Most cited biochemistry, genetics and molecular biology papers
- Verified
A role for the gut microbiota in IBS
Collins, S. M. (2014) · Nature Reviews Gastroenterology & Hepatology
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 351
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Programmable RNA editing with compact CRISPR–Cas13 systems from uncultivated microbes
Xu, C., Zhou, Y., Xiao, Q., He, B., Geng, G., Wang, Z., Cao, B., Dong, X., Bai, W., Wang, Y., et al. (2021) · Nature Methods
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 351
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De novo design of a fluorescence-activating β-barrel
Dou, J., Vorobieva, A. A., Sheffler, W., Doyle, L. A., Park, H., Bick, M. J., Mao, B., Foight, G. W., Lee, M. Y., Gagnon, L. A., et al. (2018) · Nature
Protein Structure and DynamicsBiochemical and Structural Characterization
Cited by 351
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Genome graphs and the evolution of genome inference
Paten, B., Novak, A. M., Eizenga, J. M., & Garrison, E. (2017) · Genome Research
Genomics and Phylogenetic StudiesAlgorithms and Data Compression
Cited by 351
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Autophagy and the ubiquitin-proteasome system: Collaborators in neuroprotection
Nedelsky, N. B., Todd, P. K., & Taylor, J. P. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Autophagy in Disease and TherapyUbiquitin and proteasome pathways
Cited by 351
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Carcinogenicity of deoxycholate, a secondary bile acid
Bernstein, C., Holubec, H., Bhattacharyya, A. K., Nguyen, H., Payne, C. M., Zaitlin, B., & Bernstein, H. (2011) · Archives of Toxicology
Carcinogens and Genotoxicity AssessmentAntioxidant Activity and Oxidative Stress
Cited by 351
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Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins
Brooks, C., Wei, Q., Feng, L., Dong, G., Tao, Y., Mei, L., Xie, Z.-J., & Dong, Z. (2007) · Proceedings of the National Academy of Sciences
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 351
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Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis
Sergin, I., Evans, T. D., Zhang, X., Bhattacharya, S., Stokes, C. J., Song, E., Ali, S., Dehestani, B., Holloway, K. B., Micevych, P. S., et al. (2017) · Nature Communications
Autophagy in Disease and TherapyAtherosclerosis and Cardiovascular Diseases
Cited by 351
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The Effect of Carbon and Nitrogen Sources on the Level of Metabolic Intermediates in Escherichia coli
Lowry, O. H., Carter, J., Ward, J. B., & Glaser, L. (1971) · Journal of Biological Chemistry
Bacterial Genetics and BiotechnologyMicrobial Metabolic Engineering and Bioproduction
Cited by 350
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Type 1 diabetes associated autoimmunity: natural history, genetic associations and screening
Barker, J. M. (2006) · The Journal of Clinical Endocrinology & Metabolism
Diabetes and associated disordersCeliac Disease Research and Management
Cited by 350
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Rac1 GTPase: A “Rac” of All Trades
Bosco, E. E., Mulloy, J. C., & Zheng, Y. (2009) · Cellular and Molecular Life Sciences
Protein Kinase Regulation and GTPase SignalingCellular transport and secretion
Cited by 350
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The protein phosphatase calcineurin is essential for NaCl tolerance of Saccharomyces cerevisiae.
Mendoza, I., Rubio, F., Rodriguez-Navarro, A., & Pardo, J. M. (1994) · Journal of Biological Chemistry
Fungal and yeast genetics researchSignaling Pathways in Disease
Cited by 350
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Genetic Evidence for Recent Population Mixture in India
Moorjani, P., Thangaraj, K., Patterson, N., Lipson, M., Loh, P.-R., Govindaraj, P., Berger, B., Reich, D., & Singh, L. (2013) · The American Journal of Human Genetics
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 350
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Mice lacking specific nicotinic acetylcholine receptor subunits exhibit dramatically altered spontaneous activity patterns and reveal a limited role for retinal waves in forming ON and OFF circuits in the inner retina
Bansal, A., Singer, J. H., Hwang, B. J., Xu, W., Beaudet, A., & Feller, M. B. (2000) · The Journal of Neuroscience
Nicotinic Acetylcholine Receptors StudyRetinal Development and Disorders
Cited by 350
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Virus-induced senescence is a driver and therapeutic target in COVID-19
Lee, S., Yu, Y., Trimpert, J., Benthani, F., Mairhofer, M., Richter-Pechanska, P., Wyler, E., Belenki, D., Kaltenbrunner, S., Pammer, M., et al. (2021) · Nature
Telomeres, Telomerase, and SenescenceCOVID-19 Clinical Research Studies
Cited by 350
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The Hypoxia-Associated Factor Switches Cells from HIF-1α- to HIF-2α-Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion
Koh, M. Y., Lemos, R., Liu, X., & Powis, G. (2011) · Cancer Research
Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer
Cited by 350
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Antibody–PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4
Maneiro, M., Forte, N., Shchepinova, M. M., Kounde, C. S., Chudasama, V., Baker, J. R., & Tate, E. W. (2020) · ACS Chemical Biology
Protein Degradation and InhibitorsChemical Synthesis and Analysis
Cited by 350
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Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning
D'Orazio, J. A., Nobuhisa, T., Cui, R., Arya, M., Spry, M., Wakamatsu, K., Igras, V., Kunisada, T., Granter, S. R., Nishimura, E. K., et al. (2006) · Nature
melanin and skin pigmentationSkin Protection and Aging
Cited by 350
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Proteomic method identifies proteins nitrated in vivo during inflammatory challenge
Aulak, K. S., Miyagi, M., Yan, L., West, K. A., Massillon, D., Crabb, J. W., & Stuehr, D. J. (2001) · Proceedings of the National Academy of Sciences
Redox biology and oxidative stressNitric Oxide and Endothelin Effects
Cited by 350
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Studies of endogenous retroviruses reveal a continuing evolutionary saga
Stoye, J. P. (2012) · Nature Reviews Microbiology
Chromosomal and Genetic VariationsEvolution and Genetic Dynamics
Cited by 350
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Genetics of type 2 diabetes
Ali, O. (2013) · World Journal of Diabetes
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 350
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Inhibition of Tumor Cell Growth, Invasion, and Metastasis by EXEL-2880 (XL880, GSK1363089), a Novel Inhibitor of HGF and VEGF Receptor Tyrosine Kinases
Qian, F., Engst, S., Yamaguchi, K., Yu, P., Won, K.-A., Mock, L., Lou, T., Tan, J., Li, C., Tam, D., et al. (2009) · Cancer Research
Angiogenesis and VEGF in CancerCancer Mechanisms and Therapy
Cited by 350
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Calcineurin A of Candida albicans: involvement in antifungal tolerance, cell morphogenesis and virulence
Sanglard, D., Ischer, F., Marchetti, O., Entenza, J., & Bille, J. (2003) · Molecular Microbiology
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 350
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Tracking footprints of artificial selection in the dog genome
Akey, J. M., Ruhe, A. L., Akey, D. T., Wong, A. K., Connelly, C. F., Madeoy, J., Nicholas, T. J., & Neff, M. W. (2010) · Proceedings of the National Academy of Sciences
Genetic and phenotypic traits in livestockHuman-Animal Interaction Studies
Cited by 350
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