Neural activity in a hippocampus-like region of the teleost pallium is associated with active sensing and navigation
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Abstract
Most vertebrates use active sensing strategies for perception, cognition and control of motor activity. These strategies include directed body/sensor movements or increases in discrete sensory sampling events. The weakly electric fish, Gymnotus sp., uses its active electric sense during navigation in the dark. Electric organ discharge rate undergoes transient increases during navigation to increase electrosensory sampling. Gymnotus also use stereotyped backward swimming as an important form of active sensing that brings objects toward the electroreceptor dense fovea-like head region. We wirelessly recorded neural activity from the pallium of freely swimming Gymnotus. Spiking activity was sparse and occurred only during swimming. Notably, most units tended to fire during backward swims and their activity was on average coupled to increases in sensory sampling. Our results provide the first characterization of neural activity in a hippocampal (CA3)-like region of a teleost fish brain and connects it to active sensing of spatial environmental features.
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Cells fundamental to spatial cognition in mammals-for example, place cells-have yet to be established in any fish species.
“cells fundamental to spatial cognition in mammals—for example, place cells (PCs)5,6—have yet to be established in any fish species”
From A population code for spatial representation in the zebrafish telencephalon (2024) · cites this paper as [23]
The Discussion says that classic mammalian-like spatially tuned neurons may not yet have been sampled in the teleost pallium, and that the recorded DDi cells are not exact matches for place cells. This supports the narrower point that place cells were not established in the teleosts discussed, but the paper does not establish the claim for every fish species. (LLM, conf=0.83)
Experimental — accuracy not yet measuredExperimental studies using well-controlled behavioral procedures combined with brain lesion, neural activity recording, and neuro-morphofunctional techniques have provided evidence on the critical role of the teleost fish hippocampal pallium in spatial cognition.
“A growing number of experimental studies using well-controlled behavioral procedures combined with brain lesion, neural activity recording, and neuro-morphofunctional techniques have provided evidence on the critical role of the teleost fish hippocampal pallium in spatial cognition [28,112,157,180,181,182,183,184,185,186].”
From Spatial Cognition in Teleost Fish: Strategies and Mechanisms (2021) · cites this paper as [28]
Fotowat et al. and Trinh et al. found cells in the hippocampal pallium of an electrosensory gymnotiform that exhibit spatial navigation-related activity.
“Additionally, Fotowat et al. [28] and Trinh et al. [204] found cells in the hippocampal pallium of an electrosensory gymnotiform that presumably exhibit spatial navigation-related activity.”
From Spatial Cognition in Teleost Fish: Strategies and Mechanisms (2021) · cites this paper as [28]
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- Fotowat H Lee C Jun JJ Maler L 2019 Neural activity in a hippocampus-like region of the teleost pallium is associated with active sensing and navigation uO Research 10.20381/38902 PMC6469930 30942169 · DOI
- Vinepinsky E Perchik S Ben-Shahar O Donchin O Segev R 2018 Representation of border, velocity and speed in the goldfish brain bioRxiv 10.1101/291013 · DOI
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- Authors
- Fotowat, H., Lee, C., Jun, J. J., & Maler, L.
- Affiliations
- Harvard University (US)
- University of Ottawa (CA)
- Flatiron Institute (US)
- Department of Cellular and Molecular Medicine, Brain and Mind Institute and Centre for Neural Dynamics, University of Ottawa, Ottawa, Canada
- Venue
- eLife
- Publisher
- eLife Sciences Publications, Ltd
- Published
- 2019-04-03
- Volume
- 8
- ISSN
- 2050-084X (ISSN-L)
- PMC
- PMC6469930
- OpenAlex
- W2934040352
- Cited by
- 69
- References
- 90
- Citations by year
- 2026: 6 · 2025: 4 · 2024: 9 · 2023: 12 · 2022: 10 · 2021: 14 · 2020: 9 · 2019: 4 · 2018: 1
- FWCI
- 6.62
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- eLife (publishedVersion, cc-by)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- uO Research (University of Ottawa) (submittedVersion, public-domain)
- Funders
- Natural Sciences and Engineering Research Council of Canada (04336)
- Canadian Institutes of Health Research (153143)
- Topics
- Physical Sciences › Environmental Science › Nature and Landscape Conservation › Fish biology, ecology, and behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- active sensing, active navigation, weakly electric fish, Gymnotus, pallium, electric organ discharge, backward swimming, neuronal activity, wireless recording, teleost brain, spatial navigation
- MeSH terms
- Action Potentials, Animals, Electric Organ, Hippocampus, Neurons, Perception, Swimming, Gymnotiformes, Spatial Navigation
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