Polymeric micelles as mighty nanocarriers for cancer gene therapy: a review

Block copolymer micelles for drug delivery: design, characterization and biological significance

Kataoka, K., Harada, A., & Nagasaki, Y. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(00)00124-1 · Cited by 3,506 · see citing works

Micellar Nanocarriers: Pharmaceutical Perspectives

Torchilin, V. P. (2006) · Pharmaceutical Research · doi:10.1007/s11095-006-9132-0 · Cited by 1,910 · see citing works

Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo

Farokhzad, O. C., Cheng, J., Teply, B. A., Sherifi, I., Jon, S., Kantoff, P. W., Richie, J. P., & Langer, R. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601755103 · Cited by 1,667 · see citing works

Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery

Nishiyama, N., & Kataoka, K. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2006.05.006 · Cited by 1,052 · see citing works

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype

Yin, H., Xue, W., Chen, S., Bogorad, R. L., Benedetti, E., Grompe, M., Koteliansky, V., Sharp, P. A., Jacks, T., & Anderson, D. G. (2014) · Nature Biotechnology · doi:10.1038/nbt.2884 · Cited by 951 · see citing works

Polymeric Micelles in Anticancer Therapy: Targeting, Imaging and Triggered Release

Oerlemans, C., Bult, W., Bos, M. A., Storm, G., Nijsen, J. F. W., & Hennink, W. E. (2010) · Pharmaceutical Research · doi:10.1007/s11095-010-0233-4 · Cited by 951 · see citing works

Block copolymer micelles for drug delivery: Design, characterization and biological significance

Kataoka, K., Harada, A., & Nagasaki, Y. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.013 · Cited by 784 · see citing works

Lipid–polymer hybrid nanoparticles as a new generation therapeutic delivery platform: A review

Hadinoto, K., Sundaresan, A., & Cheow, W. S. (2013) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2013.07.002 · Cited by 711 · see citing works

Triggered destabilisation of polymeric micelles and vesicles by changing polymers polarity: An attractive tool for drug delivery

Rijcken, C. J. F., Soga, O., Hennink, W. E., & van Nostrum, C. F. (2007) · Journal of Controlled Release · doi:10.1016/j.jconrel.2007.03.023 · Cited by 487 · see citing works

pH-sensitive vesicles, polymeric micelles, and nanospheres prepared with polycarboxylates

Felber, A. E., Dufresne, M.-H., & Leroux, J. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.09.006 · Cited by 480 · see citing works

Micelles and nanoparticles for ultrasonic drug and gene delivery

Husseini, G. A., & Pitt, W. G. (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2008.03.008 · Cited by 469 · see citing works

Simultaneous Delivery of siRNA and Paclitaxel via a “Two-in-One” Micelleplex Promotes Synergistic Tumor Suppression

Sun, T., Du, J., Yao, Y., Mao, C., Dou, S., Huang, S., Zhang, P., Leong, K. W., Song, E., & Wang, J. (2011) · ACS Nano · doi:10.1021/nn103349h · Cited by 406 · see citing works

Nanomicellar formulations for sustained drug delivery: strategies and underlying principles

Trivedi, R., & Kompella, U. B. (2010) · Nanomedicine · doi:10.2217/nnm.10.10 · Cited by 358 · see citing works

In vivo toxicity of cationic micelles and liposomes

Knudsen, K. B., Northeved, H., Ek, P. K., Permin, A., Gjetting, T., Andresen, T. L., Larsen, S., Wegener, K. M., Lykkesfeldt, J., Jantzen, K., et al. (2014) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2014.08.004 · Cited by 357 · see citing works

TAT peptide-based micelle system for potential active targeting of anti-cancer agents to acidic solid tumors

Sethuraman, V. A., & Bae, Y. H. (2006) · Journal of Controlled Release · doi:10.1016/j.jconrel.2006.12.008 · Cited by 336 · see citing works

Therapeutic plasmid DNA versus siRNA delivery: Common and different tasks for synthetic carriers

Scholz, C., & Wagner, E. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.11.014 · Cited by 335 · see citing works

Multifunctional Micellar Nanomedicine for Cancer Therapy

Blanco, E., Kessinger, C. W., Sumer, B. D., & Gao, J. (2008) · Experimental Biology and Medicine · doi:10.3181/0808-mr-250 · Cited by 330 · see citing works

Stability of Self-Assembled Polymeric Micelles in Serum

Lu, J., Owen, S. C., & Shoichet, M. S. (2011) · Macromolecules · doi:10.1021/ma200675w · Cited by 299 · see citing works

Engineering of amphiphilic block copolymers for polymeric micellar drug and gene delivery

Xiong, X.-B., Falamarzian, A., Garg, S. M., & Lavasanifar, A. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.04.028 · Cited by 268 · see citing works

Specific mutations induced by triplex-forming oligonucleotides in mice.

Vasquez, K. M., Narayanan, L., & Glazer, P. M. (2000) · Science · doi:10.1126/science.290.5491.530 · Cited by 234 · see citing works

Micelles based on HPMA copolymers☆

Talelli, M., Rijcken, C. J. F., van Nostrum, C. F., Storm, G., & Hennink, W. E. (2009) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.11.029 · Cited by 208 · see citing works

Challenges in CRISPR/CAS9 delivery: potential roles of nonviral vectors

Li, L., He, Z.-Y., Wei, X.-W., Gao, G.-P., & Wei, Y.-Q. (2015) · Human Gene Therapy · doi:10.1089/hum.2015.069 · Cited by 202 · see citing works

Targeted Polymeric Micelles for siRNA Treatment of Experimental Cancer by Intravenous Injection

Christie, R. J., Matsumoto, Y., Miyata, K., Nomoto, T., Fukushima, S., Osada, K., Halnaut, J., Pittella, F., Kim, H. J., Nishiyama, N., et al. (2012) · ACS Nano · doi:10.1021/nn300942b · Cited by 192 · see citing works

Synthesis and Biological Evaluation of a Bioresponsive and Endosomolytic siRNA−Polymer Conjugate

Meyer, M., Dohmen, C., Philipp, A. B., Kiener, D., Maiwald, G., Scheu, C., Ogris, M., & Wagner, E. (2009) · Molecular Pharmaceutics · doi:10.1021/mp9000124 · Cited by 180 · see citing works

Self-assembled biodegradable amphiphilic PEG–PCL–lPEI triblock copolymers at the borderline between micelles and nanoparticles designed for drug and gene delivery

Endres, T., Beck‐Broichsitter, M., Samsonova, O. V., Renette, T., & Kissel, T. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.06.064 · Cited by 175 · see citing works

Sugar-Installed Block Copolymer Micelles: Their Preparation and Specific Interaction with Lectin Molecules

Nagasaki, Y., Yasugi, K., Yamamoto, Y., Harada, A., & Kataoka, K. (2001) · Biomacromolecules · doi:10.1021/bm015574q · Cited by 171 · see citing works

Polymer vectors via controlled/living radical polymerization for gene delivery

Xu, F., & Yang, W. (2011) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2010.11.005 · Cited by 157 · see citing works

Progress of RAFT based polymers in gene delivery

Ahmed, M., & Narain, R. (2012) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2012.09.008 · Cited by 149 · see citing works

Polyion Complex Micelles with Protein-Modified Corona for Receptor-Mediated Delivery of Oligonucleotides into Cells

Vinogradov, S. V., Batrakova, E. V., Li, S., & Kabanov, A. V. (1999) · Bioconjugate Chemistry · doi:10.1021/bc990037c · Cited by 143 · see citing works

Recent development of nonviral gene delivery systems with virus-like structures and mechanisms

Itaka, K., & Kataoka, K. (2008) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2008.09.019 · Cited by 143 · see citing works

Target specific tumor treatment by VEGF siRNA complexed with reducible polyethyleneimine–hyaluronic acid conjugate

Park, K., Lee, M., Kim, K. S., & Hahn, S. K. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.03.018 · Cited by 133 · see citing works

Neutral polymer micelle carriers with pH-responsive, endosome-releasing activity modulate antigen trafficking to enhance CD8+ T cell responses

Keller, S., Wilson, J. T., Patilea-Vrana, G., Kern, H. B., Convertine, A. J., & Stayton, P. S. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.03.041 · Cited by 132 · see citing works

Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors

Ge, Z., Chen, Q., Osada, K., Liu, X., Tockary, T. A., Uchida, S., Dirisala, A., Ishii, T., Nomoto, T., Toh, K., et al. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2013.12.086 · Cited by 129 · see citing works

Application of Living Free Radical Polymerization for Nucleic Acid Delivery

Chu, D. S. H., Schellinger, J. G., Shi, J., Convertine, A. J., Stayton, P. S., & Pun, S. H. (2012) · Accounts of Chemical Research · doi:10.1021/ar200242z · Cited by 121 · see citing works

Thermosensitive Polymeric Micelles for Targeted Drug Delivery

Talelli, M., & Hennink, W. E. (2011) · Nanomedicine · doi:10.2217/nnm.11.91 · Cited by 119 · see citing works

Nonviral Approach for Targeted Nucleic Acid Delivery

Jafari, M., Soltani, M., Naahidi, S., Karunaratne, D. N., & Chen, P. (2012) · Current Medicinal Chemistry · doi:10.2174/092986712803414141 · Cited by 119 · see citing works

Efficient delivery of siRNA using dendritic poly(l-lysine) for loss-of-function analysis

Inoue, Y., Kurihara, R., Tsuchida, A., Hasegawa, M., Nagashima, T., Mori, T., Niidome, T., Katayama, Y., & Okitsu, O. (2007) · Journal of Controlled Release · doi:10.1016/j.jconrel.2007.10.022 · Cited by 115 · see citing works

Smart polymeric micelles for gene and drug delivery

Nishiyama, N., Bae, Y., Miyata, K., Fukushima, S., & Kataoka, K. (2005) · Drug Discovery Today Technologies · doi:10.1016/j.ddtec.2005.05.007 · Cited by 114 · see citing works

Amphiphilic block co-polymers: Preparation and application in nanodrug and gene delivery

Xiong, X.-B., Binkhathlan, Z., Molavi, O., & Lavasanifar, A. (2012) · Acta Biomaterialia · doi:10.1016/j.actbio.2012.03.006 · Cited by 111 · see citing works

Can non-viral technologies knockdown the barriers to siRNA delivery and achieve the next generation of cancer therapeutics?

Guo, J., Bourré, L., Soden, D. M., O’Sullivan, G. C., & O’Driscoll, C. M. (2011) · Biotechnology Advances · doi:10.1016/j.biotechadv.2011.03.003 · Cited by 105 · see citing works

How do polymeric micelles cross epithelial barriers?

Pepić, I., Lovrić, J., & Filipović-Grčić, J. (2013) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2013.04.012 · Cited by 102 · see citing works

Virus-mimetic polymeric micelles for targeted siRNA delivery

Xiong, X.-B., Uludağ, H., & Lavasanifar, A. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.03.075 · Cited by 100 · see citing works

Nanotechnologies and controlled release systems for the delivery of antisense oligonucleotides and small interfering RNA

Fattal, E., & BARRATT, G. M. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00148.x · Cited by 99 · see citing works

Ultrasound-Mediated Local Drug and Gene Delivery Using Nanocarriers

Zhou, Q.-L., Chen, Z., Wáng, Y. X. J., Yang, F., Lin, Y., & Liao, Y. (2014) · BioMed Research International · doi:10.1155/2014/963891 · Cited by 99 · see citing works

Folate receptor mediated intracellular protein delivery using PLL–PEG–FOL conjugate

Kim, S. H., Jeong, J. H., Joe, C. O., & Park, T. G. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2005.01.006 · Cited by 98 · see citing works

PEGylated poly(2-(dimethylamino) ethyl methacrylate)/DNA polyplex micelles decorated with phage-displayed TGN peptide for brain-targeted gene delivery

Qian, Y. J., Zha, Y., Feng, B. C., Pang, Z., Zhang, B., Sun, X., Ren, J., Zhang, C., Shao, X., Zhang, Q., et al. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.11.050 · Cited by 97 · see citing works

Self-assembled siRNA–PLGA conjugate micelles for gene silencing

Hyeon, L. S., Mok, H., Lee, Y., & Park, T. G. (2010) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.12.007 · Cited by 96 · see citing works

Multifunctional Polymeric Micelles Co-loaded with Anti–Survivin siRNA and Paclitaxel Overcome Drug Resistance in an Animal Model of Ovarian Cancer

Salzano, G., Navarro, G., Trivedi, M. S., Rosa, G. D., & Torchilin, V. P. (2015) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-14-0556 · Cited by 92 · see citing works

Dual-purpose magnetic micelles for MRI and gene delivery

Wang, C., Ravi, S., Martinez, G. V., Chinnasamy, V., Raulji, P., Howell, M., Davis, Y., Mallela, J. P., Seehra, M. S., & Mohapatra, S. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.04.030 · Cited by 89 · see citing works

The use of cationic MPEG-PCL-g-PEI micelles for co-delivery of Msurvivin T34A gene and doxorubicin

Shi, S., Shi, K., Tan, L., et al. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.02.010 · Cited by 88 · see citing works

FRET-enabled biological characterization of polymeric micelles

Morton, S. W., Zhao, X., Quadir, M. A., & Hammond, P. T. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.01.027 · Cited by 88 · see citing works

Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles

Vachutinsky, Y., Oba, M., Miyata, K., Hiki, S., Kano, M. R., Nishiyama, N., Koyama, H., Miyazono, K., & Kataoka, K. (2010) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.02.002 · Cited by 88 · see citing works

Tumor targeting by pH-sensitive, biodegradable, cross-linked N-(2-hydroxypropyl) methacrylamide copolymer micelles

Zhou, Z., Li, L., Yang, Y., Xu, X., & Huang, Y. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.04.059 · Cited by 86 · see citing works

In vivo siRNA delivery with dendritic poly( l -lysine) for the treatment of hypercholesterolemia

Watanabe, K., Harada‐Shiba, M., Suzuki, A., Gokuden, R., Kurihara, R., Sugao, Y., Mori, T., Katayama, Y., & Niidome, T. (2009) · Molecular BioSystems · doi:10.1039/b900880b · Cited by 81 · see citing works

Genotoxicity of different nanocarriers: possible modifications for the delivery of nucleic acids.

Shah, V., Taratula, O., Garbuzenko, O. B., Patil, M. L., Savla, R., Zhang, M., & Minko, T. (2013) · PubMed · Cited by 81 · see citing works

Polymeric micelles for enhanced lymphatic drug delivery to treat metastatic tumors

Qin, L., Zhang, F., Lu, X., Wei, X., Wang, J., Fang, X., Si, D., Wang, Y., Zhang, C., Yang, R., et al. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.07.005 · Cited by 80 · see citing works

Paclitaxel-conjugated PEG and arginine-grafted bioreducible poly (disulfide amine) micelles for co-delivery of drug and gene

Nam, K., Nam, H. Y., Kim, P. H., et al. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.07.031 · Cited by 78 · see citing works

Antiangiogenic Gene Therapy of Solid Tumor by Systemic Injection of Polyplex Micelles Loading Plasmid DNA Encoding Soluble Flt-1

Oba, M., Vachutinsky, Y., Miyata, K., Kano, M. R., Ikeda, S., Nishiyama, N., Itaka, K., Miyazono, K., Koyama, H., & Kataoka, K. (2010) · Molecular Pharmaceutics · doi:10.1021/mp9002317 · Cited by 70 · see citing works

Novel polycationic micelles for drug delivery and gene transfer

Zhu, J., Cheng, H. L., Jin, Y., Cheng, S., Zhang, X., & Zhuo, R. (2008) · Journal of Materials Chemistry · doi:10.1039/b801249k · Cited by 69 · see citing works

Grafting of poly(ethylene glycol) to poly-lysine augments its lifetime in blood circulation and accumulation in tumors without loss of the ability to associate with siRNA

Kano, A., Moriyama, K., Yamano, T., et al. (2009) · Journal of Controlled Release · doi:10.1016/j.jconrel.2009.12.007 · Cited by 67 · see citing works

Exploring Polymeric Micelles for Improved Delivery of Anticancer Agents: Recent Developments in Preclinical Studies

Tan, C., Wang, Y., & Fan, W. (2013) · Pharmaceutics · doi:10.3390/pharmaceutics5010201 · Cited by 63 · see citing works

Reconstitutable charged polymeric (PLGA)2-b-PEI micelles for gene therapeutics delivery

Mishra, D., Kang, H. C., & Bae, Y. H. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.01.077 · Cited by 63 · see citing works

Synthesis of Folate-Functionalized RAFT Polymers for Targeted siRNA Delivery

Benoit, D. S. W., Srinivasan, S., Shubin, A. D., et al. (2011) · Biomacromolecules · doi:10.1021/bm200485b · Cited by 61 · see citing works

Nanotoxicity comparison of four amphiphilic polymeric micelles with similar hydrophilic or hydrophobic structure

Zhao, B., Wang, X., Wang, X.-Y., Zhang, H., Dai, W., Wang, J., Zhong, Z., Wu, H., & Zhang, Q. (2013) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-10-47 · Cited by 60 · see citing works

Stearic acid grafted chitosan oligosaccharide micelle as a promising vector for gene delivery system: Factors affecting the complexation

Du, Y., Lu, P., Zhou, J., et al. (2010) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2010.02.017 · Cited by 59 · see citing works

siRNA-Loaded Polyion Complex Micelle Decorated with Charge-Conversional Polymer Tuned to Undergo Stepwise Response to Intra-Tumoral and Intra-Endosomal pHs for Exerting Enhanced RNAi Efficacy

Tangsangasaksri, M., Takemoto, H., Naito, M., Maeda, Y., Sueyoshi, D., Kim, H. J., Miura, Y., Ahn, J., Azuma, R., Nishiyama, N., et al. (2015) · Biomacromolecules · doi:10.1021/acs.biomac.5b01334 · Cited by 59 · see citing works

An Integrated Approach for the Rational Design of Nanovectors for Biomedical Imaging and Therapy

Godin, B., Driessen, W. H. P., Proneth, B., Lee, S., Srinivasan, S., Rumbaut, R. E., Arap, W., Pasqualini, R., Mauro Ferrari, B., & Decuzzi, P. (2010) · Advances in genetics · doi:10.1016/s0065-2660(10)69009-8 · Cited by 58 · see citing works

Enhanced gene expression promoted by the quantized folding of pDNA within polyplex micelles

Osada, K., 塩谷知範, Tockary, T. A., Kobayashi, D., Oshima, H., Ikeda, S., Christie, R. J., Itaka, K., & Kataoka, K. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.09.046 · Cited by 55 · see citing works

Evaluation of polyanion-coated biodegradable polymeric micelles as drug delivery vehicles

Ohya, Y., Takeda, S., Shibata, Y., Ouchi, T., Kano, A., Iwata, T., Mochizuki, S., Taniwaki, Y., & Maruyama, A. (2010) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.11.008 · Cited by 49 · see citing works

The potential of polymeric micelles in the context of glioblastoma therapy

Morshed, R. A., Cheng, Y., Auffinger, B., Wegscheid, M. L., & Lesniak, M. S. (2013) · Frontiers in Pharmacology · doi:10.3389/fphar.2013.00157 · Cited by 49 · see citing works

Neutral Polymeric Micelles for RNA Delivery

Lundy, B. B., Convertine, A. J., Miteva, M., & Stayton, P. S. (2013) · Bioconjugate Chemistry · doi:10.1021/bc300486k · Cited by 47 · see citing works

Receptor-mediated gene delivery by folic acid-modified stearic acid-grafted chitosan micelles

Du, Y., Cai, Li, L., et al. (2011) · International Journal of Nanomedicine · doi:10.2147/ijn.s23828 · Cited by 47 · see citing works

Synthesis and characterization of low molecular weight hyaluronic acid-based cationic micelles for efficient siRNA delivery

Shen, Y., Li, Q., Tu, J., & Zhu, J. (2008) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2008.12.010 · Cited by 44 · see citing works

Combination of chondroitin sulfate and polyplex micelles from Poly(ethylene glycol)-poly{N’-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} block copolymer for prolonged in vivo gene transfection with reduced toxicity

Uchida, S., Itaka, K., Chen, Q., et al. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.04.026 · Cited by 44 · see citing works

RAFT-generated poly(N-isopropylacrylamide)–DNA block copolymers for temperature-responsive formation of polymer micelles

Isoda, K., Kanayama, N., Miyamoto, D., et al. (2010) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2010.11.020 · Cited by 43 · see citing works

Comparative studies of poly(ε-caprolactone) and poly( D , L -lactide) as core materials of polymeric micelles

Theerasilp, M., & Nasongkla, N. (2012) · Journal of Microencapsulation · doi:10.3109/02652048.2012.746746 · Cited by 36 · see citing works

Lectin functionalized nanocarriers for gene delivery

Gajbhiye, V., & Gong, S. (2013) · Biotechnology Advances · doi:10.1016/j.biotechadv.2013.01.005 · Cited by 34 · see citing works

PEG-b-PPS-b-PEI micelles and PEG-b-PPS/PEG-b-PPS-b-PEI mixed micelles as non-viral vectors for plasmid DNA: Tumor immunotoxicity in B16F10 melanoma

Velluto, D., Thomas, S. N., Simeoni, E., et al. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.08.079 · Cited by 33 · see citing works

Convergence of nanotechnology with radiation therapy-insights and implications for clinical translation.

Chatterjee, D. K., Wolfe, T., Lee, J., Brown, A. P., Singh, P. K., Bhattarai, S. R., Diagaradjane, P., & Krishnan, S. (2013) · PubMed · doi:10.3978/j.issn.2218-676x.2013.08.10 · Cited by 31 · see citing works

Varying polymer architecture to deliver drugs

Heath, F., Haria, P., & Alexander, C. (2007) · The AAPS Journal · doi:10.1208/aapsj0902026 · Cited by 28 · see citing works

Small Fragment Homologous Replacement-Mediated Modification of Genomic β -Globin Sequences in Human Hematopoietic Stem/Progenitor Cells

Goncz, K. K., Prokopishyn, N. L., Abdolmohammadi, A., et al. (2006) · Oligonucleotides · doi:10.1089/oli.2006.16.213 · Cited by 27 · see citing works

Effective transgene expression without toxicity by intraperitoneal administration of PEG-detachable polyplex micelles in mice with peritoneal dissemination

Kumagai, M., Shimoda, S., Wakabayashi, R., Kunisawa, Y., Ishii, T., Osada, K., Itaka, K., Nishiyama, N., Kataoka, K., & Nakano, K. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.03.021 · Cited by 27 · see citing works

Bio and nanotechnological strategies for tumor-targeted gene therapy

Kang, J., Toita, R., & Katayama, Y. (2010) · Biotechnology Advances · doi:10.1016/j.biotechadv.2010.06.001 · Cited by 23 · see citing works

Acid Sensitive Polymeric Micelles Combining Folate and Bioreducible Conjugate for Specific Intracellular siRNA Delivery

Yang, Y., Xia, X., Dong, W., Wang, H., Li, L., Ma, P., Sheng, W., Xu, X., & Liu, Y. (2016) · Macromolecular Bioscience · doi:10.1002/mabi.201500389 · Cited by 21 · see citing works

Genotoxicity of Different Nanocarriers: Possible Modifications for the Delivery of Nucleic Acids

Shah, V., Taratula, O., Garbuzenko, O. B., Patil, M. L., Savla, R., Zhang, M., & Minko, T. (2013) · Current Drug Discovery Technologies · doi:10.2174/157016313804998870 · Cited by 21 · see citing works

Preparation of Highly Stable Biodegradable Polymer Micelles by Coating with Polyion Complex

Ohya, Y., Takeda, S., Shibata, Y., Ouchi, T., & Maruyama, A. (2010) · Macromolecular Chemistry and Physics · doi:10.1002/macp.201000167 · Cited by 20 · see citing works

Polymeric Micelles for MCL-1 Gene Silencing in Breast Tumors Following Systemic Administration

Garg, S. M., Falamarzian, A., Vakili, M. R., Aliabadi, H. M., Uludağ, H., & Lavasanifar, A. (2016) · Nanomedicine · doi:10.2217/nnm-2016-0178 · Cited by 20 · see citing works

In Vitro and In Vivo Safety Evaluation of Biodegradable Self-Assembled Monomethyl Poly (Ethylene Glycol)–Poly(ε-Caprolactone)–Poly (Trimethylene Carbonate) Micelles

Yang, X., Cao, D., Wang, N., Sun, L., Li, L., Nie, S., Wu, Q., Liu, X., Cheng, Y., & Gong, C. (2013) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.23800 · Cited by 17 · see citing works

Nanocarrier Mediated Cytosolic Delivery of Drug, DNA and Proteins

Tiwari, S., Gupta, M., & Vyas, S. P. (2012) · Proceedings of the National Academy of Sciences India Section B Biological Sciences · doi:10.1007/s40011-012-0078-1 · Cited by 12 · see citing works

Synthesis of Poly(propylene glycol)‐block‐Polyethylenimine Triblock Copolymers for the Delivery of Nucleic Acids

Brissault, B., Leborgne, C., Scherman, D., et al. (2011) · Macromolecular Bioscience · doi:10.1002/mabi.201000404 · Cited by 10 · see citing works

Phase I and pharmacokinetic study of polymeric micelle-formulated paclitaxel in adult Chinese patients with advanced solid tumors

Lv, F., Cao, J., Zhang, J., Qian, J., Peng, W. J., Sun, S., Li, W., Zhang, W., Guo, W., & Li, J. (2014) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-014-2452-6 · Cited by 8 · see citing works

Impact of Core-Forming Segment Structure on Drug Loading in Biodegradable Polymeric Micelles Using PEG-b-Poly(lactide-co-depsipeptide) Block Copolymers

Takahashi, A., Ozaki, Y., Kuzuya, A., & Ohya, Y. (2014) · BioMed Research International · doi:10.1155/2014/579212 · Cited by 6 · see citing works

Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions

Ghezzi, M., Pescina, S., Padula, C., Santi, P., Del Favero, E., Cantù, L., & Nicoli, S. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.02.031 · Cited by 1,135 · see citing works

Drug repurposing for cancer therapy

Xia, Y., Sun, M., Huang, H., & Jin, W.-L. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01808-1 · Cited by 443 · see citing works

Exosome-mediated delivery of gene vectors for gene therapy

Duan, L., Xu, L., Xu, X., Qin, Z., Zhou, X., Xiao, Y., Liang, Y., & Xia, J. (2021) · Nanoscale · doi:10.1039/d0nr07622h · Cited by 238 · see citing works

Folic acid based carbon dot functionalized stearic acid-g-polyethyleneimine amphiphilic nanomicelle: Targeted drug delivery and imaging for triple negative breast cancer

Sarkar, P., Ghosh, S., & Sarkar, K. (2021) · Colloids and Surfaces B: Biointerfaces · doi:10.1016/j.colsurfb.2020.111382 · Cited by 72 · see citing works

Advanced gene delivery : from concepts to pharmaceutical products

Rolland, A. P. (1999) · Cited by 25 · see citing works

Gene therapy for cardiovascular applications

Pacak, C. A., Mah, C. S., & Byrne, B. J. (2005) · Laboratory techniques in biochemistry and molecular biology · doi:10.1016/s0075-7535(05)31009-6

Targeting of drugs 5 : strategies for oligonucleotide and gene delivery in therapy

Gregoriadis, G. C., & McCormack, B. (1996) · Plenum Press eBooks · Cited by 13 · see citing works

Microbubble-enhanced ultrasound for vascular gene delivery

Lawrie, A., Brisken, A. F., Francis, S., et al. (2000) · Gene Therapy · doi:10.1038/sj.gt.3301339 · Cited by 343 · see citing works

Advance in treatment of rheumatoid arthritis.

Lu, Z. (2010) · Zhongguo redai yixue