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When does human brain development end? Evidence of corpus callosum growth up to adulthood
Abstract
To locate structural changes in the brain accounting for the increasing effectiveness in cognition and skills that occurs at the final stage of behavioral development, we attempted to determine the age at which the corpus callosum completes its active growth period. We assessed the growth rate of the corpus callosum by measuring its area twice on midsagittal magnetic resonance imaging scans separated by a 2‐year interval, in a series of 90 subjects with a wide range of ages. We observed an increase in the size of the corpus callosum as long as human mentation expands, up to the middle 20s. Clinical and experimental data about the corpus callosum, together with the present findings, suggest that the corpus callosum is part of the highest order‐latest maturing neural network of the brain.
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“The corpus callosum, the dense mass of fibres that connects the two hemispheres of the brain, has also been found to undergo region-specific growth during adolescence and up until the mid-twenties (Barnea-Goraly et al., 2005;Giedd et al., 1999b;Pujol, Vendrell, Junque, Marti, & Josep, 1993).”
From Development of the adolescent brain: implications for executive function and social cognition (2006) · cites this paper as Pujol, Vendrell, Junque, Marti, & Josep, 1993
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Metadata
- Authors
- Pujol, J., Vendrell, P., Junqué, C., Martí‐Vilalta, J. L., & Capdevila, A.
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 1993-07
- Volume
- 34
- Issue
- 1
- Pages
- 71-75
- ISSN
- 0364-5134
- 1531-8249
- Cited by
- 295
- References
- 0
- Language
- en
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