Most cited biochemistry, genetics and molecular biology papers
- Verified
The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate
Jurica, M. S., Mesecar, A., Heath, P. J., Shi, W., Nowak, T., & Stoddard, B. L. (1998) · Structure
Enzyme Structure and FunctionProtein Structure and Dynamics
Cited by 426
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Extreme Dysbiosis of the Microbiome in Critical Illness
McDonald, D., Ackermann, G., Khailova, L., Baird, C., Heyland, D., Kozar, R., Lemieux, M., Derenski, K., King, J., Vis-Kampen, C., et al. (2016) · mSphere
Gut microbiota and healthSepsis Diagnosis and Treatment
Cited by 426
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The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls
Kummen, M., Holm, K., Anmarkrud, J. A., Nygård, S., Vesterhus, M., Høivik, M. L., Trøseid, M., Marschall, H.-U., Schrumpf, E., Moum, B., et al. (2017) · Gut
Gut microbiota and healthLiver Diseases and Immunity
Cited by 426
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Marine natural products and their potential applications as anti-infective agents
Donia, M., & Hamann, M. T. (2003) · The Lancet Infectious Diseases
Marine Sponges and Natural ProductsMicrobial Natural Products and Biosynthesis
Cited by 425
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Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapies
Fauvart, M., De Groote, V. N., & Michiels, J. (2011) · Journal of Medical Microbiology
Bacterial Genetics and BiotechnologyBacterial biofilms and quorum sensing
Cited by 425
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lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling
Lu, Y., Zhao, X., Liu, Q., Li, C., Graves-Deal, R., Cao, Z., Singh, B., Franklin, J. L., Wang, J., Hu, H., et al. (2017) · Nature Medicine
MicroRNA in disease regulationCancer-related molecular mechanisms research
Cited by 425
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Cell heterogeneity upon myogenic differentiation: down-regulation of MyoD and Myf-5 generates ‘reserve cells
Yoshida, N., Yoshida, S., Koishi, K., Masuda, K., & Nabeshima, Y.-I. (1998) · Journal of Cell Science
Muscle Physiology and DisordersDevelopmental Biology and Gene Regulation
Cited by 425
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Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming
Betz, A., Thakur, P., Junge, H. J., Ashery, U., Rhee, J.-S., Scheuss, V., Rosenmund, C., Rettig, J., & Brose, N. (2001) · Neuron
Cellular transport and secretionNeuroscience and Neuropharmacology Research
Cited by 425
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Spatially resolved multiomics of human cardiac niches
Kanemaru, K., Cranley, J., Muraro, D., Miranda, A. M. A., Ho, S. Y., Wilbrey-Clark, A., Patrick Pett, J., Polanski, K., Richardson, L., Litvinukova, M., et al. (2023) · Nature
Single-cell and spatial transcriptomicsCardiac electrophysiology and arrhythmias
Cited by 425
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Pulsating Fluid Flow Increases Nitric Oxide (NO) Synthesis by Osteocytes but Not Periosteal Fibroblasts - Correlation with Prostaglandin Upregulation
Kleinnulend, J., Semeins, C. M., Ajubi, N. E., Nijweide, P. J., & Burger, E. H. (1995) · Biochemical and Biophysical Research Communications
Bone Metabolism and DiseasesCellular Mechanics and Interactions
Cited by 425
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Two-photon microscopy in brain tissue: parameters influencing the imaging depth
Oheim, M., Beaurepaire, E., Chaigneau, E., Mertz, J., & Charpak, S. (2001) · Journal of Neuroscience Methods
Advanced Fluorescence Microscopy TechniquesOptical Imaging and Spectroscopy Techniques
Cited by 425
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NLRP3 inflammasomes link inflammation and metabolic disease
De Nardo, D., & Latz, E. (2011) · Trends in Immunology
Inflammasome and immune disordersAdipokines, Inflammation, and Metabolic Diseases
Cited by 425
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Modulation of the Intestinal Microbiota Alters Colitis-Associated Colorectal Cancer Susceptibility
Uronis, J. M., Mühlbauer, M., Herfarth, H. H., Rubinas, T. C., Jones, G. S., & Jobin, C. (2009) · PLoS ONE
Gut microbiota and healthInflammatory Bowel Disease
Cited by 425
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New Component of the Vacuolar Class C-Vps Complex Couples Nucleotide Exchange on the Ypt7 Gtpase to Snare-Dependent Docking and Fusion
Wurmser, A. E., Sato, T. K., & Emr, S. D. (2000) · The Journal of Cell Biology
Cellular transport and secretionFungal and yeast genetics research
Cited by 425
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A pessimistic estimate of the time required for an eye to evolve
Nilsson, D., & Pelger, S. (1994) · Proceedings of the Royal Society of London. Series B: Biological Sciences
Evolution and Genetic DynamicsEvolution and Paleontology Studies
Cited by 425
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Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release
Betz, A., Ashery, U., Rickmann, M., Augustin, I., Neher, E., Südhof, T. C., Rettig, J., & Brose, N. (1998) · Neuron
Cellular transport and secretionNeuroscience and Neuropharmacology Research
Cited by 425
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Estimates of penetrance for recurrent pathogenic copy-number variations
Rosenfeld, J. A., Coe, B. P., Eichler, E. E., Cuckle, H., & Shaffer, L. G. (2013) · Genetics in Medicine
Genomic variations and chromosomal abnormalitiesPrenatal Screening and Diagnostics
Cited by 425
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Age‐related changes in the lipid compositions of rat and human tissues
Kalén, A., Appelkvist, E., & Dallner, G. (1989) · Lipids
Cholesterol and Lipid MetabolismLipid metabolism and biosynthesis
Cited by 425
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Peroxisome proliterator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis
Fruchart, J.-C., Duriez, P., & Staels, B. (1999) · Current Opinion in Lipidology
Peroxisome Proliferator-Activated ReceptorsCholesterol and Lipid Metabolism
Cited by 425
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A Dynein Light Chain Is Essential for the Retrograde Particle Movement of Intraflagellar Transport (IFT)
Pazour, G. J., Wilkerson, C. G., & Witman, G. B. (1998) · The Journal of Cell Biology
Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances
Cited by 425
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The discovery of placenta growth factor and its biological activity
De Falco, S. (2012) · Experimental and Molecular Medicine
Angiogenesis and VEGF in CancerFibroblast Growth Factor Research
Cited by 425
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Alterations in composition and diversity of the intestinal microbiota in patients with diarrhea‐predominant irritable bowel syndrome
Carroll, I. M., Ringel‐Kulka, T., Siddle, J. P., & Ringel, Y. (2012) · Neurogastroenterology & Motility
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 425
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An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance
He, M., Chiang, H.-H., Luo, H., Zheng, Z., Qiao, Q., Wang, L., Tan, M., Ohkubo, R., Mu, W.-C., Zhao, S., et al. (2020) · Cell Metabolism
Inflammasome and immune disordersSirtuins and Resveratrol in Medicine
Cited by 425
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Tumor exosomes inhibit differentiation of bone marrow dendritic cells
Yu, S., Liu, C., Su, K., Wang, J., Liu, Y., Zhang, L., Li, C., Cong, Y., Kimberly, R., Grizzle, W. E., et al. (2007) · The Journal of Immunology
Extracellular vesicles in diseaseImmunotherapy and Immune Responses
Cited by 425
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