Most cited biochemistry, genetics and molecular biology papers
- Verified
The Future of Genetic Studies of Complex Human Diseases
Risch, N., & Merikangas, K. (1996) · Science
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 5,355
- Verified
TNT, a free program for phylogenetic analysis
Goloboff, P. A., Farris, J. S., & Nixon, K. C. (2008) · Cladistics
Genomics and Phylogenetic StudiesEvolution and Paleontology Studies
Cited by 5,352
- Verified · note
The Pathobiology of Diabetic Complications
Brownlee, M. (2005) · Diabetes
Advanced Glycation End Products researchDiabetes Management and Research
Cited by 5,339
- Verified
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
Sies, H., & Jones, D. P. (2020) · Nature Reviews Molecular Cell Biology
Redox biology and oxidative stressNitric Oxide and Endothelin Effects
Cited by 5,335
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Insulin signalling and the regulation of glucose and lipid metabolism
Saltiel, A. R., & Kahn, C. R. (2001) · Nature
Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins
Cited by 5,326
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Gout-associated uric acid crystals activate the NALP3 inflammasome
Martinon, F., Pétrilli, V., Mayor, A., Tardivel, A., & Tschopp, J. (2006) · Nature
Inflammasome and immune disordersGout, Hyperuricemia, Uric Acid
Cited by 5,326
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The Wnt Signaling Pathway in Development and Disease
Logan, C. Y., & Nusse, R. (2004) · Annual Review of Cell and Developmental Biology
Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation
Cited by 5,325
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Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
Walker, J. E., Saraste, M., Runswick, M. J., & Gay, N. J. (1982) · The EMBO Journal
ATP Synthase and ATPases ResearchEnzyme Structure and Function
Cited by 5,312
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Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation
O'Brien, J., Hayder, H., Zayed, Y., & Peng, C. (2018) · Frontiers in Endocrinology
MicroRNA in disease regulationPlant Molecular Biology Research
Cited by 5,287
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The Microbiota-Gut-Brain Axis
Cryan, J. F., O'Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., et al. (2019) · Physiological Reviews
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 5,286
- Verified
Population Structure and Eigenanalysis
Patterson, N., Price, A. L., & Reich, D. (2006) · PLoS Genetics
Genetic diversity and population structureForensic and Genetic Research
Cited by 5,280
- Verified
Host-Bacterial Mutualism in the Human Intestine
Bäckhed, F., Ley, R. E., Sonnenburg, J. L., Peterson, D. A., & Gordon, J. I. (2005) · Science
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 5,277
- Verified
ShinyGO: a graphical gene-set enrichment tool for animals and plants
Ge, S. X., Jung, D., & Yao, R. (2020) · Bioinformatics
Bioinformatics and Genomic NetworksGenomics and Phylogenetic Studies
Cited by 5,270
- Verified
UCSF ChimeraX: Meeting modern challenges in visualization and analysis
Goddard, T. D., Huang, C. C., Meng, E. C., Pettersen, E. F., Couch, G. S., Morris, J. H., & Ferrin, T. E. (2018) · Protein Science
Enzyme Structure and FunctionComputer Graphics and Visualization Techniques
Cited by 5,267
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CAP3: A DNA Sequence Assembly Program
Huang, X., & Madan, A. (1999) · Genome Research
Genomics and Phylogenetic StudiesAlgorithms and Data Compression
Cited by 5,261
- Verified
Versatile and open software for comparing large genomes
Kurtz, S., Phillippy, A., Delcher, A. L., Smoot, M., Shumway, M., Antonescu, C., & Salzberg, S. L. (2004) · Genome Biology
Genomics and Phylogenetic StudiesGenome Rearrangement Algorithms
Cited by 5,254
- Verified
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
Cross, D. A. E., Alessi, D. R., Cohen, P., Andjelkovich, M., & Hemmings, B. A. (1995) · Nature
PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling
Cited by 5,244
- Verified
Genome-scale CRISPR-Cas9 knockout screening in human cells
Shalem, O., Sanjana, N. E., Hartenian, E., Shi, X., Scott, D. A., Mikkelsen, T. S., Heckl, D., Ebert, B. L., Root, D. E., Doench, J. G., et al. (2014) · Science
CRISPR and Genetic EngineeringChromatin Remodeling and Cancer
Cited by 5,234
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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
The ENCODE Project Consortium (2007) · Nature
Genomics and Chromatin DynamicsChromosomal and Genetic Variations
Cited by 5,223
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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
Serrano, M., Lin, A. W., McCurrach, M. E., Beach, D., & Lowe, S. W. (1997) · Cell
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 5,218
- Verified
The senescence-associated secretory phenotype: the dark side of tumor suppression
Coppé, J.-P., Desprez, P.-Y., Krtolica, A., & Campisi, J. (2010) · Annual Review of Pathology: Mechanisms of Disease
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 5,206
- Verified
METAL: fast and efficient meta-analysis of genomewide association scans
Willer, C. J., Li, Y., & Abecasis, G. R. (2010) · Bioinformatics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 5,205
- Verified
A New Initiative on Precision Medicine
Collins, F. S., & Varmus, H. (2015) · New England Journal of Medicine
Science, Research, and MedicineCancer Genomics and Diagnostics
Cited by 5,202
- Verified
Inferring the historical patterns of biological evolution
Pagel, M. (1999) · Nature
Genomics and Phylogenetic StudiesEvolution and Paleontology Studies
Cited by 5,200
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