Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer’s disease cases

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Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model

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Subcellular Topography of Neuronal Aβ Peptide in APPxPS1 Transgenic Mice

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APP/PS1KI bigenic mice develop early synaptic deficits and hippocampus atrophy

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Quantification of Modified Amyloid β Peptides in Alzheimer Disease and Down Syndrome Brains

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Intracellular Aβ triggers neuron loss in the cholinergic system of the APP/PS1KI mouse model of Alzheimer's disease

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Consistent immunohistochemical detection of intracellular β-amyloid42 in pyramidal neurons of Alzheimer's disease entorhinal cortex

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Amyloid &amp;#946;-Peptide: The Inside Story

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Association of a Presenilin 1 S170F Mutation With a Novel Alzheimer Disease Molecular Phenotype

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Reduced levels of IgM autoantibodies against N-truncated pyroglutamate Aβ in plasma of patients with Alzheimer's disease

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Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease.

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Biochemistry of Amyloid -Protein and Amyloid Deposits in Alzheimer DiseasePreprint

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Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier

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Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease

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Pyroglutamate Amyloid-β (Aβ): A Hatchet Man in Alzheimer Disease

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N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits

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Focusing the amyloid cascade hypothesis on N-truncated Abeta peptides as drug targets against Alzheimer’s disease

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Coordination of redox active metal ions to the amyloid precursor protein and to amyloid-β peptides involved in Alzheimer disease. Part 2: Dependence of Cu(II) binding sites with Aβ sequences

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Gene Dosage Dependent Aggravation of the Neurological Phenotype in the 5XFAD Mouse Model of Alzheimer’s Disease

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Pyroglutamate-3 Amyloid-β Deposition in the Brains of Humans, Non-Human Primates, Canines, and Alzheimer Disease–Like Transgenic Mouse Models

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Glutaminyl Cyclase in Human Cortex: Correlation with (pGlu)-Amyloid-β Load and Cognitive Decline in Alzheimer's Disease

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Die Amyloidablagerung in einem Mausmodell der Alzheimer Demenz und die Modulation der β-Amyloid-Peptidentstehung durch membranverankerte Inhibitoren

Schieb, H. (2011) · DuEPublico (University of Duisburg-Essen)

The 5XFAD mouse model: a tool for genetic modulation of Alzheime's disease pathology

Jawhar, S. (2012) · doi:10.53846/goediss-3224

SPECIFIC AMYLOID-BETA OLIGOMERS IN HUMAN CEREBROSPINAL FLUID

Handoko, M. (2012) · University of Minnesota Digital Conservancy (University of Minnesota)

Novel Applications of Super-Resolution Microscopy in Molecular Biology and Medical Diagnostics

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Featured Article A phase 1 study to evaluate the safety and pharmacokinetics of PQ912, a glutaminyl cyclase inhibitor, in healthy subjects

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Age-related changes of neuron numbers in the frontal cortex of a transgenic mouse model of Alzheimer's disease Marijke A. M. LemmensAnnerieke S. R. SierksmaBart P. F. Rutten • Frank DennissenHarry W. M. SteinbuschPaul J. LucassenChristoph Schmitz

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Quantitative analysis of neuropathological alterations in two transgenic mouse models of Alzheimer's disease

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In Vitro and In Vivo Studies on Antibodies - N-terminally Truncated Abeta in the 5XFAD Mouse Model

Richard, B. C. (2015) · doi:10.53846/goediss-5098

Therapiemöglichkeiten der Alzheimer-Krankheit durch passive Immunisierung mit dem NT4X-Antikörper im Tg4-42hom-Mausmodell

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Untersuchung genetischer und geschlechtlicher Einflüsse in der Alzheimerpathologie anhand des Maustiermodells 5XFAD

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Studie zur Rolle N-trunkierter Amyloid-β-Peptide bei der Alzheimer-Krankheit

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Studies on the Involvement of the Immune system in Alzheimer's disease

Marcello, A. (2010) · doi:10.53846/goediss-3277

DOI 10.1007/s00702-009-0314-x DEMENTIAS- ORIGINAL ARTICLE Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer’s disease cases

Ingelsson, M., Hannu, Æ., Lars, K. Æ., Thomas, L. Æ., Bayer, A., Wirths, O., Marcello, A., Jawhar, S., Bayer, T. A., Bethge, T., et al. (2013)

Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model

Wirths, O., Breyhan, H., Cynis, H., Schilling, S., Demuth, H.-U., & Bayer, T. A. (2009) · Acta Neuropathologica · doi:10.1007/s00401-009-0557-5 · Cited by 174 · see citing works

The role of N-truncated Aβ peptides in Alzheimer’s Disease

López‐Noguerola, J. S. (2018) · doi:10.53846/goediss-6949

Pyroglutamate-Modified Amyloid-β Protein Demonstrates Similar Properties in an Alzheimer's Disease Familial Mutant Knock-In Mouse and Alzheimer's Disease Brain

Wu, G., Miller, R. A., Connolly, B., Marcus, J., Renger, J. J., & Savage, M. J. (2013) · Neurodegenerative Diseases · doi:10.1159/000353634 · Cited by 31 · see citing works

P4‐023: Pyroglutamyl 3‐42 Abeta Levels are Increased in hAPP tg Mice and Human AD

Christensen, S., Petersen, J., & Helboe, L. (2010) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2010.08.083