A neural mechanism of speed-accuracy tradeoff in macaque area LIP
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Decision making often involves a tradeoff between speed and accuracy. Previous studies indicate that neural activity in the lateral intraparietal area (LIP) represents the gradual accumulation of evidence toward a threshold level, or evidence bound, which terminates the decision process. The level of this bound is hypothesized to mediate the speed-accuracy tradeoff. To test this, we recorded from LIP while monkeys performed a motion discrimination task in two speed-accuracy regimes. Surprisingly, the terminating threshold levels of neural activity were similar in both regimes. However, neurons recorded in the faster regime exhibited stronger evidence-independent activation from the beginning of decision formation, effectively reducing the evidence-dependent neural modulation needed for choice commitment. Our results suggest that control of speed vs accuracy may be exerted through changes in decision-related neural activity itself rather than through changes in the threshold applied to such neural activity to terminate a decision.
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The factors that determine when to stop gathering information and commit to a final decision, as well as which options to sample from, remain an active area of investigation.
“the factors that determine when to stop gathering information and commit to a final decision, as well as which options to sample from, remain an active area of investigation1,4,9–11.”
From Interpretable abstractions of artificial neural networks predict behavior and neural activity during human information gathering (2026) · cites this paper as [9]
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- Authors
- Hanks, T., Kiani, R., & Shadlen, M. N.
- Affiliations
- Princeton University (US)
- New York University (US)
- Howard Hughes Medical Institute (US)
- Corresponding author
- Hanks, Timothy
- Shadlen, Michael N
- Venue
- eLife
- Publisher
- eLife Sciences Publications, Ltd
- Published
- 2014-05-27
- Volume
- 3
- ISSN
- 2050-084X (ISSN-L)
- PMC
- PMC4054775
- OpenAlex
- W2170716773
- Cited by
- 222
- References
- 56
- Citations by year
- 2026: 13 · 2025: 19 · 2024: 13 · 2023: 22 · 2022: 14 · 2021: 20 · 2020: 21 · 2019: 19 · 2018: 26 · 2017: 14 · 2016: 23 · 2015: 15 · 2014: 3
- FWCI
- 10.23
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- eLife (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- eScholarship (California Digital Library) (submittedVersion, cc-by)
- Funders
- Howard Hughes Medical Institute
- National Eye Institute (EY11378)
- Human Frontier Science Program (RGP0067/2011)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- speed-accuracy trade-off, lateral intraparietal area, decision-making, evidence accumulation, decision threshold, motion discrimination, macaque
- MeSH terms
- Animals, Bayes Theorem, Behavior, Animal, Choice Behavior, Decision Making, Macaca, Models, Neurological, Motion Perception, Neurons, Neurophysiology, Photic Stimulation, Reaction Time, Time Factors, Reproducibility of Results
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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