Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

The Genetic Basis of Mendelian Phenotypes: Discoveries, Challenges, and Opportunities

Chong, J. X., Buckingham, K. J., Jhangiani, S. N., Boehm, C., Sobreira, N., Smith, J. D., Harrell, T. M., McMillin, M. J., Wiszniewski, W., Gambin, T., et al. (2015) · The American Journal of Human Genetics

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 643

Mutation as a Stress Response and the Regulation of Evolvability

Galhardo, R. S., Hastings, P. J., & Rosenberg, S. M. (2007) · Critical Reviews in Biochemistry and Molecular Biology

Evolution and Genetic DynamicsDNA Repair Mechanisms

Cited by 643

Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer’s disease

Morabito, S., Miyoshi, E., Michael, N., Shahin, S., Martini, A. C., Head, E., Silva, J., Leavy, K., Perez-Rosendahl, M., & Swarup, V. (2021) · Nature Genetics

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 643

Negative feedback and ultrasensitivity can bring about oscillations in the mitogen‐activated protein kinase cascades

Kholodenko, B. N. (2000) · European Journal of Biochemistry

Gene Regulatory Network AnalysisProtein Kinase Regulation and GTPase Signaling

Cited by 643

Oxidation of nitrogen-oxides by bound dioxygen in hemoproteins

Doyle, M. P., & Hoekstra, J. W. (1981) · Journal of Inorganic Biochemistry

Hemoglobin structure and functionMetal-Catalyzed Oxygenation Mechanisms

Cited by 643

Quality and efficiency assessment of six extracellular vesicle isolation methods by nano-flow cytometry

Tian, Y., Gong, M., Hu, Y., Liu, H., Zhang, W., Zhang, M., Hu, X., Aubert, D., Zhu, S., Wu, L., et al. (2020) · Journal of Extracellular Vesicles

Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery

Cited by 643

The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans

Apfeld, J., O'Connor, G., McDonagh, T., DiStefano, P. S., & Curtis, R. (2004) · Genes & Development

Genetics, Aging, and Longevity in Model OrganismsMetabolism, Diabetes, and Cancer

Cited by 643

Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene.

James, T. C., & Elgin, S. C. (1986) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 643

Functional and evolutionary implications of gene orthology

Gabaldón, T., & Koonin, E. V. (2013) · Nature Reviews Genetics

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 643

M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon Cancer

Lan, J., Sun, L., Xu, F., Liu, L., Hu, F., Song, D., Hou, Z., Wu, W., Luo, X., Wang, J., et al. (2019) · Cancer Research

Extracellular vesicles in diseaseImmune cells in cancer

Cited by 643

The Biogenesis of Nascent Circular RNAs

Zhang, Y., Xue, W., Li, X., Zhang, J., Chen, S., Zhang, J.-L., Yang, L., & Chen, L.-L. (2016) · Cell Reports

Circular RNAs in diseasesRNA Research and Splicing

Cited by 643

Glycomics Hits the Big Time

Hart, G. W., & Copeland, R. J. (2010) · Cell

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 643

MULTI-seq: sample multiplexing for single-cell RNA sequencing using lipid-tagged indices

McGinnis, C. S., Patterson, D. M., Winkler, J., Conrad, D. N., Hein, M. Y., Srivastava, V., Hu, J. L., Murrow, L. M., Weissman, J. S., Werb, Z., et al. (2019) · Nature Methods

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 643

Sex steroid deficiency-associated bone loss is microbiota dependent and prevented by probiotics

Li, J.-Y., Chassaing, B., Tyagi, A. M., Vaccaro, C., Luo, T., Adams, J., Darby, T. M., Weitzmann, M. N., Mulle, J. G., Gewirtz, A. T., et al. (2016) · Journal of Clinical Investigation

Gut microbiota and healthBone Metabolism and Diseases

Cited by 643

In search of the tumour-suppressor functions of BRCA1 and BRCA2

Scully, R., & Livingston, D. M. (2000) · Nature

BRCA gene mutations in cancerDNA Repair Mechanisms

Cited by 643

Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer

Reid, S., Schindler, D., Hanenberg, H., Barker, K., Hanks, S., Kalb, R., Neveling, K., Kelly, P., Seal, S., Freund, M., et al. (2007) · Nature Genetics

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 642

Impaired aryl hydrocarbon receptor ligand production by the gut microbiota is a key factor in metabolic syndrome

Natividad, J. M., Agus, A., Planchais, J., Lamas, B., Jarry, A. C., Martin, R., Michel, M.-L., Chong-Nguyen, C., Roussel, R., Straube, M., et al. (2018) · Cell Metabolism

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 642

The MAP kinase signaling cascades: a system of hundreds of components regulates a diverse array of physiological functions

Keshet, Y., & Seger, R. (2010) · Methods in Molecular Biology

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

Cited by 642

The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase

Hiratsuka, S., Watanabe, A., Sakurai, Y., Akashi-Takamura, S., Ishibashi, S., Miyake, K., Shibuya, M., Akira, S., Aburatani, H., & Maru, Y. (2008) · Nature Cell Biology

S100 Proteins and AnnexinsChemokine receptors and signaling

Cited by 642

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

C Reactive Protein Coronary Heart Disease Genetics Collaboration (CCGC) (2011) · BMJ

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 642

Stool microbiome and metabolome differences between colorectal cancer patients and healthy adults

Weir, T. L., Manter, D. K., Sheflin, A. M., Barnett, B. A., Heuberger, A. L., & Ryan, E. P. (2013) · PLoS ONE

Gut microbiota and healthMetabolomics and Mass Spectrometry Studies

Cited by 642

Senescence impairs successful reprogramming to pluripotent stem cells

Banito, A., Rashid, S. T., Acosta, J. C., Li, S., Pereira, C. F., Geti, I., Pinho, S., Silva, J. C., Azuara, V., Walsh, M., et al. (2009) · Genes & Development

Pluripotent Stem Cells ResearchTelomeres, Telomerase, and Senescence

Cited by 642

The high-affinity HSP90–CHIP complex recognizes and selectively degrades phosphorylated tau client proteins

Dickey, C. A., Kamal, A., Lundgren, K., Klosak, N., Bailey, R. M., Dunmore, J., Ash, P., Shoraka, S., Zlatkovic, J., Eckman, C. B., et al. (2007) · Journal of Clinical Investigation

Heat shock proteins researchAlzheimer's disease research and treatments

Cited by 642

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

Maejima, I., Takahashi, A., Omori, H., Kimura, T., Takabatake, Y., Saitoh, T., Yamamoto, A., Hamasaki, M., Noda, T., Isaka, Y., et al. (2013) · The EMBO Journal

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 642