Selective depletion of cortical noradrenaline by anti-dopamine beta-hydroxylase-saporin impairs attentional function and enhances the effects of guanfacine in the rat

The Rat Brain in Stereotaxic Coordinates

Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585 · see citing works

Statistical Methods for Psychology.

Gudgeon, A. C., & Howell, D. C. (1994) · Journal of the Royal Statistical Society Series D (The Statistician) · doi:10.2307/2348956 · Cited by 8,277 · see citing works

The rat nervous system

Paxinos, G. (1985) · Cited by 3,715 · see citing works

The locus coeruleus–noradrenergic system: modulation of behavioral state and state-dependent cognitive processes

Berridge, C. W., & Waterhouse, B. D. (2003) · Brain Research Reviews · doi:10.1016/s0165-0173(03)00143-7 · Cited by 2,529 · see citing works

The 5-choice serial reaction time task: behavioural pharmacology and functional neurochemistry

Robbins, T. (2002) · Psychopharmacology · doi:10.1007/s00213-002-1154-7 · Cited by 1,282 · see citing works

Role of locus coeruleus in attention and behavioral flexibility

Aston-Jones, G., Rajkowski, J., & Cohen, J. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00140-7 · Cited by 900 · see citing works

The Cognitive Neuroscience of Attention

Melara, R. D. (2004) · Sage eBooks · doi:10.4135/9781483328768.n11 · Cited by 797 · see citing works

Effects of lesions to ascending noradrenergic neurones on performance of a 5-choice serial reaction task in rats; implications for theories of dorsal noradrenergic bundle function based on selective attention and arousal

Carli, M., Robbins, T. W., Evenden, J. L., & Everitt, B. J. (1983) · Behavioural Brain Research · doi:10.1016/0166-4328(83)90138-9 · Cited by 736 · see citing works

Enhanced and impaired attentional performance after infusion of D1 dopaminergic receptor agents into rat prefrontal cortex

Granon, S., Passetti, F., Thomas, K. L., Dalley, J. W., Everitt, B. J., & Robbins, T. W. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-03-01208.2000 · Cited by 546 · see citing works

Dissociable aspects of performance on the 5-choice serial reaction time task following lesions of the dorsal anterior cingulate, infralimbic and orbitofrontal cortex in the rat: differential effects on selectivity, impulsivity and compulsivity

Chudasama, Y., Passetti, F., Rhodes, S. E. V., Lopian, D., Desai, A., & Robbins, T. W. (2003) · Behavioural Brain Research · doi:10.1016/j.bbr.2003.09.020 · Cited by 518 · see citing works

The Cerebral Cortex of the Rat and Visual Attentional Function: Dissociable Effects of Mediofrontal, Cingulate, Anterior Dorsolateral, and Parietal Cortex Lesions on a Five-Choice Serial Reaction Time Task

Muir, J. L., Everitt, B. J., & Robbins, T. W. (1996) · Cerebral Cortex · doi:10.1093/cercor/6.3.470 · Cited by 503 · see citing works

Chemical neuromodulation of frontal-executive functions in humans and other animals

Robbins, T. W. (2000) · Experimental Brain Research · doi:10.1007/s002210000407 · Cited by 393 · see citing works

The alpha-2 adrenergic agonist guanfacine improves memory in aged monkeys without sedative or hypotensive side effects: evidence for alpha-2 receptor subtypes

Arnsten, A., Cai, J., & Goldman-Rakic, P. (1988) · The Journal of Neuroscience · doi:10.1523/jneurosci.08-11-04287.1988 · Cited by 391 · see citing works

Ribosome‐inactivating proteins up to date

Stirpe, F., & Barbieri, L. L. (1986) · FEBS Letters · doi:10.1016/0014-5793(86)80118-1 · Cited by 388 · see citing works

Noradrenergic modulation of cognitive function in rat medial prefrontal cortex as measured by attentional set shifting capability

Bluhm, M. D. L., & Morilak, D. A. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.09.031 · Cited by 325 · see citing works

Distinct Changes in Cortical Acetylcholine and Noradrenaline Efflux during Contingent and Noncontingent Performance of a Visual Attentional Task

Dalley, J. W., McGaughy, J., O'Connell, M. T., Cardinal, R. N., Levita, L., & Robbins, T. W. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-13-04908.2001 · Cited by 277 · see citing works

Amphetamine impairs the discriminative performance of rats with dorsal noradrenergic bundle lesions on a 5-choice serial reaction time task: New evidence for central dopaminergic-noradrenergic interactions

Cole, B. J., & Robbins, T. W. (1987) · Psychopharmacology · doi:10.1007/bf00216011 · Cited by 240 · see citing works

Noradrenergic, but not cholinergic, deafferentation of prefrontal cortex impairs attentional set-shifting

McGaughy, J., Ross, R. S., & Eichenbaum, H. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.01.064 · Cited by 226 · see citing works

Dopaminergic Modulation of Visual Attention and Working Memory in the Rodent Prefrontal Cortex

Chudasama, Y., & Robbins, T. W. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300490 · Cited by 225 · see citing works

The Frontal Cortex of the Rat and Visual Attentional Performance: Dissociable Functions of Distinct Medial Prefrontal Subregions

Passetti, F. (2002) · Cerebral Cortex · doi:10.1093/cercor/12.12.1254 · Cited by 223 · see citing works

Neuro-Psychopharmacology

Marley, E. (1962) · Psychopharmacology · doi:10.1007/bf00411372 · Cited by 221 · see citing works

Cortical cholinergic function and deficits in visual attentional performance in rats following 192 IgG–saporin-induced lesions of the medial prefrontal cortex

Dalley, J. W. (2004) · Cerebral Cortex · doi:10.1093/cercor/bhh052 · Cited by 191 · see citing works

Guanfacine, But Not Clonidine, Improves Planning and Working Memory Performance in Humans

Jäkälä, P. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(98)00127-4 · Cited by 188 · see citing works

Alpha-2 adrenergic agonists decrease distractibility in aged monkeys performing the delayed response task

Arnsten, A. F. T., & Contant, T. A. (1992) · Psychopharmacology · doi:10.1007/bf02245302 · Cited by 168 · see citing works

Central noradrenergic lesioning using anti-DBH-saporin: anatomical findings

Wrenn, C. C., Picklo, M. J., Lappi, D. A., Robertson, D., & Wiley, R. G. (1996) · Brain Research · doi:10.1016/s0006-8993(96)00855-4 · Cited by 160 · see citing works

Attentional effects of noradrenaline vary with arousal level: selective activation of thalamic pulvinar in humans

Coull, J. T., Jones, M. E. P., Egan, T. D., Frith, C., & Maze, M. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2003.12.022 · Cited by 150 · see citing works

Cholinergic Modulation of Visual Attention and Working Memory: Dissociable Effects of Basal Forebrain 192-IgG-saporin Lesions and Intraprefrontal Infusions of ScopolaminePreprint

Chudasama, Y., Dalley, J. W., Nathwani, F., Bouger, P., & Robbins, T. W. (2004) · Learning & Memory · doi:10.1101/lm.70904 · Cited by 144 · see citing works

Forebrain norepinephrine: role in controlled information processing in the rat.

Cole, B. J., & Robbins, T. W. (1992) · PubMed · Cited by 134 · see citing works

Adrenergic targets for the treatment of cognitive deficits in schizophrenia

Arnsten, A. F. T. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1724-3 · Cited by 127 · see citing works

Clonidine and diazepam have differential effects on tests of attention and learning

Coull, J. T., Middleton, H. C., Robbins, T. W., & Sahakian, B. J. (1995) · Psychopharmacology · doi:10.1007/bf02311180 · Cited by 118 · see citing works

The Neural Correlates of the Noradrenergic Modulation of Human Attention, Arousal and Learning

Coull, J. T., Frith, C., Dolan, R. J., Frackowiak, R. S. J., & Grasby, P. M. (1997) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1997.tb01635.x · Cited by 117 · see citing works

α2A- But not α2B/C-adrenoceptors modulate noradrenaline release in rat locus coeruleus: voltammetric data

Callado, L. F., & Stamford, J. A. (1999) · European Journal of Pharmacology · doi:10.1016/s0014-2999(98)00889-9 · Cited by 101 · see citing works

Lack of effects of guanfacine on executive and memory functions in healthy male volunteers

Müller, U., Clark, L., Lam, M. L., Moore, R. M., Murphy, C. L., Richmond, N. K., Sandhu, R. S., Wilkins, I. A., Menon, D. K., Sahakian, B. J., et al. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0078-4 · Cited by 73 · see citing works

Some electrophysiological and pharmacological properties of the cortical, noradrenergic projection of the locus coeruleus in the rat

Olpe, H. R., Glatt, A. F., Laszlo, J., & Schellenberg, A. (1980) · Brain Research · doi:10.1016/0006-8993(80)90251-6 · Cited by 69 · see citing works

Effects of medetomidine, an α-2 adrenoceptor agonist, and atipamezole, an α-2 antagonist, on spatial memory performance in adult and aged rats

Carlson, S., Tanila, H., Pia Rämä, A., Mecke, E., & Pertovaara, A. (1992) · Behavioral and Neural Biology · doi:10.1016/0163-1047(92)90327-z · Cited by 61 · see citing works

A partial noradrenergic lesion induced by DSP-4 increases extracellular noradrenaline concentration in rat frontal cortex: a microdialysis study in vivo

Hughes, Z. A., & Stanford, S. C. (1998) · Psychopharmacology · doi:10.1007/s002130050569 · Cited by 60 · see citing works

Treatment with the Noradrenergic Alpha-2 Agonist Clonidine, But Not Diazepam, Improves Spatial Working Memory in Normal Young Rhesus Monkeys

Franowicz, J. S. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00060-3 · Cited by 60 · see citing works

Determination of the somatodendritic α2-adrenoceptor subtype located in rat locus coeruleus that modulates cortical noradrenaline release in vivo

Mateo, Y., & Meana, J. J. (1999) · European Journal of Pharmacology · doi:10.1016/s0014-2999(99)00488-4 · Cited by 56 · see citing works

Alpha-2 Adrenoceptor Activation Inhibits Phencyclidine-Induced Deficits of Spatial Working Memory in Rats

Marrs, W., Kuperman, J. M., Avedian, T., Roth, R. H., & Jentsch, J. D. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300700 · Cited by 54 · see citing works

Evidence for the involvement of presynaptic alpha-2 adrenoceptors in the regulation of norepinephrine metabolism in the rat brain.

Curet, O., Dennis, T., & Scatton, B. (1987) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)22690-8 · Cited by 47 · see citing works

In vivo tonic modulation of the noradrenaline release in the rat cortex by locus coeruleus somatodendritic α2-adrenoceptors

Fernández‐Pastor, B., & Meana, J. J. (2002) · European Journal of Pharmacology · doi:10.1016/s0014-2999(02)01543-1 · Cited by 46 · see citing works

Effects of clonidine in the locus coeruleus on prefrontal- and hippocampal-dependent measures of attention and memory in the rat

Mair, R. D., Zhang, Y., Bailey, K. R., Toupin, M. M., & Mair, R. D. (2005) · Psychopharmacology · doi:10.1007/s00213-005-2263-x · Cited by 45 · see citing works

Characterization of noradrenaline release in the locus coeruleus of freely moving awake rats by in vivo microdialysis

Fernández‐Pastor, B., Mateo, Y., Gómez‐Urquijo, S., & Meana, J. J. (2005) · Psychopharmacology · doi:10.1007/s00213-005-2181-y · Cited by 39 · see citing works

Cholinergic and Noradrenergic Inputs to the Posterior Parietal Cortex Modulate the Components of Exogenous Attention.

Beane, M., & Marrocco, R. T. (2004) · Cited by 22 · see citing works

The Neuropsychopharmacology of Fronto-Executive Function: Monoaminergic Modulation

Robbins, T. W., & Arnsten, A. F. T. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135535 · Cited by 957 · see citing works

The neural and genetic basis of executive function: Attention, cognitive flexibility, and response inhibition

Logue, S. F., & Gould, T. J. (2014) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.08.007 · Cited by 477 · see citing works

The neuropharmacology of impulsive behaviour.

Pattij, T., & Vanderschuren, L. (2008) · TIPS - Trends in Pharmacological Sciences · doi:10.1016/j.tips.2008.01.002 · Cited by 480 · see citing works

Noradrenergic modulation of arousal

Berridge, C. W. (2008) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.10.013 · Cited by 368 · see citing works

Is there an inhibitory-response-control system in the rat? Evidence from anatomical and pharmacological studies of behavioral inhibition

Eagle, D. M., & Baunez, C. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.07.003 · Cited by 280 · see citing works

Differential regulation of fronto-executive function by the monoamines and acetylcholine

Robbins, T., & Roberts, A. (2007) · Cerebral Cortex · doi:10.1093/cercor/bhm066 · Cited by 279 · see citing works

Noradrenergic, but not cholinergic, deafferentation of prefrontal cortex impairs attentional set-shifting

McGaughy, J., Ross, R. S., & Eichenbaum, H. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.01.064 · Cited by 226 · see citing works

The utility of rat models of impulsivity in developing pharmacotherapies for impulse control disorders

Winstanley, C. A. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01323.x · Cited by 218 · see citing works

An inter-organ neural circuit for appetite suppression

Zhang, T., Perkins, M. H., Chang, H., Han, W., & de Araujo, I. E. (2022) · Cell · doi:10.1016/j.cell.2022.05.007 · Cited by 192 · see citing works

Noradrenergic modulation of cognition: Therapeutic implications

Chamberlain, S. R., & Robbins, T. W. (2013) · Journal of Psychopharmacology · doi:10.1177/0269881113480988 · Cited by 193 · see citing works

Prefrontal and monoaminergic contributions to stop-signal task performance in rats

Bari, A., Mar, A. C., Theobald, D. E., Elands, S. A., Oganya, K. C. N. A., Eagle, D. M., & Robbins, T. W. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.1543-11.2011 · Cited by 188 · see citing works

Prefrontal cortex and drug abuse vulnerability: Translation to prevention and treatment interventions

Perry, J. L., Joseph, J. E., Jiang, Y., Zimmerman, R. S., Kelly, T. H., Darna, M., Huettl, P., Dwoskin, L. P., & Bardo, M. T. (2011) · Brain Research Reviews · doi:10.1016/j.brainresrev.2010.09.001 · Cited by 180 · see citing works

Lesions of the dorsal noradrenergic bundle impair attentional set-shifting in the rat

Tait, D. S., Brown, V. J., Farovik, A., Theobald, D. E., Dalley, J. W., & Robbins, T. W. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05612.x · Cited by 179 · see citing works

Prefrontal cortex executive processes affected by stress in health and disease

Girotti, M., Adler, S. M., Bulin, S. E., Fucich, E. A., Paredes, D., & Morilak, D. A. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.07.004 · Cited by 176 · see citing works

Dissociable effects of monoamine reuptake inhibitors on distinct forms of impulsive behavior in rats

Baarendse, P. J. J., & Vanderschuren, L. J. M. J. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2576-x · Cited by 165 · see citing works

The Molecular Genetics of Executive Function: Role of Monoamine System Genes

Barnes, J. J. M., Dean, A. J., Nandam, L. S., O’Connell, R. G., & Bellgrove, M. A. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.12.040 · Cited by 163 · see citing works

Norepinephrine and serotonin are required for vagus nerve stimulation directed cortical plasticity

Hulsey, D. R., Shedd, C. M., Sarker, S. F., Kilgard, M. P., & Hays, S. A. (2019) · Experimental Neurology · doi:10.1016/j.expneurol.2019.112975 · Cited by 158 · see citing works

Noradrenergic Innervation of the Dorsal Medial Prefrontal Cortex Modulates Hypothalamo-Pituitary-Adrenal Responses to Acute Emotional Stress

Radley, J. J., Williams, B., & Sawchenko, P. E. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0552-08.2008 · Cited by 148 · see citing works

Atomoxetine reverses attentional deficits produced by noradrenergic deafferentation of medial prefrontal cortex

Newman, L. A., Darling, J., & McGaughy, J. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1097-8 · Cited by 137 · see citing works

Pharmacological Enhancement of Memory and Executive Functioning in Laboratory Animals

Floresco, S., & Jentsch, J. D. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.158 · Cited by 109 · see citing works

Evidence for Broad Versus Segregated Projections from Cholinergic and Noradrenergic Nuclei to Functionally and Anatomically Discrete Subregions of Prefrontal Cortex

Chandler, D. J., & Waterhouse, B. D. (2012) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2012.00020 · Cited by 99 · see citing works

Prefrontal Norepinephrine Determines Attribution of “High” Motivational Salience

Ventura, R., Latagliata, E. C., Morrone, C., Mela, I. L., & Puglisi‐Allegra, S. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003044 · Cited by 94 · see citing works

Immunotoxins Constructed with Ribosome-Inactivating Proteins and their Enhancers: A Lethal Cocktail with Tumor Specific Efficacy

Gilabert‐Oriol, R., Weng, A., von Mallinckrodt, B., Melzig, M. F., Fuchs, H., & Thakur, M. (2014) · Current Pharmaceutical Design · doi:10.2174/1381612820666140826153913 · Cited by 92 · see citing works

From the cell to the clinic: A comparative review of the partial D2/D3 receptor agonist and α2-adrenoceptor antagonist, piribedil, in the treatment of Parkinson's disease

Millan, M. J. (2010) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2010.06.002 · Cited by 91 · see citing works

The effect of lipopolysaccharide (LPS) on inflammatory markers in blood and brain and on behavior in individually-housed pigs

Nordgreen, J., Munsterhjelm, C., Aae, F., Popova, A., Boysen, P., Ranheim, B., Heinonen, M., Raszplewicz, J., Piepponen, P. T., Lervik, A., et al. (2018) · Physiology & Behavior · doi:10.1016/j.physbeh.2018.07.013 · Cited by 81 · see citing works

Blockade of noradrenaline re-uptake sites improves accuracy and impulse control in rats performing a five-choice serial reaction time tasks

Robinson, E. S. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2420-3 · Cited by 80 · see citing works

Performance Deficits of NK1 Receptor Knockout Mice in the 5-Choice Serial Reaction-Time Task: Effects of d-Amphetamine, Stress and Time of Day

Yan, T. C., Dudley, J., Weir, R. K., Grabowska, E., Peña‐Oliver, Y., Ripley, T. L., Hunt, S. P., Stephens, D., & Stanford, S. C. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017586 · Cited by 75 · see citing works

Dexmedetomidine may benefit cognitive function after laparoscopic cholecystectomy in elderly patients

CHEN, J., Yan, J., & Han, X.-P. (2012) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2012.811 · Cited by 68 · see citing works

Optogenetic silencing of locus coeruleus activity in mice impairs cognitive flexibility in an attentional set-shifting task

Janitzky, K., Lippert, M., Engelhorn, A., Tegtmeier, J., Goldschmidt, J., Heinze, H., & Ohl, F. W. (2015) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2015.00286 · Cited by 67 · see citing works

Brain microdialysate monoamines in relation to circadian rhythms, sleep, and sleep deprivation - a systematic review, network meta-analysis, and new primary data

Menon, J. M. L., Nolten, C., Achterberg, E. J. M., Joosten, R. N. J. M. A., Dematteis, M., Feenstra, M. G. P., Drinkenburg, W. H. (., & Leenaars, C. H. C. (2019) · Journal of Circadian Rhythms · doi:10.5334/jcr.174 · Cited by 57 · see citing works

Selective noradrenaline depletion impairs working memory and hippocampal neurogenesis

Coradazzi, M., Gulino, R., Fieramosca, F., Falzacappa, L. V., Riggi, M., & Leanza, G. (2016) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2016.08.012 · Cited by 57 · see citing works

Atomoxetine facilitates attentional set shifting in adolescent rats

Cain, R. E., Wasserman, M. C., Waterhouse, B. D., & McGaughy, J. A. (2011) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2011.04.003 · Cited by 55 · see citing works

Convergent pharmacological mechanisms in impulsivity and addiction: insights from rodent models

Jupp, B., & Dalley, J. W. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12787 · Cited by 56 · see citing works

Methylphenidate-induced impulsivity: pharmacological antagonism by β-adrenoreceptor blockade

Milstein, J. A., Dalley, J. W., & Robbins, T. W. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881108098146 · Cited by 56 · see citing works

Noradrenergic Hypothesis Linking Neurodegeneration-Based Cognitive Decline and Astroglia

Leanza, G., Gulino, R., & Zorec, R. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00254 · Cited by 54 · see citing works

Early Postnatal Manganese Exposure Causes Lasting Impairment of Selective and Focused Attention and Arousal Regulation in Adult Rats

Beaudin, S. A., Strupp, B. J., Strawderman, M. S., & Smith, D. R. (2016) · Environmental Health Perspectives · doi:10.1289/ehp258 · Cited by 53 · see citing works

The impact of cafeteria diet feeding on physiology and anxiety-related behaviour in male and female Sprague–Dawley rats of different ages

Warneke, W., Klaus, S., Fink, H., Langley‐Evans, S. C., & Voigt, J. (2013) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.11.016 · Cited by 52 · see citing works

Noradrenergic modulation of risk/reward decision making

Montes, D. R., Stopper, C. M., & Floresco, S. (2015) · Psychopharmacology · doi:10.1007/s00213-015-3904-3 · Cited by 50 · see citing works

Cognitive Impairment, Neuroimaging, and Alzheimer Neuropathology in Mouse Models of Down Syndrome

Hamlett, E. D., Boger, H. A., Ledreux, A., Kelley, C. M., Mufson, E. J., Falangola, M. F., Guilfoyle, D. N., Nixon, R. A., Patterson, D., Duval, N., et al. (2015) · Current Alzheimer Research · doi:10.2174/1567205012666150921095505 · Cited by 51 · see citing works

The Role of Guanfacine as a Therapeutic Agent to Address Stress-Related Pathophysiology in Cocaine-Dependent Individuals

Fox, H. C., & Sinha, R. (2014) · Advances in pharmacology · doi:10.1016/b978-0-12-420118-7.00006-8 · Cited by 46 · see citing works

On the improvement of inhibitory response control and visuospatial attention by indirect and direct adrenoceptor agonists

Pattij, T., Schetters, D., Schoffelmeer, A. N. M., & van Gaalen, M. M. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2405-2 · Cited by 46 · see citing works

Effects of atomoxetine and methylphenidate on performance of a lateralized reaction time task in rats

Jentsch, J. D., Aarde, S. M., & Seu, E. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1181-0 · Cited by 44 · see citing works

Modeling Deficits in Attention, Inhibition, and Flexibility in HAND

Moran, L. M., Booze, R. M., & Mactutus, C. F. (2014) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-014-9539-z · Cited by 38 · see citing works

Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in rats

Iqbal, Z., Lei, Z., Ramkrishnan, A. S., Liu, S., Hasan, M., Akter, M., Lam, Y. Y., & Li, Y. (2023) · Communications Biology · doi:10.1038/s42003-022-04405-6 · Cited by 33 · see citing works

Thyrotoropin receptor knockout changes monoaminergic neuronal system and produces methylphenidate-sensitive emotional and cognitive dysfunction.

Mouri, A., Hoshino, Y., Narusawa, S., Ikegami, K., Mizoguchi, H., Murata, Y., Yoshimura, T., & Nabeshima, T. (2014) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2014.05.021 · Cited by 26 · see citing works

Differential effects of chemogenetic inhibition of dopamine and norepinephrine neurons in the mouse 5-choice serial reaction time task

Fitzpatrick, C. M., Runegaard, A. H., Christiansen, S. H., Hansen, N. W., Jørgensen, S. H., McGirr, J. C., Ajenjo, A. D. D., Sørensen, A. T., Perrier, J., Petersen, A., et al. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.12.004 · Cited by 31 · see citing works

Noradrenaline involvement in basic and higher integrated REM sleep processes

Gottesmann, C. (2008) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2008.04.002 · Cited by 31 · see citing works

Neuropsychopharmacology and Neurogenetic Aspects of Executive Functioning: Should Reward Gene Polymorphisms Constitute a Diagnostic Tool to Identify Individuals at Risk for Impaired Judgment?

Bowirrat, A., Chen, T. J. H., Oscar‐Berman, M., Madigan, M. A., Chen, A. L., Bailey, J. A., Braverman, E. R., Kerner, M., Giordano, J., Morse, S. A., et al. (2012) · Molecular Neurobiology · doi:10.1007/s12035-012-8247-z · Cited by 30 · see citing works

Effects of variation in the human α2A‐ and α2C‐adrenoceptor genes on cognitive tasks and pain perception

Kohli, U., Muszkat, M., Sofowora, G. G., Harris, P. A., Friedman, E. A., Dupont, W. D., Scheinin, M., Wood, A. J. J., Stein, C., & Kurnik, D. (2009) · European Journal of Pain · doi:10.1016/j.ejpain.2009.04.003 · Cited by 30 · see citing works

Stress and Alcohol Cues Exert Conjoint Effects on Go and Stop Signal Responding in Male Problem Drinkers

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Benn, A., & Robinson, E. S. J. (2016) · Psychopharmacology · doi:10.1007/s00213-016-4458-8 · Cited by 19 · see citing works

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Zaehle, T., & Krauel, K. (2021) · Progress in brain research · doi:10.1016/bs.pbr.2021.03.001 · Cited by 17 · see citing works

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Lindgren, H. S., Öz, M. D., Bergqvist, F., Lane, E. L., & Dunnett, S. B. (2013) · Experimental Neurology · doi:10.1016/j.expneurol.2013.11.015 · Cited by 15 · see citing works

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Mei, X., Wang, L., Yang, B., & Li, X. (2021) · Psychopharmacology · doi:10.1007/s00213-021-05841-8 · Cited by 10 · see citing works

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Robinson, E. S. J. (2016) · Psychopathology Review · doi:10.5127/pr.034713 · Cited by 7 · see citing works

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Gottesmann, C. (2010) · International review of neurobiology · doi:10.1016/s0074-7742(10)92012-6 · Cited by 5 · see citing works

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Redding, Z. V., Chawla, P. A., & Sabol, K. E. (2019) · Psychopharmacology · doi:10.1007/s00213-019-05329-6 · Cited by 5 · see citing works

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Higgins, G. A., & Silenieks, L. B. (2022) · Current topics in behavioral neurosciences · doi:10.1007/7854_2022_341 · Cited by 4 · see citing works

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Gálosi, R., Petykó, Z., Kállai, V., Tóth, A., Ollmann, T., Péczely, L., Kovács, A., Berta, B., & Lénárd, L. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.02.016 · Cited by 3 · see citing works

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Liang, H.-B., He, W., Liu, Y., & Wang, H. (2024) · Journal of Pain Research · doi:10.2147/jpr.s443915 · Cited by 2 · see citing works

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Vollbrecht, P. J. (2010) · Cited by 2 · see citing works

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Posselt, L. P., Coll-Marquès, J., Ovrom, S., Jørgensen, S. H., Eliassen, S., Kliem, K., Müller, J., Dalley, J. W., Robbins, T. W., Herborg, F., et al. (2026) · Neuropsychopharmacology · doi:10.1038/s41386-026-02404-3 · Cited by 1 · see citing works

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Yazıcı, K., & Yazıcı, A. (2010) · Cited by 1 · see citing works

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Dennison, L. K. (2013) · UpSpace Institutional Repository (University of Pretoria)

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Geday, J. (2009)

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Oganya, N. A. (2011)

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Jentsch, J. D., Groman, S. M., James, A. S., & Seu, E. (2011) · Springer eBooks · doi:10.1007/978-1-4419-1268-8_3

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Cerpa, J.-C. (2019) · theses.fr (ABES) · doi:10.70675/d4f665b9z3943z4c88z9b4bzbf11cd7cf8d1

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Nehme, S. B. S. (2024) · theses.fr (ABES) · doi:10.70675/7ad70482z0961z4eebzbc86z84355cab1f1d

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Schmitt, O., Eipert, P., Maestro, R. T., Bellmann, M., Haase, S., Morawska, P., & Prathapan, V. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106943

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Dudley, J. (2013) · UCL Discovery (University College London)

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Moran, L. M. (2013) · Scholar Commons (University of South Carolina)

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Carli, M., Robbins, T. W., Evenden, J. L., & Everitt, B. J. (1983) · Behavioural Brain Research · doi:10.1016/0166-4328(83)90138-9 · Cited by 736 · see citing works

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Volnova, A. B., Kurzina, N. P., Belskaya, A. D., Gromova, A. A., Pelevin, A., Ptukha, M. A., Fesenko, Z. S., Ignashchenkova, A., & Gainetdinov, R. R. (2023) · Biomedicines · doi:10.3390/biomedicines11010222 · Cited by 13 · see citing works

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Kawaura, K., Karasawa, J.-I., Chaki, S., & Hikichi, H. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.05.044 · Cited by 29 · see citing works

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Harrison, A. A., Everitt, B. J., & Robbins, T. W. (1997) · Psychopharmacology · doi:10.1007/s002130050410 · Cited by 452 · see citing works