Most cited biochemistry, genetics and molecular biology papers
- Verified
Inflammatory bowel diseases (IBD) and the microbiome-searching the crime scene for clues
Lee, M., & Chang, E. B. (2021) · Gastroenterology
Gut microbiota and healthInflammatory Bowel Disease
Cited by 645
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Mitochondrial metabolism promotes adaptation to proteotoxic stress
Tsvetkov, P., Detappe, A., Cai, K., Keys, H. R., Brune, Z., Ying, W., Thiru, P., Reidy, M., Kugener, G., Rossen, J., et al. (2019) · Nature Chemical Biology
Ubiquitin and proteasome pathwaysCell death mechanisms and regulation
Cited by 645
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Endogenous siRNAs Derived from Transposons and mRNAs in Drosophila Somatic Cells
Ghildiyal, M., Seitz, H., Horwich, M. D., Li, C., Du, T., Lee, S., Xu, J., Kittler, E. L. W., Zapp, M. L., Weng, Z., et al. (2008) · Science
Chromosomal and Genetic VariationsRNA Interference and Gene Delivery
Cited by 645
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Resistant Starches Types 2 and 4 Have Differential Effects on the Composition of the Fecal Microbiota in Human Subjects
Martínez, I., Kim, J., Duffy, P. R., Schlegel, V. L., & Walter, J. (2010) · PLoS ONE
Gut microbiota and healthFood composition and properties
Cited by 645
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A guide to assessing cellular senescence in vitro and in vivo
González‐Gualda, E., Baker, A. G., Fruk, L., & Muñoz‐Espín, D. (2021) · The FEBS Journal
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 645
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Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells
Csak, T., Ganz, M., Pespisa, J., Kodys, K., Dolganiuc, A., & Szabo, G. (2011) · Hepatology
Inflammasome and immune disordersLiver Disease Diagnosis and Treatment
Cited by 645
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A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: A strategy for overcoming the PEG dilemma
Hatakeyama, H., Akita, H., & Harashima, H. (2011) · Advanced Drug Delivery Reviews
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 645
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More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance
Lukas, J., Lukas, C., & Bartek, J. (2011) · Nature Cell Biology
DNA Repair MechanismsGenomics and Chromatin Dynamics
Cited by 645
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Multicenter Phase II Study of the Oral MEK Inhibitor, CI-1040, in Patients With Advanced Non-Small-Cell Lung, Breast, Colon, and Pancreatic Cancer
Rinehart, J., Adjei, A. A., LoRusso, P. M., Waterhouse, D., Hecht, J. R., Natale, R. B., Hamid, O., Varterasian, M., Asbury, P., Kaldjian, E. P., et al. (2004) · Journal of Clinical Oncology
Melanoma and MAPK PathwaysColorectal Cancer Treatments and Studies
Cited by 645
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ATP synthesis and storage
Bonora, M., Patergnani, S., Rimessi, A., De Marchi, E., Suski, J. M., Bononi, A., Giorgi, C., Marchi, S., Missiroli, S., Poletti, F., et al. (2012) · Purinergic Signalling
Adenosine and Purinergic SignalingATP Synthase and ATPases Research
Cited by 644
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Role of peroxisomes in ros/rns-metabolism: Implications for human disease
Fransen, M., Nordgren, M., Wang, B., & Apanasets, O. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress
Cited by 644
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Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation
Weiler, I. J., Irwin, S. A., Klintsova, A. Y., Spencer, C. M., Brazelton, A. D., Miyashiro, K., Comery, T. A., Patel, B., Eberwine, J., & Greenough, W. T. (1997) · Proceedings of the National Academy of Sciences
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 644
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Genetic variability in the regulation of gene expression in ten regions of the human brain
UK Brain Expression Consortium, Ramasamy, A., North American Brain Expression Consortium, Trabzuni, D., Guelfi, S., Varghese, V., Smith, C., Walker, R., De, T., Coin, L., et al. (2014) · Nature Neuroscience
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 644
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Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat
Castano, L., & Eisenbarth, G. S. (1990) · Annual Review of Immunology
Diabetes and associated disordersT-cell and B-cell Immunology
Cited by 644
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LKB1 and AMP-activated protein kinase control of mTOR signalling and growth
Shaw, R. J. (2009) · Acta Physiologica
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 644
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Inhibition of protein kinase C μ by various inhibitors. Inhibition from protein kinase c isoenzymes
Gschwendt, M., Dieterich, S., Rennecke, J., Kittstein, W., Mueller, H.-J., & Johannes, F.-J. (1996) · FEBS Letters
Protein Kinase Regulation and GTPase SignalingSignaling Pathways in Disease
Cited by 644
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Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017α and P450 aromatase localized in neurons
Hojo, Y., Hattori, T.-A., Enami, T., Furukawa, A., Suzuki, K., Ishii, H.-T., Mukai, H., Morrison, J. H., Janssen, W. G. M., Kominami, S., et al. (2004) · Proceedings of the National Academy of Sciences
Estrogen and related hormone effectsSteroid Chemistry and Biochemistry
Cited by 644
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Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing
Atcha, H., Jairaman, A., Holt, J. R., Meli, V. S., Nagalla, R. R., Veerasubramanian, P. K., Brumm, K. T., Lim, H. E., Othy, S., Cahalan, M. D., et al. (2021) · Nature Communications
Cellular Mechanics and InteractionsIon Channels and Receptors
Cited by 644
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Low-dose metformin targets the lysosomal AMPK pathway through PEN2
Ma, T., Tian, X., Zhang, B., Li, M., Wang, Y., Yang, C., Wu, J., Wei, X., Qu, Q., Yu, Y., et al. (2022) · Nature
Metabolism, Diabetes, and CancerAutophagy in Disease and Therapy
Cited by 644
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MULTILOCUS STRUCTURE OF NATURAL POPULATIONS OF HORDEUM SPONTANEUM
Brown, A. H. D., Feldman, M. W., & Nevo, E. (1980) · Genetics
Genetic diversity and population structureWheat and Barley Genetics and Pathology
Cited by 643
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Systematic mapping of functional enhancer–promoter connections with CRISPR interference
Fulco, C. P., Munschauer, M., Anyoha, R., Munson, G., Grossman, S. R., Perez, E. M., Kane, M., Cleary, B., Lander, E. S., & Engreitz, J. M. (2016) · Science
Genomics and Chromatin DynamicsCRISPR and Genetic Engineering
Cited by 643
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Two neurons mediate diet-restriction-induced longevity in C. elegans
Bishop, N. A., & Guarente, L. (2007) · Nature
Genetics, Aging, and Longevity in Model OrganismsNeurobiology and Insect Physiology Research
Cited by 643
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Loss of epigenetic information as a cause of mammalian aging
Yang, J.-H., Hayano, M., Griffin, P. T., Amorim, J. A., Bonkowski, M. S., Apostolides, J. K., Salfati, E. L., Blanchette, M., Munding, E. M., Bhakta, M., et al. (2023) · Cell
Genetics, Aging, and Longevity in Model OrganismsEpigenetics and DNA Methylation
Cited by 643
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NONCODE 2016: an informative and valuable data source of long non-coding RNAs
Zhao, Y., Li, H., Fang, S., Kang, Y., wu, W., Hao, Y., Li, Z., Bu, D., Sun, N., Zhang, M. Q., et al. (2016) · Nucleic Acids Research
Cancer-related molecular mechanisms researchGenomics and Phylogenetic Studies
Cited by 643
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