Nestler, Eric J.

Historical review: molecular and cellular mechanisms of opiate and cocaine addiction

Nestler, E. J. (2004) · Trends in Pharmacological Sciences

Neurotransmitter Receptor Influence on BehaviorNeuropeptides and Animal Physiology

Cited by 425

Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression

Eisch, A. J., Bolaños, C. A., de Wit, J., Simonak, R. D., Pudiak, C. M., Barrot, M., Verhaagen, J., & Nestler, E. J. (2003) · Biological Psychiatry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 420

Epigenetics of the depressed brain: role of histone acetylation and methylation

Sun, H., Kennedy, P. J., & Nestler, E. J. (2013) · Neuropsychopharmacology

Epigenetics and DNA MethylationTreatment of Major Depression

Cited by 413

Genome-wide Analysis of Chromatin Regulation by Cocaine Reveals a Role for Sirtuins

Renthal, W., Kumar, A., Xiao, G., Wilkinson, M., Covington, H. E., Maze, I., Sikder, D., Robison, A. J., LaPlant, Q., Dietz, D. M., et al. (2009) · Neuron

Neurotransmitter Receptor Influence on BehaviorGenomics and Chromatin Dynamics

Cited by 409

Mesolimbic dopamine neurons in the brain reward circuit mediate susceptibility to social defeat and antidepressant action

Cao, J.-L., Covington, H. E., Friedman, A. K., Wilkinson, M. B., Walsh, J. J., Cooper, D. C., Nestler, E. J., & Han, M.-H. (2010) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

Cited by 402

Sex differences in nucleus accumbens transcriptome profiles associated with susceptibility versus resilience to subchronic variable stress

Hodes, G. E., Pfau, M. L., Purushothaman, I., Ahn, H. F., Golden, S. A., Christoffel, D. J., Magida, J., Brancato, A., Takahashi, A., Flanigan, M. E., et al. (2015) · The Journal of Neuroscience

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 395

Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2

Peña, C. J., Kronman, H. G., Walker, D. M., Cates, H. M., Bagot, R. C., Purushothaman, I., Issler, O., Loh, Y.-H. E., Leong, T., Kiraly, D. D., et al. (2017) · Science

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 394

Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal

Georgescu, D., Zachariou, V., Barrot, M., Mieda, M., Willie, J. T., Eisch, A. J., Yanagisawa, M., Nestler, E. J., & DiLeone, R. J. (2003) · The Journal of Neuroscience

Neuropeptides and Animal PhysiologySleep and Wakefulness Research

Cited by 373

The Neurobiology of Cocaine Addiction

Nestler, E. (2005) · Science & Practice Perspectives

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 367

Dopaminergic dynamics underlying sex-specific cocaine reward

Calipari, E. S., Juarez, B., Morel, C., Walker, D. M., Cahill, M. E., Ribeiro, E., Roman-Ortiz, C., Ramakrishnan, C., Deisseroth, K., Han, M.-H., et al. (2017) · Nature Communications

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 359

Neuroplasticity Mediated by Altered Gene Expression

McClung, C. A., & Nestler, E. J. (2008) · Neuropsychopharmacology

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 347

Paternal Transmission of Stress-Induced Pathologies

Dietz, D. M., LaPlant, Q., Watts, E. L., Hodes, G. E., Russo, S. J., Feng, J., Oosting, R. S., Vialou, V., & Nestler, E. J. (2011) · Biological Psychiatry

Stress Responses and CortisolNeuroendocrine regulation and behavior

Cited by 346

Epigenetic basis of mental illness

Nestler, E. J., Peña, C. J., Kundakovic, M., Mitchell, A., & Akbarian, S. (2016) · The Neuroscientist

Epigenetics and DNA MethylationStress Responses and Cortisol

Cited by 342

CREB regulation of nucleus accumbens excitability mediates social isolation–induced behavioral deficits

Wallace, D. L., Han, M.-H., Graham, D. L., Green, T. A., Vialou, V., Iñiguez, S. D., Cao, J.-L., Kirk, A., Chakravarty, S., Kumar, A., et al. (2009) · Nature Neuroscience

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 342

Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility

Bagot, R. C., Cates, H. M., Purushothaman, I., Lorsch, Z. S., Walker, D. M., Wang, J., Huang, X., Schlüter, O. M., Maze, I., Peña, C. J., et al. (2016) · Neuron

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 333

A 64-Tile 2.4-Mb In-Memory-Computing CNN Accelerator Employing Charge-Domain Compute

Valavi, H., Ramadge, P. J., Nestler, E., & Verma, N. (2019) · IEEE Journal of Solid-State Circuits

Advanced Memory and Neural ComputingLow-power high-performance VLSI design

Cited by 328

Involvement of cAMP-dependent protein kinase in the nucleus accumbens in cocaine self-administration and relapse of cocaine-seeking behavior

Self, D. W., Genova, L. M., Hope, B. T., Barnhart, W. J., Spencer, J. J., & Nestler, E. J. (1998) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 325

Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance

Lagace, D. C., Donovan, M. H., DeCarolis, N. A., Farnbauch, L. A., Malhotra, S., Berton, O., Nestler, E. J., Krishnan, V., & Eisch, A. J. (2010) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsStress Responses and Cortisol

Cited by 314

Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect

Newton, S. S., Thome, J., Wallace, T. L., Shirayama, Y., Schlesinger, L., Sakai, N., Chen, J., Neve, R., Nestler, E. J., & Duman, R. S. (2002) · The Journal of Neuroscience

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 313

Critical Role of Histone Turnover in Neuronal Transcription and Plasticity

Maze, I., Wenderski, W., Noh, K.-M., Bagot, R. C., Tzavaras, N., Purushothaman, I., Elsässer, S. J., Guo, Y., Ionete, C., Hurd, Y. L., et al. (2015) · Neuron

Genomics and Chromatin DynamicsNeuroscience and Neuropharmacology Research

Cited by 306

Neurobiology of Resilience: Interface Between Mind and Body

Cathomas, F., Murrough, J. W., Nestler, E. J., Han, M.-H., & Russo, S. J. (2019) · Biological Psychiatry

Resilience and Mental HealthStress Responses and Cortisol

Cited by 296

A Role for Repressive Histone Methylation in Cocaine-Induced Vulnerability to Stress

Covington, H. E., Maze, I., Sun, H., Bomze, H. M., DeMaio, K. D., Wu, E. Y., Dietz, D. M., Lobo, M. K., Ghose, S., Mouzon, E., et al. (2011) · Neuron

Neurotransmitter Receptor Influence on BehaviorEpigenetics and DNA Methylation

Cited by 289

Prefrontal Cortical Circuit for Depression- and Anxiety-Related Behaviors Mediated by Cholecystokinin: Role of ΔFosB

Vialou, V., Bagot, R. C., Cahill, M. E., Ferguson, D., Robison, A. J., Dietz, D. M., Fallon, B., Mazei-Robison, M., Ku, S. M., Harrigan, E., et al. (2014) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 283

Cocaine Regulates MEF2 to Control Synaptic and Behavioral Plasticity

Pulipparacharuvil, S., Renthal, W., Hale, C. F., Taniguchi, M., Xiao, G., Kumar, A., Russo, S. J., Sikder, D., Dewey, C. M., Davis, M. M., et al. (2008) · Neuron

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 281