Nestler, Eric J.

Essential role of brain-derived neurotrophic factor in adult hippocampal function

Monteggia, L. M., Barrot, M., Powell, C. M., Berton, O., Galanis, V., Gemelli, T., Meuth, S., Nagy, A., Greene, R. W., & Nestler, E. J. (2004) · Proceedings of the National Academy of Sciences

Nerve injury and regenerationMemory and Neural Mechanisms

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Essential Role of the Histone Methyltransferase G9a in Cocaine-Induced Plasticity

Maze, I., Covington, H. E., Dietz, D. M., LaPlant, Q., Renthal, W., Russo, S. J., Mechanic, M., Mouzon, E., Neve, R. L., Haggarty, S. J., et al. (2010) · Science

Neurotransmitter Receptor Influence on BehaviorEpigenetics and DNA Methylation

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The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens

Russo, S. J., Dietz, D. M., Dumitriu, D., Morrison, J. H., Malenka, R. C., & Nestler, E. J. (2010) · Trends in Neurosciences

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 654

The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress

Lutter, M., Sakata, I., Osborne-Lawrence, S., Rovinsky, S. A., Anderson, J. G., Jung, S., Birnbaum, S., Yanagisawa, M., Elmquist, J. K., Nestler, E. J., et al. (2008) · Nature Neuroscience

Regulation of Appetite and ObesityNeuropeptides and Animal Physiology

Cited by 644

Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine

Kelz, M. B., Chen, J., Carlezon, W. A., Whisler, K., Gilden, L., Beckmann, A. M., Steffen, C., Zhang, Y.-J., Marotti, L., Self, D. W., et al. (1999) · Nature

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 641

ΔFosB: A sustained molecular switch for addiction

Nestler, E. J., Barrot, M., & Self, D. W. (2001) · Proceedings of the National Academy of Sciences

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 640

Regulation of gene expression and cocaine reward by CREB and ΔFosB

McClung, C. A., & Nestler, E. J. (2003) · Nature Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 625

Antidepressant Actions of Histone Deacetylase Inhibitors

Covington, H. E., Maze, I., LaPlant, Q. C., Vialou, V. F., Ohnishi, Y. N., Berton, O., Fass, D. M., Renthal, W., Rush, A. J., Wu, E. Y., et al. (2009) · The Journal of Neuroscience

Histone Deacetylase Inhibitors ResearchTreatment of Major Depression

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Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex

Covington, H. E., Lobo, M. K., Maze, I., Vialou, V., Hyman, J. M., Zaman, S., LaPlant, Q., Mouzon, E., Ghose, S., Tamminga, C. A., et al. (2010) · The Journal of Neuroscience

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 621

Homeostatic and hedonic signals interact in the regulation of food intake

Lutter, M., & Nestler, E. J. (2009) · The Journal of Nutrition

Regulation of Appetite and ObesityEating Disorders and Behaviors

Cited by 614

Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens

LaPlant, Q., Vialou, V., Covington, H. E., Dumitriu, D., Feng, J., Warren, B. L., Maze, I., Dietz, D. M., Watts, E. L., Iñiguez, S. D., et al. (2010) · Nature Neuroscience

Neurotransmitter Receptor Influence on BehaviorEpigenetics and DNA Methylation

Cited by 612

Nuclear factor-κB is a critical mediator of stress-impaired neurogenesis and depressive behavior

Koo, J. W., Russo, S. J., Ferguson, D., Nestler, E. J., & Duman, R. S. (2010) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsStress Responses and Cortisol

Cited by 607

Opiates inhibit neurogenesis in the adult rat hippocampus

Eisch, A. J., Barrot, M., Schad, C. A., Self, D. W., & Nestler, E. J. (2000) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsNeuropeptides and Animal Physiology

Cited by 599

Histone Deacetylase 5 Epigenetically Controls Behavioral Adaptations to Chronic Emotional Stimuli

Renthal, W., Maze, I., Krishnan, V., Covington, H. E., Xiao, G., Kumar, A., Russo, S. J., Graham, A., Tsankova, N., Kippin, T. E., et al. (2007) · Neuron

Histone Deacetylase Inhibitors ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 599

Animal Models of Depression: Molecular Perspectives

Krishnan, V., & Nestler, E. J. (2011) · Current Topics in Behavioral Neurosciences

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 528

Altered Responsiveness to Cocaine and Increased Immobility in the Forced Swim Test Associated with Elevated cAMP Response Element-Binding Protein Expression in Nucleus Accumbens

Pliakas, A. M., Carlson, R. R., Neve, R. L., Konradi, C., Nestler, E. J., & Carlezon, W. A. (2001) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

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CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli

Barrot, M., Olivier, J. D. A., Perrotti, L. I., DiLeone, R. J., Berton, O., Eisch, A. J., Impey, S., Storm, D. R., Neve, R. L., Yin, J. C., et al. (2002) · Proceedings of the National Academy of Sciences

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

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Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors

Monteggia, L. M., Luikart, B., Barrot, M., Theobold, D., Malkovska, I., Nef, S., Parada, L. F., & Nestler, E. J. (2007) · Biological Psychiatry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 502

Regulation of dopaminergic transmission and cocaine reward by the Clock gene

McClung, C. A., Sidiropoulou, K., Vitaterna, M., Takahashi, J. S., White, F. J., Cooper, D. C., & Nestler, E. J. (2005) · Proceedings of the National Academy of Sciences

Neurotransmitter Receptor Influence on BehaviorCircadian rhythm and melatonin

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Opposite Modulation of Cocaine-Seeking Behavior by D 1 - and D 2 -Like Dopamine Receptor Agonists

Self, D. W., Barnhart, W. J., Lehman, D. A., & Nestler, E. J. (1996) · Science

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 492

Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression

Bagot, R. C., Parise, E. M., Peña, C. J., Zhang, H.-X., Maze, I., Chaudhury, D., Persaud, B., Cachope, R., Bolaños-Guzmán, C. A., Cheer, J. F., et al. (2015) · Nature Communications

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

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Initiation and adaptation: a paradigm for understanding psychotropic drug action

Hyman, S. E., & Nestler, E. J. (1996) · American Journal of Psychiatry

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

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ΔFosB in brain reward circuits mediates resilience to stress and antidepressant responses

Vialou, V., Robison, A. J., LaPlant, Q. C., Covington, H. E., Dietz, D. M., Ohnishi, Y. N., Mouzon, E., Rush, A. J., Watts, E. L., Wallace, D. L., et al. (2010) · Nature Neuroscience

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

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Histone Modifications at Gene Promoter Regions in Rat Hippocampus after Acute and Chronic Electroconvulsive Seizures

Tsankova, N. M., Kumar, A., & Nestler, E. J. (2004) · The Journal of Neuroscience

Electroconvulsive Therapy StudiesGenomics and Chromatin Dynamics

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