Most cited biochemistry, genetics and molecular biology papers
- Verified
Development of Protacs to Target Cancer-promoting Proteins for Ubiquitination and Degradation
Sakamoto, K. M., Kim, K. B., Verma, R., Ransick, A., Stein, B., Crews, C. M., & Deshaies, R. J. (2003) · Molecular & Cellular Proteomics
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 425
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An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways.
Inoue, T., Heo, W. D., Grimley, J. S., Wandless, T. J., & Meyer, T. (2005) · Nature Methods
Protein Kinase Regulation and GTPase SignalingCellular transport and secretion
Cited by 424
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Genetics and genomics of psychiatric disease
Geschwind, D. H., & Flint, J. (2015) · Science
Genetic Associations and EpidemiologySchizophrenia research and treatment
Cited by 424
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Sequence-Specific Detection of Femtomolar DNA via a Chronocoulometric DNA Sensor (CDS): Effects of Nanoparticle-Mediated Amplification and Nanoscale Control of DNA Assembly at Electrodes
Zhang, J., Song, S., Zhang, L., Wang, L., Wu, H., Pan, D., & Fan, C. (2006) · Journal of the American Chemical Society
Advanced biosensing and bioanalysis techniquesElectrochemical sensors and biosensors
Cited by 424
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Global Analysis of Short RNAs Reveals Widespread Promoter-Proximal Stalling and Arrest of Pol II in Drosophila
Nechaev, S., Fargo, D. C., dos Santos, G., Liu, L., Gao, Y., & Adelman, K. (2010) · Science
Genomics and Chromatin DynamicsRNA Research and Splicing
Cited by 424
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Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials
Meric-Bernstam, F., Brusco, L., Shaw, K., Horombe, C., Kopetz, S., Davies, M. A., Routbort, M., Piha-Paul, S. A., Janku, F., Ueno, N., et al. (2015) · Journal of Clinical Oncology
Cancer Genomics and DiagnosticsLung Cancer Treatments and Mutations
Cited by 424
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Current strategies for the design of PROTAC linkers: a critical review
Troup, R. I., Fallan, C., & Baud, M. G. J. (2020) · Exploration of Targeted Anti-tumor Therapy
Protein Degradation and InhibitorsChemical Synthesis and Analysis
Cited by 424
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Polypeptide Flux through Bacterial Hsp70
Teter, S. A., Houry, W. A., Ang, D., Tradler, T., Rockabrand, D., Fischer, G., Blum, P., Georgopoulos, C., & Hartl, F. U. (1999) · Cell
Heat shock proteins researchBacterial Genetics and Biotechnology
Cited by 424
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Dual Role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation
Wei, Y., Sinha, S. C., & Levine, B. (2008) · Autophagy
Cell death mechanisms and regulationAutophagy in Disease and Therapy
Cited by 424
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The fragment assembly string graph
Myers, E. W. (2005) · Bioinformatics
Genomics and Phylogenetic StudiesAlgorithms and Data Compression
Cited by 424
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Signaling in Muscle Contraction
Kuo, I. Y., & Ehrlich, B. E. (2015) · Cold Spring Harbor Perspectives in Biology
Muscle Physiology and DisordersIon channel regulation and function
Cited by 424
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Inhibition of Experimental Liver Cirrhosis in Mice by Telomerase Gene Delivery
Rudolph, K. L., Chang, S., Millard, M., Schreiber-Agus, N., & DePinho, R. A. (2000) · Science
Telomeres, Telomerase, and SenescenceLiver physiology and pathology
Cited by 424
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Meta-analyses of studies of the human microbiota
Lozupone, C. A., Stombaugh, J., Gonzalez, A., Ackermann, G., Wendel, D., Vázquez-Baeza, Y., Jansson, J. K., Gordon, J. I., & Knight, R. (2013) · Genome Research
Gut microbiota and healthMicrobial Community Ecology and Physiology
Cited by 424
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The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism
Clower, C. V., Chatterjee, D., Wang, Z., Cantley, L. C., Vander Heiden, M. G., & Krainer, A. R. (2010) · Proceedings of the National Academy of Sciences
RNA Research and SplicingCancer, Hypoxia, and Metabolism
Cited by 424
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The Incoherent Feedforward Loop Can Provide Fold-Change Detection in Gene Regulation
Goentoro, L., Shoval, O., Kirschner, M. W., & Alon, U. (2009) · Molecular Cell
Gene Regulatory Network AnalysisBacterial Genetics and Biotechnology
Cited by 424
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Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells
Liu, Y.-C., Yen, H.-Y., Chen, C.-Y., Chen, C.-H., Cheng, P.-F., Juan, Y.-H., Chen, C.-H., Khoo, K.-H., Yu, C.-J., Yang, P.-C., et al. (2011) · Proceedings of the National Academy of Sciences
Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis
Cited by 424
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Tumor Endothelial Cells
Dudley, A. C. (2012) · Cold Spring Harbor Perspectives in Medicine
Angiogenesis and VEGF in CancerBarrier Structure and Function Studies
Cited by 424
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Functional interaction between autophagy and ciliogenesis
Pampliega, O., Orhon, I., Patel, B., Sridhar, S., Díaz-Carretero, A., Beau, I., Codogno, P., Satir, B. H., Satir, P., & Cuervo, A. M. (2013) · Nature
Genetic and Kidney Cyst DiseasesAutophagy in Disease and Therapy
Cited by 424
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Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase
Verba, K. A., Wang, R. Y.-R., Arakawa, A., Liu, Y., Shirouzu, M., Yokoyama, S., & Agard, D. A. (2016) · Science
Heat shock proteins researchProtein Structure and Dynamics
Cited by 424
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Updates to the integrated protein-protein interaction benchmarks: docking benchmark version 5 and affinity benchmark version 2
Vreven, T., Moal, I. H., Vangone, A., Pierce, B. G., Kastritis, P. L., Torchala, M., Chaleil, R., Jiménez-García, B., Bates, P. A., Fernandez-Recio, J., et al. (2015) · Journal of Molecular Biology
Protein Structure and DynamicsComputational Drug Discovery Methods
Cited by 424
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Paircoil2: improved prediction of coiled coils from sequence.
McDonnell, A. V., Jiang, T., Keating, A. E., & Berger, B. (2006) · Bioinformatics
Protein Structure and DynamicsMachine Learning in Bioinformatics
Cited by 424
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Melancholic microbes: a link between gut microbiota and depression
Dinan, T. G., & Cryan, J. F. (2013) · Neurogastroenterology & Motility
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 424
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The Sequence Read Archive: a decade more of explosive growth
Katz, K., Shutov, O., Lapoint, R., Kimelman, M., Brister, J. R., & O’Sullivan, C. (2022) · Nucleic Acids Research
Genomics and Phylogenetic StudiesResearch Data Management Practices
Cited by 424
- Verified
Autophagy and the cell biology of age-related disease
Leidal, A. M., Levine, B., & Debnath, J. (2018) · Nature Cell Biology
Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms
Cited by 424
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