A guiding map for inflammation
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Biologists, physicians and immunologists have contributed to the understanding of the cellular participants and biological pathways involved in inflammation. Here, we provide a general guide to the cellular and humoral contributors to inflammation as well as to the pathways that characterize inflammation in specific organs and tissues.
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Inflammation is an evolutionarily conserved process that activates immune and non-immune cells to protect the host from pathogens and promote tissue repair.
“Inflammation is an evolutionarily conserved process characterized by the activation of immune and non-immune cells that protect the host from bacteria, viruses, toxins and infections by eliminating pathogens and promoting tissue repair and recovery2,9.”
From Chronic inflammation in the etiology of disease across the life span (2019) · cites this paper as [2]
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The third international consensus definitions for sepsis and septic shock (Sepsis-3).
Singer, M., Deutschman, C. S., Seymour, C. W., Shankar-Hari, M., Annane, D., Bauer, M., Bellomo, R., Bernard, G. R., Chiche, J.-D., Coopersmith, C. M., et al. (2016) · JAMA · doi:10.1001/jama.2016.0287 · Cited by 28,250 · see citing works
Self-citationPathogen Recognition and Innate Immunity
Akira, S., Uematsu, S., & Takeuchi, O. (2006) · Cell · doi:10.1016/j.cell.2006.02.015 · Cited by 11,974 · see citing works
Mantovani, A., Allavena, P., Sica, A., & Balkwill, F. (2008) · Nature · doi:10.1038/nature07205 · Cited by 11,399 · see citing works
Self-citationPattern Recognition Receptors and Inflammation
Takeuchi, O., & Akira, S. (2010) · Cell · doi:10.1016/j.cell.2010.01.022 · Cited by 8,895 · see citing works
Inflammation and cancer: back to Virchow?
Balkwill, F., & Mantovani, A. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04046-0 · Cited by 7,746 · see citing works
Self-citationToll-like receptor control of the adaptive immune responses
Iwasaki, A., & Medzhitov, R. M. (2004) · Nature Immunology · doi:10.1038/ni1112 · Cited by 4,166 · see citing works
Innate and adaptive immune cells in the tumor microenvironment
Gajewski, T. F., Schreiber, H., & Fu, Y.-X. (2013) · Nature Immunology · doi:10.1038/ni.2703 · Cited by 4,148 · see citing works
Tumour-associated macrophages as treatment targets in oncology
Mantovani, A., Marchesi, F., Malesci, A., Laghi, L., & Allavena, P. (2017) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2016.217 · Cited by 4,065 · see citing works
Self-citationNLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
Duewell, P., Kono, H., Rayner, K. J., Sirois, C. M., Vladimer, G., Bauernfeind, F. G., Abela, G. S., Franchi, L., Nuñez, G., Schnurr, M., et al. (2010) · Nature · doi:10.1038/nature08938 · Cited by 4,026 · see citing works
Self-citationChronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases
Franceschi, C., & Campisi, J. (2014) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glu057 · Cited by 3,891 · see citing works
Kettenmann, H., Hanisch, U.-K., Noda, M., & Verkhratsky, A. (2011) · Physiological Reviews · doi:10.1152/physrev.00011.2010 · Cited by 3,547 · see citing works
Palmer, C. N. A., Irvine, A. D., Terron-Kwiatkowski, A., Zhao, Y., Liao, H., Lee, S. P., Goudie, D. R., Sandilands, A., Campbell, L. E., Smith, F. J. D., et al. (2006) · Nature Genetics · doi:10.1038/ng1767 · Cited by 2,978 · see citing works
Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy
Hotchkiss, R. S., Monneret, G., & Payen, D. (2013) · Nature Reviews Immunology · doi:10.1038/nri3552 · Cited by 2,772 · see citing works
Self-citationThe NALP3 inflammasome is involved in the innate immune response to amyloid-β
Halle, A., Hornung, V., Petzold, G. C., Stewart, C. R., Monks, B. G., Reinheckel, T., Fitzgerald, K. A., Latz, E., Moore, K. J., & Golenbock, D. T. (2008) · Nature Immunology · doi:10.1038/ni.1636 · Cited by 2,441 · see citing works
Self-citationEltzschig, H. K., & Carmeliet, P. (2011) · New England Journal of Medicine · doi:10.1056/nejmra0910283 · Cited by 2,061 · see citing works
The immunopathology of sepsis and potential therapeutic targets
van der Poll, T., van de Veerdonk, F. L., Scicluna, B. P., & Netea, M. G. (2017) · Nature Reviews Immunology · doi:10.1038/nri.2017.36 · Cited by 1,957 · see citing works
Self-citationRegulation and Functions of the IL-10 Family of Cytokines in Inflammation and Disease
Ouyang, W., Rutz, S., Crellin, N. K., Valdez, P. A., & Hymowitz, S. G. (2011) · Annual Review of Immunology · doi:10.1146/annurev-immunol-031210-101312 · Cited by 1,932 · see citing works
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
Larsen, C. M., Faulenbach, M., Vaag, A., Vølund, A., Ehses, J. A., Seifert, B., Mandrup-Poulsen, T., & Donath, M. Y. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa065213 · Cited by 1,798 · see citing works
Self-citationThe biology of innate lymphoid cells
Artis, D., & Spits, H. (2015) · Nature · doi:10.1038/nature14189 · Cited by 1,635 · see citing works
Liver Failure and Defective Hepatocyte Regeneration in Interleukin-6-Deficient Mice
Cressman, D. E., Greenbaum, L. E., DeAngelis, R. A., Ciliberto, G., Furth, E. E., Poli, V., & Taub, R. (1996) · Science · doi:10.1126/science.274.5291.1379 · Cited by 1,536 · see citing works
Innate immune activation in neurodegenerative disease
Heneka, M. T., Kummer, M. P., & Latz, E. (2014) · Nature Reviews Immunology · doi:10.1038/nri3705 · Cited by 1,437 · see citing works
Self-citationImmunopathogenesis of Rheumatoid Arthritis
Firestein, G. S., & McInnes, I. B. (2017) · Immunity · doi:10.1016/j.immuni.2017.02.006 · Cited by 1,301 · see citing works
Local proliferation dominates lesional macrophage accumulation in atherosclerosis
Robbins, C. S., Hilgendorf, I., Weber, G. F., Theurl, I., Iwamoto, Y., Figueiredo, J.-L., Gorbatov, R., Sukhova, G. K., Gerhardt, L. M. S., Smyth, D., et al. (2013) · Nature Medicine · doi:10.1038/nm.3258 · Cited by 1,041 · see citing works
Self-citationSutton, C. E., Brereton, C. F., Keogh, B., Mills, K. H. G., & Lavelle, E. C. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20060285 · Cited by 1,009 · see citing works
Self-citationSepsis: a roadmap for future research
Cohen, J., Vincent, J., Adhikari, N. K. J., Machado, F. R., Angus, D. C., Calandra, T., Jaton, K., Giulieri, S. G., Delaloye, J., Opal, S. M., et al. (2015) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(15)70112-x · Cited by 996 · see citing works
An Autoinflammatory Disease with Deficiency of the Interleukin-1–Receptor Antagonist
Aksentijevich, I. A., Masters, S. L., Ferguson, P. J., Dancey, P., Frenkel, J., van Royen‐Kerkhof, A., Laxer, R. M., Tedgård, U., Cowen, E. W., Pham, T., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0807865 · Cited by 981 · see citing works
Self-citationHistorical insights into cytokines
Dinarello, C. A. (2007) · European Journal of Immunology · doi:10.1002/eji.200737772 · Cited by 926 · see citing works
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Innate immunity in Alzheimer's disease
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Self-citationTargeting inflammation in the treatment of type 2 diabetes: time to start
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Pocock, J. M., & Kettenmann, H. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.07.007 · Cited by 650 · see citing works
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Gupta, J., Mitra, N., Kanetsky, P. A., Devaney, J., Wing, M. R., Reilly, M. P., Shah, V. O., Balakrishnan, V. S., Guzman, N. J., Girndt, M., et al. (2012) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.03500412 · Cited by 603 · see citing works
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Andersson, U., & Tracey, K. J. (2012) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-075015 · Cited by 414 · see citing works
Manthiram, K., Zhou, Q., Aksentijevich, I. A., & Kastner, D. L. (2017) · Nature Immunology · doi:10.1038/ni.3777 · Cited by 397 · see citing works
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Tonelli, M. A., Sacks, F. M., Pfeffer, M. A., Jhangri, G. S., & Curhan, G. C. (2005) · Kidney International · doi:10.1111/j.1523-1755.2005.00398.x · Cited by 358 · see citing works
Moran, A., Bundy, B. N., BECKER, D. J., DiMeglio, L. A., Gitelman, S. E., Goland, R., Greenbaum, C. J., Herold, K. C., Marks, J. B., Raskin, P., et al. (2013) · The Lancet · doi:10.1016/s0140-6736(13)60023-9 · Cited by 356 · see citing works
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Eyerich, K., Dimartino, V., & Cavani, A. (2017) · European Journal of Immunology · doi:10.1002/eji.201646723 · Cited by 324 · see citing works
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Mastrandrea, L. D., Yu, J., Behrens, T., Buchlis, J. G., Albini, C. H., Fourtner, S. H., & Quattrin, T. (2009) · Diabetes Care · doi:10.2337/dc09-0054 · Cited by 280 · see citing works
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- Authors
- Netea, M. G., Balkwill, F., Chonchol, M., Cominelli, F., Donath, M. Y., Giamarellos-Bourboulis, E. J., Golenbock, D., Gresnigt, M. S., Heneka, M. T., Hoffman, H. M., Hotchkiss, R., Joosten, L. A. B., Kastner, D. L., Korte, M., Latz, E., Libby, P., Mandrup-Poulsen, T., Mantovani, A., Mills, K. H. G., Nowak, K. L., O'Neill, L. A., Pickkers, P., van der Poll, T., Ridker, P. M., Schalkwijk, J., Schwartz, D. A., Siegmund, B., Steer, C. J., Tilg, H., van der Meer, J. W. M., van de Veerdonk, F. L., & Dinarello, C. A.
- Affiliations
- Radboud University Medical Center (NL)
- Queen Mary University of London (GB)
- University of Colorado Denver (US)
- Case Western Reserve University (US)
- University of Basel (CH)
- University of Massachusetts Chan Medical School (US)
- University of Bonn (DE)
- University of California San Diego (US)
- Washington University in St. Louis (US)
- Iuliu Hațieganu University of Medicine and Pharmacy (RO)
- National Institutes of Health (US)
- Brigham and Women's Hospital (US)
- University of Copenhagen (DK)
- Humanitas University (IT)
- Trinity College Dublin (IE)
- University of Colorado Anschutz (US)
- Charité – Universitätsmedizin Berlin (DE)
- University of Minnesota (US)
- Innsbruck Medical University (AT)
- Corresponding author
- Netea, Mihai G
- ORCID
- Netea, Mihai G
- Balkwill, Frances
- Chonchol, Michel
- Cominelli, Fabio
- Donath, Marc Y
- Giamarellos-Bourboulis, Evangelos J
- Golenbock, Douglas
- Gresnigt, Mark S
- Heneka, Michael T
- Hoffman, Hal M
- Hotchkiss, Richard
- Joosten, Leo A B
- Kastner, Daniel L
- Latz, Eicke
- Libby, Peter
- Mandrup-Poulsen, Thomas
- Mantovani, Alberto
- Mills, Kingston H G
- Nowak, Kristen L
- O'Neill, Luke A
- Pickkers, Peter
- Ridker, Paul M
- Schalkwijk, Joost
- Schwartz, David A
- Siegmund, Britta
- Steer, Clifford J
- Tilg, Herbert
- Dinarello, Charles A
- Venue
- Nature Immunology
- Published
- 2017-07-19
- Volume
- 18
- Issue
- 8
- Pages
- 826-831
- ISSN
- 1529-2908 (ISSN-L)
- 1529-2916
- PMC
- PMC5939996
- OpenAlex
- W2737388023
- Cited by
- 831
- References
- 54
- Citations by year
- 2026: 66 · 2025: 92 · 2024: 143 · 2023: 136 · 2022: 107 · 2021: 117 · 2020: 77 · 2019: 51 · 2018: 33 · 2017: 9
- FWCI
- 21.04
- Type
- journal article
- Language
- en
- Update notices
- correction (2020-12-07)
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Nature Immunology (publishedVersion)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Open Repository and Bibliography (University of Luxembourg) (submittedVersion, other-oa)
- Pure Amsterdam UMC (submittedVersion, other-oa)
- HZI (Helmholtz Centre for Infection Research) (submittedVersion, cc-by-nc-sa)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- DZNE Pub (submittedVersion)
- Queen Mary Research Online (Queen Mary University of London) (submittedVersion)
- Radboud Repository (Radboud University) (submittedVersion)
- Trinity's Access to Research Output (TARA) (Trinity College Dublin) (submittedVersion)
- Funders
- American Heart Association (12POST11920023)
- Cancer Research UK (16354, ERC322566, A16354)
- Science Foundation Ireland
- Deutsche Forschungsgemeinschaft (SPP-1656)
- Fondazione Cariplo
- Associazione Italiana per la Ricerca sul Cancro
- Dutch Arthritis Association (12-2-303)
- National Institutes of Health (DK091222,, AI‐15614, DK042191, DK097948, DK055812)
- National Heart, Lung, and Blood Institute (R01HL097163, HL080472, R01HL080472, R33HL120770, HL097163)
- National Human Genome Research Institute
- National Institute of Allergy and Infectious Diseases (R21AI102269, R01AI015614)
- National Institute of Diabetes and Digestive and Kidney Diseases (P01DK091222, R01DK055812, P01DK057880, R01DK056762, R56DK042191, R37DK042191, R01DK042191, P30DK067629, R56DK055812, T35DK111373, P30DK097948, R01DK125293)
- FP7 Ideas: European Research Council (310372)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Life Sciences › Immunology and Microbiology › Immunology › Inflammation biomarkers and pathways
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Inflammasome and immune disorders
- Keywords
- inflammation, inflammatory signaling, tissue-specific inflammation, immune cells
- MeSH terms
- Acute Disease, Chronic Disease, Communicable Diseases, Humans, Immunity, Cellular, Inflammation, Immunity, Humoral
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