The DOI matches its Crossref record; 39 of the 40 references it cites were found in a registry or an index.
Valuable products from biotechnology of microalgae
Abstract
The biotechnology of microalgae has gained considerable importance in recent decades. Applications range from simple biomass production for food and feed to valuable products for ecological applications. For most of these applications, the market is still developing and the biotechnological use of microalgae will extend into new areas. Considering the enormous biodiversity of microalgae and recent developments in genetic engineering, this group of organisms represents one of the most promising sources for new products and applications. With the development of sophisticated culture and screening techniques, microalgal biotechnology can already meet the high demands of both the food and pharmaceutical industries.
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“Due to their simple cultivation with high protein content and nutritional value, Chlorella and Arthrospira platensis are at the forefront of the microalgal market [63,78].”
From Challenges in Functional Food Products with the Incorporation of Some Microalgae (2024) · cites this paper as [63]
In the citing paper
“Algae are produced in quantity and sold directly as food and nutrient supplements, while their processed products or extracts are used in biopharmaceuticals and cosmetics [5–7].”
In the citing paper
“The world energy crisis in the 1970s led to the identification of algae as renewable and sustainable sources for biofuels production, prompting the exploration of microalgae as a new field of research for fuels and other valuable products [10, 140].”
From The promising future of microalgae: Current status, challenges, and optimization of a sustainable and renewable industry for biofuels, feed, and other products (2018) · cites this paper as [140]
In the citing paper
“According to one estimate, about 5000 metric tons of dry algal biomass processed for bioproducts generates US$ 1.25 × 109 each year [140].”
From The promising future of microalgae: Current status, challenges, and optimization of a sustainable and renewable industry for biofuels, feed, and other products (2018) · cites this paper as [140]
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Dual potential of microalgae as a sustainable biofuel feedstock and animal feed
Lum, K. K., Kim, J., & Lei, X. G. (2013) · Journal of Animal Science and Biotechnology · doi:10.1186/2049-1891-4-53 · Cited by 276
“Microalgal solubility is high at alkaline conditions [74].”
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“The fatty acid content of cells reflects their energy content as a feed or fuel [1, 2], as well as the yield of products such as long chain polyunsaturated fatty acids, lipid extracts for pharmaceuticals, cosmetics and nutraceuticals [ 1 , 3] and fatty acid methyl esters (FAME) for biodiesel.”
BackgroundEl‐Naggar, N. E., Hussein, M. H., Shaaban-Dessouki, S. A., & Dalal, S. R. (2020) · Scientific Reports · doi:10.1038/s41598-020-59945-w · Cited by 286
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“Several other heterotrophic processes that utilise microalgae have been established at laboratory scale to deliberately enrich the biomass with compounds such as pigments and antioxidants (Pulz and Gross 2004; Raja et al. 2008; Spolaore et al. 2006).”
BackgroundThe potential of microalgae and their biopolymers as structuring ingredients in food: A review
Bernaerts, T. M. M., Gheysen, L., Foubert, I., Hendrickx, M. E., & Van Loey, A. M. (2019) · Biotechnology Advances · doi:10.1016/j.biotechadv.2019.107419 · Cited by 271
The Potential of Microalgae for the Production of Bioactive Molecules of Pharmaceutical Interest
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“565 Indeed, Pulz & Gross [12] pointed out that the maximum specific growth rate of Chlorella vulgaris and 566 Haematococcus pluvialis growing mixotrophically was the sum of the photosynthetic and heterotrophic specific 567 growth rates.”
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Effects of shear stress on microalgae- A Review
Wang, C., & Lan, C. Q. (2018) · Biotechnology Advances · doi:10.1016/j.biotechadv.2018.03.001 · Cited by 269
“particularly valuable product is docosahexanoic acid (DHA) (Pulz and Gross, 2004), an omega-3 fatty acid that is essential for human health (Mendes et al.”
BackgroundEvaluation of antioxidant properties and total phenolic contents of some strains of microalgae
Hajimahmoodi, M., Faramarzi, M. A., Mohammadi, N., Soltani, N., Oveisi, M. R., & Nafissi‐Varcheh, N. (2009) · Journal of Applied Phycology · doi:10.1007/s10811-009-9424-y · Cited by 266
“…Biology, ACECR, Research Institute of Applied Science, Tehran, Iran N. Nafissi-Varcheh Department of Pharmaceutical Biotechnology, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, P.O. Box 14155-6153, Tehran, Iran effects on the health of man and animals (Pulz and Gross 2004).”
BackgroundA review on microalgae, a versatile source for sustainable energy and materials
Satyanarayana, K. G., Mariano, A. B., & VARGAS, J. V. C. (2010) · International Journal of Energy Research · doi:10.1002/er.1695 · Cited by 265
“Meanwhile the market for microalgae to produce the biomass to be used mostly in health food, animal feed and aquaculture is fast growing with an estimated retail value of US$ 3000–4000 million [49].”
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Roy, S. S., & Pal, R. (2014) · Proceedings of the Zoological Society · doi:10.1007/s12595-013-0089-9 · Cited by 264
“They are required for larvae nutrition during a brief period of life cycle and are used either for direct con- sumption or indirectly as prepared feed.”
BackgroundLaurens, L. M. L., Markham, J., Templeton, D. W., Christensen, E. D., Van Wychen, S., Vadelius, E. W., Chen-Glasser, M., Dong, T., Davis, R., & Pienkos, P. T. (2017) · Energy & Environmental Science · doi:10.1039/c7ee01306j · Cited by 260
Effects of Spirulina Biomass on the Technological and Nutritional Quality of Bread Wheat Pasta
Rodríguez De Marco, E., Steffolani, M. E., Martínez, C. S., & León, A. E. (2014) · LWT - Food Science and Technology · doi:10.1016/j.lwt.2014.02.054 · Cited by 257
Advances in the Production of High-Value Products by Microalgae
Leu, S., & Boussiba, S. (2014) · Industrial Biotechnology · doi:10.1089/ind.2013.0039 · Cited by 265
“5,6,12 Microalgal species can be divided into three categories based on their exploitation potential for high-value chemicals production: species dedicated to production of a single high-value product; species with a high potential for exploitation by biorefinery approaches; and novel species with…”
Recent Developments on Genetic Engineering of Microalgae for Biofuels and Bio‐Based Chemicals
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Microalgae-Derived Pigments: A 10-Year Bibliometric Review and Industry and Market Trend Analysis
Silva, S. C., Ferreira, I. C. F. R., Dias, M. M., & Barreiro, M. F. (2020) · Molecules · doi:10.3390/molecules25153406 · Cited by 248
“These compounds show several functional effects, acting as immunomodulators [44], antioxidant, and anti-inflammatory agents [45–47], anticancer and antimicrobials [48], and also show prebiotic effects [49].”
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Valuable bioproducts obtained from microalgal biomass and their commercial applications: A review
Loganathan, B. G., Orsat, V., & Mark, L. (2018) · Environmental Engineering Research · doi:10.4491/eer.2017.220 · Cited by 253
Utilization of algae for biofuel, bio-products and bio-remediation
Mathimani, T., & Pugazhendhi, A. (2018) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2018.12.007 · Cited by 249
Ahmad, A., Hassan, S. W., & BANAT, F. A. (2022) · Bioengineered · doi:10.1080/21655979.2022.2061148 · Cited by 263
“Microalgae also produce a wide range of fatty acids that are useful for the food and feed industry, including gamma-linolenic acid (GLA), linoleic acid (LA), alpha-linolenic acid (ALA), and ARA [99].”
BackgroundHempel, N., Petrick, I., & Behrendt, F. (2012) · Journal of Applied Phycology · doi:10.1007/s10811-012-9795-3 · Cited by 249
“The first step in developing such an algal process is the screening of various strains to choose the most suitable species (Pulz and Gross 2004) with a high productivity of fatty acids.”
BackgroundPathak, J., Rajneesh, Maurya, P. K., Singh, S. P., Häder, D., & Sinha, R. P. (2018) · Frontiers in Environmental Science · doi:10.3389/fenvs.2018.00007 · Cited by 245
“The cyanobacterium Spirulina (Arthrospira) has been used by the Aztec population as food supplement for a long time (Pulz and Gross, 2004).”
BackgroundMethodReview of biological and engineering aspects of algae to fuels approach
Chen, P. L., Min, M., Chen, Y., Wang, L., Li, Y., Chen, Q., Wang, C., Wan, Y., Wang, X., Cheng, Y., et al. (2010) · doi:10.25165/ijabe.v2i4.200 · Cited by 236
“Antioxidant products derived from microalgae, including β-carotene, tocopherol, antioxidant extract, and PUFAs extracts are another commercial application of algal high value chemicals([119]).”
BackgroundInfluentialFunctional ingredients from microalgae
Buono, S., Langellotti, A. L., Martello, A., Rinna, F., & Fogliano, V. (2014) · Food & Function · doi:10.1039/c4fo00125g · Cited by 254
Marxen, K., Vanselow, K., Lippemeier, S., Hintze, R., Ruser, A., & Hansen, U. (2007) · Sensors · doi:10.3390/s7102080 · Cited by 242
“These properties make microalgae and their intracellular substances interesting for business applications (Margalith 1999, Eonseon et al. 2003, Pulz and Gross 2004, Spolaore et al. 2006).”
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“Algal products are currently used in the animal and fish feed industries, and for cosmetics, pigments, and nutraceuticals [1–3].”
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McNeff, C. V., McNeff, L. C., Yan, B., Nowlan, D. T., Rasmussen, M. A., Gyberg, A. E., Krohn, B. J., Fedie, R. L., & Hoye, T. R. (2008) · Applied Catalysis A General · doi:10.1016/j.apcata.2008.03.019 · Cited by 235
Algae as Food in Europe: An Overview of Species Diversity and Their Application
Mendes, M., Navalho, S., Ferreira, A., Paulino, C., Figueiredo, D., Silva, D., Gao, F., Gama, F., Bombo, G., Jacinto, R., et al. (2022) · Foods · doi:10.3390/foods11131871 · Cited by 234
Fatty Acids of Microalgae: Diversity and Applications
Maltsev, Y., & Maltseva, K. (2021) · Reviews in Environmental Science and Bio/Technology · doi:10.1007/s11157-021-09571-3 · Cited by 226
“…Isochrysis, Haematococcus, Dunaliella, Neochloris, Nostoc, Nannochloropsis, Pavlova, Phaeodactina, Porphyridium, Arthrospira, Schizochytrium, Thalassiosira are used for the production of commercial products (Pulz and Gross 2004; Safafar et al. 2016; Sathasivam et al. 2019; Xu et al. 2020).”
BackgroundInfluentialCabanelas, I. T. D., Ruiz, J., Arbib, Z., Chinalia, F. A., Garrido-Pérez, C., Rogalla, F., Nascimento, I. A., & Perales, J. A. (2013) · Bioresource Technology · doi:10.1016/j.biortech.2012.12.152 · Cited by 228
Closed photo-bioreactors as tools for biofuel production
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“However, the combination with the idea of vertical thin films has the potential to lead to high biomass concentration [8].”
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Chojnacka, K. (2012) · The Open Conference Proceedings Journal · doi:10.2174/1876326x01203020020 · Cited by 226
MICROALGAE AND CYANOBACTERIA: FOOD FOR THOUGHT1
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“These organisms are grown on a large scale for food and feed (Robinson and Toerien 1982), aquaculture (Borowitzka 1997), valuable biochemicals (Pulz and Gross 2004), or water treatment and purification (Oswald 1980).”
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The Impact of Microalgae in Food Science and Technology
Matos, Â. P. (2017) · Journal of the American Oil Chemists Society · doi:10.1007/s11746-017-3050-7 · Cited by 222
Algae as a source of renewable chemicals: opportunities and challenges
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LC-PUFA from photosynthetic microalgae: occurrence, biosynthesis, and prospects in biotechnology
Khozin‐Goldberg, I., Iskandarov, U., & Cohen, Z. (2011) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-011-3441-x · Cited by 222
“At present, few photosynthetic species of green microalgae are mainly cultivated on a large scale for the production of high-value constituents for the human health food market (Borowitzka 1988; Pulz and Gross 2004; Spolaore et al. 2006).”
BackgroundSome promising microalgal species for commercial applications: a review.
Mobin, S., & Alam, F. (2017) · Energy Procedia · doi:10.1016/j.egypro.2017.03.177 · Cited by 219
Javed, F., Aslam, M., Rashid, N., Shamair, Z., Khan, A. L., Yasin, M., Fazal, T., Hafeez, A., Rehman, F., Rehman, M. S. U., et al. (2019) · Fuel · doi:10.1016/j.fuel.2019.115826 · Cited by 234
“Microalgae PUFA is used in many other commercial applications such as an 7 additive in infant milk and used in chicken feed to produce eggs enriched with omega-3 [167].”
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Remize, M., Brunel, Y., Silva, J. L., Berthon, J.-Y., & Filaire, E. (2021) · Marine Drugs · doi:10.3390/md19020113 · Cited by 214
“Currently, Chlorella and Arthrospira largely dominate the market [158].”
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“The annual production of Chlorella biomass exceeds 2,000 tonnes [1,2], mostly used for dietary supplements and nutraceuticals, with a minor share destined to the cosmetic market and aquaculture [1].”
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Gouveia, L. (2011) · Springer eBooks · doi:10.1007/978-3-642-17997-6 · Cited by 222
Microalgae cultivation in wastewater: Nutrient removal from anaerobic membrane bioreactor effluent
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“, 2005), promotion of intestinal bacteria (Pulz and Gross, 2004), its effects on HIV-1 replication (Ayehunie et al.”
BackgroundInfluentialMicroalgae as source of polyhydroxyalkanoates (PHAs) — A review
Costa, S. S., Miranda, A. L., de Morais, M. G., Costa, J. A. V., & Druzian, J. I. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.03.099 · Cited by 231
Extremophiles and biotechnology: current uses and prospects
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Acién, F. G., González–López, C. V., Fernández-Sevilla, J. M., & Grima, E. M. (2012) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-012-4362-z · Cited by 211
“The amount of microalgae produced worldwide (5 kt/year; Pulz and Gross 2004) is almost nothing compared to worldwide CO2 emissions (20 Gt/year).”
BackgroundMethodKumar, B. R., Mathimani, T., Sudhakar, M. P., Rajendran, K., Nizami, A.-S., Brindhadevi, K., & Pugazhendhi, A. (2021) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2020.110649 · Cited by 208
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“…(chicken, green circle); Danio rerio (zebrafish, blue circle). pectins, halogenated compounds, toxins, etc., which have been extensively reviewed previously (Pulz and Gross, 2004; Spolaore et al., 2006; Cardozo et al., 2007; Hallmann, 2007; Milledge, 2011; Borowitzka, 2013; Leu and Boussiba, 2014).”
BackgroundMicroalgae as second generation biofuel. A review
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“It is therefore, preferable that the level of polyunsaturated fatty acids in biodiesel is Table 4 Biohydrogen produced by selected cyanobacteria and their characteristics Organism description Organisms name Maximum H2 production (μmol/mg chl a/h) References Heterocystous filamentous cyanobacteria A. cylindrica 0.91–2.…”
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Photobioreactor Design for Commercial Biofuel Production from Microalgae
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Evaluation of Microalgae for use as Nutraceuticals and Nutritional Supplements
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“Global production of Dunaliella is estimated to be 1,200 tons dry weight per year [31].”
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Verseux, C., Baqué, M., Lehto, K., de Vera, J.-P. P., Rothschild, L. J., & Billi, D. (2016) · International Journal of Astrobiology · doi:10.1017/s147355041500021x · Cited by 194
“Cyanobacteria are already used on Earth as a main food source for larvae of many species of fish, zooplankton (itself used for feeding fish larvae), crustaceans and shellfish (Pulz & Gross 2004).”
BackgroundPotential of sponges and microalgae for marine biotechnology
Wijffels, R. H. (2008) · Trends in biotechnology · doi:10.1016/j.tibtech.2007.10.002 · Cited by 201
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“y and almost all grown in open ponds, and biomass is mainly used for as nutritional supplements (Borowitzka 1997; Pulz and Gross 2004).”
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Liu, L., Pohnert, G., & Wei, D. (2016) · Marine Drugs · doi:10.3390/md14100191 · Cited by 199
Perspectives and advances of biological H2 production in microorganisms
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“open reactor systems such as raceway ponds used to produce β-carotene (Borowitzka 1991), food, and health products (Pulz and Gross 2004).”
BackgroundSolar spectral conversion for improving the photosynthetic activity in algae reactors
Wondraczek, L., Batentschuk, M., Schmidt, M. A., Borchardt, R., Scheiner, S., Seemann, B., Schweizer, P., & Brabec, C. J. (2013) · Nature Communications · doi:10.1038/ncomms3047 · Cited by 193
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Fluid-dynamic characterization of real-scale raceway reactors for microalgae production
Mendoza, J. L., Granados, M. R., de Godos, I., Acién, F. G., Molina, E., Banks, C. J., & Heaven, S. (2013) · Biomass and Bioenergy · doi:10.1016/j.biombioe.2013.03.017 · Cited by 189
Strategies for high-level recombinant protein expression in transgenic microalgae: A review
Potvin, G., & Zhang, Z. (2010) · Biotechnology Advances · doi:10.1016/j.biotechadv.2010.08.006 · Cited by 191
“25 billion USD in revenue every year (Pulz and Gross, 2004; Walker et al., 2005a; Spolaore et al., 2006).”
BackgroundPerspectives of microalgal biofuels as a renewable source of energy
Bala, K., Kumar, R., & Deshmukh, D. (2014) · Energy Conversion and Management · doi:10.1016/j.enconman.2014.06.022 · Cited by 191
Potential of microalgae oil from Dunaliella tertiolecta as a feedstock for biodiesel
Tang, H., Abunasser, N., García, M., Chen, M., Ng, K. Y. S., & Salley, S. O. (2010) · Applied Energy · doi:10.1016/j.apenergy.2010.09.013 · Cited by 187
Ghosh, A., Khanra, S., Mondal, M., Halder, G., Tiwari, O. N., Saini, S., Bhowmick, T. K., & Gayen, K. (2016) · Energy Conversion and Management · doi:10.1016/j.enconman.2016.01.050 · Cited by 192
Microalgae for Human and Animal Nutrition
Becker, E. W. (2013) · Wiley eBooks · doi:10.1002/9781118567166.ch25 · Cited by 194
Zanella, L., & Vianello, F. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.103919 · Cited by 205
Health promoting functional lipids from microalgae pool: A review
Katiyar, R., & Arora, A. (2020) · Algal Research · doi:10.1016/j.algal.2020.101800 · Cited by 185
Characterization of microalgal species through TGA/FTIR analysis: Application to nannochloropsis sp.
Marcilla, A. F., Gómez‐Siurana, A., Gomis, C., Fernández, E. C., Catalá, M. C., & Valdés, F. (2008) · Thermochimica Acta · doi:10.1016/j.tca.2008.12.005 · Cited by 184
Garlapati, D., Mathimani, T., Anto, S., Ahamed, T. S., Ananth, D. A., & Pugazhendhi, A. (2019) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2019.119770 · Cited by 188
Meng, Y., Yao, C., Xue, S., & Yang, H. (2014) · Bioresource Technology · doi:10.1016/j.biortech.2013.10.064 · Cited by 174
Guldhe, A., Kumari, S., Ramanna, L., Ramsundar, P., Singh, P., Rawat, I., & Bux, F. (2017) · Journal of Environmental Management · doi:10.1016/j.jenvman.2017.08.012 · Cited by 180
Challenges and opportunities for hydrogen production from microalgae
Oey, M., Sawyer, A. L., Ross, I. L., & Hankamer, B. (2016) · Plant Biotechnology Journal · doi:10.1111/pbi.12516 · Cited by 180
“Microalgae and cyanobacteria systems can be located on nonarable land (and potentially in urban areas and oceans), cultivated at least in part in saline and/or waste water, facilitating increased nutrient and water recycling, and achieve higher yields than crop plants due to the ability to optimize light distribution,…”
BackgroundPotential of Microalgal Compounds in Trending Natural Cosmetics: A Review
Yarkent, Ç., Gürlek, C., & Oncel, S. S. (2020) · Sustainable Chemistry and Pharmacy · doi:10.1016/j.scp.2020.100304 · Cited by 176
Sustainability and cyanobacteria (blue-green algae): facts and challenges
Sharma, N. K., Tiwari, S. P., Tripathi, K., & Rai, A. K. (2010) · Journal of Applied Phycology · doi:10.1007/s10811-010-9626-3 · Cited by 185
“The cyanobacteria consist of a heterogeneous assemblage of oxygen evolving photosynthetic prokaryotes, and are composed of about 150 genera and 2,000 species (Pulz and Gross 2004) including unicellular, colonial, filamentous to branched filamentous forms (Thajuddin and Subramanian 2005).”
BackgroundMethodInfluentialIsolation and Evaluation of Oil-Producing Microalgae from Subtropical Coastal and Brackish Waters
Lim, D. K. Y., Garg, S., Timmins, M., Zhang, E. S. B., Thomas‐Hall, S. R., Schuhmann, H., Li, Y., & Schenk, P. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0040751 · Cited by 181
“Nevertheless, these v-3 polyunsaturated fatty acids (PUFAs) are highly valued in human nutrition and therapeutics [15] and are linked to a wide range of cardio and circulatory benefits [16].”
BackgroundVázquez-Romero, B., Perales, J. A., Pereira, H., Barbosa, M., & Ruiz, J. (2022) · Science of The Total Environment · doi:10.1016/j.scitotenv.2022.155742 · Cited by 180
Costache, T., Acién, F. G., Morales-Amaral, M. D. M., Fernández-Sevilla, J. M., Stamatin, I., & Molina, E. (2013) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-013-5035-2 · Cited by 177
“Microalgae can be used for the production of high-value compounds (Pulz and Gross 2004), wastewater treatment (Muñoz et al. 2009), CO 2 mitigation (Brune et al. 2009; Acien et al. 2012), and bioenergy production (Chisti 2010).”
BackgroundAhmad, A., Buang, A. B., & Bhat, A. H. (2016) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2016.06.084 · Cited by 185
Microalgae culture quality indicators: a review
Elisabeth, B., Rayen, F., & Behnam, T. (2021) · Critical Reviews in Biotechnology · doi:10.1080/07388551.2020.1854672 · Cited by 175
“The process has to be tuned with the adapted algal strain most relevant to the desired valuable end-product [86].”
BackgroundMuys, M., Sui, Y., Schwaiger, B., Lesueur, C., Vandenheuvel, D., Vermeir, P., & Vlaeminck, S. E. (2019) · Bioresource Technology · doi:10.1016/j.biortech.2018.12.059 · Cited by 175
Graziani, G., Schiavo, S., Nicolai, M. A., Buono, S., Fogliano, V., Pinto, G., & Pollio, A. (2012) · Food & Function · doi:10.1039/c2fo30198a · Cited by 180
Watanabe, F., Yabuta, Y., Tanioka, Y., & Bito, T. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf401545z · Cited by 174
Valuable pigments from microalgae: phycobiliproteins, primary carotenoids, and fucoxanthin
Zittelli, G. C., Lauceri, R., Faraloni, C., Benavides, A. M. S., & Torzillo, G. (2023) · Photochemical & Photobiological Sciences · doi:10.1007/s43630-023-00407-3 · Cited by 192
Santamauro, F., Whiffin, F. M., Scott, R. J., & Chuck, C. J. (2014) · Biotechnology for Biofuels · doi:10.1186/1754-6834-7-34 · Cited by 171
“One potential solution is to use an extremophile yeast that thrives at an extreme pH, temperature or salinity that significantly reduces or prevents competing microbial growth [15,16].”
Pourkarimi, S., Hallajisani, A., Alizadehdakhel, A., & Nouralishahi, A. (2019) · Journal of Analytical and Applied Pyrolysis · doi:10.1016/j.jaap.2019.04.015 · Cited by 175
Fu, W., Gudmundsson, O., Feist, A. M., Herjolfsson, G., Brynjolfsson, S., & Palsson, B. Ø. (2012) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2012.07.004 · Cited by 170
“, 2010) as well as in the production of bioactive substances (Lorenz and Cysewski, 2003; Pulz and Gross, 2004).”
A Holistic Approach to Managing Microalgae for Biofuel Applications
Show, P., Tang, M., Nagarajan, D., Ling, T., Ooi, C.-W., & Chang, J.-S. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18010215 · Cited by 169
“The application of microalgae as food is limited due to current food safety regulations [121], but it has been used historically as a dietary supplement.”
BackgroundSerif, M., Dubois, G., Finoux, A.-L., Teste, M.-A., Jallet, D., & Daboussi, F. (2018) · Nature Communications · doi:10.1038/s41467-018-06378-9 · Cited by 165
Gong, Y., Hu, H., Gao, Y., Xu, X., & Gao, H. C. (2011) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/s10295-011-1032-6 · Cited by 168
Sewsynker-Sukai, Y., Faloye, F. D., & Kana, E. B. G. (2016) · Biotechnology & Biotechnological Equipment · doi:10.1080/13102818.2016.1269616 · Cited by 168
“The advantages of using micro-algae as opposed to oil crops (e.g. soybeans) are not limited to the simple structures and high photosynthetic ef fi ciency but also include the ease of cultivation with moderate requirements and capability for wastewater treatment [89].”
Industrial and Biotechnological Applications of Algae: A Review
Sharma, P., & Sharma, N. (2017) · Journal of Advances in Plant Biology · doi:10.14302/issn.2638-4469.japb-17-1534 · Cited by 171
Utilization of the cyanobacteria Anabaena sp. ATCC 33047 in CO2 removal processes
González–López, C. V., Acién, F. G., Fernández-Sevilla, J. M., Fernández, J. F. S., Cerón-García, M. C., & Grima, E. M. (2009) · Bioresource Technology · doi:10.1016/j.biortech.2009.04.070 · Cited by 167
Algal transgenics and biotechnology
Hallmann, A. (2007) · PUB – Publications at Bielefeld University (Bielefeld University) · Cited by 166
Sanzo, G. D., Mehariya, S., Martino, M., Larocca, V., Casella, P., Chianese, S., Musmarra, D., Balducchi, R., & Molino, A. (2018) · Marine Drugs · doi:10.3390/md16090334 · Cited by 166
“In this context, microalgae represent the starting point for the production of natural compounds with a sustainable approach characterized by low environmental impact [6,7].”
BackgroundBiomolecules from Microalgae and Cyanobacteria: Applications and Market Survey
Hachicha, R., Elleuch, F., Hlima, H. B., Dubessay, P., de Baynast, H., Delattre, C., Pierre, G., Hachicha, R., Abdelkafi, S., Michaud, P., et al. (2022) · Applied Sciences · doi:10.3390/app12041924 · Cited by 185
“There are obvious distinctions between Cyanobacteria and microalgae—primarily, the presence of membrane-bound structures in eukaryotic cells acquired during evolution through endosymbiosis [7,11].”
Background
Metadata
- Authors
- Pulz, O., & Gross, W.
- Affiliations
- Institut für Getreideverarbeitung (Germany) (DE)
- Freie Universität Berlin (DE)
- Corresponding author
- Pulz, Otto
- Venue
- Applied Microbiology and Biotechnology
- Published
- 2004-08-06
- Volume
- 65
- Issue
- 6
- Pages
- 635-648
- ISSN
- 0175-7598 (ISSN-L)
- 1432-0614
- OpenAlex
- W2044809902
- Cited by
- 2,132
- References
- 40
- Citations by year
- 2026: 56 · 2025: 82 · 2024: 119 · 2023: 104 · 2022: 109 · 2021: 150 · 2020: 169 · 2019: 152 · 2018: 124 · 2017: 127 · 2016: 134 · 2015: 162 · 2014: 152 · 2013: 132 · 2012: 107
- FWCI
- 2.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Applied Microbiology and Biotechnology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Keywords
- microalgae, microalgal biotechnology, microalgal biomass, food and feed, genetic engineering of microalgae, pharmaceutical applications, ecological applications, screening method
- MeSH terms
- Biotechnology, Drug Industry, Food Industry, Eukaryota
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