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Cited by 601Neuroscience and Music PerceptionMultisensory perception and integrationNeural dynamics and brain function

Representation of Time by Neurons in the Posterior Parietal Cortex of the Macaque

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Leon, Matthew I, Shadlen, Michael N·2003·Neuron
DOI 10.1016/s0896-6273(03)00185-5
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Abstract

The neural basis of time perception is unknown. Here we show that neurons in the posterior parietal cortex (area LIP) represent elapsed time relative to a remembered duration. We trained rhesus monkeys to report whether the duration of a test light was longer or shorter than a remembered "standard" (316 or 800 ms) by making an eye movement to one of two choice targets. While timing the test light, the responses of LIP neurons signaled changes in the monkey's perception of elapsed time. The variability of the neural responses explained the monkey's uncertainty about its temporal judgments. Thus, in addition to their role in spatial processing and sensorimotor integration, posterior parietal neurons encode signals related to the perception of time.

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Crossref · 10.1016/s0896-6273(03)00185-5

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63 of 63 references verified0 citation errors · 0 not checkable

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  • The dip in firing rate seems to mark the beginning of evidence accumulation.

    “The dip, observed in other studies 2,12–14, seems to mark the beginning of evidence accumulation.”

    From Decision-making with multiple alternatives (2008) · cites this paper as [12]

  • A time-dependent rise of firing rate in LIP and elsewhere has been interpreted as a representation of elapsed time in the form of a hazard rate or anticipation function.

    “A time-dependent rise of firing rate in LIP and elsewhere has been interpreted as a representation of elapsed time in the form of a hazard rate or anticipation function 12,33–35.”

    From Decision-making with multiple alternatives (2008) · cites this paper as [12]

  • Previous studies have shown that LIP responses are modulated by many factors, such as attention, expectation, time, motor intention, experienced value, reward, and the prior probability of making an eye movement.

    “In addition, previous studies have shown that LIP responses are modulated by many factors, such as attention, expectation, time, motor intention, experienced value, reward, and the prior probability of making an eye movement12,13,39–42.”

    From Microstimulation of macaque area LIP affects decision-making in a motion discrimination task (2006) · cites this paper as [40]

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Authors
Leon, M. I., & Shadlen, M. N.
Affiliations
Howard Hughes Medical Institute (US)
Corresponding author
Shadlen, Michael N
ORCID
Shadlen, Michael N
Venue
Neuron
Publisher
Elsevier BV
Published
2003-04
Volume
38
Issue
2
Pages
317-327
ISSN
0896-6273 (ISSN-L)
DOI
10.1016/s0896-6273(03)00185-5
OpenAlex
W1983315064
Semantic Scholar
a043b2c8b97735bd36660238ce36645ba6d964df
Cited by
601
References
63
Citations by year
2026: 9 · 2025: 13 · 2024: 13 · 2023: 15 · 2022: 23 · 2021: 16 · 2020: 18 · 2019: 38 · 2018: 20 · 2017: 33 · 2016: 25 · 2015: 26 · 2014: 41 · 2013: 34 · 2012: 28
FWCI
12.38
Type
journal article
Language
en
Open access
Licence
Locations
  • Neuron (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Multisensory perception and integration
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Keywords
time perception, posterior parietal cortex, lateral intraparietal area, duration memory, temporal judgment, rhesus monkeys, neural variability, temporal uncertainty, eye movements
MeSH terms
Action Potentials, Animals, Choice Behavior, Cues, Discrimination Learning, Electrodes, Implanted, Eye Movements, Female, Fixation, Ocular, Macaca mulatta, Neurons, Parietal Lobe, Photic Stimulation, Time Perception

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