Most cited biochemistry, genetics and molecular biology papers
- Verified
Microdeletion/duplication at 15q13.2q13.3 among individuals with features of autism and other neuropsychiatric disorders.
Miller, D. T., Shen, Y., Weiss, L. A., Korn, J., Anselm, I., Bridgemohan, C., Cox, G. F., Dickinson, H., Gentile, J., Harris, D. J., et al. (2009) · Journal of Medical Genetics
Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders
Cited by 427
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Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy
Wander, S. A., Hennessy, B. T., & Slingerland, J. M. (2011) · Journal of Clinical Investigation
PI3K/AKT/mTOR signaling in cancerAdvanced Breast Cancer Therapies
Cited by 427
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Cancer in xeroderma pigmentosum and related disorders of DNA repair
Cleaver, J. E. (2005) · Nature Reviews Cancer
DNA Repair MechanismsGenetic and rare skin diseases.
Cited by 427
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Drugging the undruggables: exploring the ubiquitin system for drug development
Huang, X., & Dixit, V. M. (2016) · Cell Research
Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors
Cited by 427
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Hepatocyte IKKβ/NF-κB Inhibits Tumor Promotion and Progression by Preventing Oxidative Stress-Driven STAT3 Activation
He, G., Yu, G.-Y., Temkin, V., Ogata, H., Kuntzen, C., Sakurai, T., Sieghart, W., Peck-Radosavljevic, M., Leffert, H. L., & Karin, M. (2010) · Cancer Cell
NF-κB Signaling PathwaysCytokine Signaling Pathways and Interactions
Cited by 427
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Plasma membrane deformation by circular arrays of ESCRT-III protein filaments
Hanson, P. I., Roth, R., Lin, Y., & Heuser, J. E. (2008) · The Journal of Cell Biology
Cellular transport and secretionLipid Membrane Structure and Behavior
Cited by 427
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Role of nitric oxide in angiogenesis and tumor progression in head and neck cancer
Gallo, O., Fini-Storchi, I., Vergari, W. A., Masini, E., Morbidelli, L., Ziche, M., & Franchi, A. (1998) · JNCI Journal of the National Cancer Institute
Angiogenesis and VEGF in CancerNitric Oxide and Endothelin Effects
Cited by 427
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Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood
Qi, T., Wu, Y., Zeng, J., Zhang, F., Xue, A., Jiang, L., Zhu, Z., Kemper, K., Yengo, L., Zheng, Z., et al. (2018) · Nature Communications
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 427
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Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction
Chen, S., Henderson, A., Petriello, M. C., Romano, K. A., Gearing, M., Miao, J., Schell, M., Sandoval-Espinola, W. J., Tao, J., Sha, B., et al. (2019) · Cell Metabolism
Endoplasmic Reticulum Stress and DiseaseGut microbiota and health
Cited by 427
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DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis
Dasika, G. K., Lin, S.-C. J., Zhao, S., Sung, P., Tomkinson, A., & Lee, E. Y.-H. P. (1999) · Oncogene
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 427
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Large-Scale Cellular-Resolution Gene Profiling in Human Neocortex Reveals Species-Specific Molecular Signatures
Zeng, H., Shen, E. H., Hohmann, J. G., Oh, S. W., Bernard, A., Royall, J. J., Glattfelder, K. J., Sunkin, S. M., Morris, J. A., Guillozet-Bongaarts, A. L., et al. (2012) · Cell
Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research
Cited by 426
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RNA Binding to CBP Stimulates Histone Acetylation and Transcription
Bose, D. A., Donahue, G., Reinberg, D., Shiekhattar, R., Bonasio, R., & Berger, S. L. (2017) · Cell
Genomics and Chromatin DynamicsCancer-related molecular mechanisms research
Cited by 426
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AMPK, the metabolic syndrome and cancer
Luo, Z., Saha, A. K., Xiang, X., & Ruderman, N. B. (2005) · Trends in Pharmacological Sciences
Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer
Cited by 426
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m 6 A in mRNA: An Ancient Mechanism for Fine-Tuning Gene Expression
Roignant, J.-Y., & Soller, M. (2017) · Trends in Genetics
RNA modifications and cancerRNA regulation and disease
Cited by 426
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Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ
Wei, W., Dutchak, P. A., Wang, X., Ding, X., Wang, X., Bookout, A. L., Goetz, R., Mohammadi, M., Gerard, R. D., Dechow, P. C., et al. (2012) · Proceedings of the National Academy of Sciences
Fibroblast Growth Factor ResearchBone Metabolism and Diseases
Cited by 426
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Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates
Hoffman, N. J., Parker, B. L., Chaudhuri, R., Fisher-Wellman, K. H., Kleinert, M., Humphrey, S. J., Yang, P., Holliday, M., Trefely, S., Fazakerley, D. J., et al. (2015) · Cell Metabolism
Metabolism, Diabetes, and CancerMuscle metabolism and nutrition
Cited by 426
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Adjustment of systematic microarray data biases
Benito, M., Parker, J., Du, Q., Wu, J., Xiang, D., Perou, C. M., & Marron, J. S. (2004) · Bioinformatics
Gene expression and cancer classificationBioinformatics and Genomic Networks
Cited by 426
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Nitrate and periplasmic nitrate reductases
Sparacino-Watkins, C., Stolz, J. F., & Basu, P. (2014) · Chem. Soc. Rev.
Metalloenzymes and iron-sulfur proteinsWastewater Treatment and Nitrogen Removal
Cited by 426
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Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization
Fan, D., Coughlin, L. A., Neubauer, M. M., Kim, J., Kim, M. S., Zhan, X., Simms-Waldrip, T. R., Xie, Y., Hooper, L. V., & Koh, A. Y. (2015) · Nature Medicine
Gut microbiota and healthAntifungal resistance and susceptibility
Cited by 426
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Cell wall sorting signals in surface proteins of gram‐positive bacteria.
Schneewind, O., Mihaylova‐Petkov, D., & Model, P. (1993) · The EMBO Journal
Biochemical and Structural CharacterizationBacterial Genetics and Biotechnology
Cited by 426
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DNA methylation of BDNF as a biomarker of early-life adversity
Kundakovic, M., Gudsnuk, K., Herbstman, J. B., Tang, D., Perera, F. P., & Champagne, F. A. (2015) · Proceedings of the National Academy of Sciences
Epigenetics and DNA MethylationChild Abuse and Trauma
Cited by 426
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The Neurotropic Properties of AAV-PHP.B Are Limited to C57BL/6J Mice
Hordeaux, J., Wang, Q., Katz, N., Buza, E. L., Bell, P., & Wilson, J. M. (2018) · Molecular Therapy
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 426
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ECOD: an evolutionary classification of protein domains
Cheng, H., Schaeffer, R. D., Liao, Y., Kinch, L. N., Pei, J., Shi, S., Kim, B.-H., & Grishin, N. V. (2014) · PLoS Computational Biology
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 426
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Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy
Gao, X., Ran, N., Dong, X., Zuo, B., Yang, R., Zhou, Q., Moulton, H. M., Seow, Y., & Yin, H. (2018) · Science Translational Medicine
Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery
Cited by 426
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