Modulating behavioral inhibition by tDCS combined with cognitive training
Abstract
Cognitive training is an effective tool to improve a variety of cognitive functions, and a small number of studies have now shown that brain stimulation accompanying these training protocols can enhance their effects. In the domain of behavioral inhibition, little is known about how training can affect this skill. As for transcranial direct current stimulation (tDCS), it was previously found that stimulation over the right inferior frontal gyrus (rIFG) facilitates behavioral inhibition performance and modulates its electrophysiological correlates. This study aimed to investigate this behavioral facilitation in the context of a learning paradigm by giving tDCS over rIFG repetitively over four consecutive days of training on a behavioral inhibition task (stop signal task (SST)). Twenty-two participants took part; ten participants were assigned to receive anodal tDCS (1.5 mA, 15 min), 12 were assigned to receive training but not active stimulation. There was a significant effect of training on learning and performance in the SST, and the integration of the training and rIFG-tDCS produced a more linear learning slope. Better performance was also found in the active stimulation group. Our findings show that tDCS-combined cognitive training is an effective tool for improving the ability to inhibit responses. The current study could constitute a step toward the use of tDCS and cognitive training as a therapeutic tool for cognitive control impairments in conditions such as attention-deficit hyperactivity disorder (ADHD) or schizophrenia.
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In healthy adults, tDCS over rIFC combined with inhibition training significantly improved inhibition performance in a Stop task relative to sham tDCS and to inhibition training alone.
“In healthy adults, for example, tDCS over rIFC combined with inhibition training significantly improved inhibition performance in a Stop task relative to sham tDCS (Cunillera et al., 2014) and to inhibition training alone (Ditye et al., 2012).”
From Cognitive Neuroscience of Attention Deficit Hyperactivity Disorder (ADHD) and Its Clinical Translation (2018) · cites this paper as Ditye et al., 2012
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- Authors
- Ditye, T., Jacobson, L., Walsh, V., & Lavidor, M.
- Affiliations
- University College London (GB)
- Bar-Ilan University (IL)
- Venue
- Experimental Brain Research
- Published
- 2012-04-25
- Volume
- 219
- Issue
- 3
- Pages
- 363-368
- ISSN
- 0014-4819 (ISSN-L)
- 1432-1106
- OpenAlex
- W2062880338
- Cited by
- 232
- References
- 38
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 11 · 2023: 10 · 2022: 12 · 2021: 13 · 2020: 25 · 2019: 17 · 2018: 24 · 2017: 18 · 2016: 33 · 2015: 28 · 2014: 18 · 2013: 12
- FWCI
- 9.30
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Experimental Brain Research (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Keywords
- behavioral inhibition, transcranial direct current stimulation, cognitive training, right inferior frontal gyrus, stop-signal task, response inhibition, cognitive control, attention deficit hyperactivity disorder, schizophrenia
- MeSH terms
- Adult, Behavior Therapy, Electric Stimulation Therapy, Female, Humans, Male, Neural Inhibition, Social Behavior Disorders, Teaching, Cognitive Behavioral Therapy, Young Adult
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