Genes that escape from X inactivation

Lanthanum Chloride Inhibits LPS Mediated Expressions of Pro-Inflammatory Cytokines and Adhesion Molecules in HUVECs: Involvement of NF-κB-Jmjd3 Signaling

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Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

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X-inactivation profile reveals extensive variability in X-linked gene expression in females

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Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

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A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome

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UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

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Role of Histone H3 Lysine 27 Methylation in X Inactivation

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The DNA sequence of the human X chromosome

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Kinesin Transports RNA

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Four Evolutionary Strata on the Human X Chromosome

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Tissue-specific expression and regulation of sexually dimorphic genes in mice

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Tsix, a gene antisense to Xist at the X-inactivation centre

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Preferential inactivation of the paternally derived X chromosome in the extraembryonic membranes of the mouse

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A histone H3 lysine 27 demethylase regulates animal posterior development

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X-Linked Mental Retardation and Autism Are Associated with a Mutation in the NLGN4 Gene, a Member of the Neuroligin Family

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The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression

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Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases

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The X-Linked Mental Retardation Gene SMCX/JARID1C Defines a Family of Histone H3 Lysine 4 Demethylases

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What does the “four core genotypes” mouse model tell us about sex differences in the brain and other tissues?

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Steroid sulfatase: molecular biology, regulation, and inhibition

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The Long Noncoding RNA, Jpx, Is a Molecular Switch for X Chromosome Inactivation

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Methylation of Histone H3 at Lys-9 Is an Early Mark on the X Chromosome during X Inactivation

Heard, É., Rougeulle, C., Arnaud, D., Avner, P. R., Allis, C. D., & Spector, D. L. (2001) · Cell · doi:10.1016/s0092-8674(01)00598-0 · Cited by 513 · see citing works

Dosage compensation in mammals: fine-tuning the expression of the X chromosomePreprint

Heard, É., & Distèche, C. M. (2006) · Genes & Development · doi:10.1101/gad.1422906 · Cited by 504 · see citing works

Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin

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X-linked mental retardation

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Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development

Okamoto, I., Patrat, C., Thépot, D., Peynot, N., Fauque, P., Daniel, N., Diabangouaya, P., Wolf, J., Renard, J. P. J. P., Duranthon, V., et al. (2011) · Nature · doi:10.1038/nature09872 · Cited by 465 · see citing works

X-Chromosome inactivation: a repeat hypothesis

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Molecular evidence for a relationship between LINE-1 elements and X chromosome inactivation: The Lyon repeat hypothesis

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The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation

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The short stature homeobox gene SHOX is involved in skeletal abnormalities in Turner syndrome

Clement-Jones, M. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.5.695 · Cited by 421 · see citing works

The <i>Xist</i> RNA Gene Evolved in Eutherians by Pseudogenization of a Protein-Coding Gene

Duret, L., Chureau, C., Samain, S., Weissenbach, J., & Avner, P. (2006) · Science · doi:10.1126/science.1126316 · Cited by 418 · see citing works

The distribution of chromosomal genotypes associated with Turner's syndrome: livebirth prevalence rates and evidence for diminished fetal mortality and severity in genotypes associated with structural X abnormalities or mosaicism

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Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes

Boggs, B. A., Cheung, P., Heard, É., Spector, D. L., Chinault, A. C., & Allis, C. D. (2001) · Nature Genetics · doi:10.1038/ng787 · Cited by 378 · see citing works

Mutations in the JARID1C Gene, Which Is Involved in Transcriptional Regulation and Chromatin Remodeling, Cause X-Linked Mental Retardation

Jensen, L. R., Amende, M., Gurok, U., Moser, B., Gimmel, V., Tzschach, A., Janecke, A. R., Tariverdian, G., Chelly, J., Fryns, J.-P., et al. (2005) · The American Journal of Human Genetics · doi:10.1086/427563 · Cited by 373 · see citing works

Genetics of Early Onset Cognitive Impairment

Ropers, H. (2010) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-082509-141640 · Cited by 365 · see citing works

A review of trisomy X (47,XXX)

Tartaglia, N. R., Howell, S., Sutherland, A., Wilson, R., & Wilson, L. (2010) · Orphanet Journal of Rare Diseases · doi:10.1186/1750-1172-5-8 · Cited by 351 · see citing works

Global survey of escape from X inactivation by RNA-sequencing in mouse

Yang, F., Babak, T., Shendure, J., & Disteche, C. M. (2010) · Genome Research · doi:10.1101/gr.103200.109 · Cited by 350 · see citing works

Sexually dimorphic gene expression in mouse brain precedes gonadal differentiation

Dewing, P., Shi, T., Horvath, S., & Vilain, E. J. N. (2003) · Molecular Brain Research · doi:10.1016/s0169-328x(03)00339-5 · Cited by 348 · see citing works

Preferential expression of the maternally derived X chromosome in the mouse yolk sac

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Molecular Coupling of Xist Regulation and Pluripotency

Navarro, P., Chambers, I., Karwacki-Neisius, V., Chureau, C., Morey, C., Rougeulle, C., & Avner, P. R. (2008) · Science · doi:10.1126/science.1160952 · Cited by 330 · see citing works

LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation

Chow, J., Ciaudo, C., Fazzari, M. J., Mise, N., Servant, N., Glass, J. L., Attreed, M., Avner, P. R., Wutz, A., Barillot, E., et al. (2010) · Cell · doi:10.1016/j.cell.2010.04.042 · Cited by 326 · see citing works

Sex chromosome genes directly affect brain sexual differentiation

Carruth, L. L., Reisert, I., & Arnold, A. P. (2002) · Nature Neuroscience · doi:10.1038/nn922 · Cited by 298 · see citing works

A high density of X-linked genes for general cognitive ability: a run-away process shaping human evolution?

Zechner, U., Wilda, M., Kehrer‐Sawatzki, H., Vogel, W., Fundele, R., & Hameister, H. (2001) · Trends in Genetics · doi:10.1016/s0168-9525(01)02446-5 · Cited by 272 · see citing works

Sex differences in sex chromosome gene expression in mouse brain

Xu, J. (2002) · Human Molecular Genetics · doi:10.1093/hmg/11.12.1409 · Cited by 269 · see citing works

Sex differences in molecular neuroscience: from fruit flies to humans

JAZIN, E. E., & Cahill, L. F. (2009) · Nature reviews. Neuroscience · doi:10.1038/nrn2754 · Cited by 244 · see citing works

Age related reactivation of an X-linked gene

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X inactivation and the complexities of silencing a sex chromosome

Chow, J., & Heard, É. (2009) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2009.04.012 · Cited by 212 · see citing works

Boundaries between Chromosomal Domains of X Inactivation and Escape Bind CTCF and Lack CpG Methylation during Early Development

Filippova, G. N., Cheng, M. K., Moore, J. M., Truong, J.-P., Hu, Y. J., Nguyen, D. K., Tsuchiya, K. D., & Distèche, C. M. (2005) · Developmental Cell · doi:10.1016/j.devcel.2004.10.018 · Cited by 207 · see citing works

Many X-linked microRNAs escape meiotic sex chromosome inactivation

Song, R., Ro, S., Michaels, J. D., Park, C., McCarrey, J. R., & Yan, W. (2009) · Nature Genetics · doi:10.1038/ng.338 · Cited by 206 · see citing works

Gender-Specific Gene Expression in Post-Mortem Human Brain: Localization to Sex Chromosomes

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Escape from X inactivation in mice and humans

Berletch, J. B., Yang, F., & Distèche, C. M. (2010) · Genome biology · doi:10.1186/gb-2010-11-6-213 · Cited by 202 · see citing works

Genetics of intellectual disability

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SATB1 Defines the Developmental Context for Gene Silencing by Xist in Lymphoma and Embryonic Cells

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Sexual differentiation of monoaminergic neurons - genetic or epigenetic?

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The AZFa gene DBY (DDX3Y) is widely transcribed but the protein is limited to the male germ cells by translation control

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Zfy gene expression patterns are not compatible with a primary role in mouse sex determination

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Richer color experience in observers with multiple photopigment opsin genes

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Sex-Specific Differences in Expression of Histone DemethylasesUtxandUtyin Mouse Brain and Neurons

Xu, J., Deng, X., Watkins, R., & Distèche, C. M. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.5382-07.2008 · Cited by 168 · see citing works

The genetic basis of XX-XY differences present before gonadal sex differentiation in the mouse

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Are XX and XY brain cells intrinsically different?

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MAMMALS THAT BREAK THE RULES: Genetics of Marsupials and Monotremes

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Mouse Models for Evaluating Sex Chromosome Effects that Cause Sex Differences in Non‐Gonadal Tissues

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Xist RNA exhibits a banded localization on the inactive X chromosome and is excluded from autosomal material in cis

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Heterogeneous gene expression from the inactive X chromosome: An X-linked gene that escapes X inactivation in some human cell lines but is inactivated in others

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An apparent excess of sex– and reproduction–related genes on the human X chromosome

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Why females are mosaics, x-chromosome inactivation, and sex differences in disease

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A novel mutation in JARID1C/SMCX in a patient with autism spectrum disorder (ASD)

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Large-Scale Population Study of Human Cell Lines Indicates that Dosage Compensation Is Virtually Complete

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RNF12 Activates Xist and Is Essential for X Chromosome Inactivation

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High-resolution analysis of epigenetic changes associated with X inactivationPreprint

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Sexual Dimorphism in Mammalian Autosomal Gene Regulation Is Determined Not Only by Sry but by Sex Chromosome Complement As Well

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The ins and outs of gene regulation and chromosome territory organisation

Heard, É., & Bickmore, W. A. (2007) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2007.04.016 · Cited by 132 · see citing works

Sex-Specific Expression of the X-Linked Histone Demethylase Gene Jarid1c in Brain

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Studying Early Lethality of 45,XO (Turner's Syndrome) Embryos Using Human Embryonic Stem Cells

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Escape from X inactivation

Disteche, C. M., Filippova, G. N., & Tsuchiya, K. D. (2002) · Cytogenetic and Genome Research · doi:10.1159/000071572 · Cited by 116 · see citing works

Escapees on the X chromosome

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Escape from X inactivation of Smcx is preceded by silencing during mouse development

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Escape from X chromosome inactivation is an intrinsic property of the Jarid1c locus

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The spectrum of the behavioral phenotype in boys and adolescents 47,XXY (Klinefelter syndrome).

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X chromosome gene expression in human tissues: Male and female comparisons

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Evidence of Influence of Genomic DNA Sequence on Human X Chromosome Inactivation

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Genomic Environment Predicts Expression Patterns on the Human Inactive X Chromosome

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Differential Proteomics Analysis of Synaptic Proteins Identifies Potential Cellular Targets and Protein Mediators of Synaptic Neuroprotection Conferred by the Slow Wallerian Degeneration (Wld) Gene

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Female-biased expression of long non-coding RNAs in domains that escape X-inactivation in mouse

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Dosage compensation and gene expression on the mammalian X chromosome: one plus one does not always equal two

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Novel human pathological mutations

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Polymorphic X-Chromosome Inactivation of the Human TIMP1 Gene

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A Turner syndrome neurocognitive phenotype maps to Xp22.3

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Transcriptional sexual dimorphism in elongating bovine embryos: implications for XCI and sex determination genes

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Females Are Mosaics: X Inactivation and Sex Differences in Disease

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Genome-Wide Distribution of MacroH2A1 Histone Variants in Mouse Liver Chromatin

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Unravelling the evolutionary origins of X chromosome inactivation in mammals: insights from marsupials and monotremes

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Females Are Mosaics

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Sex differences in brain expression of X- and Y-linked genes

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macroH2A1 Histone Variants Are Depleted on Active Genes but Concentrated on the Inactive X Chromosome

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Comparative Sequence and X-Inactivation Analyses of a Domain of Escape in Human Xp11.2 and the Conserved Segment in MousePreprint

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Telomere shortening relaxes X chromosome inactivation and forces global transcriptome alterations

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