Brief Outlook on Polymeric Nanoparticles, Micelles, Niosomes, Hydrogels and Liposomes: Preparative Methods and Action
Abstract
Polymeric nanoparticles, micelles, niosomes, hydrogels and liposomes represent effective drug carriers having huge potential for medical and pharmaceutical applications. These systems remain the most important area in medicinal chemistry research. The aforementioned biomaterials can effectively encapsulate and release diverse hydrophobic/hydrophilic therapeutic molecules including drugs and prodrugs. Applications of these carrier systems extend to nucleic acids, antibodies and proteins which could be released sustainably. Since these systems fall in the nano dimension, they are capable of enhancing the therapeutic efficacy of bioactive molecules besides enabling them to accumulate preferentially at the target site. Furthermore, these systems can protect the encapsulated drug from degradation, thereby increasing the therapeutic value of the drug candidate and reducing systemic toxicity. In this review, we illustrate the preparative methods and actions of these five drug delivery systems.
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Micelles are suitable for the delivery of water-insoluble and amphiphilic drugs.
“For example, micelles are suitable for the delivery of water-insoluble and amphiphilic drugs, and liposomes can increase the cellular uptake of a variety of drugs.14,15”
From Smart nanoparticles for cancer therapy (2023) · cites this paper as [14]
Liposomes can increase the cellular uptake of a variety of drugs.
“For example, micelles are suitable for the delivery of water-insoluble and amphiphilic drugs, and liposomes can increase the cellular uptake of a variety of drugs.14,15”
From Smart nanoparticles for cancer therapy (2023) · cites this paper as [14]
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- Authors
- Joy, R., George, J., & John, F.
- Affiliations
- Sacred Heart College (IN)
- Corresponding author
- George, Jinu
- John, Franklin
- Venue
- ChemistrySelect
- Publisher
- Wiley
- Published
- 2022-02-08
- Volume
- 7
- Issue
- 6
- ISSN
- 2365-6549 (ISSN-L)
- OpenAlex
- W4210903779
- Cited by
- 50
- References
- 152
- Citations by year
- 2026: 6 · 2025: 18 · 2024: 8 · 2023: 15 · 2022: 3
- FWCI
- 2.75
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- ChemistrySelect (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
- Keywords
- polymeric nanoparticles, micelles, niosomes, hydrogels, liposomes, drug delivery systems, drug carriers, drug encapsulation, controlled drug release, prodrugs, nucleic acid delivery, targeted drug delivery, drug protection from degradation, systemic toxicity reduction
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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