Cited by 159Exercise and Physiological ResponsesMuscle metabolism and nutritionAntioxidant Activity and Oxidative Stress

Preventive effects of Spirulina platensis on skeletal muscle damage under exercise-induced oxidative stress

Lu, Hsueh-Kuan, Hsieh, Chin-Cheng, Hsu, Jen-Jung, Yang, Yuh-Kuan, Chou, Hong-Nong·2006·European Journal of Applied Physiology

Abstract

The effects of spirulina supplementation on preventing skeletal muscle damage on untrained human beings were examined. Sixteen students volunteered to take Spirulina platensis in addition to their normal diet for 3-weeks. Blood samples were taken after finishing the Bruce incremental treadmill exercise before and after treatment. The results showed that plasma concentrations of malondialdehyde (MDA) were significantly decreased after supplementation with spirulina (P < 0.05). The activity of blood superoxide dismutase (SOD) was significantly raised after supplementation with spirulina or soy protein (P < 0.05). Both of the blood glutathione peroxidaes (GPx) and lactate dehydrogenase (LDH) levels were significantly different between spirulina and soy protein supplementation by an ANCOVA analysis (P < 0.05). In addition, the lactate (LA) concentration was higher and the time to exhaustion (TE) was significantly extended in the spirulina trail (P < 0.05). These results suggest that ingestion of S. platensis showed preventive effect of the skeletal muscle damage and that probably led to postponement of the time of exhaustion during the all-out exercise.

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Crossref · 10.1007/s00421-006-0263-0

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Authors
Lu, H.-K., Hsieh, C.-C., Hsu, J.-J., Yang, Y.-K., & Chou, H.-N.
Affiliations
  • National Taiwan University of Sport (TW)
  • MingDao University (TW)
  • National Taiwan University (TW)
Corresponding author
Lu, Hsueh-Kuan
Venue
European Journal of Applied Physiology
Published
2006-08-30
Volume
98
Issue
2
Pages
220-226
ISSN
  • 0020-9376 (ISSN-L)
  • 1439-6319
  • 1439-6327
OpenAlex
W2042482402
Cited by
159
References
37
Citations by year
2026: 8 · 2025: 11 · 2024: 13 · 2023: 12 · 2022: 13 · 2021: 13 · 2020: 8 · 2019: 10 · 2018: 8 · 2017: 5 · 2016: 7 · 2015: 8 · 2014: 6 · 2013: 5 · 2012: 8
FWCI
3.76
Type
journal article
Language
en
Open access
closed
Locations
  • European Journal of Applied Physiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
  • Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
Keywords
Spirulina platensis, skeletal muscle injury, exercise-induced oxidative stress, antioxidant supplementation, malondialdehyde, superoxide dismutase, glutathione peroxidase, lactate dehydrogenase, lactate, time to exhaustion, soy protein, treadmill exercise
MeSH terms
Adult, Cyanobacteria, Double-Blind Method, Female, Humans, Male, Exercise, Oxidative Stress, Muscle, Skeletal, Muscle Fatigue, Dietary Supplements, Probiotics

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