Most cited biochemistry, genetics and molecular biology papers
- Verified
YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers
Stein, C., Bardet, A. F., Roma, G., Bergling, S., Clay, I., Ruchti, A., Agarinis, C., Schmelzle, T., Bouwmeester, T., Schübeler, D., et al. (2015) · PLOS Genetics
Hippo pathway signaling and YAP/TAZGenomics and Chromatin Dynamics
Cited by 414
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Robustness–epistasis link shapes the fitness landscape of a randomly drifting protein
Bershtein, S., Segal, M., Bekerman, R., Tokuriki, N., & Tawfik, D. S. (2006) · Nature
Evolution and Genetic DynamicsRNA and protein synthesis mechanisms
Cited by 414
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TINF2, a Component of the Shelterin Telomere Protection Complex, Is Mutated in Dyskeratosis Congenita
Savage, S. A., Giri, N., Baerlocher, G. M., Orr, N., Lansdorp, P. M., & Alter, B. P. (2008) · The American Journal of Human Genetics
Telomeres, Telomerase, and SenescenceBlood disorders and treatments
Cited by 414
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Evolution of the chordate body plan: New insights from phylogenetic analyses of deuterostome phyla
Cameron, C. B., Garey, J. R., & Swalla, B. J. (2000) · Proceedings of the National Academy of Sciences
Developmental Biology and Gene RegulationMarine Invertebrate Physiology and Ecology
Cited by 414
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Spatiotemporal transcriptomic divergence across human and macaque brain development
Zhu, Y., Sousa, A. M. M., Gao, T., Skarica, M., Li, M., Santpere, G., Esteller-Cucala, P., Juan, D., Ferrández-Peral, L., Gulden, F. O., et al. (2018) · Science
Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation
Cited by 414
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Necroptosis in health and diseases
Zhou, W., & Yuan, J. (2014) · Seminars in Cell & Developmental Biology
Cell death mechanisms and regulationNF-κB Signaling Pathways
Cited by 414
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The effect of short-chain fatty acids on human monocyte-derived dendritic cells
Nastasi, C., Candela, M., Bonefeld, C. M., Geisler, C., Hansen, M., Krejsgaard, T., Biagi, E., Andersen, M. H., Brigidi, P., Ødum, N., et al. (2015) · Scientific Reports
Gut microbiota and healthImmune Response and Inflammation
Cited by 414
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Unique roles of tryptophanyl-tRNA synthetase in immune control and its therapeutic implications
Jin, M. (2019) · Experimental & Molecular Medicine
RNA and protein synthesis mechanismsImmune Response and Inflammation
Cited by 413
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Putting the stress on senescence
Serrano, M., & Blasco, M. A. (2001) · Current Opinion in Cell Biology
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 413
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Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma
Guillaumond, F., Leca, J., Olivares, O., Lavaut, M.-N., Vidal, N., Berthezène, P., Dusetti, N. J., Loncle, C., Calvo, E., Turrini, O., et al. (2013) · Proceedings of the National Academy of Sciences
Cancer, Hypoxia, and MetabolismPancreatic and Hepatic Oncology Research
Cited by 413
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Source of chronic inflammation in aging
Sanada, F., Taniyama, Y., Muratsu, J., Otsu, R., Shimizu, H., Rakugi, H., & Morishita, R. (2018) · Frontiers in Cardiovascular Medicine
Genetics, Aging, and Longevity in Model OrganismsInflammasome and immune disorders
Cited by 413
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Segmental distribution of bithorax complex proteins during Drosophila development
Beachy, P. A., Helfand, S. L., & Hogness, D. S. (1985) · Nature
Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation
Cited by 413
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The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients
Marchetti, P., Bugliani, M., Lupi, R., Marselli, L., Masini, M., Boggi, U., Filipponi, F., Weir, G. C., Eizirik, D. L., & Cnop, M. (2007) · Diabetologia
Endoplasmic Reticulum Stress and DiseasePancreatic function and diabetes
Cited by 413
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The structure and function of small nucleolar ribonucleoproteins
Reichow, S. L., Hamma, T., Ferre-D'Amare, A. R., & Varani, G. (2007) · Nucleic Acids Research
RNA modifications and cancerRNA and protein synthesis mechanisms
Cited by 413
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Irinotecan: mechanisms of tumor resistance and novel strategies for modulating its activity.
Xu, Y., & Villalona-Calero, M. A. (2002) · Annals of Oncology
Cancer therapeutics and mechanismsDrug Transport and Resistance Mechanisms
Cited by 413
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Mechanistic insight into osteoclast differentiation in osteoimmunology
Takayanagi, H. (2005) · Journal of Molecular Medicine
Bone Metabolism and DiseasesRheumatoid Arthritis Research and Therapies
Cited by 413
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An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function
Scroggins, B. T., Robzyk, K., Wang, D., Marcu, M. G., Tsutsumi, S., Beebe, K., Cotter, R. J., Felts, S., Toft, D., Karnitz, L., et al. (2007) · Molecular Cell
Heat shock proteins researchUbiquitin and proteasome pathways
Cited by 413
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MAPKAP kinases — MKs — two's company, three's a crowd
Gaestel, M. (2006) · Nature Reviews Molecular Cell Biology
Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways
Cited by 413
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The International Mouse Phenotyping Consortium: comprehensive knockout phenotyping underpinning the study of human disease
Groza, T., Gomez, F. L., Mashhadi, H. H., Muñoz-Fuentes, V., Gunes, O., Wilson, R., Cacheiro, P., Frost, A., Keskivali-Bond, P., Vardal, B., et al. (2023) · Nucleic Acids Research
Genomics and Rare DiseasesBioinformatics and Genomic Networks
Cited by 413
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Osteoblast and osteocyte: Games without frontiers
Capulli, M., Paone, R., & Rucci, N. (2014) · Archives of Biochemistry and Biophysics
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 413
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Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps
Polygenic Risk Score Task Force of the International Common Disease Alliance, Adeyemo, A., Balaconis, M. K., Darnes, D. R., Fatumo, S., Granados Moreno, P., Hodonsky, C. J., Inouye, M., Kanai, M., Kato, K., et al. (2021) · Nature Medicine
Genetic Associations and EpidemiologyRace, Genetics, and Society
Cited by 413
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Protein Degradation by In-Cell Self-Assembly of Proteolysis Targeting Chimeras
Lebraud, H., Wright, D. J., Johnson, C. N., & Heightman, T. D. (2016) · ACS Central Science
Protein Degradation and InhibitorsClick Chemistry and Applications
Cited by 413
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Activation of rhodopsin: new insights from structural and biochemical studies
Okada, T., Ernst, O. P., Palczewski, K., & Hofmann, K. P. (2001) · Trends in Biochemical Sciences
Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research
Cited by 413
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Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine
Minor, E. A., Court, B. L., Young, J. I., & Wang, G. (2013) · Journal of Biological Chemistry
Epigenetics and DNA MethylationVitamin C and Antioxidants Research
Cited by 413
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