Noncoding RNA s in disease

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993) · Cell · doi:10.1016/0092-8674(93)90529-y · Cited by 12,948 · see citing works

A microRNA expression signature of human solid tumors defines cancer gene targets

Volinia, S., Calin, G. A., Liu, C.-G., Ambs, S., Cimmino, A., Petrocca, F., Visone, R., Iorio, M., Roldo, C., Ferracin, M., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510565103 · Cited by 5,697 · see citing works

Long non-coding RNAs: insights into functions

Mercer, T. R., Dinger, M. E., & Mattick, J. S. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2521 · Cited by 5,654 · see citing works

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

Gupta, R. A., Shah, N., Wang, K., Kim, J., Horlings, H. M., Wong, D. J., Tsai, M.-C., Hung, T., Argani, P., Rinn, J. L., et al. (2010) · Nature · doi:10.1038/nature08975 · Cited by 5,203 · see citing works

Origins and Mechanisms of miRNAs and siRNAs

Carthew, R. W., & Sontheimer, E. J. (2009) · Cell · doi:10.1016/j.cell.2009.01.035 · Cited by 5,023 · see citing works

MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

Rupaimoole, R., & Slack, F. J. (2017) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2016.246 · Cited by 4,741 · see citing works

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

Wightman, B., Ha, I., & Ruvkun, G. (1993) · Cell · doi:10.1016/0092-8674(93)90530-4 · Cited by 4,292 · see citing works

Frequent deletions and down-regulation of micro- RNA genes <i>miR15</i> and <i>miR16</i> at 13q14 in chronic lymphocytic leukemia

Calin, G. A., Dumitru, C. D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., Aldler, H., Rattan, S., Keating, M., Rai, K., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242606799 · Cited by 4,269 · see citing works

Metazoan MicroRNAs

Bartel, D. P. (2018) · Cell · doi:10.1016/j.cell.2018.03.006 · Cited by 3,751 · see citing works

Unique features of long non-coding RNA biogenesis and function

Quinn, J. J., & Chang, H. Y. (2015) · Nature Reviews Genetics · doi:10.1038/nrg.2015.10 · Cited by 3,653 · see citing works

miR-15 and miR-16 induce apoptosis by targeting BCL2

Cimmino, A., Calin, G. A., Fabbri, M., Iorio, M. V., Ferracin, M., Shimizu, M., Wojcik, S. E., Aqeilan, R. I., Zupo, S., Dono, M., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506654102 · Cited by 3,510 · see citing works

The Transcriptional Landscape of the Mammalian Genome

Carninci, P., Kasukawa, T., Katayama, S., Gough, J., Frith, M. C., Maeda, N., Oyama, R., Ravasi, T., Lenhard, B., Wells, C. A., et al. (2005) · Science · doi:10.1126/science.1112014 · Cited by 3,492 · see citing works

Biogenesis of small RNAs in animals

Kim, V. N., Han, J., & Siomi, M. C. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2632 · Cited by 3,181 · see citing works

Identification of tissue-specific microRNAs from mouse

Lagos-Quintana, M., Rauhut, R., Yalcin, A., Meyer, J., Lendeckel, W., & Tuschl, T. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00809-6 · Cited by 2,859 · see citing works

c-Myc-regulated microRNAs modulate E2F1 expression

O’Donnell, K. A., Wentzel, E. A., Zeller, K. I., Dang, C. V., & Mendell, J. T. (2005) · Nature · doi:10.1038/nature03677 · Cited by 2,812 · see citing works

Switching from Repression to Activation: MicroRNAs Can Up-Regulate Translation

Vasudevan, S., Tong, Y., & STEITZ, J. A. (2007) · Science · doi:10.1126/science.1149460 · Cited by 2,806 · see citing works

The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation

Chen, J., Mandel, E. M., Thomson, J. M., Wu, Q., Callis, T. E., Hammond, S. M., Conlon, F. L., & Wang, D.-Z. (2005) · Nature Genetics · doi:10.1038/ng1725 · Cited by 2,763 · see citing works

A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA

Cesana, M., Cacchiarelli, D., Legnini, I., Santini, T., Sthandier, O., Chinappi, M., Tramontano, A., & Bozzoni, I. (2011) · Cell · doi:10.1016/j.cell.2011.09.028 · Cited by 2,554 · see citing works

Long Noncoding RNAs: Cellular Address Codes in Development and Disease

Batista, P. J., & Chang, H. Y. (2013) · Cell · doi:10.1016/j.cell.2013.02.012 · Cited by 2,531 · see citing works

The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

Tripathi, V., Ellis, J. D., Shen, Z., Song, D. Y., Pan, Q., Watt, A. T., Freier, S. M., Bennett, C. F., Sharma, A., Bubulya, P. A., et al. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.08.011 · Cited by 2,223 · see citing works

MALAT-1, a novel noncoding RNA, and thymosin β4 predict metastasis and survival in early-stage non-small cell lung cancer

Ji, P., Diederichs, S., Wang, W., Böing, S., Metzger, R., Schneider, P. M., Tidow, N., Brandt, B., Buerger, H., Bulk, E., et al. (2003) · Oncogene · doi:10.1038/sj.onc.1206928 · Cited by 2,191 · see citing works

The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis

Wang, S., Aurora, A. B., Johnson, B. A., Qi, X., McAnally, J., Hill, J. A., Richardson, J. A., Bassel‐Duby, R., & Olson, E. N. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.07.002 · Cited by 1,825 · see citing works

Mass-spectrometry-based draft of the human proteome

Wilhelm, M., Schlegl, J., Hahne, H., Gholami, A. M., Lieberenz, M., Savitski, M. M., Ziegler, E., Butzmann, L., Gessulat, S., Marx, H., et al. (2014) · Nature · doi:10.1038/nature13319 · Cited by 1,820 · see citing works

MicroRNA-133 controls cardiac hypertrophy

Carè, A., Catalucci, D., Felicetti, F., Bonci, D., Addario, A., Gallo, P., Bang, M., Segnalini, P., Gu, Y., Dalton, N. D., et al. (2007) · Nature Medicine · doi:10.1038/nm1582 · Cited by 1,775 · see citing works

Identification of Mammalian microRNA Host Genes and Transcription Units

Rodriguez, A., Griffiths-Jones, S., Ashurst, J. L., & Bradley, A. (2004) · Genome Research · doi:10.1101/gr.2722704 · Cited by 1,732 · see citing works

Long Noncoding RNAs with Enhancer-like Function in Human Cells

Ørom, U. A., Derrien, T., Beringer, M., Gumireddy, K., Gardini, A., Bussotti, G., Lai, F., Zytnicki, M., Notredame, C., Huang, Q., et al. (2010) · Cell · doi:10.1016/j.cell.2010.09.001 · Cited by 1,721 · see citing works

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

Kota, J., Chivukula, R. R., O’Donnell, K. A., Wentzel, E. A., Montgomery, C. L., Hwang, H., Chang, T.-C., Vivekanandan, P., Torbenson, M. S., Clark, K. R., et al. (2009) · Cell · doi:10.1016/j.cell.2009.04.021 · Cited by 1,711 · see citing works

Predictive Effects of Circulating miR-221, miR-130a and miR-155 for Coronary Heart Disease: A Multi-Ethnic Study in China

Jia, Q.-W., Chen, Z.-H., Ding, X.-Q., Liu, J.-Y., Ge, P.-C., An, F.-H., Li, L.-H., Wang, L.-S., Ma, W.-Z., Yang, Z.-J., et al. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000478071 · Cited by 1,693 · see citing works

Antisense Transcription in the Mammalian Transcriptome

Katayama, S., Tomaru, Y., Kasukawa, T., Waki, K., Nakanishi, M., Nakamura, M., Nishida, H., Yap, C.-S., Suzuki, M., Kawai, J., et al. (2005) · Science · doi:10.1126/science.1112009 · Cited by 1,664 · see citing works

Control of Stress-Dependent Cardiac Growth and Gene Expression by a MicroRNA

van Rooij, E., Sutherland, L. B., Qi, X., Richardson, J. A., Hill, J. A., & Olson, E. N. (2007) · Science · doi:10.1126/science.1139089 · Cited by 1,648 · see citing works

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs

Okazaki, Y., Furuno, M., Kasukawa, T., Adachi, J., Bono, H. U., Kondo, S., Nikaido, I., Osato, N., Saito, R., Suzuki, H., et al. (2002) · Nature · doi:10.1038/nature01266 · Cited by 1,636 · see citing works

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

Ventura, A., Young, A. G., Winslow, M. M., Lintault, L., Meissner, A., Erkeland, S. J., Newman, J. J., Bronson, R. T., Crowley, D. G., Stone, J. R., et al. (2008) · Cell · doi:10.1016/j.cell.2008.02.019 · Cited by 1,592 · see citing works

MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship

Pasquinelli, A. E. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3162 · Cited by 1,587 · see citing works

RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts

Geisler, S., & Coller, J. (2013) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3679 · Cited by 1,451 · see citing works

Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase

Faghihi, M. A., Modarresi, F., Khalil, A. M., Wood, D. E., Sahagan, B. G., Morgan, T. E., Finch, C. E., St. Laurent III, G., Kenny, P. J., & Wahlestedt, C. (2008) · Nature Medicine · doi:10.1038/nm1784 · Cited by 1,416 · see citing works

Delivery of MicroRNA-126 by Apoptotic Bodies Induces CXCL12-Dependent Vascular Protection

Zernecke, A., Bidzhekov, K., Noels, H., Shagdarsuren, E., Gan, L., Denecke, B., Hristov, M., Koeppel, T. A., Nazari-Jahantigh, M., Lutgens, E., et al. (2009) · Science Signaling · doi:10.1126/scisignal.2000610 · Cited by 1,335 · see citing works

The let-7 family of microRNAs

Roush, S. F., & Slack, F. J. (2008) · Trends in Cell Biology · doi:10.1016/j.tcb.2008.07.007 · Cited by 1,332 · see citing works

lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3′ UTRs via Alu elements

Gong, C., & Maquat, L. E. (2011) · Nature · doi:10.1038/nature09701 · Cited by 1,261 · see citing works

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

Xiao, C., Srinivasan, L., Calado, D. P., Patterson, H. C., Zhang, B., Wang, J., Henderson, J., Kutok, J. L., & Rajewsky, K. (2008) · Nature Immunology · doi:10.1038/ni1575 · Cited by 1,225 · see citing works

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/β-secretase expression

Hébert, S. S., Horré, K., Nicolaï, L., Papadopoulou, A. S., Mandemakers, W., Silahtaroglu, A. N., Kauppinen, S., Delacourte, A., & De Strooper, B. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0710263105 · Cited by 1,183 · see citing works

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43

Tollervey, J. R., Curk, T., Rogelj, B., Briese, M., Cereda, M., Kayikci, M., König, J., Hortobágyi, T., Nishimura, A. L., Župunski, V., et al. (2011) · Nature Neuroscience · doi:10.1038/nn.2778 · Cited by 1,165 · see citing works

Systematic Discovery of Xist RNA Binding Proteins

Chu, C., Zhang, Q. C., da Rocha, S. T., Flynn, R. A., Bharadwaj, M. C., Calabrese, J. M., Magnuson, T., Heard, É., & Chang, H. Y. (2015) · Cell · doi:10.1016/j.cell.2015.03.025 · Cited by 1,103 · see citing works

The Imprinted H19 LncRNA Antagonizes Let-7 MicroRNAs

Kallen, A. N., Zhou, X., Xu, J., Qiao, C., Ma, J., Yan, L., Lu, L., Liu, C., Yi, J.-S., Zhang, H., et al. (2013) · Molecular Cell · doi:10.1016/j.molcel.2013.08.027 · Cited by 1,049 · see citing works

Cardiac fibroblast–derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy

Bang, C., Bátkai, S., Dangwal, S., Gupta, S. K., Foinquinos, A., Holzmann, A., Just, A., Remke, J., Zimmer, K., Zeug, A., et al. (2014) · Journal of Clinical Investigation · doi:10.1172/jci70577 · Cited by 979 · see citing works

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma

Medina, P. P., Nolde, M., & Slack, F. J. (2010) · Nature · doi:10.1038/nature09284 · Cited by 971 · see citing works

Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in Eμ-miR155 transgenic mice

Costinean, S., Zanesi, N. A. O., Pekarsky, Y., Tili, E., Volinia, S., Heerema, N. A., & Croce, C. M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602266103 · Cited by 952 · see citing works

Long Noncoding RNA MALAT1 Regulates Endothelial Cell Function and Vessel Growth

Michalik, K., You, X. A., Manavski, Y., Doddaballapur, A., Zörnig, M., Braun, T. W., John, D., Ponomareva, Y., Chen, W., Uchida, S., et al. (2014) · Circulation Research · doi:10.1161/circresaha.114.303265 · Cited by 941 · see citing works

Differential Regulation of microRNAs by p53 Revealed by Massively Parallel Sequencing: miR-34a is a p53 Target That Induces Apoptosis and G1-arrest

Tarasov, V., Jung, P., Verdoodt, B., Lodygin, D., Epanchintsev, A., Menssen, A., Meister, G., & Hermeking, H. (2007) · Cell Cycle · doi:10.4161/cc.6.13.4436 · Cited by 922 · see citing works

The Lin28/let-7 axis regulates glucose metabolism

Zhu, H., Shyh-Chang, N., Segrè, A., Shinoda, G., Shah, S. P., Einhorn, W. S., Takeuchi, A., Engreitz, J. M., Hagan, J., Kharas, M., et al. (2011) · Cell · doi:10.1016/j.cell.2011.08.033 · Cited by 907 · see citing works

MicroRNAs in the Human Heart

Thum, T., Galuppo, P., Wolf, C., Fiedler, J., Kneitz, S., Laake, L. W. V., Doevendans, P. A., Mummery, C. L., Borlak, J. T., Haverich, A., et al. (2007) · Circulation · doi:10.1161/circulationaha.107.687947 · Cited by 890 · see citing works

MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice

Callis, T. E., Pandya, K., Seok, H., Tang, R., Tatsuguchi, M., Huang, Z., Chen, J., Deng, Z., Gunn, B. M., Shumate, J., et al. (2009) · Journal of Clinical Investigation · doi:10.1172/jci36154 · Cited by 861 · see citing works

Activating RNAs associate with Mediator to enhance chromatin architecture and transcription

Lai, F., Ørom, U. A., Cesaroni, M., Beringer, M., Taatjes, D. J., Blobel, G. A., & Shiekhattar, R. (2013) · Nature · doi:10.1038/nature11884 · Cited by 857 · see citing works

Lin28 promotes transformation and is associated with advanced human malignancies

Viswanathan, S. R., Powers, J. T., Einhorn, W. S., Hoshida, Y., Ng, T., Toffanin, S., O’Sullivan, M. J., Lü, J., Phillips, L. A., Lockhart, V. L., et al. (2009) · Nature Genetics · doi:10.1038/ng.392 · Cited by 816 · see citing works

miR-133 and miR-30 Regulate Connective Tissue Growth Factor

Duisters, R. F. J. J., Tijsen, A. J., Schroen, B. L. M., Leenders, J. J., Lentink, V., van der Made, I., Hérias, V., van Leeuwen, R. E. W., Schellings, M. W. M., Barenbrug, P. J. C., et al. (2008) · Circulation Research · doi:10.1161/circresaha.108.182535 · Cited by 816 · see citing works

MicroRNA-Mediated In Vitro and In Vivo Direct Reprogramming of Cardiac Fibroblasts to Cardiomyocytes

Jayawardena, T. M., Egemnazarov, B., Finch, E., Zhang, L., Payne, J., Pandya, K., Zhang, Z., Rosenberg, P. B., Mirotsou, M., & Dzau, V. J. (2012) · Circulation Research · doi:10.1161/circresaha.112.269035 · Cited by 775 · see citing works

Long Noncoding RNA MALAT1 Controls Cell Cycle Progression by Regulating the Expression of Oncogenic Transcription Factor B-MYB

Tripathi, V., Shen, Z., Chakraborty, A., Giri, S., Freier, S. M., Wu, X., Zhang, Y., Gorospe, M., Prasanth, S. G., Lal, A., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003368 · Cited by 753 · see citing works

Pervasive Transcription of the Human Genome Produces Thousands of Previously Unidentified Long Intergenic Noncoding RNAs

Hangauer, M. J., Vaughn, I. W., & McManus, M. T. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003569 · Cited by 738 · see citing works

The Functions of MicroRNAs: mRNA Decay and Translational Repression

Iwakawa, H., & Tomari, Y. (2015) · Trends in Cell Biology · doi:10.1016/j.tcb.2015.07.011 · Cited by 732 · see citing works

Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiationPreprint

Dinger, M. E., Amaral, P., Mercer, T. R., Pang, K. C., Bruce, S. J., Gardiner, B., Askarian-Amiri, M., Ru, K., Soldà, G., Simons, C., et al. (2008) · Genome Research · doi:10.1101/gr.078378.108 · Cited by 729 · see citing works

The <i>Evf-2</i> noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator

Feng, J., Bi, C., Clark, B. S., Mady, R., Shah, P., & Kohtz, J. D. (2006) · Genes &amp; Development · doi:10.1101/gad.1416106 · Cited by 712 · see citing works

The Long Noncoding RNAs NEAT1 and MALAT1 Bind Active Chromatin Sites

West, J. A., Davis, C. P., Sunwoo, H., Simon, M. D., Sadreyev, R. I., Wang, P. I., Tolstorukov, M. Y., & Kingston, R. E. (2014) · Molecular Cell · doi:10.1016/j.molcel.2014.07.012 · Cited by 705 · see citing works

The relationship between non‐protein‐coding DNA and eukaryotic complexity

Taft, R. J., Pheasant, M., & Mattick, J. S. (2007) · BioEssays · doi:10.1002/bies.20544 · Cited by 696 · see citing works

Dicer Dependent MicroRNAs Regulate Gene Expression and Functions in Human Endothelial Cells

Suárez, Y., Fernandez-Hernando, C. F., Pober, J. S., & Sessa, W. C. (2007) · Circulation Research · doi:10.1161/01.res.0000265065.26744.17 · Cited by 692 · see citing works

Development of a Lung Cancer Therapeutic Based on the Tumor Suppressor MicroRNA-34

Wiggins, J. F., Ruffino, L., Kelnar, K., Omotola, M., Patrawala, L., Brown, D., & Bader, A. G. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-0655 · Cited by 679 · see citing works

Targeting noncoding RNAs in disease

Adams, B. D., Parsons, C., Walker, L., Zhang, W. C., & Slack, F. J. (2017) · Journal of Clinical Investigation · doi:10.1172/jci84424 · Cited by 672 · see citing works

Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation

Modarresi, F., Faghihi, M. A., López-Toledano, M. A., Fatemi, R. P., Magistri, M., Brothers, S. P., van der Brug, M. P., & Wahlestedt, C. (2012) · Nature Biotechnology · doi:10.1038/nbt.2158 · Cited by 668 · see citing works

Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction

Ishii, N., Ozaki, K., Sato, H., Mizuno, H., Saito, S., Takahashi, A., Miyamoto, Y., Ikegawa, S., Kamatani, N., Hori, M., et al. (2006) · Journal of Human Genetics · doi:10.1007/s10038-006-0070-9 · Cited by 652 · see citing works

The H19 Non-Coding RNA Is Essential for Human Tumor Growth

Matouk, I., de-Groot, N., Mezan, S., Ayesh, S. K., Abu-lail, R., Hochberg, A., & Galun, E. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000845 · Cited by 649 · see citing works

The imprinted H19 noncoding RNA is a primary microRNA precursor

Cai, X., & Cullen, B. R. (2007) · RNA · doi:10.1261/rna.351707 · Cited by 642 · see citing works

Altered microRNA expression in human heart disease

Ikeda, S., Kong, S. W., Lü, J., Bisping, E. H., Zhang, H., Allen, P. D., Golub, T. R., Pieske, B. M., & Pu, W. T. (2007) · Physiological Genomics · doi:10.1152/physiolgenomics.00144.2007 · Cited by 618 · see citing works

Lin28A and Lin28B Inhibit let-7 MicroRNA Biogenesis by Distinct Mechanisms

Piskounova, E., Polytarchou, C., Thornton, J. E., LaPierre, R. J., Pothoulakis, C., Hagan, J. P., Iliopoulos, D., & Gregory, R. I. (2011) · Cell · doi:10.1016/j.cell.2011.10.039 · Cited by 611 · see citing works

The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy

Ucar, A., Gupta, S. K., Fiedler, J., Erikci, E., Kardasinski, M., Batkai, S., Dangwal, S., Kumarswamy, R., Bang, C., Holzmann, A., et al. (2012) · Nature Communications · doi:10.1038/ncomms2090 · Cited by 610 · see citing works

An E2F/miR-20a Autoregulatory Feedback Loop

Sylvestre, Y., Guire, V. D., Querido, E., Mukhopadhyay, U. K., Bourdeau, V., Major, F., Ferbeyre, G., & Chartrand, P. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m608939200 · Cited by 610 · see citing works

MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue

Roy, S., Khanna, S., Hussain, S.-R. A., Biswas, S., Azad, A., Rink, C. L., Gnyawali, S. C., Shilo, S., Nuovo, G. J., & Sen, C. K. (2009) · Cardiovascular Research · doi:10.1093/cvr/cvp015 · Cited by 609 · see citing works

The Long Noncoding RNA CHRF Regulates Cardiac Hypertrophy by Targeting miR-489

Wang, K., Liu, F., Zhou, L., Long, B., Yuan, S.-M., Wang, Y., Liu, C.-Y., Sun, T., Zhang, X.-J., & Li, P. (2014) · Circulation Research · doi:10.1161/circresaha.114.302476 · Cited by 581 · see citing works

Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure

Chen, J., Murchison, E. P., Tang, R., Callis, T. E., Tatsuguchi, M., Deng, Z., Rojas, M., Hammond, S. M., Schneider, M. D., Selzman, C. H., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0710228105 · Cited by 576 · see citing works

Evidence for natural antisense transcript-mediated inhibition of microRNA function

Faghihi, M., Zhang, M., Huang, J., Modarresi, F., van der Brug, M. P., Nalls, M., Cookson, M., Laurent, G. S. S., & Wahlestedt, C. (2010) · Genome Biology · doi:10.1186/gb-2010-11-5-r56 · Cited by 525 · see citing works

MicroRNAs in the p53 network: micromanagement of tumour suppression

Hermeking, H. (2012) · Nature Reviews Cancer · doi:10.1038/nrc3318 · Cited by 518 · see citing works

The H19 Long non-coding RNA in cancer initiation, progression and metastasis – a proposed unifying theory

Raveh, E., Matouk, I., Gilon, M., & Hochberg, A. (2015) · Molecular Cancer · doi:10.1186/s12943-015-0458-2 · Cited by 503 · see citing works

Inhibition of miR-15 Protects Against Cardiac Ischemic Injury

Hullinger, T. G., Montgomery, R. L., Seto, A. G., Dickinson, B., Semus, H. M., Lynch, J. M., Dalby, C. M., Robinson, K., Stack, C., Latimer, P. A., et al. (2011) · Circulation Research · doi:10.1161/circresaha.111.244442 · Cited by 502 · see citing works

MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function

Miñones-Moyano, E., Porta, S., Escaramís, G., Rabionet, R., Iraola‐Guzmán, S., Kagerbauer, B., Espinosa‐Parrilla, Y., Ferrer, I., Estivill, X., & Martı́, E. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr210 · Cited by 484 · see citing works

Emerging role of microRNA-21 in cancer

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CARL lncRNA inhibits anoxia-induced mitochondrial fission and apoptosis in cardiomyocytes by impairing miR-539-dependent PHB2 downregulation

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microRNA-155 Regulates Alpha-Synuclein-Induced Inflammatory Responses in Models of Parkinson Disease

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Long Noncoding RNA MALAT1 Promotes Aggressive Pancreatic Cancer Proliferation and Metastasis via the Stimulation of Autophagy

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LIN28B Promotes Colon Cancer Progression and Metastasis

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Clinical Outcome Prediction by MicroRNAs in Human Cancer: A Systematic Review

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MiR-26 enhances chemosensitivity and promotes apoptosis of hepatocellular carcinoma cells through inhibiting autophagy

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Expression of microRNA-34a in Alzheimer’s disease brain targets genes linked to synaptic plasticity, energy metabolism, and resting state network activity

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Altered Expression of the Long Noncoding RNA NEAT1 in Huntington’s Disease

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MicroRNA-29a Is a Candidate Biomarker for Alzheimer’s Disease in Cell-Free Cerebrospinal Fluid

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MicroRNA genes are frequently located near mouse cancer susceptibility loci

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miR-221/222 Targeting of Trichorhinophalangeal 1 (TRPS1) Promotes Epithelial-to-Mesenchymal Transition in Breast CancerA presentation from the Keystone Symposium on Epithelial Plasticity and Epithelial to Mesenchymal Transition, Vancouver, Canada, 21 to 26 January 2011. This Presentation also complements the Science Signaling Research Article by Stinson et al. published 14 June 2011.

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miR-221/222 Targets Adiponectin Receptor 1 to Promote the Epithelial-to-Mesenchymal Transition in Breast Cancer

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miR-106b aberrantly expressed in a double transgenic mouse model for Alzheimer's disease targets TGF-β type II receptor

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Expression of microRNA-208 is Associated With Adverse Clinical Outcomes in Human Dilated Cardiomyopathy

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MicroRNA-133 Modulates the β 1 -Adrenergic Receptor Transduction Cascade

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LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7Preprint

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Simvastatin ameliorate memory deficits and inflammation in clinical and mouse model of Alzheimer’s disease via modulating the expression of miR-106b

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miR-196a Ameliorates Phenotypes of Huntington Disease in Cell, Transgenic Mouse, and Induced Pluripotent Stem Cell Models

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The long noncoding RNA HOTAIR promotes Parkinson’s disease by upregulating LRRK2 expression

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Beta-asarone protects against MPTP-induced Parkinson’s disease via regulating long non-coding RNA MALAT1 and inhibiting α-synuclein protein expression

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Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

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miR-221/222 induces pancreatic cancer progression through the regulation of matrix metalloproteinases

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Knockdown of Long Non‐Coding RNA‐ZFAS1 Protects Cardiomyocytes Against Acute Myocardial Infarction Via Anti‐Apoptosis by Regulating miR‐150/CRP

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