Most cited biochemistry, genetics and molecular biology papers
- Verified
Prediction of Mammalian MicroRNA Targets
Lewis, B. P., Shih, I.-H., Jones-Rhoades, M. W., Bartel, D. P., & Burge, C. B. (2003) · Cell
MicroRNA in disease regulationPlant Molecular Biology Research
Cited by 5,199
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Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation
McCarthy, D. J., Chen, Y., & Smyth, G. K. (2012) · Nucleic Acids Research
Gene expression and cancer classificationGenomics and Phylogenetic Studies
Cited by 5,195
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Landscape of transcription in human cells
Djebali, S., Davis, C. A., Merkel, A., Dobin, A., Lassmann, T., Mortazavi, A., Tanzer, A., Lagarde, J., Lin, W., Schlesinger, F., et al. (2012) · Nature
Genomics and Chromatin DynamicsRNA Research and Splicing
Cited by 5,187
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Alternative isoform regulation in human tissue transcriptomes
Wang, E. T., Sandberg, R., Luo, S., Khrebtukova, I., Zhang, L., Mayr, C., Kingsmore, S. F., Schroth, G. P., & Burge, C. B. (2008) · Nature
RNA Research and SplicingRNA regulation and disease
Cited by 5,181
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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
Maxwell, P. H., Wiesener, M. S., Chang, G.-W., Clifford, S. C., Vaux, E. C., Cockman, M. E., Wykoff, C. C., Pugh, C. W., Maher, E. R., & Ratcliffe, P. J. (1999) · Nature
Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment
Cited by 5,180
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Hypoxia — a key regulatory factor in tumour growth
Harris, A. L. (2002) · Nature Reviews Cancer
Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer
Cited by 5,177
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Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c
Liu, X., Kim, C. N., Yang, J., Jemmerson, R., & Wang, X. (1996) · Cell
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 5,167
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Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
Kessenbrock, K., Plaks, V., & Werb, Z. (2010) · Cell
Protease and Inhibitor MechanismsTGF-β signaling in diseases
Cited by 5,151
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The Warburg Effect: How Does it Benefit Cancer Cells?
Liberti, M. V., & Locasale, J. W. (2016) · Trends in Biochemical Sciences
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 5,150
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Photodynamic therapy of cancer: An update
Agostinis, P., Berg, K., Cengel, K. A., Foster, T. H., Girotti, A. W., Gollnick, S. O., Hahn, S. M., Hamblin, M. R., Juzeniene, A., Kessel, D., et al. (2011) · CA: A Cancer Journal for Clinicians
Photodynamic Therapy Research StudiesNanoplatforms for cancer theranostics
Cited by 5,145
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Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.
Simonet, W. S., Lacey, D. L., Dunstan, C. R., Kelley, M., Chang, M.-S., Lüthy, R., Nguyen, H. Q., Wooden, S., Bennett, L., Boone, T., et al. (1997) · Cell
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 5,130
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Infrared spectroscopy of proteins
Barth, A. (2007) · Biochimica et Biophysica Acta (BBA) - Bioenergetics
Spectroscopy Techniques in Biomedical and Chemical ResearchProtein Structure and Dynamics
Cited by 5,129
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Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials
Clarke, M. J. (2005) · The Lancet
Breast Cancer Treatment StudiesBreast Lesions and Carcinomas
Cited by 5,127
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I-TASSER server for protein 3D structure prediction
Zhang, Y. (2008) · BMC Bioinformatics
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 5,124
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UniProt: a hub for protein information
The UniProt Consortium (2015) · Nucleic Acids Research
Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks
Cited by 5,106
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Tumour exosome integrins determine organotropic metastasis
Hoshino, A., Costa-Silva, B., Shen, T.-L., Rodrigues, G., Hashimoto, A., Tesic Mark, M., Molina, H., Kohsaka, S., Di Giannatale, A., Ceder, S., et al. (2015) · Nature
Extracellular vesicles in diseaseCancer Cells and Metastasis
Cited by 5,101
- Verified
The zebrafish reference genome sequence and its relationship to the human genome.
Howe, K., Clark, M. D., Torroja, C. F., Torrance, J., Berthelot, C., Muffato, M., Collins, J. E., Humphray, S., McLaren, K., Matthews, L., et al. (2013) · Nature
Zebrafish Biomedical Research ApplicationsGenomics and Phylogenetic Studies
Cited by 5,100
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ViennaRNA Package 2.0
Lorenz, R., Bernhart, S. H., Höner zu Siederdissen, C., Tafer, H., Flamm, C., Stadler, P. F., & Hofacker, I. L. (2011) · Algorithms for Molecular Biology
RNA and protein synthesis mechanismsGenomics and Phylogenetic Studies
Cited by 5,098
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Sensitive protein alignments at tree-of-life scale using DIAMOND
Buchfink, B., Reuter, K., & Drost, H.-G. (2021) · Nature Methods
Genomics and Phylogenetic StudiesAlgorithms and Data Compression
Cited by 5,097
- Verified
Triple-negative breast cancer: clinical features and patterns of recurrence
Dent, R., Trudeau, M., Pritchard, K. I., Hanna, W. M., Kahn, H. K., Sawka, C. A., Lickley, L. A., Rawlinson, E., Sun, P., & Narod, S. A. (2007) · Clinical Cancer Research
Breast Cancer Treatment StudiesBreast Lesions and Carcinomas
Cited by 5,091
- Verified
Mitochondrial formation of reactive oxygen species
Turrens, J. F. (2003) · The Journal of Physiology
Mitochondrial Function and PathologyRedox biology and oxidative stress
Cited by 5,084
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miRBase: annotating high confidence microRNAs using deep sequencing data
Kozomara, A., & Griffiths-Jones, S. (2014) · Nucleic Acids Research
MicroRNA in disease regulationGenomics and Phylogenetic Studies
Cited by 5,073
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Reversed graph embedding resolves complex single-cell trajectories
Qiu, X., Mao, Q., Tang, Y., Wang, L., Chawla, R., Pliner, H. A., & Trapnell, C. (2017) · Nature Methods
Single-cell and spatial transcriptomicsGene Regulatory Network Analysis
Cited by 5,070
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Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies
Bettegowda, C., Sausen, M., Leary, R. J., Kinde, I., Wang, Y., Agrawal, N., Bartlett, B. R., Wang, H., Luber, B., Alani, R. M., et al. (2014) · Science Translational Medicine
Cancer Genomics and DiagnosticsPrenatal Screening and Diagnostics
Cited by 5,067
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