Social and behavioral problems of children with agenesis of the corpus callosum
Abstract
Archival data from a survey of parent observations was used to determine the prevalence of social and behavioral problems in children with agenesis of the corpus callosum (ACC). Parent observations were surveyed using the Child Behavior Checklist (CBCL) for 61 children with ACC who were selected from the archive based on criteria of motor development suggesting a relatively high general level of functioning. Younger children with ACC (ages 2-5) were rated as primarily having problems with sleep. Older children with ACC (ages 6-11) manifested problems in attention, social function, thought, and somatic complaints. The older children with ACC were also compared to CBCL data from 52 children with autism who were selected from a previous study. Children with ACC were generally less impaired than children with autism on nearly all scales, with significantly less severe problems in the areas of attention, anxiety/depression, social function, and unusual thoughts. A further questionnaire related to diagnostic criteria for autism indicated that some children with ACC had traits that are among those that contribute to the diagnosis of autism within the domains of social interaction and social communication, but fewer who manifest repetitive and restricted behaviors.
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The results are consistent with evidence from investigations of individuals with agenesis of the corpus callosum.
“Results reported here are consistent with evidence from investigations examining individuals with agenesis of the CC, pointing to the role that this structure plays in complex brain functions.”
From A Meta-Analysis of the Corpus Callosum in Autism (2009) · cites this paper as [47]
Several cognitive and social deficits observed in autism have also been described in individuals with agenesis of the corpus callosum.
“Several cognitive and social deficits observed in autism have also been described in individuals with agenesis of the CC, although not all individuals with these deficits meet full DSM-IV-TR criteria for autistic disorder.”
From A Meta-Analysis of the Corpus Callosum in Autism (2009) · cites this paper as [47]
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- Authors
- Badaruddin, D. H., Andrews, G. L., Bölte, S., Schilmoeller, K. J., Schilmoeller, G., Paul, L. K., & Brown, W. S.
- Affiliations
- Northwest Nazarene University (US)
- Goethe University Frankfurt (DE)
- University of Maine (US)
- Corresponding author
- Brown, Warren S.
- Venue
- Child Psychiatry and Human Development
- Published
- 2007-06-13
- Volume
- 38
- Issue
- 4
- Pages
- 287-302
- ISSN
- 0009-398X (ISSN-L)
- 1573-3327
- OpenAlex
- W2038760265
- Cited by
- 150
- References
- 74
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 6 · 2023: 12 · 2022: 4 · 2021: 12 · 2020: 4 · 2019: 9 · 2018: 7 · 2017: 9 · 2016: 3 · 2015: 12 · 2014: 11 · 2013: 6 · 2012: 15
- FWCI
- 7.29
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Child Psychiatry & Human Development (publishedVersion)
- PubMed (publishedVersion)
- CaltechAUTHORS (California Institute of Technology) (submittedVersion)
- Digital Commons - George Fox University (George Fox University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Fetal and Pediatric Neurological Disorders
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Cerebral Palsy and Movement Disorders
- Keywords
- agenesis of the corpus callosum, attention deficits, sleep disorders, social function, anxiety and depression, autism diagnostic criteria, parent ratings, Child Behavior Checklist, motor development
- MeSH terms
- Autistic Disorder, Child, Child Behavior Disorders, Child, Preschool, Female, Humans, Male, Surveys and Questionnaires, Social Behavior, Agenesis of Corpus Callosum
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