More Evidence that Depressive Symptoms Predict Mortality in COPD Patients: Is Type D Personality an Alternative Explanation?
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BACKGROUND/PURPOSE: The present study attempted to replicate our previous finding that depressive symptoms are a risk factor for mortality in stable chronic obstructive pulmonary disease (COPD), but in a different population with a different measure of depressive symptoms. We further investigated whether type D personality is associated with mortality in patients with COPD and whether it explains any relationship observed between depressive symptoms and mortality. METHODS: In 122 COPD patients, mean age 60.8 +/- 10.3 years, 52% female, and mean forced expiratory volume in 1 s (FEV(1)) 41.1 +/- 17.6%pred, we assessed body mass index, post bronchodilator FEV(1), exercise capacity, depressive symptoms with the Hospital Anxiety and Depression Scale, and type D with the Type D Scale. RESULTS: In the 7 years follow-up, 48 (39%) deaths occurred. The median survival time was 5.3 years. Depressive symptoms (hazard ratio = 1.07, 95% confidence intervals = 1.00-1.14) were an independent risk factor for mortality. Type D was not associated with mortality. CONCLUSIONS: We can rule out type D as an explanation for the relationship between depressive symptoms and mortality observed in this sample. However, ambiguity remains as to the interpretation of the value of depressive symptoms in predicting death.
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Negative findings have been reported for 7-year all-cause mortality in patients with chronic obstructive pulmonary disease for Type D.
“and for 7-year all-cause mortality in patients with chronic obstructive pulmonary disease (COPD) [145]”
From Personality and Longevity: Knowns, Unknowns, and Implications for Public Health and Personalized Medicine (2011) · cites this paper as [145]
These latter two studies reported small to modest elevations in mortality risk for Type D that were not statistically significant.
“These latter two studies reported small to modest elevations in mortality risk for Type D that were not statistically significant.”
From Personality and Longevity: Knowns, Unknowns, and Implications for Public Health and Personalized Medicine (2011) · cites this paper as [145]
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Evans, L., Bell, D., & Smith, S. M. S. (2016) · Chronic Obstructive Pulmonary Disease Open Access · doi:10.21767/2572-5548.100014 · Cited by 7 · see citing works
Steed, L., Heslop-Marshall, K., Sohanpal, R., Saqi-Waseem, S., Kelly, M. J., Pinnock, H., & Taylor, S. J. (2020) · doi:10.21203/rs.3.rs-29318/v1
Steed, L., Heslop-Marshall, K., Sohanpal, R., Saqi-Waseem, S., Kelly, M., Pinnock, H., & Taylor, S. J. (2021) · Figshare · doi:10.6084/m9.figshare.14379552
Steed, L., Heslop-Marshall, K., Sohanpal, R., Saqi-Waseem, S., Kelly, M., Pinnock, H., & Taylor, S. (2021) · Figshare · doi:10.6084/m9.figshare.14379549
de Mol, M., Visser, S., Aerts, J., Lodder, P., van Walree, N., Belderbos, H. N. A., & den Oudsten, B. (2020) · Figshare · doi:10.6084/m9.figshare.12324467
Steed, L., Heslop-Marshall, K., Sohanpal, R., Saqi-Waseem, S., Kelly, M., Pinnock, H., & Taylor, S. (2021) · Figshare · doi:10.6084/m9.figshare.14379543
- Authors
- de Voogd, J. N., Wempe, J. B., Postema, K., van Sonderen, E., Ranchor, A. V., Coyne, J. C., & Sanderman, R.
- Affiliations
- University Medical Center Groningen (NL)
- Venue
- Annals of Behavioral Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-06-10
- Volume
- 38
- Issue
- 2
- Pages
- 86-93
- ISSN
- 0742-5554 (ISSN-L)
- 0883-6612
- 1532-4796
- PMC
- PMC2793382
- OpenAlex
- W2156024202
- Cited by
- 44
- References
- 64
- Citations by year
- 2024: 1 · 2023: 1 · 2021: 4 · 2020: 5 · 2019: 1 · 2018: 1 · 2017: 3 · 2016: 3 · 2015: 5 · 2014: 3 · 2013: 5 · 2012: 3
- FWCI
- 3.38
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- cc-by-nc
- Locations
- Annals of Behavioral Medicine (publishedVersion)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion, cc-by)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- chronic obstructive pulmonary disease, depressive symptoms, mortality, Type D personality, depression as risk factor, replication, Hospital Anxiety and Depression Scale, survival
- MeSH terms
- Aged, Depression, Female, Forced Expiratory Volume, Humans, Male, Middle Aged, Personality, Psychiatric Status Rating Scales, Retrospective Studies, Risk Factors, Multivariate Analysis, Proportional Hazards Models, Pulmonary Disease, Chronic Obstructive, Kaplan-Meier Estimate
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