Cited by 343Cardiac Health and Mental HealthTelemedicine and Telehealth ImplementationCancer survivorship and care

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Telephone-Delivered Collaborative Care for Treating Post-CABG Depression: A Randomized Controlled Trial

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Rollman, Bruce L., Belnap, Bea Herbeck, LeMenager, Michelle S., Mazumdar, Sati, Houck, Patricia R., Counihan, Peter J., Kapoor, Wishwa N., Schulberg, Herbert C., Reynolds, Charles F.·2009·JAMA

DOI 10.1001/jama.2009.1670PMC PMC3010227

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Abstract

CONTEXT: Depressive symptoms commonly follow coronary artery bypass graft (CABG) surgery and are associated with less positive clinical outcomes. OBJECTIVE: To test the effectiveness of telephone-delivered collaborative care for post-CABG depression vs usual physician care. DESIGN, SETTING, AND PARTICIPANTS: Single-blind effectiveness trial at 7 university-based and community hospitals in or near Pittsburgh, Pennsylvania. Participants were 302 post-CABG patients with depression (150, intervention; 152, usual care) and a comparison group of 151 randomly sampled post-CABG patients without depression recruited between March 2004 and September 2007 and observed as outpatients until June 2008. INTERVENTION: Eight months of telephone-delivered collaborative care provided by nurses working with patients' primary care physicians and supervised by a psychiatrist and primary care physician from this study. MAIN OUTCOME MEASURES: Mental health-related quality of life (HRQL) measured by the Short Form-36 Mental Component Summary (SF-36 MCS) at 8-month follow-up; secondary outcome measures included assessment of mood symptoms (Hamilton Rating Scale for Depression [HRS-D]), physical HRQL (SF-36 PCS), and functional status (Duke Activity Status Index [DASI]); and hospital readmissions. RESULTS: The intervention patients reported greater improvements in mental HRQL (all P < or = .02) (SF-36 MCS: Delta, 3.2 points; 95% confidence interval [CI], 0.5-6.0), physical functioning (DASI: Delta, 4.6 points; 95% CI, 1.9-7.3), and mood symptoms (HRS-D: Delta, 3.1 points; 95% CI, 1.3-4.9); and were more likely to report a 50% or greater decline in HRS-D score from baseline (50.0% vs 29.6%; number needed to treat, 4.9 [95% CI, 3.2-10.4]) than usual care patients (P < .001). Men with depression were particularly likely to benefit from the intervention (SF-36 MCS: Delta, 5.7 points; 95% CI, 2.2-9.2; P = .001). However, the mean HRQL and physical functioning of intervention patients did not reach that of the nondepressed comparison group. CONCLUSION: Compared with usual care, telephone-delivered collaborative care for treatment of post-CABG depression resulted in improved HRQL, physical functioning, and mood symptoms at 8-month follow-up. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00091962.

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Authors: Rollman, B. L., Belnap, B. H., LeMenager, M. S., Mazumdar, S., Houck, P. R., Counihan, P. J., Kapoor, W. N., Schulberg, H. C., & Reynolds, C. F.
Affiliations: University of Pittsburgh (US)
ORCID: Rollman, Bruce L.
Belnap, Bea Herbeck
Reynolds, Charles F.
Venue: JAMA
Publisher: American Medical Association (AMA)
Published: 2009-11-18
Volume: 302
Issue: 19
Pages: 2095
ISSN: 0002-9955 (ISSN-L)
0098-7484
DOI: 10.1001/jama.2009.1670
PMC: PMC3010227
OpenAlex: W2018228451
Cited by: 343
References: 70
Citations by year: 2026: 6 · 2025: 10 · 2024: 7 · 2023: 10 · 2022: 13 · 2021: 13 · 2020: 10 · 2019: 15 · 2018: 17 · 2017: 19 · 2016: 28 · 2015: 28 · 2014: 25 · 2013: 34 · 2012: 34
FWCI: 22.86
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: JAMA (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health
National Heart, Lung, and Blood Institute (R01HL070000, R01 HL70000)
National Institute of Mental Health (P30-MH 71944, P30MH071944)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
Health Sciences › Medicine › Oncology › Cancer survivorship and care
Keywords: depression treatment, mental health-related quality of life, physical function, mood symptoms, hospital readmission, cardiac surgery outcomes, nurse-led care, primary care
MeSH terms: Aged, Antidepressive Agents, Coronary Artery Bypass, Continuity of Patient Care, Depression, Depressive Disorder, Female, Health Status Indicators, Humans, Male, Middle Aged, Outcome and Process Assessment, Health Care, Patient Care Team, Patient Education as Topic, Telephone, Single-Blind Method, Telemedicine

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