The DOI matches its Crossref record; 39 of the 40 references it cites were found in a registry or an index.
Valuable products from biotechnology of microalgae
Abstract
The biotechnology of microalgae has gained considerable importance in recent decades. Applications range from simple biomass production for food and feed to valuable products for ecological applications. For most of these applications, the market is still developing and the biotechnological use of microalgae will extend into new areas. Considering the enormous biodiversity of microalgae and recent developments in genetic engineering, this group of organisms represents one of the most promising sources for new products and applications. With the development of sophisticated culture and screening techniques, microalgal biotechnology can already meet the high demands of both the food and pharmaceutical industries.
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“Due to their simple cultivation with high protein content and nutritional value, Chlorella and Arthrospira platensis are at the forefront of the microalgal market [63,78].”
From Challenges in Functional Food Products with the Incorporation of Some Microalgae (2024) · cites this paper as [63]
In the citing paper
“Algae are produced in quantity and sold directly as food and nutrient supplements, while their processed products or extracts are used in biopharmaceuticals and cosmetics [5–7].”
In the citing paper
“The world energy crisis in the 1970s led to the identification of algae as renewable and sustainable sources for biofuels production, prompting the exploration of microalgae as a new field of research for fuels and other valuable products [10, 140].”
From The promising future of microalgae: Current status, challenges, and optimization of a sustainable and renewable industry for biofuels, feed, and other products (2018) · cites this paper as [140]
In the citing paper
“According to one estimate, about 5000 metric tons of dry algal biomass processed for bioproducts generates US$ 1.25 × 109 each year [140].”
From The promising future of microalgae: Current status, challenges, and optimization of a sustainable and renewable industry for biofuels, feed, and other products (2018) · cites this paper as [140]
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Items 201–300 of 1,012
Hydrothermal carbonization of microalgae II. Fatty acid, char, and algal nutrient products
Heilmann, S. M., Jader, L. R., Harned, L. A., Sadowsky, M. J., Schendel, F. J., Lefebvre, P. A., von Keitz, M. G., & Valentas, K. J. (2011) · Applied Energy · doi:10.1016/j.apenergy.2010.12.041 · Cited by 163
Advances in genetic engineering of marine algae
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“…system has been established in the genera Porphyra (Kuang et al., 1998, Zhang et al., 2010) whose cultivation currently provides a yearly turnover of approximately 1×109 US dollars (Pulz and Gross, 2004) and forms a mature algal industry for food, cosmetics, and other high value products.”
BackgroundSynthetic ecology – A way forward for sustainable algal biofuel production?
Kazamia, E., Aldridge, D. C., & Smith, A. G. (2012) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2012.03.022 · Cited by 159
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“Carbohydrates for production of chemicals, proteins for use as animal feed, and lipids for biodiesel, are some examples of such compounds (Benemann, 2013; Pulz and Gross, 2004).”
BackgroundNanoalgosomes: Introducing extracellular vesicles produced by microalgae
Adamo, G., Fierli, D., Romancino, D. P., Picciotto, S., Barone, M. E., Aranyos, A., Božič, D., Morsbach, S., Raccosta, S., Stanly, C., et al. (2021) · Journal of Extracellular Vesicles · doi:10.1002/jev2.12081 · Cited by 161
“…are actively researched worldwide to address strategic priorities, with a particular focus on biofuel generation, bioremediation developments and biosynthesis of high-added value biochemicals (Blanch, 2012; Khozin-Goldberg et al., 2016; Pulz & Gross, 2004; Sun et al., 2013; Yáñez-Mó et al., 2015).”
BackgroundDark fermentation biorefinery in the present and future (bio)chemical industry
Bastidas‐Oyanedel, J., Bonk, F., Thomsen, M. H., & Schmidt, J. E. (2015) · Reviews in Environmental Science and Bio/Technology · doi:10.1007/s11157-015-9369-3 · Cited by 164
“Astaxanthin, a carotenoid used as pigmentation source and antioxidant, estimated 2006 market price was 2500 USD $/kg (Jeon et al. 2006), with a market estimation of USD $150 9 106/year (Pulz and Gross 2004).”
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“(Pulz and Gross 2004).”
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Mutanda, T., Naidoo, D., Bwapwa, J. K., & Anandraj, A. (2020) · Frontiers in Energy Research · doi:10.3389/fenrg.2020.598803 · Cited by 160
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Isolation of Industrial Important Bioactive Compounds from Microalgae
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“Euglena gracilis Biomass Flocculation Health food Euglena (Japan) [77] Odontella aurita Fatty acids Health supplement InnovalG (France) [65]”
BackgroundMethodInfluentialOxygen transfer and evolution in microalgal culture in open raceways
Mendoza, J. L., Granados, M. R., de Godos, I., Acién, F. G., Molina, E., Heaven, S., & Banks, C. J. (2013) · Bioresource Technology · doi:10.1016/j.biortech.2013.03.127 · Cited by 160
Isochrysis galbana and Diacronema vlkianum biomass incorporation in pasta products as PUFA’s source
Fradique, M., Batista, A. P., Nunes, M. C., Gouveia, L., Bandarra, N. M., & Raymundo, A. (2012) · LWT · doi:10.1016/j.lwt.2012.05.006 · Cited by 156
“…much effort is being devoted to developing a commercially feasible technology to produce EPA and DHA directly from microalgaewhich are the primary producers of these u3 PUFA in the food chain (Barclay, Meager, & Abril, 1994; Lebeau & Robert, 2003; Molina Grima et al., 2003; Pulz & Gross, 2004).”
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Proteins from Microalgae for the Stabilization of Fluid Interfaces, Emulsions, and Foams
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Energy evaluation of algal cell disruption by high pressure homogenisation
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“Despite the vast potential for the commercialisation of algalderived products ranging from fuel, food and feed, (Becker, 2007; Pulz and Gross, 2004; Scott et al., 2010), accessing the intracellular components in a cost-effective manner remains a major challenge in process-scale operations.”
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Ahmad, A., & Ashraf, S. M. (2023) · Algal Research · doi:10.1016/j.algal.2023.103185 · Cited by 168
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Species and material considerations in the formation and development of microalgal biofilms
Irving, T. E., & Allen, D. G. (2011) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-011-3341-0 · Cited by 157
“Microalgae are currently produced industrially for a number of niche markets, such as aquaculture and nutraceuticals (Pulz and Gross 2004).”
BackgroundThe impact of environmental factors on carbon dioxide fixation by microalgae
Morales, M., Sánchez-García, L., & Revah, S. (2017) · FEMS Microbiology Letters · doi:10.1093/femsle/fnx262 · Cited by 159
Biodiesel production from microalgae using lipase-based catalysts: Current challenges and prospects
Mota, G. F., de Sousa, I. G., de Oliveira, A. L. B., Cavalcante, A. L. G., Moreira, K. D. S., Cavalcante, F. T. T., Souza, J. E. D. S., Falcão, Í. R. D. A., Rocha, T. G., Valério, R. B. R., et al. (2022) · Algal Research · doi:10.1016/j.algal.2021.102616 · Cited by 161
Biodiesel production from genetically engineered microalgae: Future of bioenergy in Iran
Tabatabaei, M., Tohidfar, M., Jouzani, G. S., Safarnejad, M. R., & Pazouki, M. (2011) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2010.12.004 · Cited by 155
Scenario analysis of large scale algae production in tubular photobioreactors
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Factors affecting production of beta-carotene from Dunaliella salina microalgae
Pourkarimi, S., Hallajisani, A., Alizadehdakhel, A., Nouralishahi, A., & Golzary, A. (2020) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2020.101771 · Cited by 154
Emerging Trends in Genetic Engineering of Microalgae for Commercial Applications
Grama, S. B., Liu, Z., & Li, J. (2022) · Marine Drugs · doi:10.3390/md20050285 · Cited by 164
“As an ancestor of plants with billions of years of evolutionary history, they distinctively adapted to extreme habitats and developed massive phylogenetic and biochemical diversity [1,2].”
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“, pharmaceuticals, nutraceuticals, additive/functional foods, natural medicine, and cosmetics, can be extracted from microalgal species [1,2].”
BackgroundSing, S. F., Isdepsky, A., Borowitzka, M. A., & Lewis, D. M. (2014) · Bioresource Technology · doi:10.1016/j.biortech.2014.03.010 · Cited by 153
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Extremophiles in biofuel synthesis
Barnard, D., Casanueva, A. I., Tuffin, M. I., & Cowan, D. A. (2010) · Environmental Technology · doi:10.1080/09593331003710236 · Cited by 148
“There are a large number of extremophilic microalgae, such as Cyanidium caldarium and Galdieria sulphuraria, which tolerate both high temperatures and low pH, having high growth rates at 50 °C and pH 1 [121,122].”
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“The rise of interest in these microscopic organisms for biotechnological applications is due to the unique biochemical features and their vast biodiversity, which to date is almost entirely unexploited [6].”
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Genetic engineering of microalgae for enhanced lipid production
Muñoz, C. F., Südfeld, C., Naduthodi, M. I. S., Weusthuis, R. A., Barbosa, M. J., Wijffels, R. H., & D’Adamo, S. (2021) · Biotechnology Advances · doi:10.1016/j.biotechadv.2021.107836 · Cited by 147
New horizons in culture and valorization of red microalgae
Gaignard, C., Gargouch, N., Dubessay, P., Delattre, C., Pierre, G., Laroche, C., Fendri, I., Abdelkafi, S., & Michaud, P. (2018) · Biotechnology Advances · doi:10.1016/j.biotechadv.2018.11.014 · Cited by 146
Algae as a sustainable energy source for biofuel production in Iran: A case study
Najafi, G., Ghobadian, B., & Yusaf, T. F. (2011) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2011.07.010 · Cited by 144
Xie, T., Xia, Y., Zeng, Y., Li, X., & Zhang, Y. (2017) · Bioresource Technology · doi:10.1016/j.biortech.2017.02.099 · Cited by 144
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Enhancing production of microalgal biopigments through metabolic and genetic engineering
Saini, D. K., Chakdar, H., Pabbi, S., & Shukla, P. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1533518 · Cited by 143
“It has been shown for Dunaliella salina and H. pluvialis that inhibition of lipid accumulation can stall the biosynthesis of b-carotene and astaxanthin as lipid serves as a metabolic sink for these two carotenoids (Zhekisheva et al. 2005; Rabbani et al. 1998).”
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“Background In recent years, mass production of microalgae has been extensively exploited for applications in the industry of food, aquaculture, and bioenergy, and especially for biodiesel production [1, 2].”
BackgroundGreen technology for the industrial production of biofuels and bioproducts from microalgae: A review
Tang, D. Y. Y., Yew, G. Y., Koyande, A. K., Chew, K. W., Vo, D.-V. N., & Show, P. L. (2020) · Environmental Chemistry Letters · doi:10.1007/s10311-020-01052-3 · Cited by 142
Techno-economic and Monte Carlo Probabilistic Analysis of Microalgae Biofuel Production System
Batan, L. Y., Graff, G. D., & Bradley, T. H. (2016) · Bioresource Technology · doi:10.1016/j.biortech.2016.07.085 · Cited by 140
“5 kg of algae-canola feed can replace 1 kg of fish feed (De Pauw et al., 1984; Lubzens et al., 1995; Metting, 1996; Pulz and Gross, 2004; Richmond, 2004).”
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Blanco, A. M., Moreno, J., Del Campo, J. A., Rivas, J., & Guerrero, M. G. (2007) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-006-0598-9 · Cited by 140
“Although Muriellopsis sp. cells develop under rather moderate conditions of pH, temperature, or salinity, the ability to sustain fast growth even under high irradiance confer to this strain a weed-like behavior, similar to the case of Chlorella.”
BackgroundMembrane applications for microalgae cultivation and harvesting: a review
Drexler, I. L. C., & Yeh, D. H. (2014) · Reviews in Environmental Science and Bio/Technology · doi:10.1007/s11157-014-9350-6 · Cited by 145
“2008) and 6 billion USD (Pulz and Gross 2004) in the microand macro-algae industries, respectively.”
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“For instance, to replace only a 5% of the US demand of fuel for transport it is necessary to produce more than 66,000 kt/ year of oil rich biomass (Chisti, 2007) while, the microalgae biomass market produces only 5 kt/year (Pulz and Gross, 2004).”
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“Microalgae are photosynthetic microorganisms that are valuable natural sources of products used in consumer goods and biotechnological applications [21].”
Microalgae for biofuel production and removal of heavy metals: a review
Pavithra, K. G., Kumar, P. S., Jaikumar, V., Vardhan, K. H., & SundarRajan, P. (2020) · Environmental Chemistry Letters · doi:10.1007/s10311-020-01046-1 · Cited by 144
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“Microalgae are single-celled photosynthetic organisms that have recently gained attention for their potential in biotechnology, including the production of biofuels, nutraceuticals such as omega-3 fatty acids, therapeutic proteins 3 , and fish and animal feed (Pulz and Gross, 2004; Spolaore et al., 2006; Rosenberg et…”
BackgroundMicroalgae, a Potential Natural Functional Food Source – a Review
Villarruel‐López, A., Ascencio, F., & Nuño, K. (2017) · Polish Journal of Food and Nutrition Sciences · doi:10.1515/pjfns-2017-0017 · Cited by 141
“Seaweeds have been used by humans for about 14,000 years and as food products by the Japanese and Chinese cultures for centuries; the Aztec population also collected and cultivated seaweeds [Dillehay et al., 2008; Mc Hugh, 2003; Pulz & Gross, 2004].”
BackgroundInfluentialMarine Cryptophytes Are Great Sources of EPA and DHA
Peltomaa, E., Johnson, M., & Taipale, S. (2017) · Marine Drugs · doi:10.3390/md16010003 · Cited by 137
“These three groups represent distinct phylogenetic branches in the eukaryotic tree of life relative to green algae [21,22], and, thus, likely produce unique cocktails of nutraceuticals.”
BackgroundEl-Sheekh, M. M., Hamouda, R. A., & Nizam, A. A. (2013) · International Biodeterioration & Biodegradation · doi:10.1016/j.ibiod.2012.12.015 · Cited by 136
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Gokhale, S. V., Jyoti, K. K., & Lele, S. S. (2008) · Bioresource Technology · doi:10.1016/j.biortech.2007.07.039 · Cited by 134
“Algal biomass is known to produce many valuable biomolecules such as b-carotene, atraxanthine, chlorophyll (Kshirsagar et al., 2002; Jin et al., 2003; Pulz and Gross, 2004; Macı́as-Sánchez et al., 2005).”
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Improving Microalgae for Biotechnology—From Genetics to Synthetic Biology
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Carbon dioxide utilization: A paradigm shift with CO2 economy
Gulzar, A., Gulzar, A., Ansari, M. B., He, F., Gai, S., & Yang, P. (2020) · Chemical Engineering Journal Advances · doi:10.1016/j.ceja.2020.100013 · Cited by 145
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“oenergy and environmental applications, including biohydrogen production [110-115], advanced CO2 sequestration [116], production of next generation biofuels [117-120], and various bioactive/value-added compounds [121-123].”
BackgroundAn overview on red algae bioactive compounds and their pharmaceutical applications
Aziz, E., Batool, R., Khan, M. U., Rauf, A., Akhtar, W., Heydari, M., Rehman, S., Shahzad, T., Malik, A. M., Mosavat, S. H., et al. (2020) · Journal of Complementary and Integrative Medicine · doi:10.1515/jcim-2019-0203 · Cited by 140
Growth of Spirulina platensis enhanced under intermittent illumination
Xue, S., Su, Z., & Cong, W. (2010) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2010.12.012 · Cited by 137
D'Adamo, S., Schiano di Visconte, G., Lowe, G., Szaub‐Newton, J., Beacham, T., Landels, A., Allen, M. J., Spicer, A., & Matthijs, M. (2019) · Plant Biotechnology Journal · doi:10.1111/pbi.12948 · Cited by 129
“In recent years, the heterokont algae have become increasingly attractive for biotechnology and metabolic engineering applications because of their high lipid content and existing production for aquaculture (Hamilton et al., 2016; Kroth, 2007a; Nrel 1998; Pulz and Gross, 2004; Wikfors and Ohno, 2001).”
Microalgae as Biostimulants: A New Approach in Agriculture
González-Pérez, B. K., Rivas-Castillo, A. M., Valdez-Calderón, A., & Gayosso-Morales, M. A. (2022) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-021-03192-2 · Cited by 128
“Additionally, value range pricing of microalgae biomass varies depending on location, product purity, and the market status (Pulz and Gross 2004).”
BackgroundSupercritical CO2 extraction of neutral lipids from microalgae: Experiments and modelling
Mouahid, A., Crampon, C., Toudji, S.-A. A., & Badens, E. (2013) · The Journal of Supercritical Fluids · doi:10.1016/j.supflu.2013.01.024 · Cited by 129
An overview of biological processes and their potential for CO 2 capture
Goli, A., Shamiri, A., Talaiekhozani, A., Eshtiaghi, N., Aghamohammadi, N., & Aroua, M. K. (2016) · Journal of Environmental Management · doi:10.1016/j.jenvman.2016.08.054 · Cited by 133
“Hence, it has a very high retail value, too (Pulz and Gross, 2004).”
BackgroundRasdi, N. W., & Qin, J. G. (2014) · Journal of Applied Phycology · doi:10.1007/s10811-014-0495-z · Cited by 136
“The products of microalgae have various applications, particularly in pharmaceuticals, cosmetics, biofuel production, and aquaculture (Pulz and Gross 2004; Rosenberg et al. 2008; Borowitzka 2013).”
Cyanobacteria—From the Oceans to the Potential Biotechnological and Biomedical Applications
Khalifa, S. A. M., Shedid, E. S., Saied, E. M., Jassbi, A. R., Jamebozorgi, F. H., Rateb, M. E., Du, M., Abdel‐Daim, M. M., Kai, G., Alhammady, M. A., et al. (2021) · Marine Drugs · doi:10.3390/md19050241 · Cited by 133
“In addition, they are used in production of bioplastics, water treatment [33], hydrogen production [142], cosmetics [40], forestry, animal feed [143], and application in nanobiotechnology [36], as illustrated in Figure 8.”
MethodRupprecht, J. (2009) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2009.02.008 · Cited by 127
Biorefinery of microalgae – opportunities and constraints for different production scenarios
Hariskos, I., & Posten, C. (2014) · Biotechnology Journal · doi:10.1002/biot.201300142 · Cited by 126
“Furthermore, microalgal polysaccharides find application as water-soluble lubricants and thickening agents such as agar [56, 57].”
BackgroundEnhanced Genetic Tools for Engineering Multigene Traits into Green Algae
Rasala, B. A., Chao, S.-S., Pier, M. M., Barrera, D. J., & Mayfield, S. P. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094028 · Cited by 126
Seghiri, R., Kharbach, M., & Essamri, A. (2019) · Journal of Food Quality · doi:10.1155/2019/3707219 · Cited by 133
“On the contrary, microalgae are an alternative food of natural antioxidants, which were more varied than those found in other terrestrial plants [6].”
BackgroundAlgae-derived hydrocolloids in foods: applications and health-related issues
Liao, Y.-C., Chang, C., Nagarajan, D., Chen, C., & Chang, J. (2021) · Bioengineered · doi:10.1080/21655979.2021.1946359 · Cited by 138
“Alginate, the main commercial phycocolloid, started gaining its industrial value in the early twentieth century [17,22].”
BackgroundZhang, T.-Y., Hu, H.-Y., Wu, Y.-H., Zhuang, L.-L., Xu, X.-Q., Wang, X.-X., & Dao, G.-H. (2016) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2016.02.008 · Cited by 124
Development of a foam flotation system for harvesting microalgae biomass
Coward, T., Lee, J. G. M., & Caldwell, G. S. (2013) · Algal Research · doi:10.1016/j.algal.2012.12.001 · Cited by 122
Utilisation of Chlorellavulgaris cell biomass for the production of enzymatic protein hydrolysates
Morris, H. J., Almarales, Á., Carrillo-Farnés, O., & Bermúdez, R. C. (2008) · Bioresource Technology · doi:10.1016/j.biortech.2008.01.080 · Cited by 124
“E-mail address: hmorris@cebi.uo.edu.cu (H.J. Morris). and food supplements (Iwamoto, 2003; Merchant et al., 2002; Oh-Hama and Miyachi, 1988; Pulz and Gross, 2004).”
Microalgae Bioactive Compounds to Topical Applications Products—A Review
Martínez-Ruiz, M., Martínez-González, C. A., Kim, D.-H., Santiesteban-Romero, B., Reyes-Pardo, H., Villaseñor-Zepeda, K. R., Meléndez-Sánchez, E. R., Ramírez-Gamboa, D., Díaz-Zamorano, A. L., Sosa‐Hernández, J. E., et al. (2022) · Molecules · doi:10.3390/molecules27113512 · Cited by 130
Microalgae: a potential plant for energy production
Randrianarison, G., & Ashraf, M. A. (2017) · Geology Ecology and Landscapes · doi:10.1080/24749508.2017.1332853 · Cited by 122
“It is astonishing from a physiological point of view that to date only approximately 30 microalgal species are economically used (Pulz & Gross, 2004).”
BackgroundMicroalgae-based pharmaceuticals and nutraceuticals: an emerging field with immense market potential
Jha, D., Jain, V., Sharma, B., Kant, A., & Garlapati, V. K. (2017) · ChemBioEng Reviews · doi:10.1002/cben.201600023 · Cited by 121
Furmaniak, M. A., Misztak, A. E., Franczuk, M. D., Wilmotte, A., Waleron, M., & Waleron, K. F. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.02541 · Cited by 121
Masarin, F., Cedeno, F. R. P., Chavez, E. G. S., de Oliveira, L. E., Gelli, V. C., & Monti, R. (2016) · Biotechnology for Biofuels · doi:10.1186/s13068-016-0535-9 · Cited by 123
“The replacement of fossil fuels with biofuels derived from algae reduces GHG emissions from transportation [14, 15].”
The effect of nitrogen limitation on the physiology and metabolism of chlorella vulgaris var L3
Ikaran, Z., Suárez-Álvarez, S., Urreta, I., & Castañón, S. (2015) · Algal Research · doi:10.1016/j.algal.2015.04.023 · Cited by 124
“Besides, Chlorella cultures have been carried out on a large scale for over five decades to produce high-protein biomass suitable for healthy food, mariculture feed and as bio-filter for wastewater treatments [3,4].”
BackgroundEmerging industrial applications of microalgae: challenges and future perspectives
Udayan, A., Pandey, A. K., Sharma, P., Sreekumar, N., & Kumar, S. (2021) · Systems Microbiology and Biomanufacturing · doi:10.1007/s43393-021-00038-8 · Cited by 127
Oey, M., Ross, I. L., Stephens, E., Steinbeck, J., Wolf, J., Radzun, K. A., Kügler, J. H., Ringsmuth, A. K., Kruse, O., & Hankamer, B. D. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061375 · Cited by 118
“This is because well-designed microalgae systems can be located on non-arable land, cultivated at least in part using saline and waste water, enable increased nutrient recycling and achieve higher yields than crop plants, due to the ability to optimize light distribution, CO2 supply and production conditions [9].”
BackgroundNew structural insights into the cell-wall polysaccharide of the diatom Phaeodactylum tricornutum
Costaouëc, T. L., Unamunzaga, C., Mantecón, L., & Helbert, W. (2017) · Algal Research · doi:10.1016/j.algal.2017.07.021 · Cited by 118
Hoffmann, M., Marxen, K., Schulz, R., & Vanselow, K. (2010) · Marine Drugs · doi:10.3390/md8092526 · Cited by 118
“Therefore, it has been widely discussed in recent years whether microalgae can be used for the production of biofuel and biodiesel [4,8–11].”
BackgroundMicroalgae as a boon for sustainable energy production and its future research & development aspects
Kirrolia, A., Bishnoi, N. R., & Singh, R. (2013) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2012.12.003 · Cited by 117
Quality analysis of commercial Chlorella products used as dietary supplement in human nutrition
Görs, M., Schumann, R., Hepperle, D., & Karsten, U. (2009) · Journal of Applied Phycology · doi:10.1007/s10811-009-9455-4 · Cited by 117
“They can be added to noodles, chewing gum, beer, tea, bread or soft drinks (Pulz and Gross 2004; Spolaore et al. 2006; Liang et al. 2004) or they serve as a natural stain.”
BackgroundGüneş, S., Tamburacı, S., Dalay, M. C., & Gurhan, İ. D. (2017) · Pharmaceutical Biology · doi:10.1080/13880209.2017.1331249 · Cited by 119
“They are represented in sun protection creams and hair care products with these UV protective compounds (Pulz & Gross 2004; Kim 2011).”
BackgroundGiwa, A., Adeyemi, I. A., Dindi, A., Lopez, C. G.-B., Lopresto, C. G., Curcio, S., & Chakraborty, S. (2018) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2018.02.032 · Cited by 117
Electrotechnologies applied to microalgal biotechnology – Applications, techniques and future trends
Geada, P., Rodrigues, R. M. M., Loureiro, L., Pereira, R. N., Fernandes, B. D., Teixeira, J. A., Vasconcelos, V. M., & Vicente, A. A. (2018) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2018.06.059 · Cited by 116
“Furthermore, PUFAs are thought to play an important role on cardio-circulatory and coronary heart diseases, as well as on treatment of atherosclerosis, hypertension, cholesterol and cancer [23].”
BackgroundInfluentialProcess for selective extraction of pigments and functional proteins from Chlorella vulgaris
Kulkarni, S., & Nikolov, Z. L. (2018) · Algal Research · doi:10.1016/j.algal.2018.08.024 · Cited by 117
Microalgal Cultivation for Value-Added Products: A Critical Enviro-Economical Assessment
Kothari, R., Pandey, A., Ahmad, S., Kumar, A., Pathak, V. V., & Tyagi, V. V. (2017) · 3 Biotech · doi:10.1007/s13205-017-0812-8 · Cited by 116
“…microalgae like Spirulina, Chlorella, Dunaliella, Nostoc, and Aphanizomenon, etc, has been speculated 3000, 2000, 1200, 600, and 500 ton per year, respectively (Pulz and Gross 2004), and these microalgal biomass extracts is being used by various industries for its high-value chemical compounds.”
BackgroundInfluentialEffects of abiotic stressors on lutein production in the green microalga Dunaliella salina
Fu, W., Paglia, G., Magnúsdóttir, M., Steinarsdóttir, E. A., Guðmundsson, S., Palsson, B. Ø., Andrésson, Ó. S., & Brynjólfsson, S. (2014) · Microbial Cell Factories · doi:10.1186/1475-2859-13-3 · Cited by 116
“Background Photosynthetic microalgae have recently been exploited for the commercial production of foods, feeds and cosmetics, as well as active pharmaceutical ingredients [1-5].”
BackgroundGarcía‐Segovia, P., Pagán, M. J., Lara, I. F., & Martı́nez-Monzó, J. (2017) · Food Science and Technology International · doi:10.1177/1082013217700259 · Cited by 123
“Microalgae have received increasing attention because they represent one of the most promising sources of compounds with biological activity that could be used as functional ingredients (Buono et al., 2014; Da Silva Vaz et al., 2016; Pulz and Gross, 2004).”
BackgroundCommercially important bioproducts from microalgae and their current applications—A review
Mobin, S. M. A., Chowdhury, H., & Alam, F. (2019) · Energy Procedia · doi:10.1016/j.egypro.2019.02.183 · Cited by 115
Kumar, M., Kulshreshtha, J., & Singh, G. P. (2011) · Brazilian Journal of Microbiology · doi:10.1590/s1517-83822011000300034 · Cited by 129
Factors Affecting Growth of Various Microalgal Species
Loganathan, B. G., Orsat, V., & Lefsrud, M. G. (2018) · Environmental Engineering Science · doi:10.1089/ees.2017.0521 · Cited by 125
“An estimate from Pulz and Gross (2004) indicated that the retail value of products acquired from microalgae was about US$ 5–6.5 billion and this was generated by diverse sectors such as health and food (US$ 1.25–2.5 billion), aquaculture (700 million), and through DHA (docosahexaenoic acid) omega-3…”
InfluentialBhatia, L., Bachheti, R. K., Garlapati, V. K., & Chandel, A. K. (2020) · Biomass Conversion and Biorefinery · doi:10.1007/s13399-020-00843-6 · Cited by 122
Nitrogen content, dietary fiber, and digestibility in algal food products
Mišurcová, L., Kráčmar, S., Klejdus, B., & Vacek, J. (2010) · Czech Journal of Food Sciences · doi:10.17221/111/2009-cjfs · Cited by 115
“Food algal chemistry and technology were recently discussed (Skulberg 2000; Mundt et al. 2001; Pulz & Gross 2004; Thajuddin & Subramanian 2005; Cardozo et al. 2007; Leflaive & Ten-Hage 2007; Eriksen 2008; Gantar & Svircev 2008).”
BackgroundREVIEWS: The business of biotechnology
Demain, A. L. (2007) · Industrial Biotechnology · doi:10.1089/ind.2007.3.269 · Cited by 115
Metadata
- Authors
- Pulz, O., & Gross, W.
- Affiliations
- Institut für Getreideverarbeitung (Germany) (DE)
- Freie Universität Berlin (DE)
- Corresponding author
- Pulz, Otto
- Venue
- Applied Microbiology and Biotechnology
- Published
- 2004-08-06
- Volume
- 65
- Issue
- 6
- Pages
- 635-648
- ISSN
- 0175-7598 (ISSN-L)
- 1432-0614
- OpenAlex
- W2044809902
- Cited by
- 2,132
- References
- 40
- Citations by year
- 2026: 56 · 2025: 82 · 2024: 119 · 2023: 104 · 2022: 109 · 2021: 150 · 2020: 169 · 2019: 152 · 2018: 124 · 2017: 127 · 2016: 134 · 2015: 162 · 2014: 152 · 2013: 132 · 2012: 107
- FWCI
- 2.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Applied Microbiology and Biotechnology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Keywords
- microalgae, microalgal biotechnology, microalgal biomass, food and feed, genetic engineering of microalgae, pharmaceutical applications, ecological applications, screening method
- MeSH terms
- Biotechnology, Drug Industry, Food Industry, Eukaryota
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