Spirulina- An Edible Cyanobacterium with Potential Therapeutic Health Benefits and Toxicological Consequences
Abstract
Spirulina is a blue-green algae which is cultivated not only for its maximum protein content but also due to the presence of other essential nutrients such as carbohydrates and vitamins (A, C and E). It is also a storehouse of minerals including iron, calcium, chromium, copper, magnesium, manganese, phosphorus, potassium, sodium and zinc. Simultaneously, γ- linolenic acid (an essential fatty acid), as well as pigments such as chlorophyll A and phycobiliproteins (C-phycocyanin, allophycocyanin and β-carotene), is also a major component of its rich nutritional profile. Spirulina is known to have various promising effects on the prevention of cancer, oxidative stress, obesity, diabetes, cardiovascular diseases and anemia. Moreover, it also plays a positive role in treating muscular cramps. The safety recommended dosage of Spirulina is approximately 3-10 g/d for adults and it's biological value (BV) is 75 with a net protein utilization (NPU) of 62. Spirulina does not have pericardium due to which it does not hinder the absorption of iron by chelation with phytates or oxalates. On the contrasting note, it may have some adverse effects due to the toxins (microcystins, β-methylamino-L-alanine (BMAA)) produced by Spirulina which might contribute to acute poisoning, cancer, liver damage as well as gastrointestinal disturbances. Its long-term consumption may also lead to the pathogenesis of Alzheimer's disease and Parkinson's disease. The current review focuses on the various aspects of spirulina including its cultivation, nutritional composition, extraction techniques, health benefits, adverse effects, industrial scope and market value which could be beneficial for its utilization in the development of value-added products and supplementary foods due to its high content of protein and bioavailability of nutrients.
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Spirulina can be produced as powder, liquid, oil, tablets, or capsules and is used in food industries including sweets, snacks, and pastries.
“Spirulina algae can be produced in the form of powder, liquid, oil, tablets, or capsules, and are used in many food industries, including the manufacture of sweets, snacks, and pastries.”
From Trends and Technological Advancements in the Possible Food Applications of Spirulina and Their Health Benefits: A Review. (2022) · cites this paper as [7]
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- Authors
- Gogna, S., Kaur, J., Sharma, K., Prasad, R., Singh, J., Bhadariya, V., Kumar, P., & Jarial, S.
- Affiliations
- Lovely Professional University (IN)
- Prince of Songkla University (TH)
- Department of Food Technology and Nutrition, School of Agriculture, Lovely Professional University, Phagwara, Punjab, India
- Corresponding author
- Kaur, Jaspreet
- Venue
- Journal of the American Nutrition Association
- Publisher
- Informa UK Limited
- Published
- 2022-08-02
- Volume
- 42
- Issue
- 6
- Pages
- 559-572
- ISSN
- 2769-7061 (ISSN-L)
- 2769-707X
- OpenAlex
- W4289521185
- Cited by
- 83
- References
- 62
- Citations by year
- 2026: 14 · 2025: 29 · 2024: 26 · 2023: 12 · 2022: 2
- FWCI
- 1.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American Nutrition Association (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Physical Sciences › Environmental Science › Environmental Chemistry › Aquatic Ecosystems and Phytoplankton Dynamics
- Keywords
- Spirulina, cyanobacteria, nutritional composition, protein content, phycocyanin, phycobiliproteins, gamma-linolenic acid, microcystins, BMAA, neurotoxicity, Alzheimer's disease, Parkinson's disease, cancer prevention, oxidative stress, diabetes mellitus, cardiovascular disease, iron bioavailability, dietary supplements, spirulina cultivation, extraction methods, value-added products
- MeSH terms
- Chlorophyll A, Carbohydrates, Iron, Phycobiliproteins, Spirulina
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