Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

The molecular biology of spindle assembly checkpoint signaling dynamics.

Musacchio, A. (2015) · Current Biology

Microtubule and mitosis dynamicsDNA Repair Mechanisms

Cited by 778

Prion-like transmission of protein aggregates in neurodegenerative diseases

Brundin, P., Melki, R., & Kopito, R. (2010) · Nature Reviews Molecular Cell Biology

Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments

Cited by 778

RELAX: Detecting Relaxed Selection in a Phylogenetic Framework

Wertheim, J. O., Murrell, B., Smith, M. D., Kosakovsky Pond, S. L., & Scheffler, K. (2015) · Molecular Biology and Evolution

Evolution and Genetic DynamicsGenomics and Phylogenetic Studies

Cited by 778

Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations

Butler, M. G., Dasouki, M. J., Zhou, X.-P., Talebizadeh, Z., Brown, M., Takahashi, T. N., Miles, J. H., Wang, C. H., Stratton, R., Pilarski, R., et al. (2005) · Journal of Medical Genetics

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 778

The inflammasome: an integrated view

Gross, O., Thomas, C. J., Guarda, G., & Tschopp, J. (2011) · Immunological Reviews

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 778

PPARs in Obesity-Induced T2DM, Dyslipidaemia and NAFLD

Gross, B., Pawlak, M., Lefebvre, P., & Staels, B. (2017) · Nature Reviews Endocrinology

Peroxisome Proliferator-Activated ReceptorsAdipokines, Inflammation, and Metabolic Diseases

Cited by 778

SCENIC+: single-cell multiomic inference of enhancers and gene regulatory networks

Bravo González-Blas, C., De Winter, S., Hulselmans, G., Hecker, N., Matetovici, I., Christiaens, V., Poovathingal, S., Wouters, J., Aibar, S., & Aerts, S. (2023) · Nature Methods

Genomics and Chromatin DynamicsSingle-cell and spatial transcriptomics

Cited by 778

Mesenchymal stromal cells: new directions

Keating, A. (2012) · Cell Stem Cell

Mesenchymal stem cell researchPeriodontal Regeneration and Treatments

Cited by 778

DNA methylation and body-mass index: a genome-wide analysis

Dick, K. J., Nelson, C. P., Tsaprouni, L., Sandling, J. K., Aïssi, D., Wahl, S., Meduri, E., Morange, P.-E., Gagnon, F., Grallert, H., et al. (2014) · The Lancet

Epigenetics and DNA MethylationGenetic Associations and Epidemiology

Cited by 778

The mTOR pathway in the control of protein synthesis

Wang, X., & Proud, C. G. (2006) · Physiology

PI3K/AKT/mTOR signaling in cancerMuscle metabolism and nutrition

Cited by 778

Gut Microbiome Metagenomics Analysis Suggests a Functional Model for the Development of Autoimmunity for Type 1 Diabetes

Brown, C. T., Davis-Richardson, A. G., Giongo, A., Gano, K. A., Crabb, D. B., Mukherjee, N., Casella, G., Drew, J. C., Ilonen, J., Knip, M., et al. (2011) · PLoS ONE

Gut microbiota and healthDiabetes and associated disorders

Cited by 778

Autophagy-dependent cell death

Denton, D., & Kumar, S. (2019) · Cell Death & Differentiation

Autophagy in Disease and TherapyCell death mechanisms and regulation

Cited by 777

Contractile properties of skeletal muscles from young, adult and aged mice.

Brooks, S. V., & Faulkner, J. A. (1988) · The Journal of Physiology

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 777

The Intestinal Microbiota in Colorectal Cancer.

Tilg, H., Adolph, T. E., Gerner, R. R., & Moschen, A. R. (2018) · Cancer Cell

Gut microbiota and healthColorectal Cancer Treatments and Studies

Cited by 777

Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis

Zhao, C., Irie, N., Takada, Y., Shimoda, K., Miyamoto, T., Nishiwaki, T., Suda, T., & Matsuo, K. (2006) · Cell Metabolism

Bone Metabolism and DiseasesAxon Guidance and Neuronal Signaling

Cited by 777

LC3 and GATE‐16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

Weidberg, H., Shvets, E., Shpilka, T., Shimron, F., Shinder, V., & Elazar, Z. (2010) · The EMBO Journal

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 777

Cisplatin Induces a Mitochondrial-ROS Response That Contributes to Cytotoxicity Depending on Mitochondrial Redox Status and Bioenergetic Functions

Marullo, R., Werner, E., Degtyareva, N., Moore, B., Altavilla, G., Ramalingam, S. S., & Doetsch, P. W. (2013) · PLoS ONE

Mitochondrial Function and PathologyMetal complexes synthesis and properties

Cited by 777

A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients

Hall, A. B., Yassour, M., Sauk, J., Garner, A., Jiang, X., Arthur, T., Lagoudas, G. K., Vatanen, T., Fornelos, N., Wilson, R., et al. (2017) · Genome Medicine

Gut microbiota and healthInflammatory Bowel Disease

Cited by 777

Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease

Kuscu, C., Arslan, S., Singh, R., Thorpe, J., & Adli, M. (2014) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 777

Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq

Jaitin, D. A., Weiner, A., Yofe, I., Lara-Astiaso, D., Keren-Shaul, H., David, E., Salame, T. M., Tanay, A., van Oudenaarden, A., & Amit, I. (2016) · Cell

Single-cell and spatial transcriptomicsCRISPR and Genetic Engineering

Cited by 777

Crystal structure of the human glucose transporter GLUT1

Deng, D., Xu, C., Sun, P., Wu, J., Yan, C., Hu, M., & Yan, N. (2014) · Nature

Enzyme Structure and FunctionMetabolism, Diabetes, and Cancer

Cited by 777

Human iPSC-based modeling of late-onset disease via progerin-induced aging

Miller, J. D., Ganat, Y. M., Kishinevsky, S., Bowman, R. L., Liu, B., Tu, E. Y., Mandal, P. K., Vera, E., Shim, J.-W., Kriks, S., et al. (2013) · Cell stem cell

Pluripotent Stem Cells ResearchParkinson's Disease Mechanisms and Treatments

Cited by 777

Intestinal Microbiota Composition Modulates Choline Bioavailability from Diet and Accumulation of the Proatherogenic Metabolite Trimethylamine- N -Oxide

Romano, K. A., Vivas, E. I., Amador-Noguez, D., & Rey, F. E. (2015) · mBio

Gut microbiota and healthAnimal Nutrition and Physiology

Cited by 777

Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta.

Postlethwaite, A. E., Keski-Oja, J., Moses, H. L., & Kang, A. H. (1987) · The Journal of experimental medicine

TGF-β signaling in diseasesLiver physiology and pathology

Cited by 777