Most cited biochemistry, genetics and molecular biology papers
- Verified
Peroxisome Proliferator-activated Receptor α Activators Improve Insulin Sensitivity and Reduce Adiposity
Guerre-Millo, M., Gervois, P., Raspé, E., Madsen, L., Poulain, P., Derudas, B., Herbert, J.-M., Winegar, D. A., Willson, T. M., Fruchart, J.-C., et al. (2000) · Journal of Biological Chemistry
Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism
Cited by 605
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A Higher Mutational Burden in Females Supports a “Female Protective Model” in Neurodevelopmental Disorders
Jacquemont, S., Coe, B. P., Hersch, M., Duyzend, M. H., Krumm, N., Bergmann, S., Beckmann, J. S., Rosenfeld, J. A., & Eichler, E. E. (2014) · The American Journal of Human Genetics
Genetics and Neurodevelopmental DisordersGenomic variations and chromosomal abnormalities
Cited by 605
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Diagnostic genome profiling in mental retardation
de Vries, B. B. A., Pfundt, R., Leisink, M., Koolen, D. A., Vissers, L. E. L. M., Janssen, I. M., Reijmersdal, S. V., Nillesen, W. M., Huys, E. H. L. P. G., Leeuw, N. D., et al. (2005) · The American Journal of Human Genetics
Genomic variations and chromosomal abnormalitiesGenomics and Rare Diseases
Cited by 605
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Selective Inhibition of CYP17 With Abiraterone Acetate Is Highly Active in the Treatment of Castration-Resistant Prostate Cancer
Attard, G., Reid, A. H. M., A'Hern, R., Parker, C., Oommen, N. B., Folkerd, E., Messiou, C., Molife, L. R., Maier, G., Thompson, E., et al. (2009) · Journal of Clinical Oncology
Prostate Cancer Treatment and ResearchProstate Cancer Diagnosis and Treatment
Cited by 605
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Mechanisms and functions of Hedgehog signalling across the metazoa
Ingham, P. W., Nakano, Y., & Seger, C. (2011) · Nature Reviews Genetics
Hedgehog Signaling Pathway StudiesDevelopmental Biology and Gene Regulation
Cited by 605
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Peroxisomes: A Nexus for Lipid Metabolism and Cellular Signaling
Lodhi, I. J., & Semenkovich, C. F. (2014) · Cell Metabolism
Lipid metabolism and biosynthesisMetabolism and Genetic Disorders
Cited by 605
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Targeting senescent cells enhances adipogenesis and metabolic function in old age
Xu, M., Palmer, A. K., Ding, H., Weivoda, M. M., Pirtskhalava, T., White, T. A., Sepe, A., Johnson, K. O., Stout, M. B., Giorgadze, N., et al. (2015) · eLife
Telomeres, Telomerase, and SenescenceAdipose Tissue and Metabolism
Cited by 604
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Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling
Lo, S., Li, X., Henzl, M. T., Beamer, L. J., & Hannink, M. (2006) · The EMBO Journal
Genomics, phytochemicals, and oxidative stressUbiquitin and proteasome pathways
Cited by 604
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Hypoxia-inducible factor-1 in physiological and pathophysiological angiogenesis: applications and therapies
Zimna, A., & Kurpisz, M. (2015) · BioMed Research International
Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism
Cited by 604
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Influence of Letrozole and Anastrozole on Total Body Aromatization and Plasma Estrogen Levels in Postmenopausal Breast Cancer Patients Evaluated in a Randomized, Cross-Over Study
Geisler, J., Haynes, B., Anker, G., Dowsett, M., & Lønning, P. E. (2002) · Journal of Clinical Oncology
Estrogen and related hormone effectsBreast Cancer Treatment Studies
Cited by 604
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Is the oxidative stress theory of aging dead?
Pérez, V. I., Bokov, A., Remmen, H. V., Mele, J., Ran, Q., Ikeno, Y., & Richardson, A. (2009) · Biochimica et Biophysica Acta (BBA) - General Subjects
Genetics, Aging, and Longevity in Model OrganismsAntioxidant Activity and Oxidative Stress
Cited by 604
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The human gene mutation database
Cooper, D. (1998) · Nucleic Acids Research
Genomics and Rare DiseasesGenetic Associations and Epidemiology
Cited by 604
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WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell mov
Takenawa, T., & Miki, H. (2001) · Journal of Cell Science
Cellular Mechanics and InteractionsProtein Kinase Regulation and GTPase Signaling
Cited by 604
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FoxO transcription factors in the maintenance of cellular homeostasis during aging
Salih, D. A., & Brunet, A. (2008) · Current Opinion in Cell Biology
FOXO transcription factor regulationGenetics, Aging, and Longevity in Model Organisms
Cited by 604
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Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cells.
Squadrito, M. L., Baer, C., Burdet, F., Maderna, C., Gilfillan, G. D., Lyle, R., Ibberson, M., & De Palma, M. (2014) · Cell Reports
Extracellular vesicles in diseaseMicroRNA in disease regulation
Cited by 604
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Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer’s Disease
Begum, A. N., Jones, M. R., Lim, G. P., Morihara, T., Kim, P., Heath, D. D., Rock, C. L., Pruitt, M. A., Yang, F., Hudspeth, B., et al. (2008) · The Journal of Pharmacology and Experimental Therapeutics
Curcumin's Biomedical ApplicationsAlzheimer's disease research and treatments
Cited by 604
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Increased Gut Permeability and Microbiota Change Associate with Mesenteric Fat Inflammation and Metabolic Dysfunction in Diet-Induced Obese Mice
Lam, Y. Y., Ha, C. W. Y., Campbell, C. R., Mitchell, A. J., Dinudom, A., Oscarsson, J., Cook, D. I., Hunt, N. H., Caterson, I. D., Holmes, A. J., et al. (2012) · PLoS ONE
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 604
- Verified
Hematopoietic stem-cell gene therapy for cerebral adrenoleukodystrophy
Eichler, F., Duncan, C., Musolino, P. L., Orchard, P. J., De Oliveira, S., Thrasher, A. J., Armant, M., Dansereau, C., Lund, T. C., Miller, W. P., et al. (2017) · New England Journal of Medicine
Virus-based gene therapy researchLysosomal Storage Disorders Research
Cited by 604
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Exploration of Essential Gene Functions via Titratable Promoter Alleles
Mnaimneh, S., Davierwala, A. P., Haynes, J., Moffat, J., Peng, W.-T., Zhang, W., Yang, X., Pootoolal, J., Chua, G., Lopez, A., et al. (2004) · Cell
Fungal and yeast genetics researchBioinformatics and Genomic Networks
Cited by 604
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Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer
Thomas, G. V., Tran, C., Mellinghoff, I. K., Welsbie, D. S., Chan, E., Fueger, B., Czernin, J., & Sawyers, C. L. (2006) · Nature Medicine
PI3K/AKT/mTOR signaling in cancerCancer, Hypoxia, and Metabolism
Cited by 604
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Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut
Joyce, S. A., MacSharry, J., Casey, P. G., Kinsella, M., Murphy, E. F., Shanahan, F., Hill, C., & Gahan, C. G. M. (2014) · Proceedings of the National Academy of Sciences
Gut microbiota and healthDrug Transport and Resistance Mechanisms
Cited by 604
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Dnmt3a-Dependent Nonpromoter DNA Methylation Facilitates Transcription of Neurogenic Genes
Wu, H., Coskun, V., Tao, J., Xie, W., Ge, W., Yoshikawa, K., Li, E., Zhang, Y., & Sun, Y. E. (2010) · Science
Epigenetics and DNA MethylationNeurogenesis and neuroplasticity mechanisms
Cited by 604
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Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence
Coppé, J.-P., Kauser, K., Campisi, J., & Beauséjour, C. M. (2006) · Journal of Biological Chemistry
Telomeres, Telomerase, and SenescenceAngiogenesis and VEGF in Cancer
Cited by 604
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Rare variant contribution to human disease in 281,104 UK Biobank exomes
Wang, Q., Dhindsa, R. S., Carss, K., Harper, A. R., Nag, A., Tachmazidou, I., Vitsios, D., Deevi, S. V. V., Mackay, A., Muthas, D., et al. (2021) · Nature
Genetic Associations and EpidemiologyGenomics and Rare Diseases
Cited by 604
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