Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

Lim, L. P., Lau, N. C., Garrett-Engele, P., Grimson, A., Schelter, J. M., Castle, J., Bartel, D. P., Linsley, P. S., & Johnson, J. M. (2005) · Nature

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 4,755

Function and Activation of NF-kappaB in the Immune System

Baeuerle, P. A., & Henkel, T. (1994) · Annual Review of Immunology

NF-κB Signaling PathwaysImmune Response and Inflammation

Cited by 4,745

Regulation of cancer cell metabolism

Cairns, R. A., Harris, I. S., & Mak, T. W. (2011) · Nature Reviews Cancer

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 4,744

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

Kozak, M. (1986) · Cell

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 4,741

MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

Rupaimoole, R., & Slack, F. J. (2017) · Nature Reviews Drug Discovery

MicroRNA in disease regulationRNA Interference and Gene Delivery

Cited by 4,741

DNA targeting specificity of RNA-guided Cas9 nucleases

Hsu, P. D., Scott, D. A., Weinstein, J. A., Ran, F. A., Konermann, S., Agarwala, V., Li, Y., Fine, E. J., Wu, X., Shalem, O., et al. (2013) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 4,741

HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing

Ivan, M., Kondo, K., Yang, H., Kim, W., Valiando, J., Ohh, M., Salic, A., Asara, J. M., Lane, W. S., & Kaelin Jr., W. G. (2001) · Science

Cancer, Hypoxia, and MetabolismUbiquitin and proteasome pathways

Cited by 4,735

Direct activation of calcium‐activated, phospholipid‐dependent protein kinase by tumor‐promoting phorbol esters

Castagna, M., Takai, Y., Kaibuchi, K., Sano, K., Kikkawa, U., & Nishizuka, Y. (1982) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingSphingolipid Metabolism and Signaling

Cited by 4,725

Gut microbiota in human metabolic health and disease

Fan, Y., & Pedersen, O. (2021) · Nature Reviews Microbiology

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 4,724

Photodynamic Therapy

Dougherty, T. J., Gomer, C. J., Henderson, B. W., Jori, G., Kessel, D., Korbelik, M., Moan, J., & Peng, Q. (1998) · JNCI Journal of the National Cancer Institute

Photodynamic Therapy Research StudiesNanoplatforms for cancer theranostics

Cited by 4,716

A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae

Uetz, P., Giot, L., Cagney, G., Mansfield, T. A., Judson, R. S., Knight, J. R., Lockshon, D., Narayan, V., Srinivasan, M., Pochart, P., et al. (2000) · Nature

Bioinformatics and Genomic NetworksFungal and yeast genetics research

Cited by 4,706

Phylogeny.fr: robust phylogenetic analysis for the non-specialist

Dereeper, A., Guignon, V., Blanc, G., Audic, S., Buffet, S., Chevenet, F., Dufayard, J.-F., Guindon, S., Lefort, V., Lescot, M., et al. (2008) · Nucleic Acids Research

Genomics and Phylogenetic StudiesGenetics, Bioinformatics, and Biomedical Research

Cited by 4,700

Metagenomic Analysis of the Human Distal Gut Microbiome

Gill, S. R., Pop, M., DeBoy, R. T., Eckburg, P. B., Turnbaugh, P. J., Samuel, B. S., Gordon, J. I., Relman, D. A., Fraser-Liggett, C. M., & Nelson, K. E. (2006) · Science

Gut microbiota and healthGenomics and Phylogenetic Studies

Cited by 4,699

In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro

Liang, C.-C., Park, A. Y., & Guan, J.-L. (2007) · Nature Protocols

Cellular Mechanics and InteractionsCell Image Analysis Techniques

Cited by 4,696

Dystrophin: the protein product of the Duchenne muscular dystrophy locus

Hoffman, E. P., Brown, R. H., & Kunkel, L. M. (1987) · Cell

Muscle Physiology and DisordersCardiomyopathy and Myosin Studies

Cited by 4,693

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

Davey Smith, G., & Hemani, G. (2014) · Human Molecular Genetics

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 4,677

Human DNA methylomes at base resolution show widespread epigenomic differences

Lister, R., Pelizzola, M., Dowen, R. H., Hawkins, R. D., Hon, G., Tonti-Filippini, J., Nery, J. R., Lee, L., Ye, Z., Ngo, Q.-M., et al. (2009) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 4,673

The widespread regulation of microRNA biogenesis, function and decay

Krol, J., Loedige, I., & Filipowicz, W. (2010) · Nature Reviews Genetics

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 4,672

mRNA vaccines — a new era in vaccinology

Pardi, N., Hogan, M. J., Porter, F. W., & Weissman, D. (2018) · Nature Reviews Drug Discovery

RNA Interference and Gene DeliveryImmunotherapy and Immune Responses

Cited by 4,667

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

Welsh, J. A., Goberdhan, D. C. I., O'Driscoll, L., Buzas, E. I., Blenkiron, C., Bussolati, B., Cai, H., Di Vizio, D., Driedonks, T. A. P., Erdbrügger, U., et al. (2024) · Journal of Extracellular Vesicles

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 4,663

Richness of human gut microbiome correlates with metabolic markers

Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J.-M., Kennedy, S., et al. (2013) · Nature

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 4,662

Cell Death

Danial, N. N., & Korsmeyer, S. J. (2004) · Cell

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 4,651

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

Doench, J. G., Fusi, N., Sullender, M., Hegde, M., Vaimberg, E. W., Donovan, K. F., Smith, I., Tothova, Z., Wilen, C., Orchard, R., et al. (2016) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 4,637

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

Wang, M., Carver, J. J., Phelan, V. V., Sanchez, L. M., Garg, N., Peng, Y., Nguyen, D. D., Watrous, J., Kapono, C. A., Luzzatto-Knaan, T., et al. (2016) · Nature Biotechnology

Metabolomics and Mass Spectrometry StudiesMass Spectrometry Techniques and Applications

Cited by 4,629