Most cited biochemistry, genetics and molecular biology papers
- Verified
AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR
Laskowski, R., Rullmann, J. A., MacArthur, M., Kaptein, R., & Thornton, J. (1996) · Journal of Biomolecular NMR
Protein Structure and DynamicsAdvanced NMR Techniques and Applications
Cited by 5,502
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The Inflammasomes
Schroder, K., & Tschopp, J. (2010) · Cell
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 5,475
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Molecular mechanisms and clinical applications of angiogenesis
Carmeliet, P., & Jain, R. K. (2011) · Nature
Angiogenesis and VEGF in CancerLymphatic System and Diseases
Cited by 5,467
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Regulation of microRNA biogenesis
Ha, M., & Kim, V. N. (2014) · Nature Reviews Molecular Cell Biology
MicroRNA in disease regulationRNA regulation and disease
Cited by 5,462
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Mutational heterogeneity in cancer and the search for new cancer-associated genes
Lawrence, M. S., Stojanov, P., Polak, P., Kryukov, G. V., Cibulskis, K., Sivachenko, A., Carter, S. L., Stewart, C., Mermel, C. H., Roberts, S. A., et al. (2013) · Nature
Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer
Cited by 5,461
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Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Trachootham, D., Alexandre, J., & Huang, P. (2009) · Nature Reviews Drug Discovery
Redox biology and oxidative stressCancer and biochemical research
Cited by 5,452
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RELION: Implementation of a Bayesian approach to cryo-EM structure determination
Scheres, S. H. W. (2012) · Journal of Structural Biology
Advanced Electron Microscopy Techniques and ApplicationsEnzyme Structure and Function
Cited by 5,446
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Stochastic Gene Expression in a Single Cell
Elowitz, M. B., Levine, A. J., Siggia, E. D., & Swain, P. S. (2002) · Science
Gene Regulatory Network Analysisstochastic dynamics and bifurcation
Cited by 5,441
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Oxidative stress, inflammation, and cancer: How are they linked?
Reuter, S., Gupta, S. C., Chaturvedi, M. M., & Aggarwal, B. B. (2010) · Free Radical Biology and Medicine
Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress
Cited by 5,441
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Base-Calling of Automated Sequencer Traces Using Phred. II. Error Probabilities
Ewing, B., & Green, P. (1998) · Genome Research
Genomics and Phylogenetic StudiesFractal and DNA sequence analysis
Cited by 5,439
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Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation.
Lacey, D. L., Timms, E., Tan, H.-L., Kelley, M. J., Dunstan, C. R., Burgess, T., Elliott, R., Colombero, A., Elliott, G., Scully, S., et al. (1998) · Cell
Bone Metabolism and DiseasesRheumatoid Arthritis Research and Therapies
Cited by 5,439
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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
Rogakou, E. P., Pilch, D. R., Orr, A. H., Ivanova, V. S., & Bonner, W. M. (1998) · Journal of Biological Chemistry
DNA Repair MechanismsEffects of Radiation Exposure
Cited by 5,438
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Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
Komor, A. C., Kim, Y. B., Packer, M. S., Zuris, J. A., & Liu, D. R. (2016) · Nature
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 5,437
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Revised Estimates for the Number of Human and Bacteria Cells in the Body
Sender, R., Fuchs, S., & Milo, R. (2016) · PLOS Biology
Gut microbiota and healthMicrobial Community Ecology and Physiology
Cited by 5,425
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The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T reg Cell Homeostasis
Smith, P. M., Howitt, M. R., Panikov, N., Michaud, M., Gallini, C. A., Bohlooly-Y, M., Glickman, J. N., & Garrett, W. S. (2013) · Science
Gut microbiota and healthT-cell and B-cell Immunology
Cited by 5,413
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Comparison of the predicted and observed secondary structure of T4 phage lysozyme
Matthews, B. W. (1975) · Biochimica et Biophysica Acta (BBA) - Protein Structure
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 5,399
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Regulation of the mevalonate pathway
Goldstein, J. L., & Brown, M. S. (1990) · Nature
Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism
Cited by 5,394
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Role of the microbiota in immunity and inflammation.
Belkaid, Y., & Hand, T. W. (2014) · Cell
Gut microbiota and healthImmune Response and Inflammation
Cited by 5,385
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Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
Zorov, D. B., Juhaszova, M., & Sollott, S. J. (2014) · Physiological Reviews
Mitochondrial Function and PathologyCell death mechanisms and regulation
Cited by 5,383
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Prions
Prusiner, S. B. (1998) · Proceedings of the National Academy of Sciences
Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments
Cited by 5,373
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Proposed minimum reporting standards for chemical analysis: Chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI)
Sumner, L. W., Amberg, A., Barrett, D., Beale, M. H., Beger, R., Daykin, C. A., Fan, T. W.-M., Fiehn, O., Goodacre, R., Griffin, J. L., et al. (2007) · Metabolomics
Metabolomics and Mass Spectrometry StudiesAdvanced Proteomics Techniques and Applications
Cited by 5,368
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A bivalent chromatin structure marks key developmental genes in embryonic stem cells
Bernstein, B. E., Mikkelsen, T. S., Xie, X., Kamal, M., Huebert, D. J., Cuff, J., Fry, B., Meissner, A., Wernig, M., Plath, K., et al. (2006) · Cell
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 5,361
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Inflamm‐aging: An Evolutionary Perspective on Immunosenescence
FRANCESCHI, C., BONAFÈ, M., VALENSIN, S., OLIVIERI, F., DE LUCA, M., OTTAVIANI, E., & DE BENEDICTIS, G. (2000) · Annals of the New York Academy of Sciences
Genetics, Aging, and Longevity in Model OrganismsImmune Response and Inflammation
Cited by 5,358
- Verified
Dimensionality reduction for visualizing single-cell data using UMAP
Becht, E., McInnes, L., Healy, J., Dutertre, C.-A., Kwok, I. W. H., Ng, L. G., Ginhoux, F., & Newell, E. W. (2019) · Nature Biotechnology
Single-cell and spatial transcriptomicsFace and Expression Recognition
Cited by 5,358
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