The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index; none of the 52 sources its claims cite is checked for support yet.
Gait speed and survival in older adults.
Open accessAbstract
CONTEXT: Survival estimates help individualize goals of care for geriatric patients, but life tables fail to account for the great variability in survival. Physical performance measures, such as gait speed, might help account for variability, allowing clinicians to make more individualized estimates. OBJECTIVE: To evaluate the relationship between gait speed and survival. DESIGN, SETTING, AND PARTICIPANTS: Pooled analysis of 9 cohort studies (collected between 1986 and 2000), using individual data from 34,485 community-dwelling older adults aged 65 years or older with baseline gait speed data, followed up for 6 to 21 years. Participants were a mean (SD) age of 73.5 (5.9) years; 59.6%, women; and 79.8%, white; and had a mean (SD) gait speed of 0.92 (0.27) m/s. MAIN OUTCOME MEASURES: Survival rates and life expectancy. RESULTS: There were 17,528 deaths; the overall 5-year survival rate was 84.8% (confidence interval [CI], 79.6%-88.8%) and 10-year survival rate was 59.7% (95% CI, 46.5%-70.6%). Gait speed was associated with survival in all studies (pooled hazard ratio per 0.1 m/s, 0.88; 95% CI, 0.87-0.90; P < .001). Survival increased across the full range of gait speeds, with significant increments per 0.1 m/s. At age 75, predicted 10-year survival across the range of gait speeds ranged from 19% to 87% in men and from 35% to 91% in women. Predicted survival based on age, sex, and gait speed was as accurate as predicted based on age, sex, use of mobility aids, and self-reported function or as age, sex, chronic conditions, smoking history, blood pressure, body mass index, and hospitalization. CONCLUSION: In this pooled analysis of individual data from 9 selected cohorts, gait speed was associated with survival in older adults.
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“Stratification by sex-specific median height failed to show systematic differences in survival rates between short and tall participants, so results presented are not stratified by height.”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“In some subsets of slow walkers of Hispanic descent, survival rates were 10% to 20% higher than in other groups (eTable 2).”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“At age 75, predicted 10-year survival across the range of gait speeds ranged from 19% to 87% in men and from 35% to 91% in women.”
§ Gait Speed and Survival in Older Adults > Abstract > Results
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“Stratification by race/ethnicity (non-Hispanic white, black, Hispanic) suggested generally similar survival rates by gait speed among age and sex groups.”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“Gait speed was associated with survival in all studies (pooled hazard ratio per 0.1 m/s, 0.88; 95% CI, 0.87–0.90; P<. 001).”
- Also stated in: § RESULTS · plain
“The overall HR for survival per each 0.1 m/s faster gait speed was 0.88 (95% CI, 0.87–0.90; P<.001) when pooled across all studies using a random-effects meta-analytic statistical approach”
- Also stated in: § Conclusion · plain
“In this pooled analysis of individual data from 9 selected cohorts, gait speed was associated with survival in older adults.”
§ Gait Speed and Survival in Older Adults > Abstract > Results
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“Gait speeds of 1.0 m/s or higher consistently demonstrated survival that was longer than expected by age and sex alone.”
§ Gait Speed and Survival in Older Adults > RESULTS
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“Gait speed added substantially37 to age and sex in 7 of the 9 studies and in the pooled analysis.”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“Gait speed, age, and sex yielded a C statistic (0.734) that was not significantly different from age, sex, mobility aids, and functional status (0.732; (P=.95; Table 3).”
§ Gait Speed and Survival in Older Adults > RESULTS
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“Three studies had sufficiently consistent data on functional status at baseline to allow pooling.”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“Although the sample size of very slow walkers was small, our data suggest that there may be a subpopulation who walk very slowly but survive for long periods.”
§ Gait Speed and Survival in Older Adults > COMMENT
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“Study follow-up time ranged from 6.0 to 21.0 years, with participants followed up for a mean of 12.2 and a median of 13.8 years.”
§ Gait Speed and Survival in Older Adults > RESULTS
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“Of the total, 59.6% were women.”
§ Gait Speed and Survival in Older Adults > RESULTS
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“Predicted years of remaining life for each sex and age increased as gait speed increased, with a gait speed of about 0.8 m/s at the median life expectancy at most ages for both sexes (Figure 2; a PDF of enlarged graphs is available at http://www.jama.com).”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“Similarly, there was a wide range of gait speeds, from less than 0.4 m/s (n=1247) to more than 1.4 m/s (n=1491).”
§ Gait Speed and Survival in Older Adults > RESULTS
Strength:plain· not yet calibratedn = 1,491Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
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“In this older adult population, the relationship of gait speed with remaining years of life was consistent across age groups, but the absolute number of expected remaining years of life was larger at younger ages.”
§ Gait Speed and Survival in Older Adults > RESULTS
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“For 70-year-old men, life expectancy ranged from 7 to 23 years and for women, from 10 to 30 years.”
§ Gait Speed and Survival in Older Adults > RESULTS
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“There were substantial numbers of African American (n=3852) and Hispanic (n=2650) participants.”
§ Gait Speed and Survival in Older Adults > RESULTS
Strength:plain· not yet calibratedn = 3,852Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
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“Mortality rates appear to be related to length of follow-up (Table 1).”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“Predicted survival based on age, sex, and gait speed was as accurate as predicted based on age, sex, use of mobility aids, and self-reported function or as age, sex, chronic conditions, smoking history, blood pressure, body mass index, and hospitalization.”
§ Gait Speed and Survival in Older Adults > Abstract > Results
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In the paper
“In women, the probability of 5-year survival remained greater than 0.5 until advanced age (eFigure 3B), but 10-year survival at age 75 years ranged from 0.34 to 0.92 and at age 80 years from 0.22 to 0.86 (eFigure 4B).”
§ Gait Speed and Survival in Older Adults > RESULTS
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“For the 3 levels of functional status (independent, difficulty with instrumental ADLs, and dependent in ADLs), the pooled HR per 0.1-m/s increase in gait speed for those who were independent was 0.92 (P= .005), for those with difficulty in instrumental activities was also 0.92 (P<.001) but was 0.94 (P=.02) among those dependent in ADLs.”
§ Gait Speed and Survival in Older Adults > RESULTS
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“The studies had a wide age range, including 1765 persons older than 85 years.”
§ Gait Speed and Survival in Older Adults > RESULTS
Strength:plain· not yet calibratedn = 1,765Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
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“There were consistent associations across studies, although given the large sample sizes, Q statistics were often statistically significant (details available in eFigure 1A–M available at http://www.jama.com).”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“Age-adjusted HRs by study ranged from 0.83 to 0.94 and all were significant (P<.001; Figure 1).”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“When dichotomized at a score of 100 into low and high activity, MrOS had consistent and statistically significant HRs for low (HR, 0.85; 95% CI, 0.81–0.88) and high (HR, 0.87; 95% CI, 0.84–0.90) physical”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“In the pooled sample, median survival in years for the age groups 65 through 74 years was 12.6 for men and 16.8 for women; for 75 through 84 years, 7.9 for men and 10.5 for women; and for 85 years or older, 4.6 for men and 6.4 years for women (eTable 3 available at http://www.jama.com).”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“Gait speed was associated with differences in the probability of survival at all ages in both sexes, but was especially informative after age 75 years.”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“There were 17 528 deaths; the overall 5-year survival rate was 84.8% (confidence interval [CI], 79.6%–88.8%)and 10-year survival rate was 59.7% (95%CI, 46.5%–70.6%).”
§ Gait Speed and Survival in Older Adults > Abstract > Results
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In the paper
“Further adjustment for sex, BMI, smoking status, systolic blood pressure, diseases, prior hospitalization, and self-reported health did not change the results (overall HR, 0.90; 95% CI, 0.89–0.91; P<.001).”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“In men, the probability of 5-year survival at age 85 ranged from 0.3 to 0.88 (eFigure 3A) and the probability of 10-year survival at age 75 years ranged from 0.18 to 0.86 (eFigure 4A).”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“Survival increased across the full range of gait speeds, with significant increments per 0.1 m/s.”
§ Gait Speed and Survival in Older Adults > Abstract > Results
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In the paper
“The 9 participating studies contributed a total of 34 485 participants (Table 1).”
§ Gait Speed and Survival in Older Adults > RESULTS
Strength:plain· not yet calibratedn = 34,485Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
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In the paper
“There were 17 528 total deaths across all studies, with rates varying from 18.40% to 91.87% in individual studies.”
§ Gait Speed and Survival in Older Adults > RESULTS
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
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In the paper
“In the Hispanic EPESE, the HR for low physical activity was significant (0.92; 95% CI, 0.88–0.96) but the HR for higher physical activity was not (0.99; 95% CI, 0.95–1.04).”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“Pooled HRs for all subgroups except functional status were consistently in the range of 0.81 to 0.92 and all were significant (P<.002).”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“C statistics for age, sex, and gait speed were greater than those for age, sex, and chronic diseases in 4 of 9 studies, approximately equivalent in 5 studies and inferior in no studies.”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“For 10-year survival, 6 studies had sufficient follow-up time to perform many of the analyses (Table 3).”
§ Gait Speed and Survival in Older Adults > RESULTS
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
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In the paper
“We assessed usual vs fast gait speed in the single study with both measures (Invecciare in Chianti18 study: usual, 0.727 [95% CI, 0.678–0.776]; fast, 0.684 [95% CI, 0.630–0.739]), suggesting that fast walks did not have an advantage in survival prediction over usual-paced walks.”
§ Gait Speed and Survival in Older Adults > RESULTS
Load-bearingStrength:hedged· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
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In the paper
“For these studies, gait speed, age, and sex yielded a C statistic (0.741) that was not significantly different (P=.78) from age, sex, mobility aids, and functional status (P=.75; Table 3).”
§ Gait Speed and Survival in Older Adults > RESULTS
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
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In the paper
“Gait speed added predictive ability to age and sex in 4 of 6 studies and in the pooled analysis.”
§ Gait Speed and Survival in Older Adults > RESULTS
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In the paper
“In our data, predicted life expectancy at the median for age and sex occurs at about 0.8 m/s; faster gait speeds predict life expectancy beyond the median.”
§ Gait Speed and Survival in Older Adults > COMMENT
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In the paper
“Gait speed has been recommended as a potentially useful clinical indicator of well-being among the older adults.14”
§ Gait Speed and Survival in Older Adults > Abstract > Conclusion
What the sources say
- Not matchedcites [14]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Strength:hedged· not yet calibratedTests✓ Asserted: passes✗ Checkable: fails✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it.
- Not matched
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In the paper
“Because physical activity measures were not sufficiently consistent across studies, effects could not be pooled.”
§ Gait Speed and Survival in Older Adults > RESULTS
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
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In the paper
“Gait speed could be considered a simple and accessible summary indicator of vitality because it integrates known and unrecognized disturbances in multiple organ systems, many of which affect survival.”
§ Gait Speed and Survival in Older Adults > COMMENT
Tests✓ Asserted: passes✗ Checkable: fails✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim. It may be too vague to check against evidence.
In the paper
“Only a few models assess overall predictive capacity using C statistics; the reported values are in the range found in the present study (published area under the curve range, 0.66–0.8261 vs this study, 0.717 and 0.737).”
§ Gait Speed and Survival in Older Adults > COMMENT
What the sources say
- Not matchedcites [61]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
- Not matched
In the paper
“Because gait speed can be assessed by nonprofessional staff using a 4-m walkway and a stopwatch,21 it is relatively simple to measure compared with many medical assessments.”
§ Gait Speed and Survival in Older Adults > COMMENT
What the sources say
- Not matchedcites [21]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
- Not matched
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In the paper
“Several authors have proposed that gait speeds faster than 1.0 m/s suggest healthier aging while gait speeds slower than 0.6 m/s increase the likelihood of poor health and function.7,21”
§ Gait Speed and Survival in Older Adults > COMMENT
What the sources say
- Not matchedcites [7]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [21]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Strength:hedged· not yet calibratedCausal:direct· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
- Not matched
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In the paper
“The participating study cohorts, while large and diverse, do not represent the universe of possible data.”
§ Gait Speed and Survival in Older Adults > COMMENT
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
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In the paper
“The strengths of this study are the very large sample of individual participant data from multiple diverse populations of community-dwelling elders who were followed up for many years and use of consistent measures of performance and outcome.”
§ Gait Speed and Survival in Older Adults > COMMENT
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Gait speed might help refine survival estimates in clinical practice or research because it is simple and informative.”
§ Gait Speed and Survival in Older Adults > COMMENT
Tests✓ Asserted: passes✗ Checkable: fails✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim. It may be too vague to check against evidence.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Although the gait speed–survival relationship seems continuous across the entire range, cut points may help interpretation.”
§ Gait Speed and Survival in Older Adults > COMMENT
Strength:hedged· not yet calibratedCausal:correlational· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
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In the paper
“Also, participants in these studies had no prior knowledge about the meaning of walking speed.”
§ Gait Speed and Survival in Older Adults > COMMENT
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✗ Based: failsProbably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
None of the sources cited for this claim could be matched to a paper in Crossref, so there is nothing to check it against.
In the paper
“Slowing gait may reflect both damaged systems and a high-energy cost of walking.13,39–54”
§ Gait Speed and Survival in Older Adults > COMMENT
What the sources say
- Not matchedcites [13]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [39]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [40]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [41]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [42]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [43]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [44]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [45]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [46]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [47]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
- Not matched
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Gait speed, age, and sex may offer the clinician tools for assessing expected survival to contribute to tailoring goals of care in older adults.”
§ Gait Speed and Survival in Older Adults > COMMENT
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“We were unable to assess the association of physical activity with survival in pooled analyses because measures of activity were highly variable across studies.”
§ Gait Speed and Survival in Older Adults > COMMENT
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
In the paper
“However, median years of survival in this study resemble estimates for US adults across the sex and age range assessed.62”
§ Gait Speed and Survival in Older Adults > COMMENT
What the sources say
- Not matchedcites [62]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
- Not matched
In the paper
“Only 1 of the 9 studies was based in clinical practice,21 and advanced dementia is rare in populations who are competent to consent for research.”
§ Gait Speed and Survival in Older Adults > COMMENT
What the sources say
- Not matchedcites [21]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passesIt may state two separate claims as one.
- Not matched
None of the sources cited for this claim could be matched to a paper in Crossref, so there is nothing to check it against.
In the paper
“Prior analyses used single cohorts and presented results as relative rather than absolute risk, as done herein.”
§ Gait Speed and Survival in Older Adults > COMMENT
What the sources say
- Not matchedcites [6]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [7]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [9]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [10]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [11]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [12]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [55]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [56]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Load-bearingStrength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesProbably not a substantial claim. It may state two separate claims as one.
- Not matched
None of the sources cited for this claim could be matched to a paper in Crossref, so there is nothing to check it against.
In the paper
“Some models use self-reported information but others also include physiological or performance data, for a total of 4 to more than 10 predictive factors.”
§ Gait Speed and Survival in Older Adults > COMMENT
What the sources say
- Not matchedcites [3]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [4]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [5]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [57]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [58]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [59]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [60]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
- Not matched
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“This study has the limitations of observational research; it cannot establish causal relationships and is vulnerable to various forms of healthy volunteer bias.”
§ Gait Speed and Survival in Older Adults > COMMENT
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The research studies analyzed herein used trained staff to measure gait speed. Staffin clinical settings would need initial training and may produce more variable results.”
§ Gait Speed and Survival in Older Adults > COMMENT
Strength:hedged· not yet calibratedCausal:conditional· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
In the paper
“Others propose one cutoff around 0.8 m/s.13”
§ Gait Speed and Survival in Older Adults > COMMENT
What the sources say
- Not matchedcites [13]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Strength:plain· not yet calibratedTests✗ Asserted: fails✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The authors may not put it forward as true. The paper’s conclusions may not depend on it.
- Not matched
None of the sources cited for this claim could be matched to a paper in Crossref, so there is nothing to check it against.
In the paper
“Long-distance walks have become accepted in some medical fields and may contribute information beyond short walks.66–68”
§ Gait Speed and Survival in Older Adults > COMMENT
What the sources say
- Not matchedcites [66]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [67]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [68]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Strength:hedged· not yet calibratedCausal:conditional· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
- Not matched
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The results found herein suggest that gait speed appears to be especially informative in older persons who report either no function all imitations or only difficulty with instrumental ADLs and may be less helpful for older adults who already report dependence in basic ADLs.”
§ Gait Speed and Survival in Older Adults > COMMENT
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passesIt may state two separate claims as one.
None of the sources cited for this claim could be matched to a paper in Crossref, so there is nothing to check it against.
In the paper
“Similarly, mortality prediction models have been developed.3–5,57–60”
§ Gait Speed and Survival in Older Adults > COMMENT
What the sources say
- Not matchedcites [3]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [4]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [5]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [57]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [58]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [59]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites [60]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Strength:plain· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
- Not matched
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“However, the longer distance and time to perform the test may limit feasibility in many clinical settings.”
§ Gait Speed and Survival in Older Adults > COMMENT
Strength:hedged· not yet calibratedCausal:conditional· not yet calibratedTests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passesProbably not a substantial claim. The paper’s conclusions may not depend on it.
The paper relies on this without support.
There are currently no well-established approaches to predicting life expectancy that incorporate health and function.
“There are currently no well-established approaches to predicting life expectancy that incorporate health and function, although several models have been developed from individual data sources.3–5”
The paper relies on this without support.
Survival estimates help individualize goals of care for geriatric patients.
“Survival estimates help individualize goals of care for geriatric patients, but life tables fail to account for the great variability in survival.”
The paper relies on this without support.
Advanced dementia is rare in populations who are competent to consent for research.
“Only 1 of the 9 studies was based in clinical practice,21 and advanced dementia is rare in populations who are competent to consent for research.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The Edmonton Frail Scale is a multi-dimensional assessment instrument that includes the TUGT, and a test for cognitive impairment (108). It is quick to administer (less than 5 minutes) and is valid, reliable and feasible for routine use by non-geriatricians”
From Frailty in elderly people (2013) · cites this paper as [108]
In the citing paper
“Moreover, gait speed was associated with survival in pooled analysis of individual data from 9 cohort studies (pooled HR per 0.1 m/s: 0.88, 95% CI: 0.87–0.90, P < 0.001) (78).”
From Health Consequences of Sarcopenic Obesity: A Narrative Review (2020) · cites this paper as [78]
In the citing paper
“including a significant association with survival at increments of 0.1 m/s.84”
In the citing paper
“accumulating evidence from both preclinical studies and recent human clinical trials strongly suggests that Mt have a key role in the pathogenesis of age-related functional decline, marked by slower walking speed.(Hiona and Leeuwenburgh 2008;Studenski, Perera, Patel, Rosano, Faulkner, Inzitari, Brach, Chandler, Cawthon, Connor, Nevitt, Visser, Kritchevsky, Badinelli, Harris, Newman, Cauley, Ferru”
From Successful aging: Advancing the science of physical independence in older adults (2015) · cites this paper as Studenski et al. 2011
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
SPPB estimate falls outside its confidence interval
MinorThe reported SPPB C statistic is 0.738, above the upper limit of its reported 95% confidence interval, 0.735.
“SPPB, 0.738”
“95% CI, 0.690–0.735”
Conflicting 10-year survival ranges at age 75
MinorThe abstract gives age-75 survival ranges of 19%-87% for men and 35%-91% for women. The results give 18%-86% and 34%-92%, respectively, for the same predicted outcome.
“At age 75, predicted 10-year survival across the range of gait speeds ranged from 19% to 87% in men and from 35% to 91% in women.”
“In men, the probability of 5-year survival at age 85 ranged from 0.3 to 0.88 (eFigure 3A) and the probability of 10-year survival at age 75 years ranged from 0.18 to 0.86 (eFigure 4A). In women, the probability of 5-year survival remained greater than 0.5 until advanced age (eFigure 3B), but 10-year survival at age 75 years ranged from 0.34 to 0.92”
Citations
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Items 201–300 of 4,516
Painter, P., & Roshanravan, B. (2013) · Current Opinion in Nephrology & Hypertension · doi:10.1097/mnh.0b013e328365b43a · Cited by 169
Kim, H., Suzuki, T., Saito, K., Yoshida, H., Kojima, N., Kim, M., Sudo, M., Yamashiro, Y., & Tokimitsu, I. (2012) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/j.1447-0594.2012.00923.x · Cited by 168
Yoon, D. H., Kang, D., Kim, H., Kim, J., Song, H. S., & Song, W. J. (2016) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/ggi.12784 · Cited by 179
Physical frailty after liver transplantation
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“This loss of muscle is called sarcopenia, and it is associated with a decrease in the ability to move, leading to morbidity and ultimately to mortality (2); indeed, a decrease in walking speed is one of the strongest predictors of mortality in humans, and this finding is associated with sarcopenia (3, 4).”
BackgroundAbility to sit and rise from the floor as a predictor of all-cause mortality
de Brito, L. B. B., Ricardo, D. R., de Araújo, D. S. M. S., Ramos, P. S., MYERS, J. N., & de Araújo, C. G. S. (2012) · European Journal of Preventive Cardiology · doi:10.1177/2047487312471759 · Cited by 166
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Physical Exercise in the Oldest Old
Valenzuela, P. L., Castillo‐García, A., Morales, J. S., Izquierdo, M., Serra‐Rexach, J. A., Santos‐Lozano, A., & Lucia, A. (2019) · Comprehensive Physiology · doi:10.1002/cphy.c190002 · Cited by 152
Travison, T. G., Basaria, S., Storer, T. W., Jette, A. M., Miciek, R., Farwell, W. R., Choong, K., Lakshman, K., Mazer, N. A., Coviello, A. D., et al. (2011) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glr100 · Cited by 160
Functional Impairment, Disability, and Frailty in Adults Aging with HIV-Infection
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Instrumental and Non-Instrumental Evaluation of 4-Meter Walking Speed in Older Individuals
Maggio, M. G., Ceda, G. P., Ticinesi, A., Vita, F. D., Gelmini, G., Costantino, C., Meschi, T., Kressig, R. W., Cesari, M., Fabi, M., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0153583 · Cited by 160
“Epidemiological studies addressing the reliability and validity of gait speed assessment in this agegroup indicate that this parameter is an independent predictor of a wide range of poor clinical outcomes in older persons, including falls [2], hospitalization/institutionalization [3], disability [4] and mortality [5].”
BackgroundFairhall, N., Sherrington, C., Kurrle, S. E., Lord, S. R., Lockwood, K., & Cameron, I. D. (2012) · BMC Medicine · doi:10.1186/1741-7015-10-120 · Cited by 167
Inflammatory Markers and Gait Speed Decline in Older Adults
Verghese, J., Holtzer, R., Oh‐Park, M., Derby, C. A., Lipton, R. B., & Wang, C. (2011) · The Journals of Gerontology Series A · doi:10.1093/gerona/glr099 · Cited by 155
Individual Characteristics and Physical Activity in Older Adults: A Systematic Review
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Age-Related Variation in Health Status after Age 60
Santoni, G., Angleman, S. B., Welmer, A., Mangialasche, F., Marengoni, A., & Fratiglioni, L. (2015) · PLoS ONE · doi:10.1371/journal.pone.0120077 · Cited by 160
Slowing gait and risk for cognitive impairment
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Self-citationSpatiotemporal and plantar pressure patterns of 1000 healthy individuals aged 3–101 years
McKay, M. J., Cartwright, J., Ferreira, P. H., Simić, M., Vanicek, N., Wojciechowski, E., Mudge, A. J., & Burns, J. (2017) · Gait & Posture · doi:10.1016/j.gaitpost.2017.07.004 · Cited by 155
Shimada, H., Makizako, H., Doi, T., Park, H., Tsutsumimoto, K., Verghese, J., & Suzuki, T. (2017) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2017.09.019 · Cited by 159
Mendes, T. D. A. B., Duarte, Y. A. D. O., Nunes, D. P., Lebrão, M. L., Naslavsky, M. S., Rodrigues, A. D. S., & Amaro, E. (2015) · BMC Geriatrics · doi:10.1186/s12877-015-0031-2 · Cited by 166
The Epidemiology of Sarcopenia
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Role of Gait Speed in the Assessment of Older Patients
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Intrinsic Capacity Predicts Negative Health Outcomes in Older Adults
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“Although it might seem overly specific and distant from political activity, gait speed has been shown to be a reliable indicator of hospitalization (Cesari et al. 2005) and mortality (Studentski et al. 2011) among older adults.”
BackgroundA Systematic Review of Thirty-One Assessment Tests to Evaluate Mobility in Older Adults
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“As well, a pooled analysis of individual data collected from 9 cohort studies affirmed the association between gait speed and survival in older adults [10].”
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“Gait speed is a simple measure to summarise the overall disease burden and disability.(33) 34 In brief, two pylons will be set 4 m apart and subjects instructed to walk at a usual pace.”
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“In fact, physical performance could be considered as a summary indicator of vitality because it integrates known and unrecognized disturbances in multiple organ systems such as heart, lungs, circulatory and musculoskeletal systems [40].”
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“Keywords Real‐world gait, Algorithms, DMOs, Validation, Wearable sensor, Walking, Cadence, SL, Digital health, Accelerometer Introduction The adverse consequences of physical mobility loss and the importance of preserving mobility to ensure healthy ageing are undeniable [1, 2].”
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Efficacy and Safety of Single-Dose Zoledronic Acid for Osteoporosis in Frail Elderly Women
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Polypharmacy in the Aging Patient
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Incremental Value of Gait Speed in Predicting Prognosis of Older Adults With Heart Failure
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Muscle strength mediates the relationship between mitochondrial energetics and walking performance
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“…slows with increasing age in older adults (Cunningham et al., 1982), and this metric of lower extremity performance is a strong predictor of disability, functional dependence, and mortality in the adult and older population (Guralnik et al., 1995; Studenski et al., 2011; Schrack et al., 2012).”
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“Similar to previous research (21,22), 20-m gait speed was converted to 6-m gait speed using a conversion formula derived using data from 1,342 individuals who completed both gait speed assessments at year 9:”
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“Balance and gait speed are the most widely used physical measurements for evaluating physical function since gait speed [82-84] and functional decline [85] are predictors of survival among elderly people.”
BackgroundAssociation of Dual Decline in Cognition and Gait Speed With Risk of Dementia in Older Adults
Collyer, T. A., Murray, A. M., Woods, R. L., Storey, E., Chong, T. T. ‐., Ryan, J. L., Orchard, S. G., Brodtmann, A. G., Srikanth, V. K., Shah, R. C., et al. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2022.14647 · Cited by 137
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“In older adults, both grip strength [94] and gait speed [95,96] are strong predictors of all-cause mortality.”
BackgroundPhysical function as a prognostic biomarker among cancer survivors
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The Role of Energetic Cost in the Age‐Related Slowing of Gait Speed
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Berry Fruit Enhances Beneficial Signaling in the Brain
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Gait Speed Predicts 30-Day Mortality After Transcatheter Aortic Valve Replacement
Alfredsson, J., Stebbins, A. S., Brennan, J. M., Matsouaka, R., Afilalo, J., Peterson, E. D., Vemulapalli, S., Rumsfeld, J. S., Shahian, D. M., Mack, M. J., et al. (2016) · Circulation · doi:10.1161/circulationaha.115.020279 · Cited by 133
“92 m/s.(10) In elderly patients with heart failure(12) and those undergoing cardiac surgery,(13) the median gait speed is reported to be 0.”
BackgroundSarcopenia and cognitive impairment in elderly women: results from the EPIDOS cohort
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“The improvement in gait speed may be important, as gait speed is a strong predictor not only for falls [11] but also for survival [39,40].”
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Cognition and gait show a distinct pattern of association in the general population
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Metadata
- Authors
- Studenski, S.
- Affiliations
- Universitat Autònoma de Barcelona (ES)
- Corresponding author
- Studenski, Stephanie
- ORCID
- Studenski, Stephanie
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2011-01-05
- Volume
- 305
- Issue
- 1
- Pages
- 50
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- PMC
- PMC3080184
- OpenAlex
- W2159296038
- Semantic Scholar
- 25de2f67035336224c9f1e37f58c5b531d34b9ed
- Cited by
- 4,558
- References
- 73
- Citations by year
- 2026: 377 · 2025: 333 · 2024: 267 · 2023: 311 · 2022: 355 · 2021: 399 · 2020: 389 · 2019: 358 · 2018: 272 · 2017: 301 · 2016: 255 · 2015: 273 · 2014: 243 · 2013: 184 · 2012: 166
- FWCI
- 100.86
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- VU Research Portal (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- D-Scholarship@Pitt (University of Pittsburgh) (acceptedVersion)
- Pure Amsterdam UMC (submittedVersion)
- Radboud Repository (Radboud University) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- National Institutes of Health (UL1TR000005)
- National Institute on Aging (AG023641, AG 024827, K07AG023641, P30AG024827, P30AG021332)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
- Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
- Keywords
- walking speed, survival, older adults, life expectancy, physical performance, mortality prediction, goals of care, community-dwelling older adults
- MeSH terms
- Aged, Female, Gait, Humans, Life Expectancy, Male, United States, Cohort Studies, Geriatric Assessment, Survival Analysis
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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