Biochemistry, cell biology and molecular biology of lipids ofSaccharomyces cerevisiae

Regulation of the mevalonate pathway

Goldstein, J. L., & Brown, M. S. (1990) · Nature · doi:10.1038/343425a0 · Cited by 5,394

PROTEIN PRENYLATION: GENES, ENZYMES, TARGETS, AND FUNCTIONS

Schafer, W. R., & Rine, J. (1992) · Annual Review of Genetics · doi:10.1146/annurev.ge.26.120192.001233 · Cited by 377

Genomic Expression Programs in the Response of Yeast Cells to Environmental Changes

Gasch, A. P., Spellman, P. T., Kao, C. M., Carmel-Harel, O., Eisen, M. B., Storz, G., Botstein, D., & Brown, P. O. (2000) · Molecular Biology of the Cell · doi:10.1091/mbc.11.12.4241 · Cited by 4,815

Hydrogen peroxide sensing and signaling

Veal, E. A., Day, A. M., & Morgan, B. A. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.03.016 · Cited by 1,604

Genome-Scale Reconstruction of the Saccharomyces cerevisiae Metabolic Network

Förster, J., Famili, I., Fu, P., Palsson, B. Ø., & Nielsen, J. (2003) · Genome Research · doi:10.1101/gr.234503 · Cited by 1,069

Exploration of Essential Gene Functions via Titratable Promoter Alleles

Mnaimneh, S., Davierwala, A. P., Haynes, J., Moffat, J., Peng, W.-T., Zhang, W., Yang, X., Pootoolal, J., Chua, G., Lopez, A., et al. (2004) · Cell · doi:10.1016/j.cell.2004.06.013 · Cited by 604

Electrospray Ionization Tandem Mass Spectrometry (Esi-Ms/Ms) Analysis of the Lipid Molecular Species Composition of Yeast Subcellular Membranes Reveals Acyl Chain-Based Sorting/Remodeling of Distinct Molecular Species En Route to the Plasma Membrane

Schneiter, R., Brügger, B., Sandhoff, R., Zellnig, G., Leber, A., Lampl, M., Athenstaedt, K., Hrastnik, C., Eder, S., Daum, G., et al. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.146.4.741 · Cited by 493

Cells have distinct mechanisms to maintain protection against different reactive oxygen species: Oxidative-stress-response genes

Thorpe, G. W., Fong, C. S., Alic, N., Higgins, V. J., & Dawes, I. W. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0305888101 · Cited by 450

Oxidative stress and its effects during dehydration

França, M. B., Panek, A. D., & Eleutherio, E. C. A. (2007) · Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2006.02.030 · Cited by 422

Laboratory evolution of copper tolerant yeast strains

Adamo, G. M., Brocca, S., Passolunghi, S., Salvato, B., & Lotti, M. (2012) · Microbial Cell Factories · doi:10.1186/1475-2859-11-1 · Cited by 392

DGAT2 Is a New Diacylglycerol Acyltransferase Gene Family

Lardizabal, K. D., Mai, J. T., Wagner, N. W., Wyrick, A., Voelker, T., & Hawkins, D. J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m106168200 · Cited by 371

Yeast lipid metabolism at a glance

Klug, L., & Daum, G. (2014) · FEMS Yeast Research · doi:10.1111/1567-1364.12141 · Cited by 349

The Hog1 Mitogen-Activated Protein Kinase Is Essential in the Oxidative Stress Response and Chlamydospore Formation in Candidaalbicans

Alonso-Monge, R., Navarro-García, F., Román, E., Negredo, A. I., Eisman, B., Nombela, C., & Pla, J. (2003) · Eukaryotic Cell · doi:10.1128/ec.2.2.351-361.2003 · Cited by 308

Stress Alters Rates and Types of Loss of Heterozygosity in Candida albicans

Forche, A., Abbey, D., Pisithkul, T., Weinzierl, M. A., Ringstrom, T., Bruck, D., Petersen, K., & Berman, J. (2011) · mBio · doi:10.1128/mbio.00129-11 · Cited by 234

Extensive In Vivo Metabolite-Protein Interactions Revealed by Large-Scale Systematic Analyses

Li, X., Gianoulis, T. A., Yip, K. Y., Gerstein, M., & Snyder, M. (2010) · Cell · doi:10.1016/j.cell.2010.09.048 · Cited by 237

Ergosterol is required for targeting of tryptophan permease to the yeast plasma membrane

Umebayashi, K., & Nakano, A. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200303088 · Cited by 230

Genomic Profiling of the Response of Candida albicans to Itraconazole Treatment Using a DNA Microarray

De Backer, M. D., Ilyina, T., Ma, X.-J., Vandoninck, S., Luyten, W. H. M. L., & Vanden Bossche, H. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.6.1660-1670.2001 · Cited by 211

Phylogenetic diversity of stress signalling pathways in fungi

Nikolaou, E., Agrafioti, I., Stumpf, M., Quinn, J., Stansfield, I., & Brown, A. J. (2009) · BMC Evolutionary Biology · doi:10.1186/1471-2148-9-44 · Cited by 206

Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen C.albicans

Uhl, M. A., Biery, M., Craig, N., & Johnson, A. D. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg256 · Cited by 191

Multiple Functions of Sterols in Yeast Endocytosis

Heese-Peck, A., Pichler, H., Zanolari, B., Watanabe, R., Daum, G., & Riezman, H. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-04-0186 · Cited by 190

Metabolic response to iron deficiency in Saccharomyces cerevisiae

Shakoury-Elizeh, M., Protchenko, O., Berger, A., Cox, J., Gable, K., Dunn, T. M., Prinz, W. A., Bard, M., & Philpott, C. C. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.091710 · Cited by 182

Adaptation of Saccharomyces cerevisiae to saline stress through laboratory evolution

DHAR, R., SÄGESSER, R., WEIKERT, C., YUAN, J., & WAGNER, A. (2011) · Journal of Evolutionary Biology · doi:10.1111/j.1420-9101.2011.02249.x · Cited by 165

Transcriptional Response of Saccharomyces cerevisiae to the Plasma Membrane-Perturbing Compound Chitosan

Zakrzewska, A., Boorsma, A., Brul, S., Hellingwerf, K. J., & Klis, F. M. (2005) · Eukaryotic Cell · doi:10.1128/ec.4.4.703-715.2005 · Cited by 161

Role of the non‐respiratory pathways in the utilization of molecular oxygen by Saccharomyces cerevisiae

Rosenfeld, E., & Beauvoit, B. (2003) · Yeast · doi:10.1002/yea.1026 · Cited by 149

Heme Levels Switch the Function of Hap1 of Saccharomyces cerevisiae between Transcriptional Activator and Transcriptional Repressor

Hickman, M. J., & Winston, F. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00887-07 · Cited by 137

Yeast Adapts to a Changing Stressful Environment by Evolving Cross-Protection and Anticipatory Gene Regulation

Dhar, R., Sägesser, R., Weikert, C., & Wagner, A. (2013) · Molecular Biology and Evolution · doi:10.1093/molbev/mss253 · Cited by 126

Genomewide Location Analysis of Candida albicans Upc2p, a Regulator of Sterol Metabolism and Azole Drug Resistance

Znaidi, S., Weber, S., Zin Al-Abdin, O., Bomme, P., Saidane, S., Drouin, S., Lemieux, S., De Deken, X., Robert, F., & Raymond, M. (2008) · Eukaryotic Cell · doi:10.1128/ec.00070-08 · Cited by 119

A Small Subpopulation of Blastospores in Candida albicans Biofilms Exhibit Resistance to Amphotericin B Associated with Differential Regulation of Ergosterol and β -1,6-Glucan Pathway Genes

Khot, P. D., Suci, P. A., Miller, R. L., Nelson, R. D., & Tyler, B. J. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00997-06 · Cited by 104

Pheromones Stimulate Mating and Differentiation via Paracrine and Autocrine Signaling in Cryptococcus neoformans

Shen, W.-C., Davidson, R. C., Cox, G. M., & Heitman, J. (2002) · Eukaryotic Cell · doi:10.1128/ec.1.3.366-377.2002 · Cited by 97

Impact of pitching rate on yeast fermentation performance and beer flavour

Verbelen, P. J., Dekoninck, T. M. L., Saerens, S. M. G., Van Mulders, S. E., Thevelein, J. M., & Delvaux, F. R. (2009) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-008-1779-5 · Cited by 93

Dynamics of neutral lipid storage and mobilization in yeast

Daum, G., Wagner, A., Czabany, T., & Athenstaedt, K. (2007) · Biochimie · doi:10.1016/j.biochi.2006.06.018 · Cited by 87

Survival in the Presence of Antifungals

Meyer, V., Damveld, R. A., Arentshorst, M., Stahl, U., van den Hondel, C. A. M. J. J., & Ram, A. F. J. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m705856200 · Cited by 85

Phosphatidylserine transport by Ups2–Mdm35 in respiration-active mitochondria

Miyata, N., Watanabe, Y., Tamura, Y., Endo, T., & Kuge, O. (2016) · Journal of Cell Biology · doi:10.1083/jcb.201601082 · Cited by 83

Cloning, sequencing, expression and allelic sequence diversity of ERG3 (C-5 sterol desaturase gene) in Candida albicans

Miyazaki, Y., Geber, A., Miyazaki, H., Falconer, D., Parkinson, T., Hitchcock, C., Grimberg, B., Nyswaner, K., & Bennett, J. E. (1999) · Gene · doi:10.1016/s0378-1119(99)00263-2 · Cited by 71

Lipid raft involvement in yeast cell growth and death

Mollinedo, F. (2012) · Frontiers in Oncology · doi:10.3389/fonc.2012.00140 · Cited by 66

The Hog1 Mitogen-Activated Protein Kinase Mediates a Hypoxic Response in Saccharomyces cerevisiae

Hickman, M. J., Spatt, D., & Winston, F. (2011) · Genetics · doi:10.1534/genetics.111.128322 · Cited by 68

Antifungal activity of fluconazole in combination with lovastatin and their effects on gene expression in the ergosterol and prenylation pathways in Candida albicans

Song, J. L., Lyons, C. N., Holleman, S., Oliver, B. G., & White, T. C. (2003) · Medical Mycology · doi:10.1080/1369378031000137233 · Cited by 62

Skn7p is involved in oxidative stress response and virulence of Candida glabrata

Saijo, T., Miyazaki, T., Izumikawa, K., Mihara, T., Takazono, T., Kosai, K., Imamura, Y., Seki, M., Kakeya, H., Yamamoto, Y., et al. (2010) · Mycopathologia · doi:10.1007/s11046-009-9233-5 · Cited by 59

Adenylyl Cyclase and Protein Kinase A Play Redundant and Distinct Roles in Growth, Differentiation, Antifungal Drug Resistance, and Pathogenicity of Candida auris

Kim, J.-S., Lee, K.-T., Lee, M. H., Cheong, E., & Bahn, Y.-S. (2021) · mBio · doi:10.1128/mbio.02729-21 · Cited by 53

A hap1 mutation in a laboratory strain of Saccharomyces cerevisiae results in decreased expression of ergosterol-related genes and cellular ergosterol content compared to sake yeast

Tamura, K.-I., Gu, Y., Wang, Q., Yamada, T., Ito, K., & Shimoi, H. (2004) · Journal of Bioscience and Bioengineering · doi:10.1016/s1389-1723(04)00260-9 · Cited by 46

Disruption of mitochondrial function in Candida albicans leads to reduced cellular ergosterol levels and elevated growth in the presence of amphotericin B

Geraghty, P., & Kavanagh, K. (2003) · Archives of Microbiology · doi:10.1007/s00203-003-0530-y · Cited by 45

Functional characterization of the CgPGS1 gene reveals a link between mitochondrial phospholipid homeostasis and drug resistance in Candida glabrata

Batova, M., Borecka-Melkusova, S., Simockova, M., Dzugasova, V., Goffa, E., & Subik, J. (2008) · Current Genetics · doi:10.1007/s00294-008-0187-9 · Cited by 31

Cloning and sequencing of the Candida albicans C‐4 sterol methyl oxidase gene (ERG25) and expression of an ERG25 conditional lethal mutation in Saccharomyces cerevisiae

Kennedy, M. A., Johnson, T. A., Lees, N. D., Barbuch, R., Eckstein, J. A., & Bard, M. (2000) · Lipids · doi:10.1007/s11745-000-0521-2 · Cited by 29

Linkage between genes involved in azole resistance and ergosterol biosynthesis

Moye-Rowley, W. S. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1008819 · Cited by 29

Aft2, a Novel Transcription Regulator, Is Required for Iron Metabolism, Oxidative Stress, Surface Adhesion and Hyphal Development in Candida albicans

Xu, N., Cheng, X., Yu, Q., Qian, K., Ding, X., Liu, R., Zhang, B., Xing, L., & Li, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062367 · Cited by 24