Most cited biochemistry, genetics and molecular biology papers
- Verified
The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies
Zitvogel, L., Ma, Y., Raoult, D., Kroemer, G., & Gajewski, T. F. (2018) · Science
Gut microbiota and healthCancer Immunotherapy and Biomarkers
Cited by 777
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The RSK family of kinases: emerging roles in cellular signalling
Anjum, R., & Blenis, J. (2008) · Nature Reviews Molecular Cell Biology
Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways
Cited by 777
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Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases
Owens, D. M., & Keyse, S. M. (2007) · Oncogene
Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling
Cited by 777
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Markov state models of biomolecular conformational dynamics
Chodera, J. D., & Noé, F. (2014) · Current Opinion in Structural Biology
Protein Structure and DynamicsAdvanced Physical and Chemical Molecular Interactions
Cited by 776
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The Western Diet–Microbiome-Host Interaction and Its Role in Metabolic Disease
Zinöcker, M. K., & Lindseth, I. A. (2018) · Nutrients
Gut microbiota and healthNutritional Studies and Diet
Cited by 776
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A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells
Knutson, S. K., Wigle, T. J., Warholic, N. M., Sneeringer, C. J., Allain, C. J., Klaus, C. R., Sacks, J. D., Raimondi, A., Majer, C. R., Song, J., et al. (2012) · Nature Chemical Biology
Epigenetics and DNA MethylationCancer-related gene regulation
Cited by 776
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Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast
Dever, T. E., Feng, L., Wek, R. C., Cigan, A. M., Donahue, T. F., & Hinnebusch, A. G. (1992) · Cell
RNA and protein synthesis mechanismsFungal and yeast genetics research
Cited by 776
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Chemical biology of peroxynitrite: Kinetics, diffusion, and radicals
Ferrer-Sueta, G., & Radi, R. (2009) · ACS Chemical Biology
Redox biology and oxidative stressNitric Oxide and Endothelin Effects
Cited by 776
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Prion-like mechanisms in neurodegenerative diseases
Frost, B., & Diamond, M. I. (2010) · Nature Reviews Neuroscience
Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments
Cited by 776
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CRISPR-mediated direct mutation of cancer genes in the mouse liver
Xue, W., Chen, S., Yin, H., Tammela, T., Papagiannakopoulos, T., Joshi, N. S., Cai, W., Yang, G., Bronson, R., Crowley, D. G., et al. (2014) · Nature
CRISPR and Genetic EngineeringCancer Genomics and Diagnostics
Cited by 776
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The decline in skeletal muscle mass with aging is mainly attributed to a reduction in type II muscle fiber size
Nilwik, R., Snijders, T., Leenders, M., Groen, B. B. L., van Kranenburg, J., Verdijk, L. B., & van Loon, L. J. C. (2013) · Experimental Gerontology
Muscle Physiology and DisordersNutrition and Health in Aging
Cited by 776
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A practical approach to RT-qPCR—Publishing data that conform to the MIQE guidelines
Taylor, S., Wakem, M., Dijkman, G., Alsarraj, M., & Nguyen, M. (2010) · Methods
Molecular Biology Techniques and ApplicationsResearch Data Management Practices
Cited by 776
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Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
Yasuda, K., Miyake, K., Horikawa, Y., Hara, K., Osawa, H., Furuta, H., Hirota, Y., Mori, H., Jonsson, A., Sato, Y., et al. (2008) · Nature Genetics
Genetic Associations and EpidemiologyPancreatic function and diabetes
Cited by 776
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Imaging Dynamic Redox Changes in Mammalian Cells with Green Fluorescent Protein Indicators
Dooley, C. T., Dore, T. M., Hanson, G. T., Jackson, W. C., Remington, S. J., & Tsien, R. Y. (2004) · Journal of Biological Chemistry
Redox biology and oxidative stressAdvanced Fluorescence Microscopy Techniques
Cited by 776
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Chromatin state dynamics during blood formation
Lara-Astiaso, D., Weiner, A., Lorenzo-Vivas, E., Zaretsky, I., Jaitin, D. A., David, E., Keren-Shaul, H., Mildner, A., Winter, D., Jung, S., et al. (2014) · Science
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 776
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mTORC1 controls the adaptive transition of quiescent stem cells from G0 to GAlert
Rodgers, J. T., King, K. Y., Brett, J. O., Cromie, M. J., Charville, G. W., Maguire, K. K., Brunson, C., Mastey, N., Liu, L., Tsai, C.-R., et al. (2014) · Nature
Muscle Physiology and DisordersPI3K/AKT/mTOR signaling in cancer
Cited by 776
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Stress-activated cap’n’collar transcription factors in aging and human disease
Sykiotis, G. P., & Bohmann, D. (2010) · Science Signaling
Genomics, phytochemicals, and oxidative stressGenetics, Aging, and Longevity in Model Organisms
Cited by 776
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Tet1 and Tet2 Regulate 5-Hydroxymethylcytosine Production and Cell Lineage Specification in Mouse Embryonic Stem Cells
Koh, K. P., Yabuuchi, A., Rao, S., Huang, Y., Cunniff, K., Nardone, J., Laiho, A., Tahiliani, M., Sommer, C. A., Mostoslavsky, G., et al. (2011) · Cell Stem Cell
Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation
Cited by 776
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Colonic microbiome is altered in alcoholism
Mutlu, E. A., Gillevet, P. M., Rangwala, H., Sikaroodi, M., Naqvi, A., Engen, P. A., Kwasny, M., Lau, C. K., & Keshavarzian, A. (2012) · American Journal of Physiology-Gastrointestinal and Liver Physiology
Gut microbiota and healthAlcohol Consumption and Health Effects
Cited by 775
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In vivo genome-wide profiling of RNA secondary structure reveals novel regulatory features
Ding, Y., Tang, Y., Kwok, C. K., Zhang, Y., Bevilacqua, P. C., & Assmann, S. M. (2014) · Nature
RNA and protein synthesis mechanismsRNA Research and Splicing
Cited by 775
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Mechanisms and consequences of intestinal dysbiosis
Weiss, G. A., & Hennet, T. (2017) · Cellular and Molecular Life Sciences
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 775
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Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin.
Mizuno, A., Amizuka, N., Irie, K., Murakami, A., Fujise, N., Kanno, T., Sato, Y., Nakagawa, N., Yasuda, H., Mochizuki, S.-I., et al. (1998) · Biochemical and Biophysical Research Communications
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 775
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Antisense technology: an overview and prospectus
Crooke, S. T., Baker, B. F., Crooke, R. M., & Liang, X.-H. (2021) · Nature Reviews Drug Discovery
RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry
Cited by 775
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Evolution by gene loss
Albalat, R., & Cañestro, C. (2016) · Nature Reviews Genetics
Evolution and Genetic DynamicsChromosomal and Genetic Variations
Cited by 775
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