand, B., Mojavezi, A. R., Kamroo, A., Yazdi, R. K., Rezaei–Tavirani, M., & Vahedi, M.-S. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05563-4 · Cited by 12
Lung-targeted RNA delivery systems: strategies and therapeutic applications
Xu, S., Li, M., Wang, T., Chen, R., Zhou, M., Tang, Z., Liu, Q., Hu, L., & Li, Z. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-04019-0 · Cited by 15
Wang, Y., Hu, M., Spanos, M., Xu, S., Song, J., Li, G., Crețoiu, D., & Xiao, J. (2026) · 中国科学通报:英文版 · doi:10.1016/j.scib.2026.01.067 · Cited by 10
Chuang, Y.-T., Shiau, J., Tang, J., Farooqı, A. A., Chang, F., Tsai, Y., Yen, C., & Chang, H. (2023) · Cancers · doi:10.3390/cancers15082215 · Cited by 9
Tang, J.-Y., Chuang, Y.-T., Shiau, J., Yen, C., Chang, F., Tsai, Y., Farooqı, A. A., & Chang, H. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241512449 · Cited by 11
Mesenchymal Stem Cells Applications in Alzheimer's Disease
Oyebode, O. D., & Tulay, P. (2023) · Global Medical Genetics · doi:10.1055/s-0043-1777087 · Cited by 11
Moradi, A., Shirangi, A., Asadi, M., Farokhi, M., Gholami, M., Aminianfar, H., Atyabi, F., Mottaghitalab, F., & Dinarvand, R. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.105313 · Cited by 11
Bioinspired and biomimetic strategies for inflammatory bowel disease therapy
Zhang, L., Ye, P., Zhu, H., Zhu, L., Ren, Y., & Lei, J. (2024) · Journal of Materials Chemistry B · doi:10.1039/d3tb02995f · Cited by 10
Guo, M., Sun, C., Liu, R., Jiang, J., Qian, Y., Yang, Y., Sun, Q., Dong, Y., Zhao, Y. J., & Liu, Y. (2024) · SmartMat · doi:10.1002/smm2.1279 · Cited by 10
Zhang, C., Li, D., Wang, Z., Wang, D., Lu, Y., Zhang, K., Yuan, Y., Mei, X., & Chen, S. (2024) · Materials & Design · doi:10.1016/j.matdes.2024.112844 · Cited by 10
Adipose exosomal noncoding RNAs: Roles and mechanisms in metabolic diseases
Wu, Y., Lin, Z., Li, C., Lin, X., Shan, S., Guo, B., Zheng, M., Wang, Y., Li, F., & Yuan, L. (2024) · Obesity Reviews · doi:10.1111/obr.13740 · Cited by 12
Bi, W., Mu, X., Li, Y., Sun, Q., Xiang, L., Hu, M., & Liu, H. (2024) · Human Cell · doi:10.1007/s13577-024-01086-7 · Cited by 11
Engineered exosomes: a potential therapeutic strategy for septic cardiomyopathy
Mao, L., Liu, S., Chen, Y., Huang, H., Ding, F., & Deng, L. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1399738 · Cited by 11
Wu, Y., Shan, X., Zhang, Y., Shi, W., Zhu, X., Yu, M., Xie, S., Guo, L., Chen, Z., Zhang, C., et al. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.154653 · Cited by 10
Luan, X., Wang, X., Bian, G., Li, X., Gao, Z., Liu, Z., Zhang, Z., Han, T., Zhao, J., Zhao, H., et al. (2024) · Oncology Reports · doi:10.3892/or.2024.8846 · Cited by 10
Wu, T., Song, H., Wang, R., Wang, W., & Xing, J. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.139363 · Cited by 10
Mesenchymal stromal cell exosomes for drug delivery of prostate cancer treatments: a review
Wang, C., Feng, Y., Rong, X., Yan, J., Lv, B., Jiang, H., Duan, L., & Jiang, J. (2025) · Stem Cell Research & Therapy · doi:10.1186/s13287-025-04133-8 · Cited by 12
Self-citationZhao, J., Fang, W. Y., Gao, Y., Chen, J., Wang, G., & Gu, J. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1531425 · Cited by 10
Tan, W., Ma, L., Li, Y., Zhang, Y., Hu, Z., Li, W., Ding, H., Liu, X., Xie, L., Deng, C., et al. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.156694 · Cited by 10
The Roles of Exosomes in Anti‐Cancer Drugs
Feng, P., Zhang, X., Gao, J., Jiang, L., & Li, Y. (2025) · Cancer Medicine · doi:10.1002/cam4.70897 · Cited by 11
Metadata
- Authors
- Liang, Y., Duan, L., Lu, J., & Xia, J.
- Affiliations
- Chinese University of Hong Kong (HK)
- Shenzhen University Health Science Center (CN)
- Shenzhen KangNing Hospital (CN)
- Corresponding author
- Lu, Jianping
- Xia, Jiang
- Venue
- Theranostics
- Publisher
- Ivyspring International Publisher
- Published
- 2021
- Volume
- 11
- Issue
- 7
- Pages
- 3183-3195
- ISSN
- 1838-7640 (ISSN-L)
- PMC
- PMC7847680
- OpenAlex
- W3120452655
- Cited by
- 1,547
- References
- 97
- Citations by year
- 2026: 284 · 2025: 375 · 2024: 350 · 2023: 293 · 2022: 194 · 2021: 51
- FWCI
- 70.09
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Theranostics (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Extracellular vesicles in disease
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Interference and Gene Delivery
- Keywords
- exosomes, exosome engineering, targeted drug delivery, cell-free therapy, nanovesicles, nucleic acid delivery, small molecule delivery, immunogenicity, toxicity
- MeSH terms
- Animals, Humans, Membrane Proteins, Membranes, Protein Engineering, Drug Delivery Systems, Exosomes
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review