Zamore, Phillip D.
Howard Hughes Medical Institute · University of Massachusetts Chan Medical School
16 papers on CoChatORCID 0000-0002-4505-9618
Most cited papers
- Verified
Asymmetry in the Assembly of the RNAi Enzyme Complex
Schwarz, D. S., Hutvágner, G., Du, T., Xu, Z., Aronin, N., & Zamore, P. D. (2003) · Cell
RNA Interference and Gene DeliveryRNA Research and Splicing
Cited by 2,922
- Verified
A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA
Hutvágner, G., McLachlan, J., Pasquinelli, A. E., Bálint, E., Tuschl, T., & Zamore, P. D. (2001) · Science
MicroRNA in disease regulationRNA Interference and Gene Delivery
Cited by 2,781
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Passenger-Strand Cleavage Facilitates Assembly of siRNA into Ago2-Containing RNAi Enzyme Complexes
Matranga, C., Tomari, Y., Shin, C., Bartel, D. P., & Zamore, P. D. (2005) · Cell
RNA Interference and Gene DeliveryRNA Research and Splicing
Cited by 1,211
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Diversifying microRNA sequence and function
Ameres, S. L., & Zamore, P. D. (2013) · Nature Reviews Molecular Cell Biology
MicroRNA in disease regulationRNA Research and Splicing
Cited by 1,175
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Endogenous siRNAs Derived from Transposons and mRNAs in Drosophila Somatic Cells
Ghildiyal, M., Seitz, H., Horwich, M. D., Li, C., Du, T., Lee, S., Xu, J., Kittler, E. L. W., Zapp, M. L., Weng, Z., et al. (2008) · Science
Chromosomal and Genetic VariationsRNA Interference and Gene Delivery
Cited by 645
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Target RNA–Directed Trimming and Tailing of Small Silencing RNAs
Ameres, S. L., Horwich, M. D., Hung, J.-H., Xu, J., Ghildiyal, M., Weng, Z., & Zamore, P. D. (2010) · Science
RNA Interference and Gene DeliveryMicroRNA in disease regulation
Cited by 628
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Sequence-specific inhibition of small RNA function
Hutvágner, G., Simard, M. J., Mello, C. C., & Zamore, P. D. (2004) · PLoS Biology
RNA Interference and Gene DeliveryMicroRNA in disease regulation
Cited by 584
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Kinetic analysis of the RNAi enzyme complex
Haley, B., & Zamore, P. D. (2004) · Nature Structural & Molecular Biology
RNA Interference and Gene DeliveryRNA Research and Splicing
Cited by 544
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MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis
Ouimet, M., Ediriweera, H. N., Gundra, U. M., Sheedy, F. J., Ramkhelawon, B., Hutchison, S. B., Rinehold, K., van Solingen, C., Fullerton, M. D., Cecchini, K., et al. (2015) · Journal of Clinical Investigation
Atherosclerosis and Cardiovascular DiseasesMicroRNA in disease regulation
Cited by 394
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Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway
Ghildiyal, M., Xu, J., Seitz, H., Weng, Z., & Zamore, P. D. (2010) · RNA
RNA Interference and Gene DeliveryMicroRNA in disease regulation
Cited by 362
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Five siRNAs Targeting Three SNPs May Provide Therapy for Three-Quarters of Huntington's Disease Patients
Pfister, E. L., Kennington, L., Straubhaar, J., Wagh, S., Liu, W., DiFiglia, M., Landwehrmeyer, B., Vonsattel, J.-P., Zamore, P. D., & Aronin, N. (2009) · Current Biology
Genetic Neurodegenerative DiseasesRNA Interference and Gene Delivery
Cited by 261
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Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo
Hassler, M. R., Turanov, A. A., Alterman, J. F., Haraszti, R. A., Coles, A. H., Osborn, M. F., Echeverria, D., Nikan, M., Salomon, W. E., Roux, L., et al. (2018) · Nucleic Acids Research
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 181
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Argonaute Loading Improves the 5′ Precision of Both MicroRNAs and Their miRNA∗ Strands in Flies
Seitz, H., Ghildiyal, M., & Zamore, P. D. (2008) · Current Biology
MicroRNA in disease regulationRNA Interference and Gene Delivery
Cited by 172
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High-Throughput Analysis Reveals Rules for Target RNA Binding and Cleavage by AGO2
Becker, W. R., Ober-Reynolds, B., Jouravleva, K., Jolly, S. M., Zamore, P. D., & Greenleaf, W. J. (2019) · Molecular Cell
RNA Interference and Gene DeliveryCRISPR and Genetic Engineering
Cited by 161
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Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB
Jouravleva, K., Golovenko, D., Demo, G., Dutcher, R. C., Hall, T. M. T., Zamore, P. D., & Korostelev, A. A. (2022) · Molecular Cell
MicroRNA in disease regulationRNA Research and Splicing
Cited by 57
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Defining the roles of the Integrator, NEXT, and nuclear exosome complexes in Drosophila oogenesis
Lee, Y., Biasini, A., Tipping, C., Hong, S. H., & Zamore, P. D. (2025) · Cell Reports
RNA Research and SplicingNuclear Structure and Function
Cited by 6
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