Most cited biochemistry, genetics and molecular biology papers
- Verified
HIF-2α Promotes Hypoxic Cell Proliferation by Enhancing c-Myc Transcriptional Activity
Gordan, J. D., Bertout, J. A., Hu, C.-J., Diehl, J. A., & Simon, M. C. (2007) · Cancer Cell
Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment
Cited by 781
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Measuring biological aging in humans: a quest
Ferrucci, L., Gonzalez‐Freire, M., Fabbri, E., Simonsick, E., Tanaka, T., Moore, Z., Salimi, S., Sierra, F., & de Cabo, R. (2020) · Aging Cell
Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence
Cited by 781
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Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT
Maltepe, E., Schmidt, J. V., Baunoch, D., Bradfield, C. A., & Simon, M. C. (1997) · Nature
Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism
Cited by 781
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Kv3 channels: voltage-gated K+ channels designed for high-frequency repetitive firing
Rudy, B., & McBain, C. J. (2001) · Trends in Neurosciences
Ion channel regulation and functionCardiac electrophysiology and arrhythmias
Cited by 781
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Broccoli: rapid selection of an RNA mimic of green fluorescent protein by fluorescence-based selection and directed evolution
Filonov, G. S., Moon, J. D., Svensen, N., & Jaffrey, S. R. (2014) · Journal of the American Chemical Society
RNA and protein synthesis mechanismsAdvanced biosensing and bioanalysis techniques
Cited by 780
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Pioneer Transcription Factors Target Partial DNA Motifs on Nucleosomes to Initiate Reprogramming
Soufi, A., Garcia, M. F., Jaroszewicz, A., Osman, N., Pellegrini, M., & Zaret, K. S. (2015) · Cell
Genomics and Chromatin DynamicsPluripotent Stem Cells Research
Cited by 780
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Alternative Splicing Regulatory Networks: Functions, Mechanisms, and Evolution
Ule, J., & Blencowe, B. J. (2019) · Molecular Cell
RNA Research and SplicingRNA regulation and disease
Cited by 780
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A common plan for dorsoventral patterning in Bilateria
De Robertis, E. M., & Sasai, Y. (1996) · Nature
Developmental Biology and Gene RegulationMarine Invertebrate Physiology and Ecology
Cited by 780
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Osteoclast–osteoblast communication
Matsuo, K., & Irie, N. (2008) · Archives of Biochemistry and Biophysics
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 780
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Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis
Nogueira, V., Park, Y., Chen, C.-C., Xu, P.-Z., Chen, M.-L., Tonic, I., Unterman, T., & Hay, N. (2008) · Cancer Cell
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 780
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PROVENGE (Sipuleucel-T) in Prostate Cancer: The First FDA-Approved Therapeutic Cancer Vaccine
Cheever, M. A., & Higano, C. S. (2011) · Clinical Cancer Research
Prostate Cancer Treatment and ResearchImmunotherapy and Immune Responses
Cited by 780
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Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteins
Taylor, S. J., Chae, H. Z., Rhee, S. G., & Exton, J. H. (1991) · Nature
Protein Kinase Regulation and GTPase SignalingReceptor Mechanisms and Signaling
Cited by 780
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Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR
Calkin, A. C., & Tontonoz, P. (2012) · Nature Reviews Molecular Cell Biology
Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms
Cited by 779
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The many substrates and functions of ATM.
Kastan, M. B., & Lim, D.-S. (2000) · Nature Reviews Molecular Cell Biology
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 779
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Post-translational disruption of dystroglycan–ligand interactions in congenital muscular dystrophies
Michele, D. E., Barresi, R., Kanagawa, M., Saito, F., Cohn, R. D., Satz, J. S., Dollar, J., Nishino, I., Kelley, R. I., Somer, H., et al. (2002) · Nature
Muscle Physiology and DisordersGlycosylation and Glycoproteins Research
Cited by 779
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Microbiota and Host Nutrition across Plant and Animal Kingdoms
Hacquard, S., Garrido-Oter, R., González, A., Spaepen, S., Ackermann, G., Lebeis, S., McHardy, A. C., Dangl, J. L., Knight, R., Ley, R., et al. (2015) · Cell Host & Microbe
Gut microbiota and healthPlant-Microbe Interactions and Immunity
Cited by 779
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Psychiatric Disorders From Childhood to Adulthood in 22q11.2 Deletion Syndrome: Results From the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome
Schneider, M., Debbané, M., Bassett, A. S., Chow, E. W. C., Fung, W. L. A., van den Bree, M. B. M., Owen, M., Murphy, K. C., Niarchou, M., Kates, W. R., et al. (2014) · American Journal of Psychiatry
Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment
Cited by 779
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UKPDS 25: autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes
Turner, R., Stratton, I., Horton, V., Manley, S., Zimmet, P., Mackay, I. R., Shattock, M., Bottazzo, G. F., & Holman, R. (1997) · The Lancet
Diabetes and associated disordersDiabetes Management and Research
Cited by 779
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The ADAMTS metalloproteinases
PORTER, S., CLARK, I. M., KEVORKIAN, L., & EDWARDS, D. R. (2005) · Biochemical Journal
Protease and Inhibitor MechanismsBlood Coagulation and Thrombosis Mechanisms
Cited by 779
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Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells
Zuin, J., Dixon, J. R., van der Reijden, M. I. J. A., Ye, Z., Kolovos, P., Brouwer, R. W. W., van de Corput, M. P. C., van de Werken, H. J. G., Knoch, T. A., van IJcken, W. F. J., et al. (2014) · Proceedings of the National Academy of Sciences
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 779
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Constraining the metabolic genotype–phenotype relationship using a phylogeny of in silico methods
Lewis, N. E., Nagarajan, H., & Palsson, B. O. (2012) · Nature Reviews Microbiology
Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis
Cited by 779
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Long-Range Charge Transfer in DNA: Transient Structural Distortions Control the Distance Dependence
Schuster, G. B. (2000) · Accounts of Chemical Research
DNA and Nucleic Acid ChemistryPhotochemistry and Electron Transfer Studies
Cited by 778
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The Interplay Between Mitochondrial Dynamics and Mitophagy
Twig, G., & Shirihai, O. S. (2011) · Antioxidants & Redox Signaling
Autophagy in Disease and TherapyMitochondrial Function and Pathology
Cited by 778
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Krüppel-like factor 4 regulates macrophage polarization
Liao, X., Sharma, N., Kapadia, F., Zhou, G., Lu, Y., Hong, H., Paruchuri, K., Mahabeleshwar, G. H., Dalmas, E., Venteclef, N., et al. (2011) · Journal of Clinical Investigation
Kruppel-like factors researchImmune cells in cancer
Cited by 778
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