Weindruch, Richard

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

Colman, R. J., Anderson, R. M., Johnson, S. C., Kastman, E. K., Kosmatka, K. J., Beasley, T. M., Allison, D. B., Cruzen, C., Simmons, H. A., Kemnitz, J. W., et al. (2009) · Science

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 2,277

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

Kujoth, G. C., Hiona, A., Pugh, T. D., Someya, S., Panzer, K., Wohlgemuth, S. E., Hofer, T., Seo, A. Y., Sullivan, R., Jobling, W. A., et al. (2005) · Science

Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms

Cited by 2,165

Gene expression profile of aging and its retardation by caloric restriction

Lee, C.-K., Klopp, R. G., Weindruch, R., & Prolla, T. A. (1999) · Science

Genetics, Aging, and Longevity in Model OrganismsMuscle Physiology and Disorders

Cited by 1,473

SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells

Haigis, M. C., Mostoslavsky, R., Haigis, K. M., Fahie, K., Christodoulou, D. C., Murphy, A. J., Valenzuela, D. M., Yancopoulos, G. D., Karow, M., Blander, G., et al. (2006) · Cell

Sirtuins and Resveratrol in MedicinePancreatic function and diabetes

Cited by 1,162

Gene-expression profile of the ageing brain in mice

Lee, C.-K., Weindruch, R., & Prolla, T. A. (2000) · Nature Genetics

Genetics, Aging, and Longevity in Model OrganismsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,055

Caloric restriction improves health and survival of rhesus monkeys

Mattison, J. A., Colman, R. J., Beasley, T. M., Allison, D. B., Kemnitz, J. W., Roth, G. S., Ingram, D. K., Weindruch, R., de Cabo, R., & Anderson, R. M. (2017) · Nature Communications

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 838

Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys

Colman, R. J., Beasley, T. M., Kemnitz, J. W., Johnson, S. C., Weindruch, R., & Anderson, R. M. (2014) · Nature Communications

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 711

A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice

Barger, J. L., Kayo, T., Vann, J. M., Arias, E. B., Wang, J., Hacker, T. A., Wang, Y., Raederstorff, D., Morrow, J. D., Leeuwenburgh, C., et al. (2008) · PLoS ONE

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 580

Influences of aging and caloric restriction on the transcriptional profile of skeletal muscle from rhesus monkeys

Kayo, T., Allison, D. B., Weindruch, R., & Prolla, T. A. (2001) · Proceedings of the National Academy of Sciences

Genetics, Aging, and Longevity in Model OrganismsMuscle Physiology and Disorders

Cited by 384

Dietary Restriction Benefits Learning and Motor Performance of Aged Mice

Ingram, D. K., Weindruch, R., Spangler, E. L., Freeman, J. R., & Walford, R. L. (1987) · Journal of Gerontology

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 342

Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts

Lee, C.-K., Allison, D. B., Brand, J., Weindruch, R., & Prolla, T. A. (2002) · Proceedings of the National Academy of Sciences

Genetics, Aging, and Longevity in Model OrganismsCardiovascular Function and Risk Factors

Cited by 314

Dynamic regulation of PGC‐1α localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response

Anderson, R. M., Barger, J. L., Edwards, M. G., Braun, K. H., O’Connor, C. E., Prolla, T. A., & Weindruch, R. (2008) · Aging Cell

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 283

Caloric Restriction and Aging: Studies in Mice and Monkeys

Anderson, R. M., Shanmuganayagam, D., & Weindruch, R. (2009) · Toxicologic Pathology

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 276

Statistical methods for testing effects on “maximum lifespan”

Wang, C., Li, Q., Redden, D. T., Weindruch, R., & Allison, D. B. (2004) · Mechanisms of Ageing and Development

Genetics, Aging, and Longevity in Model OrganismsStatistical Distribution Estimation and Applications

Cited by 208

Influences of Aging and Dietary Restriction on Serum Thymosin l Levels in Mice

Weindruch, R., Naylor, P. H., Goldstein, A. L., & Walford, R. L. (1988) · Journal of Gerontology

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 207

Gene expression profiling of aging reveals activation of a p53-mediated transcriptional program

Edwards, M. G., Anderson, R. M., Yuan, M., Kendziorski, C. M., Weindruch, R., & Prolla, T. A. (2007) · BMC Genomics

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 174

Adipose tissue energy metabolism: altered gene expression profile of mice subjected to long-term caloric restriction

Higami, Y., Pugh, T. D., Page, G. P., Allison, D. B., Prolla, T. A., & Weindruch, R. (2004) · The FASEB Journal

Adipose Tissue and MetabolismGenetics, Aging, and Longevity in Model Organisms

Cited by 173

Long-term caloric restriction increases UCP3 content but decreases proton leak and reactive oxygen species production in rat skeletal muscle mitochondria

Bevilacqua, L., Ramsey, J. J., Hagopian, K., Weindruch, R., & Harper, M.-E. (2005) · American Journal of Physiology-Endocrinology and Metabolism

Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms

Cited by 172

The retardation of aging by caloric restriction: its significance in the transgenic era

Barger, J. L., Walford, R. L., & Weindruch, R. (2003) · Experimental Gerontology

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 160

Attenuation of sarcopenia by dietary restriction in rhesus monkeys

Colman, R. J., Beasley, T. M., Allison, D. B., & Weindruch, R. (2008) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Nutrition and Health in AgingGenetics, Aging, and Longevity in Model Organisms

Cited by 141

Gene expression profiling of aging in multiple mouse strains: identification of aging biomarkers and impact of dietary antioxidants

Park, S., Kim, K., Page, G. P., Allison, D. B., Weindruch, R., & Prolla, T. A. (2009) · Aging Cell

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 134

Energy Expenditure of Rhesus Monkeys Subjected to 11 Years of Dietary Restriction

Blanc, S., Schoeller, D., Kemnitz, J., Weindruch, R., Colman, R., Newton, W., Wink, K., Baum, S., & Ramsey, J. (2003) · The Journal of Clinical Endocrinology & Metabolism

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 128

Energy restriction lowers the expression of genes linked to inflammation, the cytoskeleton, the extracellular matrix, and angiogenesis in mouse adipose tissue

Higami, Y., Barger, J. L., Page, G. P., Allison, D. B., Smith, S. R., Prolla, T. A., & Weindruch, R. (2006) · The Journal of Nutrition

Adipokines, Inflammation, and Metabolic DiseasesDietary Effects on Health

Cited by 126

A calorie-restricted diet decreases brain iron accumulation and preserves motor performance in old rhesus monkeys

Kastman, E. K., Willette, A. A., Coe, C. L., Bendlin, B. B., Kosmatka, K. J., McLaren, D. G., Xu, G., Canu, E., Field, A. S., Alexander, A. L., et al. (2010) · Journal of Neuroscience

Genetics, Aging, and Longevity in Model OrganismsNeurological diseases and metabolism

Cited by 85