Most cited biochemistry, genetics and molecular biology papers
- Verified
Enhancer redundancy provides phenotypic robustness in mammalian development
Osterwalder, M., Barozzi, I., Tissières, V., Fukuda-Yuzawa, Y., Mannion, B. J., Afzal, S. Y., Lee, E. A., Zhu, Y., Plajzer-Frick, I., Pickle, C. S., et al. (2018) · Nature
Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation
Cited by 642
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Molecular Mechanisms of Mammalian Global Genome Nucleotide Excision Repair
Gillet, L. C. J., & Schärer, O. D. (2006) · Chemical Reviews
DNA Repair MechanismsDNA and Nucleic Acid Chemistry
Cited by 642
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Cytokine profile of human adipose-derived stem cells: expression of angiogenic, hematopoietic, and pro-inflammatory factors
Kilroy, G. E., Foster, S. J., Wu, X., Ruiz, J., Sherwood, S., Heifetz, A., Ludlow, J. W., Stricker, D. M., Potiny, S., Green, P., et al. (2007) · Journal of Cellular Physiology
Mesenchymal stem cell researchAdipokines, Inflammation, and Metabolic Diseases
Cited by 642
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Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans
Bamberger, C. M., Bamberger, A. M., de Castro, M., & Chrousos, G. P. (1995) · Journal of Clinical Investigation
Estrogen and related hormone effectsAdrenal Hormones and Disorders
Cited by 642
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JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation.
Kallunki, T., Su, B., Tsigelny, I., Sluss, H. K., Dérijard, B., Moore, G., Davis, R., & Karin, M. (1994) · Genes & Development
Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases
Cited by 642
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Primary Cilia and Mammalian Hedgehog Signaling
Bangs, F., & Anderson, K. V. (2017) · Cold Spring Harbor Perspectives in Biology
Genetic and Kidney Cyst DiseasesHedgehog Signaling Pathway Studies
Cited by 642
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Lecticans: organizers of the brain extracellular matrix
Yamaguchi, Y. (2000) · Cellular and Molecular Life Sciences
Proteoglycans and glycosaminoglycans researchGlycosylation and Glycoproteins Research
Cited by 642
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Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naive Parkinson's disease patients
Bedarf, J. R., Hildebrand, F., Coelho, L. P., Sunagawa, S., Bahram, M., Goeser, F., Bork, P., & Wüllner, U. (2017) · Genome Medicine
Gut microbiota and healthParkinson's Disease Mechanisms and Treatments
Cited by 642
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Myogenic Vector Expression of Insulin-like Growth Factor I Stimulates Muscle Cell Differentiation and Myofiber Hypertrophy in Transgenic Mice
Coleman, M. E., DeMayo, F., Yin, K. C., Lee, H. M., Geske, R., Montgomery, C., & Schwartz, R. J. (1995) · Journal of Biological Chemistry
Muscle Physiology and DisordersGrowth Hormone and Insulin-like Growth Factors
Cited by 642
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microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer
Braconi, C., Kogure, T., Valeri, N., Huang, N., Nuovo, G., Costinean, S., Negrini, M., Miotto, E., Croce, C. M., & Patel, T. (2011) · Oncogene
Cancer-related molecular mechanisms researchMicroRNA in disease regulation
Cited by 642
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Haplotype blocks and linkage disequilibrium in the human genome
Wall, J. D., & Pritchard, J. K. (2003) · Nature Reviews Genetics
Genetic Associations and EpidemiologyForensic and Genetic Research
Cited by 642
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Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.
Chen, Q., & Ames, B. N. (1994) · Proceedings of the National Academy of Sciences
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 641
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Enzyme promiscuity: evolutionary and mechanistic aspects
Khersonsky, O., Roodveldt, C., & Tawfik, D. S. (2006) · Current Opinion in Chemical Biology
Evolution and Genetic DynamicsProtein Structure and Dynamics
Cited by 641
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Mechanisms of p53-dependent apoptosis
Schuler, M., & Green, D. R. (2001) · Biochemical Society Transactions
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 641
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Gene targeting using zinc finger nucleases
Porteus, M. H., & Carroll, D. (2005) · Nature Biotechnology
CRISPR and Genetic EngineeringRNA Interference and Gene Delivery
Cited by 641
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CTCF Binding Polarity Determines Chromatin Looping
de Wit, E., Vos, E. S. M., Holwerda, S. J. B., Valdes-Quezada, C., Verstegen, M. J. A. M., Teunissen, H., Splinter, E., Wijchers, P. J., Krijger, P. H. L., & de Laat, W. (2015) · Molecular Cell
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 641
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Direct small-molecule inhibitors of KRAS: from structural insights to mechanism-based design
Ostrem, J. M. L., & Shokat, K. M. (2016) · Nature Reviews Drug Discovery
Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases
Cited by 641
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Insights into the role of the microbiome in obesity and type 2 diabetes
Hartstra, A. V., Bouter, K. E. C., Bäckhed, F., & Nieuwdorp, M. (2015) · Diabetes Care
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 641
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Discovery and Characterization of Field Resistance to Bt Maize: Spodoptera frugiperda (Lepidoptera: Noctuidae) in Puerto Rico
Storer, N. P., Babcock, J. M., Schlenz, M., Meade, T., Thompson, G. D., Bing, J. W., & Huckaba, R. M. (2010) · Journal of Economic Entomology
Insect Resistance and GeneticsGenetically Modified Organisms Research
Cited by 641
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Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors
Negre‐Salvayre, A., Coatrieux, C., Ingueneau, C., & Salvayre, R. (2008) · British Journal of Pharmacology
Advanced Glycation End Products researchAntioxidant Activity and Oxidative Stress
Cited by 641
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Developmental enhancers and chromosome topology
Furlong, E. E. M., & Levine, M. (2018) · Science
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 641
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The Fate of Mutations Surfing on the Wave of a Range Expansion
Klopfstein, S., Currat, M., & Excoffier, L. (2006) · Molecular Biology and Evolution
Evolution and Genetic DynamicsGenetic diversity and population structure
Cited by 641
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The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein.
Siomi, H., Siomi, M. C., Nussbaum, R. L., & Dreyfuss, G. (1993) · Cell
Genetics and Neurodevelopmental DisordersRNA Research and Splicing
Cited by 641
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DeepCRISPR: Optimized CRISPR guide RNA design by deep learning
Chuai, G., Ma, H., Yan, J., Chen, M., Hong, N., Xue, D., Zhou, C., Zhu, C., Chen, K., Duan, B., et al. (2018) · Genome biology
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 641
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