Nestler, Eric J.

Epigenetic mechanisms of drug addiction

Feng, J., & Nestler, E. J. (2013) · Current Opinion in Neurobiology

Epigenetics and DNA MethylationNeurotransmitter Receptor Influence on Behavior

Cited by 113

Role of Mesolimbic Brain-Derived Neurotrophic Factor in Depression

Koo, J. W., Chaudhury, D., Han, M.-H., & Nestler, E. J. (2019) · Biological Psychiatry

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

Cited by 112

Targeted Epigenetic Remodeling of the Cdk5 Gene in Nucleus Accumbens Regulates Cocaine- and Stress-Evoked Behavior

Heller, E. A., Hamilton, P. J., Burek, D. D., Lombroso, S. I., Peña, C. J., Neve, R. L., & Nestler, E. J. (2016) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorEpigenetics and DNA Methylation

Cited by 109

Chronic Ethanol Administration Regulates the Expression of GABAA Receptor α1 and α5 Subunits in the Ventral Tegmental Area and Hippocampus

Charlton, M. E., Sweetnam, P. M., Fitzgerald, L. W., Terwilliger, R. Z., Nestler, E. J., & Duman, R. S. (1997) · Journal of Neurochemistry

Neuroscience and Neuropharmacology ResearchNicotinic Acetylcholine Receptors Study

Cited by 109

Histone acetylation in drug addiction

Renthal, W., & Nestler, E. J. (2009) · Seminars in Cell & Developmental Biology

Genomics and Chromatin DynamicsNeurotransmitter Receptor Influence on Behavior

Cited by 109

Role of the Brain's Reward Circuitry in Depression

Nestler, E. J. (2015) · International review of neurobiology

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

Cited by 108

Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons

Kronman, H., Torres-Berrío, A., Sidoli, S., Issler, O., Godino, A., Ramakrishnan, A., Mews, P., Lardner, C. K., Parise, E. M., Walker, D. M., et al. (2021) · Nature Neuroscience

Stress Responses and CortisolEpigenetics and DNA Methylation

Cited by 108

Fluoxetine Epigenetically Alters the CaMKIIα Promoter in Nucleus Accumbens to Regulate ΔFosB Binding and Antidepressant Effects

Robison, A. J., Vialou, V., Sun, H.-S., Labonte, B., A Golden, S., Dias, C., Turecki, G., Tamminga, C., Russo, S., Mazei-Robison, M., et al. (2014) · Neuropsychopharmacology

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 105

Estrogen receptor α drives pro-resilient transcription in mouse models of depression

Lorsch, Z. S., Loh, Y.-H. E., Purushothaman, I., Walker, D. M., Parise, E. M., Salery, M., Cahill, M. E., Hodes, G. E., Pfau, M. L., Kronman, H., et al. (2018) · Nature Communications

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 104

Extracellular Signal-Regulated Kinase-2 within the Ventral Tegmental Area Regulates Responses to Stress

Iñiguez, S. D., Vialou, V., Warren, B. L., Cao, J.-L., Alcantara, L. F., Davis, L. C., Manojlovic, Z., Neve, R. L., Russo, S. J., Han, M.-H., et al. (2010) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 103

Induction of Cyclin-Dependent Kinase 5 in the Hippocampus by Chronic Electroconvulsive Seizures: Role of ΔFosB

Chen, J., Zhang, Y., Kelz, M. B., Steffen, C., Ang, E. S., Zeng, L., & Nestler, E. J. (2000) · The Journal of Neuroscience

Electroconvulsive Therapy StudiesTreatment of Major Depression

Cited by 101

Nucleus accumbens dopamine mediates amphetamine-induced impairment of social bonding in a monogamous rodent species

Liu, Y., Aragona, B. J., Young, K. A., Dietz, D. M., Kabbaj, M., Mazei-Robison, M., Nestler, E. J., & Wang, Z. (2010) · Proceedings of the National Academy of Sciences

Neurotransmitter Receptor Influence on BehaviorNeuroendocrine regulation and behavior

Cited by 101

Analytical tools and current challenges in the modern era of neuroepigenomics

Maze, I., Shen, L., Zhang, B., Garcia, B. A., Shao, N., Mitchell, A., Sun, H., Akbarian, S., Allis, C. D., & Nestler, E. J. (2014) · Nature Neuroscience

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 100

Distinct sites of opiate reward and aversion within the midbrain identified using a herpes simplex virus vector expressing GluR1

Carlezon, W. A., Haile, C. N., Coppersmith, R., Hayashi, Y., Malinow, R., Neve, R. L., & Nestler, E. J. (2000) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 98

From synapse to nucleus: Novel targets for treating depression

Covington, H. E., Vialou, V., & Nestler, E. J. (2010) · Neuropharmacology

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 98

Antidepressant action of HDAC inhibition in the prefrontal cortex

Covington, H. E., Maze, I., Vialou, V., & Nestler, E. J. (2015) · Neuroscience

Histone Deacetylase Inhibitors ResearchTreatment of Major Depression

Cited by 97

Environmental programming of susceptibility and resilience to stress in adulthood in male mice

Peña, C. J., Nestler, E. J., & Bagot, R. C. (2019) · Frontiers in Behavioral Neuroscience

Stress Responses and CortisolChild Abuse and Trauma

Cited by 97

The role of ventral striatal cAMP signaling in stress-induced behaviors

Plattner, F., Hayashi, K., Hernández, A., Benavides, D. R., Tassin, T. C., Tan, C., Day, J., Fina, M. W., Yuen, E. Y., Yan, Z., et al. (2015) · Nature Neuroscience

Phosphodiesterase function and regulationNeurotransmitter Receptor Influence on Behavior

Cited by 94

Serum Response Factor Promotes Resilience to Chronic Social Stress through the Induction of ΔFosB

Vialou, V., Maze, I., Renthal, W., LaPlant, Q. C., Watts, E. L., Mouzon, E., Ghose, S., Tamminga, C. A., & Nestler, E. J. (2010) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 91

ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior

Sun, H., Damez-Werno, D. M., Scobie, K. N., Shao, N.-Y., Dias, C., Rabkin, J., Koo, J. W., Korb, E., Bagot, R. C., Ahn, F. H., et al. (2015) · Nature Medicine

Stress Responses and CortisolTreatment of Major Depression

Cited by 91

Herpes simplex virus-mediated gene transfer as a tool for neuropsychiatric research

Carlezon, Jr., Nestler, E. J., & Neve, R. L. (2000) · Critical Reviews™ in Neurobiology

Virus-based gene therapy researchHerpesvirus Infections and Treatments

Cited by 90

α1- and β3-Adrenergic Receptor–Mediated Mesolimbic Homeostatic Plasticity Confers Resilience to Social Stress in Susceptible Mice

Zhang, H., Chaudhury, D., Nectow, A. R., Friedman, A. K., Zhang, S., Juarez, B., Liu, H., Pfau, M. L., Aleyasin, H., Jiang, C., et al. (2019) · Biological Psychiatry

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 88

Progress in Epigenetics of Depression

Peña, C. J., & Nestler, E. J. (2018) · Progress in Molecular Biology and Translational Science

Epigenetics and DNA MethylationStress Responses and Cortisol

Cited by 84

MiR-218: a molecular switch and potential biomarker of susceptibility to stress

Torres-Berrío, A., Nouel, D., Cuesta, S., Parise, E. M., Restrepo-Lozano, J. M., Larochelle, P., Nestler, E. J., & Flores, C. (2020) · Molecular Psychiatry

MicroRNA in disease regulationTreatment of Major Depression

Cited by 79