Most cited biochemistry, genetics and molecular biology papers
- Verified
Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development
Baenke, F., Peck, B., Miess, H., & Schulze, A. (2013) · Disease Models & Mechanisms
Cancer, Lipids, and MetabolismLipid metabolism and biosynthesis
Cited by 772
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Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow
Bafico, A., Liu, G., Yaniv, A., Gazit, A., & Aaronson, S. A. (2001) · Nature Cell Biology
Wnt/β-catenin signaling in development and cancerHedgehog Signaling Pathway Studies
Cited by 772
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The lysosome: from waste bag to potential therapeutic target
Appelqvist, H., Wäster, P., Kågedal, K., & Öllinger, K. (2013) · Journal of Molecular Cell Biology
Autophagy in Disease and TherapyCellular transport and secretion
Cited by 772
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Spatial multi-omic map of human myocardial infarction
Kuppe, C., Ramirez Flores, R. O., Li, Z., Hayat, S., Levinson, R. T., Liao, X., Hannani, M. T., Tanevski, J., Wünnemann, F., Nagai, J. S., et al. (2022) · Nature
Single-cell and spatial transcriptomicsCongenital heart defects research
Cited by 772
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Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase
Gao, X., Wang, H., Yang, J. J., Liu, X., & Liu, Z.-R. (2012) · Molecular Cell
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 772
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Nucleotide Transformer: building and evaluating robust foundation models for human genomics
Dalla-Torre, H., Gonzalez, L., Mendoza-Revilla, J., Lopez Carranza, N., Grzywaczewski, A. H., Oteri, F., Dallago, C., Trop, E., de Almeida, B. P., Sirelkhatim, H., et al. (2025) · Nature Methods
Machine Learning in BioinformaticsGenetic Associations and Epidemiology
Cited by 772
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Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial
Vaidya, J. S., Joseph, D. J., Tobias, J. S., Bulsara, M., Wenz, F., Saunders, C., Alvarado, M., Flyger, H. L., Massarut, S., Eiermann, W., et al. (2010) · The Lancet
Breast Cancer Treatment StudiesAdvanced Radiotherapy Techniques
Cited by 772
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Alteration of gut microbiota in inflammatory bowel disease (IBD): cause or consequence? IBD treatment targeting the gut microbiome
Khan, I., Ullah, N., Zha, L., Bai, Y., Khan, A., Zhao, T., Che, T., & Zhang, C. (2019) · Pathogens
Gut microbiota and healthInflammatory Bowel Disease
Cited by 771
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The axonal transport of mitochondria
Hollenbeck, P. J., & Saxton, W. M. (2005) · Journal of Cell Science
Mitochondrial Function and PathologyMicrotubule and mitosis dynamics
Cited by 771
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Biogenesis and Function of Multivesicular Bodies
Piper, R. C., & Katzmann, D. J. (2007) · Annual Review of Cell and Developmental Biology
Cellular transport and secretionAutophagy in Disease and Therapy
Cited by 771
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Estimating African American Admixture Proportions by Use of Population-Specific Alleles
Parra, E. J., Marcini, A., Akey, J., Martinson, J., Batzer, M. A., Cooper, R., Forrester, T., Allison, D. B., Deka, R., Ferrell, R. E., et al. (1998) · The American Journal of Human Genetics
Forensic and Genetic ResearchRace, Genetics, and Society
Cited by 771
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SOST Is a Ligand for LRP5/LRP6 and a Wnt Signaling Inhibitor
Semënov, M., Tamai, K., & He, X. (2005) · Journal of Biological Chemistry
Wnt/β-catenin signaling in development and cancerBone Metabolism and Diseases
Cited by 771
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Toward Minimal Residual Disease-Directed Therapy in Melanoma
Rambow, F., Rogiers, A., Marin-Bejar, O., Aibar, S., Femel, J., Dewaele, M., Karras, P., Brown, D., Chang, Y. H., Debiec-Rychter, M., et al. (2018) · Cell
Melanoma and MAPK PathwaysCancer Cells and Metastasis
Cited by 771
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Kinesin hydrolyses one ATP per 8-nm step
Schnitzer, M. J., & Block, S. M. (1997) · Nature
Microtubule and mitosis dynamicsForce Microscopy Techniques and Applications
Cited by 771
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Acid-Mediated Tumor Invasion: a Multidisciplinary Study
Gatenby, R. A., Gawlinski, E. T., Gmitro, A. F., Kaylor, B., & Gillies, R. J. (2006) · Cancer Research
Cancer, Hypoxia, and MetabolismMathematical Biology Tumor Growth
Cited by 771
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Reversible Ponceau staining as a loading control alternative to actin in Western blots
Romero-Calvo, I., Ocón, B., Martínez-Moya, P., Suárez, M. D., Zarzuelo, A., Martínez-Augustin, O., & de Medina, F. S. (2010) · Analytical Biochemistry
Molecular Biology Techniques and ApplicationsAdvanced Proteomics Techniques and Applications
Cited by 771
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Three proteins define a class of human histone deacetylases related to yeast Hda1p
Grozinger, C. M., Hassig, C. A., & Schreiber, S. L. (1999) · Proceedings of the National Academy of Sciences
Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics
Cited by 770
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Immune-mediated eradication of tumors through the blockade of transforming growth factor-β signaling in T cells
Gorelik, L., & Flavell, R. A. (2001) · Nature Medicine
TGF-β signaling in diseasesT-cell and B-cell Immunology
Cited by 770
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Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans
Palikaras, K., Lionaki, E., & Tavernarakis, N. (2015) · Nature
Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms
Cited by 770
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Coexpression Analysis of Human Genes Across Many Microarray Data Sets
Lee, H. K., Hsu, A. K., Sajdak, J., Qin, J., & Pavlidis, P. (2004) · Genome Research
Bioinformatics and Genomic NetworksGene expression and cancer classification
Cited by 770
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Bias, robustness and scalability in single-cell differential expression analysis
Soneson, C., & Robinson, M. D. (2018) · Nature Methods
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 770
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Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins
Wilhelm, B. G., Mandad, S., Truckenbrodt, S., Kröhnert, K., Schäfer, C., Rammner, B., Koo, S. J., Claßen, G. A., Krauss, M., Haucke, V., et al. (2014) · Science
Cellular transport and secretionNeuroscience and Neuropharmacology Research
Cited by 770
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Universal rules and idiosyncratic features in tRNA identity
Giege, R., Sissler, M., & Florentz, C. (1998) · Nucleic Acids Research
RNA and protein synthesis mechanismsRNA modifications and cancer
Cited by 769
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Nicotine activates and desensitizes midbrain dopamine neurons
Pidoplichko, V. I., DeBiasi, M., Williams, J. T., & Dani, J. A. (1997) · Nature
Nicotinic Acetylcholine Receptors StudySmoking Behavior and Cessation
Cited by 769
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