Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures.

Borkovich, K. A., Farrelly, F. W., Finkelstein, D. B., Taulien, J., & Lindquist, S. (1989) · Molecular and Cellular Biology

Heat shock proteins researchFungal and yeast genetics research

Cited by 641

Mechanical regulation of bone remodeling

Wang, L., You, X., Zhang, L., Zhang, C., & Zou, W. (2022) · Bone Research

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 641

PPAR : a dagger in the heart of the metabolic syndrome

Barish, G. D. (2006) · Journal of Clinical Investigation

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 641

The contributory role of gut microbiota in cardiovascular disease

Tang, W. H. W., & Hazen, S. L. (2014) · Journal of Clinical Investigation

Gut microbiota and healthNutritional Studies and Diet

Cited by 641

An Efficient Chromatin Immunoprecipitation (ChIP) Protocol for Studying Histone Modifications in Arabidopsis Plants

Saleh, A., Alvarez-Venegas, R., & Avramova, Z. (2008) · Nature Protocols

Genomics and Chromatin DynamicsPlant Molecular Biology Research

Cited by 641

Amino acids rather than glucose account for the majority of cell mass in proliferating mammalian cells

Hosios, A. M., Hecht, V. C., Danai, L. V., Johnson, M. O., Rathmell, J. C., Steinhauser, M. L., Manalis, S. R., & Vander Heiden, M. G. (2016) · Developmental Cell

Cancer, Hypoxia, and MetabolismPI3K/AKT/mTOR signaling in cancer

Cited by 641

Temporal control of puffing activity in polytene chromosomes

Ashburner, M., Chihara, C., Meltzer, P., & Richards, G. (1974) · Cold Spring Harbor Symposia on Quantitative Biology

Genomics and Chromatin DynamicsChromosomal and Genetic Variations

Cited by 641

AAV Vector Immunogenicity in Humans: A Long Journey to Successful Gene Transfer

Costa Verdera, H., Kuranda, K., & Mingozzi, F. (2020) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 641

Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat

Park, T. J., Reznick, J., Peterson, B. L., Blass, G., Omerbašić, D., Bennett, N. C., Kuich, P. H. J. L., Zasada, C., Browe, B. M., Hamann, W., et al. (2017) · Science

Cancer, Hypoxia, and MetabolismPhysiological and biochemical adaptations

Cited by 641

CADD-Splice—improving genome-wide variant effect prediction using deep learning-derived splice scores

Rentzsch, P., Schubach, M., Shendure, J., & Kircher, M. (2021) · Genome Medicine

Genomics and Rare DiseasesRNA Research and Splicing

Cited by 640

Principles of DNA methylation and their implications for biology and medicine

Dor, Y., & Cedar, H. (2018) · The Lancet

Epigenetics and DNA MethylationGenetic Syndromes and Imprinting

Cited by 640

Protein Kinase C as a Molecular Machine for Decoding Calcium and Diacylglycerol Signals

Oancea, E., & Meyer, T. (1998) · Cell

Protein Kinase Regulation and GTPase SignalingCalcium signaling and nucleotide metabolism

Cited by 640

MEK162 for patients with advanced melanoma harbouring NRAS or Val600 BRAF mutations: a non-randomised, open-label phase 2 study.

Ascierto, P. A., Schadendorf, D., Berking, C., Agarwala, S. S., van Herpen, C. M., Queirolo, P., Blank, C. U., Hauschild, A., Beck, J. T., St-Pierre, A., et al. (2013) · The Lancet Oncology

Melanoma and MAPK PathwaysCutaneous Melanoma Detection and Management

Cited by 640

In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system

Maddalo, D., Manchado, E., Concepcion, C. P., Bonetti, C., Vidigal, J. A., Han, Y.-C., Ogrodowski, P., Crippa, A., Rekhtman, N., de Stanchina, E., et al. (2014) · Nature

CRISPR and Genetic EngineeringCancer Genomics and Diagnostics

Cited by 640

The TEAD/TEF Family Protein Scalloped Mediates Transcriptional Output of the Hippo Growth-Regulatory Pathway

Wu, S., Liu, Y., Zheng, Y., Dong, J., & Pan, D. (2008) · Developmental Cell

Hippo pathway signaling and YAP/TAZDevelopmental Biology and Gene Regulation

Cited by 640

Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin.

Chou, C. K., Dull, T. J., Russell, D. S., Gherzi, R., Lebwohl, D., Ullrich, A., & Rosen, O. M. (1987) · Journal of Biological Chemistry

Metabolism, Diabetes, and CancerProtein Kinase Regulation and GTPase Signaling

Cited by 640

Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

Bentzinger, C. F., Romanino, K., Cloëtta, D., Lin, S., Mascarenhas, J. B., Oliveri, F., Xia, J., Casanova, E., Costa, C. F., Brink, M., et al. (2008) · Cell Metabolism

Muscle Physiology and DisordersPI3K/AKT/mTOR signaling in cancer

Cited by 640

The Evolution of Animal Domestication

Larson, G., & Fuller, D. Q. (2014) · Annual Review of Ecology, Evolution, and Systematics

Genetic and phenotypic traits in livestockHuman-Animal Interaction Studies

Cited by 640

DNA double-strand break repair: From mechanistic understanding to cancer treatment

HELLEDAY, T., LO, J., VANGENT, D., & ENGELWARD, B. (2007) · DNA Repair

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 640

Tobacco-smoking-related differential DNA methylation: 27K discovery and replication

Breitling, L. P., Yang, R., Korn, B., Burwinkel, B., & Brenner, H. (2011) · The American Journal of Human Genetics

Epigenetics and DNA MethylationSmoking Behavior and Cessation

Cited by 640

destiny : diffusion maps for large-scale single-cell data in R

Angerer, P., Haghverdi, L., Büttner, M., Theis, F. J., Marr, C., & Buettner, F. (2016) · Bioinformatics

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 640

Inflammation as a Tumor Promoter in Cancer Induction

Philip, M., Rowley, D. A., & Schreiber, H. (2004) · Seminars in Cancer Biology

NF-κB Signaling PathwaysImmune cells in cancer

Cited by 640

Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the xc− cystine transporter: a new action for an old drug

Gout, P., Buckley, A., Simms, C., & Bruchovsky, N. (2001) · Leukemia

Amino Acid Enzymes and MetabolismSulfur Compounds in Biology

Cited by 640

Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine

Huang, Z.-L., Qu, W.-M., Eguchi, N., Chen, J.-F., Schwarzschild, M. A., Fredholm, B. B., Urade, Y., & Hayaishi, O. (2005) · Nature Neuroscience

Adenosine and Purinergic SignalingCoffee research and impacts

Cited by 640