Most cited biochemistry, genetics and molecular biology papers
- Verified
Rituximab, B-lymphocyte depletion, and preservation of beta-cell function
Pescovitz, M. D., Greenbaum, C. J., Krause-Steinrauf, H., Becker, D. J., Gitelman, S. E., Goland, R., Gottlieb, P. A., Marks, J. B., McGee, P. F., Moran, A. M., et al. (2009) · New England Journal of Medicine
Diabetes and associated disordersT-cell and B-cell Immunology
Cited by 1,093
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Mesenchymal Stem Cells for Regenerative Medicine
Han, Y., Li, X., Zhang, Y., Han, Y., Chang, F., & Ding, J. (2019) · Cells
Mesenchymal stem cell researchPeriodontal Regeneration and Treatments
Cited by 1,093
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Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E
Fingar, D. C., Salama, S., Tsou, C., Harlow, E., & Blenis, J. (2002) · Genes & Development
PI3K/AKT/mTOR signaling in cancerRNA and protein synthesis mechanisms
Cited by 1,093
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Control of brain development, function, and behavior by the microbiome
Sampson, T. R., & Mazmanian, S. K. (2015) · Cell Host & Microbe
Gut microbiota and healthTryptophan and brain disorders
Cited by 1,093
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S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury
Cho, D.-H., Nakamura, T., Fang, J., Cieplak, P., Godzik, A., Gu, Z., & Lipton, S. A. (2009) · Science
Mitochondrial Function and PathologyAlzheimer's disease research and treatments
Cited by 1,092
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c-Myc transactivation of LDH-A : Implications for tumor metabolism and growth
Shim, H., Dolde, C., Lewis, B. C., Wu, C.-S., Dang, G., Jungmann, R. A., Dalla-Favera, R., & Dang, C. V. (1997) · Proceedings of the National Academy of Sciences
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 1,092
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Hypoxia-inducible factor 1: master regulator of O2 homeostasis
Semenza, G. L. (1998) · Current Opinion in Genetics & Development
Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment
Cited by 1,092
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Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
Polo, S. E., & Jackson, S. P. (2011) · Genes & Development
DNA Repair MechanismsGenomics and Chromatin Dynamics
Cited by 1,092
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Epidemiology of type 1 diabetes
Maahs, D. M., West, N. A., Lawrence, J. M., & Mayer-Davis, E. J. (2010) · Endocrinology and Metabolism Clinics of North America
Diabetes and associated disordersDiabetes Management and Research
Cited by 1,092
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p300/CBP proteins: HATs for transcriptional bridges and scaffolds
Chan, H. M., & La Thangue, N. B. (2001) · Journal of Cell Science
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 1,092
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Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
Gao, Y., Dickerson, J. B., Guo, F., Zheng, J., & Zheng, Y. (2004) · Proceedings of the National Academy of Sciences
Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases
Cited by 1,091
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ATR-Mediated Checkpoint Pathways Regulate Phosphorylation and Activation of Human Chk1
Zhao, H., & Piwnica-Worms, H. (2001) · Molecular and Cellular Biology
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 1,091
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The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis
Shilatifard, A. (2012) · Annual Review of Biochemistry
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 1,091
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MOFA+: a statistical framework for comprehensive integration of multi-modal single-cell data
Argelaguet, R., Arnol, D., Bredikhin, D., Deloro, Y., Velten, B., Marioni, J. C., & Stegle, O. (2020) · Genome Biology
Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks
Cited by 1,091
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ChAMP: updated methylation analysis pipeline for Illumina BeadChips
Tian, Y., Morris, T. J., Webster, A. P., Yang, Z., Beck, S., Feber, A., & Teschendorff, A. E. (2017) · Bioinformatics
Epigenetics and DNA MethylationGene expression and cancer classification
Cited by 1,091
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Selective Targeting of a Redox-active Ubiquinone to Mitochondria within Cells
Kelso, G. F., Porteous, C. M., Coulter, C. V., Hughes, G., Porteous, W. K., Ledgerwood, E. C., Smith, R. A. J., & Murphy, M. P. (2001) · Journal of Biological Chemistry
Coenzyme Q10 studies and effectsMitochondrial Function and Pathology
Cited by 1,091
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Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ Subunits
Tang, W.-J., & Gilman, A. G. (1991) · Science
Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling
Cited by 1,091
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An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
Bürckstümmer, T., Baumann, C., Blüml, S., Dixit, E., Dürnberger, G., Jahn, H., Planyavsky, M., Bilban, M., Colinge, J., Bennett, K. L., et al. (2009) · Nature Immunology
Inflammasome and immune disordersinterferon and immune responses
Cited by 1,091
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The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration
Heras-Sandoval, D., Pérez-Rojas, J. M., Hernández-Damián, J., & Pedraza-Chaverri, J. (2014) · Cellular Signalling
Autophagy in Disease and TherapyPI3K/AKT/mTOR signaling in cancer
Cited by 1,091
- Verified
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
Meloche, S., & Pouysségur, J. (2007) · Oncogene
Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways
Cited by 1,091
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Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes
Bray, M.-A., Singh, S., Han, H., Davis, C. T., Borgeson, B., Hartland, C., Kost-Alimova, M., Gustafsdottir, S. M., Gibson, C. C., & Carpenter, A. E. (2016) · Nature Protocols
Cell Image Analysis TechniquesSingle-cell and spatial transcriptomics
Cited by 1,090
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High-throughput generation, optimization and analysis of genome-scale metabolic models
Henry, C. S., DeJongh, M., Best, A. A., Frybarger, P. M., Linsay, B., & Stevens, R. L. (2010) · Nature Biotechnology
Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis
Cited by 1,090
- Verified
Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
Hendel, A., Bak, R. O., Clark, J. T., Kennedy, A. B., Ryan, D. E., Roy, S., Steinfeld, I., Lunstad, B. D., Kaiser, R. J., Wilkens, A. B., et al. (2015) · Nature Biotechnology
CRISPR and Genetic EngineeringRNA Interference and Gene Delivery
Cited by 1,090
- Verified
Histone deacetylase inhibitor selectively induces p21 WAF1 expression and gene-associated histone acetylation
Richon, V. M., Sandhoff, T. W., Rifkind, R. A., & Marks, P. A. (2000) · Proceedings of the National Academy of Sciences
Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics
Cited by 1,090
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