Dynamics of the HPA Axis: A Systems Modeling Approach
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Previous mathematical models have simulated the dynamics of the HPA axis.
“Previous mathematical models have simulated the dynamics of the HPA axis”
From Subject-specific modeling of response to physical stress via hypothalamic-pituitary-adrenal and sympathoadrenal axes (2026) · cites this paper as [7]
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Modeling pulsativity in the hypothalamic–pituitary–adrenal hormonal axis
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An integrate-and-fire model for pulsatility in the neuroendocrine system
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Harris, H. A., Chan, D. M., Fix, L. E., Nicholson, B. D., & Acevedo, E. O. (2026) · PLOS One · doi:10.1371/journal.pone.0344981 · Cited by 2 · see citing works
Hormone oscillations in the HPA axis: dynamical diseases and beyond
MILTON, J. G., & Churilov, A. N. (2025) · Exploration of Endocrine and Metabolic Diseases · doi:10.37349/eemd.2025.101434 · Cited by 1 · see citing works
153Modeling pulsatile and diurnal rhythmicity of free and total cortisol
Churilov, A. N., & MILTON, J. G. (2026) · De Gruyter eBooks · doi:10.1515/9783112216620-013
- Authors
- Terry, J. R., Walker, J. J., Spiga, F., & Lightman, S. L.
- Venue
- Computational Neuroendocrinology
- Publisher
- Wiley
- Published
- 2016-04-11
- Pages
- 252-283
- OpenAlex
- W4255970883
- Cited by
- 5
- References
- 37
- Citations by year
- 2026: 2 · 2025: 1 · 2022: 1 · 2020: 1
- Type
- other
- Language
- en
- Open access
- closed
- Locations
- University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
- Funders
- Medical Research Council (MR/J008893/1, MR/J013811/1)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gene Regulatory Network Analysis
- Keywords
- hypothalamic-pituitary-adrenal axis, system modeling, stress response, glucocorticoids, feedback regulation
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